Insulin and new bone formation in diffuse idiopathic skeletal hyperostosis.

Abstract:

:The tendency of patients with DISH towards obesity or an adult onset of diabetes has been reflected in marked hyperinsulinaemia following glucose challenge. It is hypothesized that insulin at prolonged and high physiologic levels promotes new bone growth, particularly in the entheseal regions. These areas are also subject to various mechanical forces. The resulting new bone produces the radiological changes which characterise DISH.

journal_name

Clin Rheumatol

journal_title

Clinical rheumatology

authors

Littlejohn GO

doi

10.1007/BF02031611

subject

Has Abstract

pub_date

1985-09-01 00:00:00

pages

294-300

issue

3

eissn

0770-3198

issn

1434-9949

journal_volume

4

pub_type

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