Abstract:
:The level of the N terminal fragment of procollagen III (P3NP) levels of 100 consecutive patients affected by rheumatoid arthritis (RA) were evaluated in comparison with disease activity markers (erythrocytes sedimentation rate, C reactive protein), immunological status (rheumatoid factors, immune complexes) and joint destruction (assessed according to the Steinbrocker index). P3NP levels showed no significant relationship either to disease activity or to immunological status; however, a strong association was fond between X-ray grade and P3NP values. A two-year retrospective study of 32 patients belonging to the original 100 patient population allowed us to assign a predictive value for joint destruction to the P3NP level in the early stage of the disease.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Tebib JG,Viguier P,Noel E,Colson F,Barbier Y,Bouvier Mdoi
10.1007/BF02283106subject
Has Abstractpub_date
1992-12-01 00:00:00pages
502-7issue
4eissn
0770-3198issn
1434-9949journal_volume
11pub_type
杂志文章abstract::With the growing awareness of the impact of chronic back pain and axial spondyloarthritis and recent breakthroughs in genetics and the development of novel treatments which may impact best on early disease, the need for markers that can facilitate early diagnosis and profiling those individuals at the highest risk for...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
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journal_title:Clinical rheumatology
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journal_title:Clinical rheumatology
pub_type: 杂志文章,收录出版,评审
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更新日期:2009-05-01 00:00:00
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pub_type: 杂志文章
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更新日期:1996-01-01 00:00:00
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pub_type: 杂志文章,评审
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journal_title:Clinical rheumatology
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journal_title:Clinical rheumatology
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02715692
更新日期:1984-03-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2010-08-01 00:00:00
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更新日期:2020-06-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2011-08-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-006-0356-5
更新日期:2007-08-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2015-09-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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doi:10.1007/BF02330599
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02214106
更新日期:1989-03-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2016-06-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2007-08-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02031268
更新日期:1984-12-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 临床试验,杂志文章
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更新日期:1991-06-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 杂志文章
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更新日期:1983-09-01 00:00:00