Abstract:
:Systemic lupus erythematosus (SLE) has rarely being reported among African Blacks, in contrast with African-Americans. Such reports have been mostly case reports. Our encounter with new cases shows that this disease may not be rare after all. The objective of this study was to study the clinical presentations, laboratory and serological characteristics of Nigerians presenting with SLE. This is part of a retrospective study of patients presenting with rheumatic complaints to a private practice rheumatology clinic, Arthrimed Specialist Clinic located in Lagos, Nigeria. This is a retrospective study of consecutive SLE patients seen in a rheumatology clinic over a 6-year period and diagnosed using the ACR Criteria for SLE. Laboratory tests and serology were carried out when possible. Treatment was initiated with immunosuppressives, steroids, anti epileptics, aspirin and anti hypertensives as indicated. SLE accounted for 5.28% of all the 1,250 rheumatology cases seen over the study period of 6 years. Female constituted 95.5% of the 66 cases seen. The subjects were aged 17-55 with a mean of 33 years at presentation and had the symptoms for a mean of 2.6 years. Polyarthralgia, fever and hair loss were the most common presentation. Neuropsychiatric presentations were common. Erythrocyte sedimentation rate was markedly elevated in most cases. Anti-nuclear antibody titres were markedly high and were mostly speckled staining pattern. Treatment was with conventional immunosuppressives. SLE may not be uncommon among African blacks, contrary to previous reports. A high index of suspicion is needed for this otherwise severe disease in blacks. Early aggressive treatment with immunosuppressives is indicated.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Adelowo OO,Oguntona SAdoi
10.1007/s10067-009-1139-6subject
Has Abstractpub_date
2009-06-01 00:00:00pages
699-703issue
6eissn
0770-3198issn
1434-9949journal_volume
28pub_type
杂志文章abstract::Calcinosis, Raynaud's phenomenon, oesophageal dysmotility, sclerodactyly, telangiectasia (CREST) syndrome, a limited form of systemic sclerosis, is sometimes complicated by primary biliary cirrhosis (PBC). A 52- and 61-year-old Japanese woman with PBC-CREST overlap syndrome accompanied by Sjögren's syndrome, and Hashi...
journal_title:Clinical rheumatology
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doi:10.1007/s10067-005-0178-x
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abstract::Although the Health Assessment Questionnaire (HAQ) and the Modified Health Assessment Questionnaire are useful tools for assessing and monitoring patients with rheumatic diseases, they have a "floor effect" and do not fully reflect the psychological status of patients. Recently, the Multidimensional Health Assessment ...
journal_title:Clinical rheumatology
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更新日期:2006-05-01 00:00:00
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journal_title:Clinical rheumatology
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journal_title:Clinical rheumatology
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journal_title:Clinical rheumatology
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journal_title:Clinical rheumatology
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更新日期:1985-03-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02208694
更新日期:1991-09-01 00:00:00
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更新日期:2021-01-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
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更新日期:2010-09-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-007-0732-9
更新日期:2008-04-01 00:00:00
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journal_title:Clinical rheumatology
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journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
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更新日期:1994-12-01 00:00:00
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journal_title:Clinical rheumatology
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更新日期:1999-01-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2010-04-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-05305-y
更新日期:2020-11-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:
更新日期:1988-12-01 00:00:00
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journal_title:Clinical rheumatology
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journal_title:Clinical rheumatology
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journal_title:Clinical rheumatology
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02230334
更新日期:1996-03-01 00:00:00
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更新日期:2016-07-01 00:00:00
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journal_title:Clinical rheumatology
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更新日期:2007-02-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 杂志文章
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journal_title:Clinical rheumatology
pub_type: 杂志文章
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更新日期:2014-11-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-007-0716-9
更新日期:2008-02-01 00:00:00