Fungal arthritis of the knee caused by Mycoleptodiscus indicus.

Abstract:

:Mycoleptodiscus indicus is a recognized plant pathogen which has very rarely been reported as a cause of human infection. It is a tropical or subtropical fungus which is difficult to culture and identify from clinical specimens. This is the first report of septic arthritis with this fungus in a healthy Canadian male. The fungal infection was contracted on a vacation in Costa Rica, probably through direct inoculation through injured skin. The fungus was isolated from synovial fluid and identification was confirmed by DNA sequencing. There has only been one previous case of septic arthritis of the knee and one skin infection reported with this fungus; both cases involved immunocompromised hosts. Both septic arthritis patients required joint surgery and lavage to eradicate the fungus, however, only the immunocompromised patient required antifungal medications. In the future, it is very likely that the number of patients identified with M. indicus infection will rise due to increasing awareness of this pathogen as well as increasing exposure. Many immunocompromised patients on anti-retroviral or biologic therapy are healthy enough to travel, thereby exposing themselves to exotic and infected plants which increase the risk of unusual fungal infections.

journal_name

Clin Rheumatol

journal_title

Clinical rheumatology

authors

Dewar CL,Sigler L

doi

10.1007/s10067-010-1448-9

subject

Has Abstract

pub_date

2010-09-01 00:00:00

pages

1061-5

issue

9

eissn

0770-3198

issn

1434-9949

journal_volume

29

pub_type

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