Abstract：
:Macrophage activation syndrome (MAS), which can also be considered as reactive hemophagocytic syndrome (HPS), is a rare and potentially fatal complication of rheumatic diseases. We describe a 42-year-old woman in whom MAS developed as a complication of ankylosing spondylitis (AS). She suffered from fever and low back pain before admission. Laboratory findings were pancytopenia, abnormal liver enzymes, increased ferritin levels, and positive for B27. Hyperplasia of hemophagocytic macrophages was confirmed in her bone marrow. High-dose steroids therapy resulted in clinical and laboratory improvements. In this patient, there was no possible causative factor of HPS (such as viral infection, lymphoma, and systemic lupus erythematosus) except the presence of AS. There have been no previously reported cases describing the relationship between AS and HPS. This case indicates that attention should be given to the possibility that certain patients with AS-associated cytopenia may display accompanying intramedullary hemophagocytic phenomena.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Lou YJ,Jin J,Mai WYdoi
10.1007/s10067-007-0538-9subject
Has Abstractpub_date
2007-11-01 00:00:00pages
1929-30issue
11eissn
0770-3198issn
1434-9949journal_volume
26pub_type
杂志文章abstract：:We and others have previously shown that IL-17 is elevated in the synovial fluid of patients with reactive arthritis (ReA)/undifferentiated spondyloarthropathy (uSpA) having acute synovitis. Major source for IL-17 is Th17 cells, which differentiate from Th0 cells under the influence of TGF-β and IL-6, IL1-β and are ma...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-010-1646-5
更新日期：2011-06-01 00:00:00
abstract：:Juvenile idiopathic arthritis (JIA) is the most common chronic arthritis of childhood. Currently, it is characterized by seven categories. The enthesitis-related arthritis (ERA) category usually affects boys older than 6 years and presents with lower limb asymmetrical arthritis associated with enthesitis. Later, these...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-015-3029-4
更新日期：2015-11-01 00:00:00
abstract：:Behçet's disease (BD) has well-defined pulmonary complications, but cardiopulmonary exercise testing and the strength of the respiratory muscles have not been studied in detail. We aimed to investigate the pulmonary functions tests, inspiratory and expiratory muscle strength and endurance, cardiopulmonary exercise tes...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-006-0508-7
更新日期：2007-09-01 00:00:00
abstract：:We investigated the all-inclusive echocardiographic features in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) within 3 months before and after diagnosis. We reviewed the medical records of 89 AAV patients taking echocardiography and 35 age- and gender-matched controls. We collect...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3868-2
更新日期：2017-12-01 00:00:00
abstract：:Our aim is to investigate the effects of three therapeutic approaches in the chronic low back pain on pain, spinal mobility, disability, psychological state, and aerobic capacity. Sixty patients with chronic low back pain were randomized to three groups: group 1, aerobic exercise + home exercise; group 2, physical the...
journal_title：Clinical rheumatology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10067-007-0815-7
更新日期：2008-07-01 00:00:00
abstract：:The study aims to comprehensively assess the profiles of myositis-specific autoantibodies (MSAs) in Chinese patients with polymyositis (PM)/dermatomyositis (DM) and compare them with a Japanese cohort. One hundred forty-five Chinese patients (68 classic DM, 25 clinically amyopathic DM [CADM], and 52 PM) and 165 Japane...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-015-2935-9
更新日期：2015-09-01 00:00:00
abstract：:Patients with Rheumatic diseases (RDs) are at an increased risk of malignancies compared with the general population. The aim of this study was to examine the relative frequency of several cancers in a single homogeneous cohort of patients with different RDs. Patients diagnosed with rheumatoid arthritis (RA), Ankylosi...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3676-8
更新日期：2018-01-01 00:00:00
abstract：:Two cases of systemic lupus erythematosus (SLE) with autoimmune hepatitis are reported. Both patients had a mild form of SLE without central nervous system or renal involvement and showed a rapid response to corticosteroid therapy. Neither of them had antibodies to mitochondria, smooth muscle, and liver/kidney microso...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02238968
更新日期：1997-05-01 00:00:00
abstract：:The aim of this study was to determine whether the prolactin -1149 G/T polymorphism confers susceptibility to systemic lupus erythematous (SLE) and rheumatoid arthritis (RA). A meta-analysis was conducted for examining the associations between prolactin -1149 G/T polymorphism and susceptibility to SLE or RA using alle...
journal_title：Clinical rheumatology
pub_type： 杂志文章,meta分析
doi：10.1007/s10067-015-2904-3
更新日期：2015-04-01 00:00:00
abstract：:The aim of this study is to find out the outcome of 28 patients who got the diagnosis of primary fibromyalgia (pFM) 26 years ago. In 1986, 56 patients with widespread pain were examined and filled in a base questionnaire (BQ). Of them, 42 fulfilled the Yunus criteria for pFM. Twenty-six years later, addresses of 38 pa...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3967-0
更新日期：2018-05-01 00:00:00
abstract：:Antibodies to beta(2)-glycoprotein I (anti-beta(2)-GPI) have been reported to have stronger association with clinical antiphospholipid syndrome (APS) than anticardiolipin antibodies (aCL) and lupus anticoagulant (LAC). We investigated the sensitivity and specificity of ELISA for anti-beta(2)-GPI in Thai systemic lupus...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-007-0566-5
更新日期：2007-10-01 00:00:00
abstract：:A correlation study was performed on the degree of muscle weakness in 36 patients with dermatomyositis and 69 with polymyositis in relation to muscle biopsy findings, electromyography (EMG) abnormalities, and serum concentrations of creatine kinase (CK), aspartate aminotransferase (AST) and alanine aminotransferase (A...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02030515
更新日期：1990-12-01 00:00:00
abstract：:The effects of vitamin C on 1,25(OH)2D3 synthesis in humans were evaluated; the study included 20 females. They were divided into 2 groups. The first of the 10 subjects (age range 55-71) received ascorbic acid at a dose of 150 mg/die i.v. for 10 days; the second 10 subjects (age range 55-69) received a placebo i.v. fo...
journal_title：Clinical rheumatology
pub_type： 临床试验,杂志文章
doi：10.1007/BF02207657
更新日期：1991-06-01 00:00:00
abstract：:Vitamin D is vital for musculoskeletal health and may be associated with subacute and chronic low back pain. The objective of this study was to estimate the prevalence of vitamin D deficiency among chronic low back pain (CLBP) and subacute low back pain (SLBP), and compare the same with healthy controls. This study wa...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3798-z
更新日期：2018-05-01 00:00:00
abstract：:The objectives of the study were to investigate short and long-term changes and relations to treatment response of plasma interleukin-6 (IL-6), vascular endothelial growth factor (VEGF), YKL-40, matrix metalloproteinase-3 (MMP-3), and total aggrecan in patients with spondyloarthritis (SpA) treated with tumor necrosis ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-010-1528-x
更新日期：2010-11-01 00:00:00
abstract：OBJECTIVES:This study was conducted to assess the safety and efficacy of intra-articular injection of etanercept and compare it with corticosteroid injection in rheumatoid arthritis (RA) patients. METHODS:Fifty patients with RA who suffered from activity in one joint were randomized into two groups, received an intra-...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-020-05235-9
更新日期：2021-02-01 00:00:00
abstract：:We report one case of non-Hodgkin lymphoma in a patient, with a 30-year history of rheumatoid arthritis, taking low dose methotrexate weekly over a 10-month period. The mild immunosuppression that occurs with methotrexate therapy probably places patients with rheumatoid arthritis at added risk of developing lymphoprol...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02231567
更新日期：1993-03-01 00:00:00
abstract：:The first name of the co-author of the above article was presented incorrect in the published version. The author name "Miangliang Qiu" should read "Mingliang Qiu" as mentioned above. ...
journal_title：Clinical rheumatology
pub_type： 已发布勘误
doi：10.1007/s10067-020-04943-6
更新日期：2020-03-01 00:00:00
abstract：:Disability is a common problem in patients with gout. Recently, the Health Assessment Questionnaire Disability Index (HAQ-DI) was recommended for assessing patient reported activity limitations in gout. However, few studies have explored experiences and issues of disability from the perspective of gout patients themse...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-013-2400-6
更新日期：2014-08-01 00:00:00
abstract：:To examine the relationship between physical appearance concern and psychological distress in female adolescent patients with systemic lupus erythematosus (SLE) was the aim of this study. A total of 84 adolescent SLE female patients and 80 age-matching healthy adolescents were evaluated for levels of appearance concer...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-012-2071-8
更新日期：2012-12-01 00:00:00
abstract：:The objective of this study is to assess the usefulness of the stand-alone renal SLICC criterion in patients with childhood systemic lupus erythematosus (cSLE) and report their disease course, treatment response, and outcome. This study included children who were followed regularly in our lupus clinic with proved full...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-019-04789-7
更新日期：2020-02-01 00:00:00
abstract：OBJECTIVES:To compare the efficacy and safety of tocilizumab with those of abatacept in patients with active rheumatoid arthritis not responding to anti-tumor necrosis factor therapy. METHODS:A prospective, open-label study was carried out on adult females with moderate-to-severe rheumatoid arthritis. Patients were ra...
journal_title：Clinical rheumatology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10067-019-04508-2
更新日期：2019-08-01 00:00:00
abstract：:Knee osteoarthritis (KOA) is a common degenerative joint disease causing pain, stiffness, reduced motion, swelling, crepitus, and disability. Several inflammatory markers and cartilage degradation products can be used as biomarkers in OA. The key factors of bone metabolism in normal joint bone, dickkopf-1 (DKK1) and o...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3690-x
更新日期：2017-10-01 00:00:00
abstract：:The aim of this study was to investigate the involvement of autonomic nervous system (ANS) function by using power spectral analysis of heart rate variability (HRV) method in patients with ankylosing spondylitis (AS). The study included 94 AS patients all fulfilling the New York criteria for AS, and 49 healthy volunte...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/pl00011198
更新日期：2001-01-01 00:00:00
abstract：OBJECTIVES:Our aim was to investigate the prevalence value of a high-avidity antinuclear antibody (ANA) of the IgG isotype (HA IgG ANA) compared with that of ANAs of other isotypes in patients with systemic lupus erythematosus (SLE) and to assess the associations of HA IgG ANA with the activity of SLE and lupus nephrit...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-020-05040-4
更新日期：2020-09-01 00:00:00
abstract：:Current Canadian osteoporosis guidelines recommend routine bone density screening of men at age 65. The purpose of this study is to determine the prevalence of osteoporosis in men aged 65-75 in after application of screening guidelines. All males aged 65-75 years who attended a large primary care clinic were advised o...
journal_title：Clinical rheumatology
pub_type： 杂志文章,多中心研究
doi：10.1007/s10067-014-2642-y
更新日期：2015-03-01 00:00:00
abstract：:This study aims to explore the effectiveness of low dose of etanercept (ETN) in patients with ankylosing spondylitis (AS) who achieve a good control of their disease in daily clinical practice. This is a case series of AS patients treated with ETN. According to the judgment of the treating rheumatologist and patient's...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-011-1722-5
更新日期：2011-07-01 00:00:00
abstract：:Physical therapy and exercise (recreational activity) are the cornerstones of non-pharmacologic therapy in axial spondyloarthritis (AxSpA) [1, 2]. These are components of physical activity, though physical activity is made up of activities beyond these and also include occupational activity. Not all activities in AxSp...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-016-3264-3
更新日期：2016-06-01 00:00:00
abstract：:Behçet's disease is a systemic vasculitic syndrome with unknown etiology. The aim of the present study was to compare the Helicobacter pylori seropositivity and cytotoxin associated gene-A status in patients with Behçet's disease. Ninety-one patients with Behçet's disease and 83 age- and sex-matched persons with or wi...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-006-0416-x
更新日期：2007-06-01 00:00:00
abstract：INTRODUCTION:Studies conducted by various scientific societies have shown that the demand for specialized rheumatology care is greater than the projected growth of the workforce. Our research aims to assess the current status of the rheumatology workforce in Latin America. METHOD:This is a descriptive, cross-sectional...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-020-05555-w
更新日期：2021-01-15 00:00:00
