Abstract:
:We investigated the occurrence of an active cytomegalovirus (CMV) infection in patients with polyarteritis nodosa (PAN). Eleven patients with PAN were screened for the presence of CMV-DNA in their blood using the polymerase chain reaction (PCR). Serum anti-CMV IgG and anti-CMV IgM antibodies were determined by enzyme-linked immunosorbent assays (ELISA). The ELISA for IgM was negative in all cases whereas that for IgG was positive in eight cases. Only one patient was positive for CMV-DNA by PCR. He presented with myalgia, polyarthralgia, fever and weight loss, suggesting PAN activity. CMV infection was uncommon in our series of patients with PAN, despite disease activity and immunosuppressor therapy. The finding of a transient CMV infection in one case at the beginning of PAN activity suggests that CMV may be involved in the pathogenesis of PAN.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Fernandes SR,Bértolo MB,Rossi CL,Samara AM,Bonon SH,Durante P,Costa SCdoi
10.1007/s100670050148subject
Has Abstractpub_date
1999-01-01 00:00:00pages
501-3issue
6eissn
0770-3198issn
1434-9949journal_volume
18pub_type
杂志文章abstract:BACKGROUND:Sarcoidosis is a chronic inflammatory disease characterized by non-caseating granuloma which etiology is unknown yet. Adipokines are different proteins synthesized by adipose tissue that have an influence on angiogenesis, hemostasis, lipid metabolism, and immune system regulation. Adipokines may play a role ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-04980-1
更新日期:2020-07-01 00:00:00
abstract::Microwave thermography is the technique of measuring natural thermal radiation from body tissues of clinical interest. It is safe, requires no control of environmental conditions and exposes the patient to no ionising radiation. In this study, we found that microwave thermography of the knee joints showed weak correla...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02242999
更新日期:1994-12-01 00:00:00
abstract::The effect of long-term (18-70 months) chloroquine treatment 250 mg daily, in rheumatoid arthritis (RA) was studied in 20 patients. Sedimentation rates were significantly reduced, as compared to a reference group of 10 RA patients on no treatment of disease modifying anti-rheumatic drugs. Radiographical progression of...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02041561
更新日期:1983-12-01 00:00:00
abstract::Clinical guidelines regarding anti-viral prophylaxis for HBV surface antigen (HBsAg) carriers starting anti-TNFα agents are not yet fully established, even in endemic regions of HBV infection. We retrospectively collected the clinical data of 52 HBsAg carriers with rheumatoid arthritis (RA) or ankylosing spondylitis (...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-012-1960-1
更新日期:2012-06-01 00:00:00
abstract::Socio-economic gradients in occurrence of diseases have been reported for many chronic conditions. However, whether the magnitude of socio-economic gradients differs across diseases and the extent to which lifestyle mediates such relationships are not known. Cross-sectional data from The National Monitor on Musculoske...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-018-4158-3
更新日期:2018-12-01 00:00:00
abstract::We report the case of a 19-year-old woman who consulted for low-back pain 3 weeks after her first delivery. This young woman had a personal history of protein C deficiency and was treated daily during her pregnancy with low-molecular-weight heparin. Her body mass index was 34 and she only gained 10 kg during her pregn...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-008-0898-9
更新日期:2008-12-01 00:00:00
abstract::In patients with fibromyalgia (FM) syndrome, stress and pain may chronically enhance sympathetic activity, altering cardiovascular response and inducing endothelial dysfunction. We investigated endothelial function in FM patients using echocardiography and analyzed whether endothelial function was affected by the clin...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-010-1599-8
更新日期:2011-05-01 00:00:00
abstract::Behçet's disease (BD) has well-defined pulmonary complications, but cardiopulmonary exercise testing and the strength of the respiratory muscles have not been studied in detail. We aimed to investigate the pulmonary functions tests, inspiratory and expiratory muscle strength and endurance, cardiopulmonary exercise tes...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-006-0508-7
更新日期:2007-09-01 00:00:00
abstract::The immunoinflammatory pathogenesis of juvenile chronic arthritis (JCA) involves the activation of many pathways including various cytokines. We have evaluated the levels of interleukin(IL)-1, IL-6 and IL-8 in 29 JCA patients. The age range was 1-16 with a mean of 10.1. A disease activity score was developed on the ba...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02247847
更新日期:1997-03-01 00:00:00
abstract::In an open study, we have assessed the bone/soft tissue uptake index in recent osteoporotic vertebral collapse using scintigraphy. The evolution of these cases was followed-up at 6 months in 22 patients treated with 100 IU of salmon calcitonin plus 500 mg of elemental calcium/10 days per month and in 18 patients treat...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02208694
更新日期:1991-09-01 00:00:00
abstract::The swift and accurate diagnosis of acute arterial occlusion and limb ischemia is critical to prevent morbidity from this vascular emergency as reported by Bettman et al. (Radiology 215:101-105, 2000). There are a number of imaging modalities available to the diagnosing physician. However, the most appropriate modalit...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-010-1419-1
更新日期:2013-03-01 00:00:00
abstract::The study aims to analyze the effects of induction treatment with cyclophosphamide (CYC) pulse therapy followed by maintenance treatment with other mild immunosuppressive agents on lung function in scleroderma (SSc) patients. Thirty patients with SSc (mean age 52 years, mean disease duration < 2 years) with forced vit...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-018-4266-0
更新日期:2018-11-01 00:00:00
abstract::Heterogenous population of cells, including macrophages, synoviocytes and lymphocytes play important roles in the immunopathogenesis of rheumatoid arthritis (RA). T cells, however, seem to be a common thread throughout the disease process. In inhibiting T lymphocytes, cyclosporin A presents a more selective form of th...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/BF02215854
更新日期:1995-09-01 00:00:00
abstract::Disease-modifying antirheumatic biological and non-biological therapies are associated with reduced disease progression and joint destruction. Suggestions have been made that total knee and hip joint arthroplasty indications are decreasing as a beneficial effect of the new forms of therapy for rheumatoid arthritis. We...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-010-1629-6
更新日期:2011-04-01 00:00:00
abstract::A pair of identical twins suffering from ankylosing spondylitis is reported. One brother developed an earlier-onset disease and showed ossification of the posterior longitudinal ligament and the flavum ligament in his cervical spine. ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02249033
更新日期:1994-06-01 00:00:00
abstract::We investigated the association between smoking and the disease activity, functional ability, physical mobility, and systemic inflammation in Chinese ankylosing spondylitis (AS) patients. Seventy five male Chinese AS patients in Taiwan were enrolled in the cross-sectional study. These patients fulfilled the 1984 modif...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-013-2165-y
更新日期:2013-05-01 00:00:00
abstract::Clinical characteristics of antitumor necrosis factor (TNF) agents-related tuberculosis (TB) in ankylosing spondylitis (AS) are not well described. The aim was to compare the incidences and the characteristics of TB in AS and rheumatoid arthritis (RA) during TNF inhibitor treatment. AS (n = 1,322) and RA (n = 3,154) p...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-013-2387-z
更新日期:2014-09-01 00:00:00
abstract::Small differences in inbred animals with a gene for arthritis must be the cause that some of them evolve the disease and others not. These differences are partly stochastic, caused by thermal movement of molecules. It is possible that their effect is amplified by a network of cytokines, known to play an important role...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF03342643
更新日期:1996-01-01 00:00:00
abstract::Paediatric systemic lupus erythematosus (pSLE) refers to childhood-onset systemic lupus erythematosus. pSLE has its own unique characteristics, and its pathogenesis is unclear. To study the relationship between microRNAs (miRNAs) and pSLE, we selected three pSLE patients who were newly diagnosed and had not yet been t...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-014-2583-5
更新日期:2014-06-01 00:00:00
abstract::Severe exacerbation of symptoms following physical activity is characteristic for chronic-fatigue syndrome (CFS) and fibromyalgia (FM). These exacerbations make it understandable for people with CFS and FM to develop fear of performing body movement or physical activity and consequently avoidance behaviour toward phys...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-013-2277-4
更新日期:2013-08-01 00:00:00
abstract::The effects of 10 ml of evening primrose oil or olive oil, administered twice daily for 12 weeks, on clinical and laboratory signs and on plasma prostaglandins were studied in 18 patients with rheumatoid arthritis. The plasma concentration of PGE2 decreased and that of TxB2 increased in both treatment groups, but no s...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02030080
更新日期:1989-06-01 00:00:00
abstract::Juvenile idiopathic arthritis (JIA) is the most common chronic arthritis of childhood. Currently, it is characterized by seven categories. The enthesitis-related arthritis (ERA) category usually affects boys older than 6 years and presents with lower limb asymmetrical arthritis associated with enthesitis. Later, these...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-015-3029-4
更新日期:2015-11-01 00:00:00
abstract::This study aims to identify the clinical predictors of arthritis in patients with psoriasis and to evaluate the use of musculoskeletal ultrasonography (US) as a predictor for inflammatory structural progression in psoriatic patients. Measures of association (odds ratio (OR)) were tested, in a prospective, cohort 1-yea...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-014-2630-2
更新日期:2015-02-01 00:00:00
abstract::We compared the short-term effects of Stanger bath therapy and conventional exercises on spinal mobility, functional capacity, disease activity, and quality of life with conventional exercise alone in ankylosing spondylitis (AS) patients. A total of 58 patients with a diagnosis of AS according to the modified New York...
journal_title:Clinical rheumatology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10067-008-0873-5
更新日期:2008-07-01 00:00:00
abstract:INTRODUCTION:Alkaptonuria (AKU) is a rare metabolic disease. The global incidence is 1:100,000 to 1:250,000. However, identification of a founder mutation in a gypsy population from India prompted us to study the prevalence of AKU in this population and to do molecular typing in referred cases of AKU from the rest of I...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-05020-8
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVES:To compare the efficacy and safety of tocilizumab with those of abatacept in patients with active rheumatoid arthritis not responding to anti-tumor necrosis factor therapy. METHODS:A prospective, open-label study was carried out on adult females with moderate-to-severe rheumatoid arthritis. Patients were ra...
journal_title:Clinical rheumatology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10067-019-04508-2
更新日期:2019-08-01 00:00:00
abstract::This study aimed to investigate the multiple values of 18F-FDG PET/CT in detecting malignant tumors, evaluating myopathy, and determining interstitial lung disease in patients with idiopathic inflammatory myopathy (IIM). We retrospectively analyzed the data of 38 patients who were examined by 18F-FDG PET/CT and eventu...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-017-3794-3
更新日期:2017-10-01 00:00:00
abstract::Hepatitis B virus (HBV) reactivation is a common complication of immunosuppressive treatment in high prevalence countries. Biological disease-modifying antirheumatic drugs (bDMARDs) cause this adverse event more often than conventional immunosuppressants. The incidence of HBV reactivation during treatment for rheumati...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-018-4295-8
更新日期:2018-11-01 00:00:00
abstract::Systemic sclerosis (SS) alters smooth muscle function throughout the gastrointestinal tract, the oesophagus being the segment most often involved. Involvement of the colon, though less common, may lead to life-threatening complications. We studied 23 unselected patients with SS and 20 age-matched healthy controls usin...
journal_title:Clinical rheumatology
pub_type: 临床试验,杂志文章
doi:10.1007/s100670170038
更新日期:2001-01-01 00:00:00
abstract::The authors of the published version of this article incorrectly presented the affiliation of Li-Chin Sung. The revised affiliation is now presented correctly in this article. ...
journal_title:Clinical rheumatology
pub_type: 杂志文章,已发布勘误
doi:10.1007/s10067-019-04531-3
更新日期:2019-05-01 00:00:00