Abstract：
OBJECTIVES:To establish the prevalence of the associated secondary diseases in patients with Raynaud's phenomenon (RP) attending a rheumatology specialty centre and to determine the frequency with which a secondary illness develops in those having RP, in absence of a well-defined secondary cause. METHODS:118 consecutive patients were evaluated. Medical history, physical and laboratory investigations entered into a database. Patients with primary RP and patients with RP who did not fulfil any diagnostic criteria for inclusion in a secondary form were followed up over a three-year period. RESULTS:63 RP patients were found with related conditions. 35 patients met criteria for inclusion in a primary RP group, 20 patients had 'unclassifiable' RP, of which two (10%) developed a well-defined disease. None of the primary RP patients developed a secondary disease. CONCLUSIONS:This study shows that less than 50% of patients with RP attending a rheumatology specialty centre have a connective tissue disease. Patients with isolated RP appear to have a benign disease, since primary RP remains as such, and only a small percentage of patients with 'unclassifiable' RP evolve into a well-defined CTD.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
De Angelis R,Del Medico P,Blasetti P,Cervini Cdoi
10.1007/s10067-003-0726-1subject
Has Abstractpub_date
2003-10-01 00:00:00pages
279-84issue
4-5eissn
0770-3198issn
1434-9949journal_volume
22pub_type
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journal_title：Clinical rheumatology
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pub_type： 杂志文章,评审
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pub_type： 杂志文章,评审
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更新日期：1991-06-01 00:00:00
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pub_type： 临床试验,杂志文章
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