Abstract：
:This study investigated the association of combined arthritis and diabetes, diabetes only, and arthritis only compared with neither with gait speed in the general population. This cross-sectional study included data from the second wave of Midlife in the United States-2 (MIDUS 2) project 4: Biomarker Project, 2004-2009. The MIDUS 2 biomarker project included 1255 individuals aged between 34 and 84 years. Participants were categorized into four groups: combined arthritis and diabetes, diabetes only, arthritis only, or neither. The main outcome measure was gait speed measured by the 50-ft walk test. Covariates included age, gender, body mass index (BMI), depression symptoms, and number of chronic conditions/symptoms. A total of 1255 participants were included with mean age 54.52 ± 11.71, of those 713 (56.8%) participants were females. The results showed that combined arthritis and diabetes was significantly associated with a greater decline in gait speed (B = - 0.11, 95% confidence interval (CI) [- 0.17 to - 0.6], p < 0.001). Arthritis and diabetes were independently significantly associated with decreased gait speed (B = - 0.072, 95% CI [- 0.10 to - 0.043], p < 0.001), (B = - 0.064, 95% CI [- 0.12 to - 0.012], p = 0.015), respectively. Combined arthritis and diabetes was associated with a greater decline in gait speed compared with diabetes only, arthritis only, or neither group. Key Points • Combined arthritis and diabetes were associated with declined gait speed. • Gait speed did not differ between people with arthritis compared with people with diabetes. • We recommended including gait speed assessment in regular clinical visits to capture gait speed declines for further health assessments.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Alenazi AM,Alshehri MM,Alqahtani BA,Alanazi AD,Bindawas SMdoi
10.1007/s10067-020-05370-3subject
Has Abstractpub_date
2020-08-27 00:00:00eissn
0770-3198issn
1434-9949pii
10.1007/s10067-020-05370-3pub_type
杂志文章abstract：:Efficacy of hip protector pads to prevent hip fracture is controversial. This study was done to evaluate two comparable groups for fracture risk. Two matched cohorts of long-term care residents in Canada, assessing the efficacy of hip protector pads. Evaluation included demographics, medications/diagnoses, cognition (...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-009-1115-1
更新日期：2009-06-01 00:00:00
abstract：:To develop and to test in a preliminary way a new self-administered screening tool, called DETection of Arthritis in Inflammatory boweL diseases (DETAIL) questionnaire, in patients suffering from inflammatory bowel disease (IBD) not previously diagnosed as having a spondyloarthritis (SpA). DETAIL questionnaire was rea...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3937-6
更新日期：2018-04-01 00:00:00
abstract：:We report a 54 year old female whose successful treatment of cerebral lupus with rituximab was complicated by the development of streptococcus intermedius, on valves damaged by Libman-Sacks endocarditis more than 20 years previously. ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-005-0031-2
更新日期：2006-07-01 00:00:00
abstract：OBJECTIVE:To determine clinical course and outcomes in rheumatic disease patients with coronavirus disease 2019 (COVID-19) and compare results to uninfected patients. METHODS:We conducted a case cohort study of autoimmune disease patients with COVID-19 (confirmed by severe acute respiratory syndrome coronavirus 2 PCR)...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-021-05578-x
更新日期：2021-01-09 00:00:00
abstract：:The aim of our study was to explore the relationship between circulating T cells and ankylosing spondylitis (AS) and to find the role of the CD8+CD122+ T cells in the pathogenesis and progression of AS. With the method of case-control design, flow cytometry was performed to quantitatively determine the percentage of c...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3887-z
更新日期：2018-03-01 00:00:00
abstract：:Vascular endothelial growth factor (VEGF) is known to be involved in the pathogenesis of rheumatoid arthritis (RA). In order to elucidate the association between VEGF levels and RA disease activity, VEGF concentrations were measured in RA patients at different phases and severity levels. Thirty-eight healthy subjects ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-009-1343-4
更新日期：2010-05-01 00:00:00
abstract：BACKGROUND:In antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), central nervous system (CNS) involvement is relatively uncommon. The current study retrospectively investigated the clinical features and outcomes of AAV patients with CNS involvement. METHODS:A total of 497 AAV patients were retrosp...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-020-04975-y
更新日期：2020-07-01 00:00:00
abstract：:Bacteroides fragilis is a rare cause of septic arthritis. Most patients with B. fragilis septic arthritis have a chronic joint disease, particularly rheumatoid arthritis, and sources of infection are lesions of the gastrointestinal tract and the skin. We report a 69-year-old male, who developed B. fragilis septic arth...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02247808
更新日期：1997-11-01 00:00:00
abstract：:Shoulder pain may occur as a secondary symptom to a wide range of conditions, including rotator cuff disorders, glenohumeral osteoarthritis, or adhesive capsulitis. One common factor linking these diseases is inflammation. Understanding the role of inflammation in shoulder disorders can help physicians to manage and t...
journal_title：Clinical rheumatology
pub_type： 杂志文章,收录出版,评审
doi：10.1007/s10067-009-1109-z
更新日期：2009-05-01 00:00:00
abstract：:A 61-year-old female with a history of vaginal dryness, Raynaud's phenomenon, xerostomia and xerophthalmia presented with exertional dyspnoea and weakness. Laboratory and instrumental examinations enabled us to make the diagnosis of primary Sjögren's syndrome, while cardiologic and imaging investigations evidenced iso...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-004-1071-8
更新日期：2005-08-01 00:00:00
abstract：:Disease-modifying antirheumatic biological and non-biological therapies are associated with reduced disease progression and joint destruction. Suggestions have been made that total knee and hip joint arthroplasty indications are decreasing as a beneficial effect of the new forms of therapy for rheumatoid arthritis. We...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-010-1629-6
更新日期：2011-04-01 00:00:00
abstract：:The aim of this study was to determine the emotional and sociodemographic characteristics of patients with ankylosing spondylitis (AS) and to investigate the impact of the disease on their social life and quality of life (QOL). This study included 101 patients with the diagnosis of AS. All patients filled in a questio...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-005-1150-5
更新日期：2006-03-01 00:00:00
abstract：:Joint hypermobility syndrome (JHS) is common in patients presenting to rheumatologists and can cause a range of symptoms leading to physical and psychological distress. Chronic musculoskeletal pain in patients with JHS often responds poorly to analgesics, and a pain management approach may be helpful. Since patients w...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-014-2539-9
更新日期：2014-11-01 00:00:00
abstract：:Autonomic nervous system (ANS) involvement has been studied in systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, Sjogren's syndrome, and ankylosing spondylitis but still has not been studied in psoriatic arthritis (PsA). The aim of this study was to investigate the prevalence and the nature of au...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-013-2239-x
更新日期：2013-07-01 00:00:00
abstract：:A cohort of patients with recently diagnosed axial spondyloarthritis (SpA) was characterized with emphasis on gender differences and factors leading to delay in diagnosis. Clinical, laboratory, and imaging data of 151 consecutive patients diagnosed with ankylosing spondylitis or undifferentiated SpA in 2004-2009 and s...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-011-1719-0
更新日期：2011-08-01 00:00:00
abstract：:To identify clinical variables capable of predicting long-term treatment duration of TNF-α inhibition in patients with Behçet's disease (BD)-related uveitis. Demographic, clinical, and therapeutic data were retrospectively collected from BD patients treated with the tumor necrosis factor (TNF)-α blockers infliximab an...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-018-4092-4
更新日期：2018-06-01 00:00:00
abstract：:Gold salts in vitro modulate lymphocyte proliferation to mitogens and antigens and macrophage phagocytosis. These effects are not confined to gold salts; D-penicillamine and chloroquine as well as some of the non-steroidal anti-inflammatory drugs (NSAIDs) have in vivo immunoregulatory effects. Peripheral blood mononuc...
journal_title：Clinical rheumatology
pub_type： 临床试验,杂志文章
doi：10.1007/BF03342619
更新日期：1984-03-01 00:00:00
abstract：:Ankylosing spondylitis (AS) is associated with an increased risk of atherosclerotic cardiovascular disease (ACD). The atherogenic index of plasma (AIP), which is the logarithmic transformation of the plasma triglyceride (TG) level to the high-density lipoprotein level (HDL) ratio, has been suggested to be a novel mark...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-018-4027-0
更新日期：2018-05-01 00:00:00
abstract：:The ACR/EULAR Boolean remission criteria for rheumatoid arthritis (RA) include a strict cutoff for patient global assessment (PGA, value ≤ 1/10). Near-remission corresponds to remission for joint counts and C-reactive protein but with PGA > 1. The objective was to explore whether the contribution of PGA to remission a...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-018-3998-1
更新日期：2018-06-01 00:00:00
abstract：:With the growing awareness of the impact of chronic back pain and axial spondyloarthritis and recent breakthroughs in genetics and the development of novel treatments which may impact best on early disease, the need for markers that can facilitate early diagnosis and profiling those individuals at the highest risk for...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-015-2949-3
更新日期：2015-06-01 00:00:00
abstract：INTRODUCTION:The prevalence of herpes zoster (HZ) is high in patients with rheumatologic diseases. The incidence in patients with rheumatoid arthritis (RA) is at least twice as high as in healthy people. Nevertheless, little is known about humoral immunity against varicella zoster virus (VZV), in particular in patients...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-019-04563-9
更新日期：2019-09-01 00:00:00
abstract：INTRODUCTION/OBJECTIVES:This study examined whether phase angle (PhA) is associated with hip osteoarthritis (HOA) severity and quadriceps strength in patients with HOA. METHOD:A series of 549 patients with HOA, obtained from the Screening for People Suffering Sarcopenia in the Orthopedic cohort of Kobe study, were ana...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-020-05419-3
更新日期：2020-09-29 00:00:00
abstract：:The objective of this study is to identify baseline factors associated with rheumatoid arthritis (RA) diagnosis at the end of 1-year follow-up in a cohort of patients with very recent onset arthritis. Incident cases with self-reported arthritis ( journal_title：Clinical rheumatology pub_type： 杂志文章 doi：10.1007/s10067-009-1206-z 更新日期：2009-10-01 00:00:00
abstract：:Despite improved quality of care for rheumatoid arthritis (RA) patients, many still experience treatment failure with a biologic agent and eventually switch to another biologic agent. We investigated patterns of biologic treatment and reasons for switching biologics in patients with RA. Patients with RA who had starte...
journal_title：Clinical rheumatology
pub_type： 杂志文章,多中心研究
doi：10.1007/s10067-017-3584-y
更新日期：2017-05-01 00:00:00
abstract：:The effect of long-term (18-70 months) chloroquine treatment 250 mg daily, in rheumatoid arthritis (RA) was studied in 20 patients. Sedimentation rates were significantly reduced, as compared to a reference group of 10 RA patients on no treatment of disease modifying anti-rheumatic drugs. Radiographical progression of...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02041561
更新日期：1983-12-01 00:00:00
abstract：:B cells in patients with rheumatoid arthritis (RA) are hyperactivated. Although B cell receptor signal transduction may be affected by various response regulators, CD22 plays an important role as a response regulator of B cells. Therefore, we investigated and examined CD22 expression on peripheral blood B cells of pat...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-007-0665-3
更新日期：2007-10-01 00:00:00
abstract：:We report a young male with recent onset of rheumatoid arthritis (RA) in whom the remarkable severity of the disease led to additional investigations. The only significant finding was mediastinal lymphadenopathy, without lung involvement. Biopsy of the mediastinal lymph node revealed pathological findings typical of s...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-002-0639-4
更新日期：2003-02-01 00:00:00
abstract：INTRODUCTION:We investigated whether rheumatoid arthritis (RA)-related autoantibodies were associated with abnormalities on pulmonary function tests (PFTs). METHODS:We studied RA serostatus and PFT abnormalities within a RA registry. RA serostatus was assessed by research assays for cyclic citrullinated peptide (CCP) ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-019-04733-9
更新日期：2019-12-01 00:00:00
abstract：:The aim of this study was to investigate the clinical features, risk factors, and outcomes of septic arthritis in patients on maintenance hemodialysis (HD). We systematically reviewed medical records of 16 HD patients with septic arthritis admitted to our hospital from April 2008 to April 2018. A total of 16 HD in pat...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-020-05114-3
更新日期：2020-10-01 00:00:00
abstract：:The original published version of this article contained the incorrect Table 2 and are now presented correctly in this article. ...
journal_title：Clinical rheumatology
pub_type： 杂志文章,已发布勘误
doi：10.1007/s10067-020-04926-7
更新日期：2020-04-01 00:00:00
