Combination therapy with cyclosporine A and anti-TNF-alpha agents in the treatment of rheumatoid arthritis and concomitant hepatitis C virus infection.

abstract：OBJECTIVE:This case-control study aimed to analyze the clinical features and determine the expression of type I interferon-induced genes in systemic lupus erythematosus (SLE) patients harboring the CD11b rs1143679 single-nucleotide polymorphism (SNP) and elucidate whether it is involved in the relapses of SLE. METHODS...

journal_title：Clinical rheumatology

authors： Xu W,Zhang Y,Wang X,Liu P,Gao D,Gu B,Zhang J,Li C,Ren Q,Yang L,Yuan H,Shen M,Chen X

更新日期：2020-08-12 00:00:00

abstract：OBJECTIVE:To determine the serum levels of Dickkopf-1 (DKK-1) and sclerostin, as well as their correlations with the structural damage assessed by modified stoke ankylosing spondylitis spine score (mSASSS) and the disease activity evaluated by ankylosing spondylitis disease activity score (ASDAS) in patients with ankyl...

journal_title：Clinical rheumatology

authors： Sun W,Tian L,Jiang L,Zhang S,Zhou M,Zhu J,Xue J

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:Adult-onset Still's disease (AOSD) is an autoinflammatory disorder leading to multiorgan involvements. We sought to investigate mood status and the health-related quality of life (HRQoL) in these patients. METHODS:In this study, 82 AOSD patients and 82 age- and sex-matched healthy controls were included. Dem...

journal_title：Clinical rheumatology

authors： Chi H,Jin H,Wang Z,Feng T,Zeng T,Shi H,Wu X,Wan L,Teng J,Sun Y,Liu H,Cheng X,Ye J,Hu Q,Zhou Z,Gu J,Jia J,Liu T,Qiao X,Yang C,Su Y

更新日期：2020-12-01 00:00:00

abstract：:The aim of our study was to explore the relationship between circulating T cells and ankylosing spondylitis (AS) and to find the role of the CD8+CD122+ T cells in the pathogenesis and progression of AS. With the method of case-control design, flow cytometry was performed to quantitatively determine the percentage of c...

journal_title：Clinical rheumatology

authors： Han R,Yang X,Chen M,Zhang X,Yuan Y,Hu X,Wang M,Liu R,Ma Y,Yang J,Xu S,Shuai Z,Jiang S,Pan F

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:This study aimed to identify the clinical characteristics of systemic lupus erythematosus-primary biliary cholangitis (SLE-PBC) patients and to compare the manifestations and prognosis with systemic lupus erythematosus (SLE) patients. METHODS:Twenty-one inpatients with concomitant SLE and primary biliary cho...

journal_title：Clinical rheumatology

authors： Cheng C,Wang Z,Wang L,Zhao J,Wang Q,Tian X,Li M,Zeng X

更新日期：2020-10-16 00:00:00

abstract：:The aim of this study was to investigate whether calcium pyrophosphate dihydrate (CPPD) crystals are constantly detectable in sequential synovial fluid (SF) examinations of patients with initially CPPD-positive osteoarthritis (OA). For this purpose, we searched our SF database for CPPD-positive patients, who had two o...

journal_title：Clinical rheumatology

authors： Robier C,Neubauer M,Fritz K,Lippitz P,Stettin M,Rainer F

更新日期：2013-05-01 00:00:00

abstract：:Transient receptor potential melastatin 7 (TRPM7) is involved in both normal physiological processes and pathology of various diseases. The purpose of this study was to explore the function and underlying mechanisms of TRPM7 channels in rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLSs) apoptosis induced by...

journal_title：Clinical rheumatology

authors： Li X,Wang X,Wang Y,Li X,Huang C,Li J

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVES:There are no pharmacovigilance studies on adverse event (AE) data for tumour necrosis factor alpha (TNFα) inhibitors in South Korea. We analysed AEs induced by adalimumab, infliximab, and etanercept METHODS: We used data from the Korea Institute of Drug Safety and Risk Management-Korea Adverse Events Reporti...

journal_title：Clinical rheumatology

authors： Ha D,Lee SE,Song I,Lim SJ,Shin JY

更新日期：2020-02-01 00:00:00

abstract：:Biological agents, particularly anti-Tumour Necrosis Factor (TNF)-α agents, have emerged as an effective treatment in patients with chronic inflammatory diseases. An association between anti-TNF-α antibodies and reactivation of latent tuberculosis infection (LTBI) has been established. Appropriate screening for TB inf...

journal_title：Clinical rheumatology

authors： Mínguez S,Latorre I,Mateo L,Lacoma A,Diaz J,Olivé A,Domínguez J

更新日期：2012-05-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is well known to affect many different organ systems. Previous work suggests that this includes the auditory system and that measures of hearing may be related to indices of RA disease activity. The aims of this study were to determine whether hearing loss in young subjects with rheumatoid ar...

journal_title：Clinical rheumatology

authors： Murdin L,Patel S,Walmsley J,Yeoh LH

更新日期：2008-05-01 00:00:00

abstract：:Two patients with coexistent Down's syndrome and gout are described. Although increased serum urate levels are frequently reported in Down's syndrome, only a few such patients have been described with concomitant gout. In our patients no significant alterations of the purine salvage pathway were found, and the turnove...

journal_title：Clinical rheumatology

authors： Ciompi ML,Bazzichi LM,Bertolucci D,Mazzoni MR,Barbieri P,Mencacci S,Macchia D,Mariani G

更新日期：1984-06-01 00:00:00

abstract：:This study quantified the association between recreational physical activity and daily function in women with fibromyalgia, and determined if this association is mediated by symptoms of pain, depression, or body mass. Twenty-three women diagnosed with fibromyalgia participated in an observational survey study. Recreat...

journal_title：Clinical rheumatology

authors： Umeda M,Corbin LW,Maluf KS

更新日期：2015-01-01 00:00:00

abstract：:The antigens of HLA-DR locus were determined in 127 patients with rheumatoid arthritis and in 175 healthy persons. The frequency of HLA-DR1 antigen was discovered in 45% of the patients and in 22.3% of the examinees from the control group (p less than 0.001). The relative risk is 2.84. 69% of the patients were seropos...

journal_title：Clinical rheumatology

authors： Jajić Z,Jajić I,Jajić I,Kerhin-Brkljacic V

更新日期：1990-03-01 00:00:00

abstract：:A correlation study was performed on the degree of muscle weakness in 36 patients with dermatomyositis and 69 with polymyositis in relation to muscle biopsy findings, electromyography (EMG) abnormalities, and serum concentrations of creatine kinase (CK), aspartate aminotransferase (AST) and alanine aminotransferase (A...

journal_title：Clinical rheumatology

authors： Tymms KE,Beller EM,Webb J,Schrieber L,Buchanan WW

更新日期：1990-12-01 00:00:00

abstract：:The "A disintegrin and metalloprotease" (ADAM) family is thought to play an important role in tissue destruction and inflammatory reactions. ADAM-17 was first described as the protease responsible for tumor necrosis factor (TNF)-α shedding. Here, we have shown the expression of ADAM-17 in inflammatory myopathy and dem...

journal_title：Clinical rheumatology

authors： Nishimi A,Isozaki T,Nishimi S,Ishii S,Tokunaga T,Furuya H,Wakabayashi K,Kasama T

更新日期：2018-04-01 00:00:00

abstract：:Chronic whiplash-associated disorders (WAD) remains a challenging condition for clinicians. There is substantial evidence for the presence of various cervical dysfunctions (e.g., increased cervical muscle tone and impaired cervical movement control), but their contribution to the complex clinical picture of subjects w...

journal_title：Clinical rheumatology

authors： Nijs J,Van Oosterwijck J,De Hertogh W

更新日期：2009-03-01 00:00:00

abstract：:The objectives of this study are to assess the risk of asymptomatic cranial neuropathy among patients with systemic lupus erythematosus (SLE) and find any association with disease activity and antiribosomal P antibodies. This study is a case-control study including 60 female patients and 30 healthy female controls. Di...

journal_title：Clinical rheumatology

authors： Gaber W,Ezzat Y,El Fayoumy NM,Helmy H,Mohey AM

更新日期：2014-01-01 00:00:00

abstract：:Recurrences of COVID-19 were observed in a patient with long-term usage of hydroxychloroquine, leflunomide, and glucocorticoids due to her 30-year history of rheumatoid arthritis (RA). Tocilizumab was applied and intended to target both COVID-19 and RA. However, disease of this patient aggravated after usage of tocili...

journal_title：Clinical rheumatology

authors： Cai S,Sun W,Li M,Dong L

更新日期：2020-09-01 00:00:00

abstract：:The objective of this study was to identify predictors for remission or low disease activity (LDA) in established rheumatoid arthritis (RA) at 12 months of anti-TNF-α therapy. We have performed a prospective observational study in 90 consecutive patients with active RA receiving TNF-α inhibitors. Baseline and standard...

journal_title：Clinical rheumatology

authors： Pomirleanu C,Ancuta C,Miu S,Chirieac R

更新日期：2013-05-01 00:00:00

abstract：:Disease-modifying antirheumatic biological and non-biological therapies are associated with reduced disease progression and joint destruction. Suggestions have been made that total knee and hip joint arthroplasty indications are decreasing as a beneficial effect of the new forms of therapy for rheumatoid arthritis. We...

journal_title：Clinical rheumatology

authors： De Piano LP,Golmia RP,Scheinberg MA

更新日期：2011-04-01 00:00:00

abstract：:Paediatric systemic lupus erythematosus (pSLE) refers to childhood-onset systemic lupus erythematosus. pSLE has its own unique characteristics, and its pathogenesis is unclear. To study the relationship between microRNAs (miRNAs) and pSLE, we selected three pSLE patients who were newly diagnosed and had not yet been t...

journal_title：Clinical rheumatology

authors： Zhu J,Huang X,Su G,Wang L,Wu F,Zhang T,Song G

更新日期：2014-06-01 00:00:00

abstract：:Our aim is to investigate the effects of three therapeutic approaches in the chronic low back pain on pain, spinal mobility, disability, psychological state, and aerobic capacity. Sixty patients with chronic low back pain were randomized to three groups: group 1, aerobic exercise + home exercise; group 2, physical the...

journal_title：Clinical rheumatology

authors： Koldaş Doğan S,Sonel Tur B,Kurtaiş Y,Atay MB

更新日期：2008-07-01 00:00:00

abstract：:The lactogenic hormone prolactin is produced in part by cells of the immune system and serves as an upregulator of immune function. Hyperprolactinemia is common in patients with systemic lupus erythematosus (SLE), raising the possibility that the hormone contributes to the excessive immune response in the disease. The...

journal_title：Clinical rheumatology

authors： Li M,Keiser HD,Peeva E

更新日期：2006-07-01 00:00:00

abstract：:Atherosclerosis has been shown to be increased in chronic inflammatory diseases including ankylosing spondylitis (AS). Impaired endothelial function, the first step in atherosclerosis, may be reflected by changes in various endothelial biomarkers of hemostasis and the release of several cellular adhesion molecules or ...

journal_title：Clinical rheumatology

authors： Taylan A,Sari I,Kozaci DL,Yildiz Y,Bilge S,Coker I,Maltas S,Gunay N,Akkoc N

更新日期：2012-01-01 00:00:00

abstract：:We report two cases of a full-thickness rotator cuff tear followed by acromioclavicular cyst formation in patients with longstanding erosive polyarticular rheumatoid arthritis. One of the consequences of a rotator cuff tear is articular instability with upward migration of the humeral head. The ensuing chronic frictio...

journal_title：Clinical rheumatology

authors： Selvi E,De Stefano R,Frati E,Manganelli S,Manca S,Marcolongo R

更新日期：1998-01-01 00:00:00

abstract：:The aim of this study is to find out the outcome of 28 patients who got the diagnosis of primary fibromyalgia (pFM) 26 years ago. In 1986, 56 patients with widespread pain were examined and filled in a base questionnaire (BQ). Of them, 42 fulfilled the Yunus criteria for pFM. Twenty-six years later, addresses of 38 pa...

journal_title：Clinical rheumatology

authors： Isomeri R,Mikkelsson M,Partinen M,Kauppi MJ

更新日期：2018-05-01 00:00:00

abstract：:Familial Mediterranean fever (FMF) is prevalent among Arabic, Turkish, Armenian, and Jewish people and it must always be considered in the differential diagnosis of patients from these ethnic groups presenting with recurrent abdominal pain with fever. In cases of fever and recurrent abdominal pain, acute pancreatitis ...

journal_title：Clinical rheumatology

authors： Birlik M,Demir T,Zeybel M,Akar S,Onen F,Comlekci A,Tunca M,Akkoc N

更新日期：2004-12-01 00:00:00

abstract：:To develop and to test in a preliminary way a new self-administered screening tool, called DETection of Arthritis in Inflammatory boweL diseases (DETAIL) questionnaire, in patients suffering from inflammatory bowel disease (IBD) not previously diagnosed as having a spondyloarthritis (SpA). DETAIL questionnaire was rea...

journal_title：Clinical rheumatology

authors： Di Carlo M,Luchetti MM,Benfaremo D,Di Donato E,Mosca P,Maltoni S,Benedetti A,Gabrielli A,Grassi W,Salaffi F

更新日期：2018-04-01 00:00:00

abstract：:We report the case of a 19-year-old woman who consulted for low-back pain 3 weeks after her first delivery. This young woman had a personal history of protein C deficiency and was treated daily during her pregnancy with low-molecular-weight heparin. Her body mass index was 34 and she only gained 10 kg during her pregn...

journal_title：Clinical rheumatology

authors： Goëb V,Strotz V,Verdet M,Le Loët X,Vittecoq O

更新日期：2008-12-01 00:00:00

abstract：:One of the most important therapeutic goal in hyperhidrosis treatment is to seek for the underlying cause and to tailor the treatment accordingly. A detailed history and prompt physical examination are needed to clarify the etiological factor. In this study, we report a 34-year-old woman with a diagnosis of thoracic o...

journal_title：Clinical rheumatology

authors： Ozdemir O,Ozçakar L

更新日期：2007-08-01 00:00:00