Abstract:
:We report a case of a 53-year-old woman diagnosed of systemic sclerosis. She underwent an episode of pulmonary haemorrhage, characterized by haemoptysis, sudden anaemization, and bilateral alveolar infiltration during her hospitalization, which was resolved with steroid treatment. Subsequently, she developed a focal necrotizing glomerulonephritis. After searching in the literature, we have found only three cases of systemic sclerosis associated with pulmonary haemorrhage. We discuss the etiopathogenesis of this association and stress the importance of early steroid therapy.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Alvarez Vega JL,Salazar Vallinas JM,Ortega Alberdi R,Muñoz Sanz A,Turegano JM,Fernandez Alonso Jdoi
10.1007/BF02207098subject
Has Abstractpub_date
1992-03-01 00:00:00pages
116-9issue
1eissn
0770-3198issn
1434-9949journal_volume
11pub_type
杂志文章,评审abstract::Very recently, several studies have convincingly demonstrated the role of infection in the development of the antiphospholipid syndrome. Cross antibody-mediated reactivity due to molecular mimicry between endothelial glycoproteins and microbial products was considered as an important pathogenic mechanism. However, ano...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-006-0352-9
更新日期:2007-03-01 00:00:00
abstract::Infection is a major cause of morbidity and mortality among patients with systemic lupus erythematosus (SLE). To describe the pattern of serious infections in patients with SLE and to identify the predictors of infection-related mortality among SLE patients with serious infections, we prospectively studied all SLE pat...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-018-4102-6
更新日期:2018-08-01 00:00:00
abstract::Visceral leishmaniasis (VL) is a severe disease that can develop in immunocompromised patients. Antitumor necrosis factor-alpha (TNF-alpha) treatment of rheumatoid arthritis can result in clinical benefits, but with an increased risk of opportunistic infections. Leishmania infection in patients treated with TNF-alpha ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-006-0356-5
更新日期:2007-08-01 00:00:00
abstract::The antigens of HLA-DR locus were determined in 127 patients with rheumatoid arthritis and in 175 healthy persons. The frequency of HLA-DR1 antigen was discovered in 45% of the patients and in 22.3% of the examinees from the control group (p less than 0.001). The relative risk is 2.84. 69% of the patients were seropos...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/BF02030241
更新日期:1990-03-01 00:00:00
abstract::Sjõgren's disease is one of the most common rheumatological diseases and can present with a variety of extra-glandular manifestations. Lymphocytic Interstitial Pneumonitis (LIP) is the most common lung pathology in these patients. It is important to know and recognize this condition because it is potentially treatable...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-006-0351-x
更新日期:2007-08-01 00:00:00
abstract::Kikuchi-Fujimoto disease (KFD) or histiocytic necrotizing lymphadenitis is a rare, benign, autoimmune condition characterized by lymphadenopathy, fever, and neutropenia. KFD can frequently mimic various diseases including infection, malignancy, and autoimmune disease. KFD has also been infrequently reported in associa...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-008-0902-4
更新日期:2008-08-01 00:00:00
abstract::The study aimed to determine the serum level of glucocorticoid-induced tumor necrosis factor receptor family-related protein ligand (GITRL) in patients with rheumatoid arthritis (RA) and investigate its clinical significance. GITRL levels were measured by enzyme-linked immunosorbent assay (ELISA) in 88 RA patients, 20...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-016-3280-3
更新日期:2016-09-01 00:00:00
abstract::A 67-year-old woman, suffering from continuous hemoptysis, was admitted to our hospital where she was managed with mechanical ventilation. Computed tomography of the chest demonstrated bilateral massive alveolar hemorrhage without evidence of infectious disease. She was diagnosed with anti-myeloperoxidase antineutroph...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-006-0355-6
更新日期:2007-07-01 00:00:00
abstract::Polymyositis may occur along with other manifestations of chronic graft vs host disease after allogeneic bone marrow transplantation (BMT). Donor lymphocyte infusion (DLI) could produce durable remissions in relapsed patients with chronic myelogenous leukemia (CML) but it may contribute to the development of polymyosi...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-006-0346-7
更新日期:2007-07-01 00:00:00
abstract::There are few reports about the coexistence of Sjögren's syndrome (SS) and ankylosing spondylitis (AS). To evaluate the frequency of SS in patients with AS. We studied 70 patients with AS presenting to the university outpatient clinic between January 2002 and November 2003. All the patients were asked about sicca symp...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-006-0255-9
更新日期:2007-02-01 00:00:00
abstract::To demonstrate an as yet merely postulated generalized osteopathy in psoriatics, the serum calcium level, the alkaline phosphatase in the serum and the urinary excretion of hydroxyproline were evaluated in 24 patients with Ps and 24 patients with PA. Moreover, the bone bioptates from 25 patients with PA and 10 patient...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02208026
更新日期:1991-03-01 00:00:00
abstract::The population of North Dakota is predominantly of Scandinavian (Norwegian) or German descent. We analyzed a cohort of all patients diagnosed with palindromic rheumatism (PR) and followed-up (by the investigator PK) at the St. Alexius Medical Center, Specialty Clinics, Bismarck, North Dakota, from August 16, 2006 to S...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-009-1280-2
更新日期:2010-01-01 00:00:00
abstract::One of the most important therapeutic goal in hyperhidrosis treatment is to seek for the underlying cause and to tailor the treatment accordingly. A detailed history and prompt physical examination are needed to clarify the etiological factor. In this study, we report a 34-year-old woman with a diagnosis of thoracic o...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-006-0400-5
更新日期:2007-08-01 00:00:00
abstract::Small differences in inbred animals with a gene for arthritis must be the cause that some of them evolve the disease and others not. These differences are partly stochastic, caused by thermal movement of molecules. It is possible that their effect is amplified by a network of cytokines, known to play an important role...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF03342643
更新日期:1996-01-01 00:00:00
abstract::Mycobacterium bovis Bacillus Calmette-Guérin (BCG) instillations are used in bladder cancer treatment. Adverse effects can occur. Osteoarticular complications are mainly reactive arthritis, but true infections have been described, such as vertebral osteomyelitis. We made a review of M. bovis BCG vertebral osteomyeliti...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-019-04500-w
更新日期:2019-06-01 00:00:00
abstract::We describe the case of a 26-year-old African female who was treated successfully with belimumab in a case of severe membranous lupus nephritis and retinal vasculitis, resistant to first line therapy. She presented initially with chronic dacryoadenitis and screening showed nephrotic-range proteinuria. Biopsy of the ki...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-015-3153-1
更新日期:2016-06-01 00:00:00
abstract::There is an increasing concern over generalizability of trial results. We investigated eligibility criteria of knee osteoarthritis clinical trials. Eligible trials were randomized, placebo-controlled trials that were identified by searches in MEDLINE, SCOPUS, and the Cochrane Central Register of Controlled Trials. We ...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-013-2342-z
更新日期:2013-11-01 00:00:00
abstract::We present a patient with previously diagnosed hypocomplementemic urticarial vasculitis syndrome, with skin, lung, and renal involvement, who presented with congestive cardiac failure. During the course of her hospitalization, she was also found to have profound proximal muscle weakness in both upper and lower limbs a...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-006-0397-9
更新日期:2007-08-01 00:00:00
abstract::The aim of this study was to investigate the involvement of autonomic nervous system (ANS) function by using power spectral analysis of heart rate variability (HRV) method in patients with ankylosing spondylitis (AS). The study included 94 AS patients all fulfilling the New York criteria for AS, and 49 healthy volunte...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/pl00011198
更新日期:2001-01-01 00:00:00
abstract::The "A disintegrin and metalloprotease" (ADAM) family is thought to play an important role in tissue destruction and inflammatory reactions. ADAM-17 was first described as the protease responsible for tumor necrosis factor (TNF)-α shedding. Here, we have shown the expression of ADAM-17 in inflammatory myopathy and dem...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-018-4014-5
更新日期:2018-04-01 00:00:00
abstract::Perforin and granzyme A co-localize in the cytotoxic granules of killer cells like cytotoxic T lymphocytes (CTL). Perforin is the cytolytic pore-forming protein, whereas the function of the homodimeric serine protease granzyme A and other members of the granzyme family is still unclear. Granzyme A-immunoreactive cells...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02283113
更新日期:1992-12-01 00:00:00
abstract::Systemic lupus erythematosus (SLE) is a multi-system chronic inflammatory disease with a broad spectrum of clinical and serological manifestations. Although clinical evidence of proximal skeletal muscle involvement is not rare in patients with SLE, there is no knowledge about the effects of SLE on the macroscopic stru...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-013-2249-8
更新日期:2013-08-01 00:00:00
abstract::If rheumatoid arthritis (RA) patients with a mild disease course could be identified early in the phase of the disease, therapy with less aggressive and probably less toxic antirheumatic drugs seems to be rational. The aim of this study was to investigate which factors at baseline could predict a clinical response (Am...
journal_title:Clinical rheumatology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1007/s100670050121
更新日期:1999-01-01 00:00:00
abstract::Survival and outcomes have improved considerably among patients with juvenile dermatomyositis (JDM) in the west. However, mortality continues to be high in the developing world. There is paucity of literature on this aspect of JDM from developing countries. We reviewed case files of all patients with JDM registered in...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-014-2747-3
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVES:To establish the prevalence of the associated secondary diseases in patients with Raynaud's phenomenon (RP) attending a rheumatology specialty centre and to determine the frequency with which a secondary illness develops in those having RP, in absence of a well-defined secondary cause. METHODS:118 consecuti...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-003-0726-1
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVES:This study evaluated Superb Microvascular Imaging (SMI) technology for detection of active synovitis in patients with rheumatoid arthritis (RA). METHODS:Between June 2015 and October 2016, 56 patients with RA (42 females; mean age, 53.2 years) underwent gray-scale ultrasound (US) imaging, power Doppler imag...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-019-04550-0
更新日期:2019-09-01 00:00:00
abstract::The relations between parameters obtained by clinical absorptiometric techniques, such as SPA, DPA, DXA and QCT, and geometrical and material parameters of bone structures are investigated. Two types of bone are considered: the diaphysis of a long bone, modelled as a hollow cylindrical structure consisting of compact ...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:
更新日期:1994-12-01 00:00:00
abstract::Behçet's disease is a systemic vasculitic syndrome with unknown etiology. The aim of the present study was to compare the Helicobacter pylori seropositivity and cytotoxin associated gene-A status in patients with Behçet's disease. Ninety-one patients with Behçet's disease and 83 age- and sex-matched persons with or wi...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-006-0416-x
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVE:Antineutrophil cytoplasmic antibodies (ANCAs) are considered a risk factor for granulomatosis with polyangiitis (GPA) exacerbation, especially when staphylococcal superantigens (SAgs) are present in nasal swabs. Their role in monitoring disease activity remains controversial. This study determined the relatio...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-019-04693-0
更新日期:2019-11-01 00:00:00
abstract::The cellular localization of the Ro/SS-A antigen was defined using indirect immunofluorescence and eight monospecific anti- Ro/SS-A antisera which were identified by immunoblotting. Several mammalian tissues were used as substrates. The Ro/SS-A antigen was located mainly in the nucleus of dog liver and Hep-2-cells, an...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02030965
更新日期:1986-01-01 00:00:00