Mechanism of action of cyclosporin in rheumatoid arthritis.

abstract：:The levels of 63 cytokines, chemokines, and growth factors were measured in the serum of four patients with idiopathic morphea and of one patient with vitamin K1-induced morphea employing a multiplex assay to identify the role of inflammatory/immunologic events in their pathogenesis. Full-thickness skin biopsies of af...

journal_title：Clinical rheumatology

authors： Cox LA,Webster GF,Piera-Velazquez S,Jimenez SA

更新日期：2017-05-01 00:00:00

abstract：:Anti-nucleosome antibodies, which recognise conformational epitopes consisting of histone and DNA in chromatin, have been described in autoimmune diseases. In this study, an attempt was made to isolate anti-nucleosome antibodies from the anti-DNA-depleted plasma IgG of two lupus patients either with or without nephrit...

journal_title：Clinical rheumatology

authors： Suenaga R,Mitamura K,Abdou NI

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to evaluate the interrelationship between the micro- and macrovasculature. METHODS:This is a cross-sectional study that examined SSc patients and fibromyalgia (FM) patients as controls. We assessed forearm peripheral vascular status and nailfold capillaroscopy. We evaluated the assoc...

journal_title：Clinical rheumatology

authors： Bieber A,Dolnikov K,Chizik V,Novofastovsky I,Fawaz A,Balbir-Gurman A,Mader R

更新日期：2020-09-01 00:00:00

abstract：:Total body bone mineral (TBBM) measured by dual photon absorptiometry and local bone mineral (BMC) measured by single photon absorptiometry were determined in 55 patients with definite or classical rheumatoid arthritis. All of them had been on a steady dose of anti-inflammatory drugs for at least 12 months, and furthe...

journal_title：Clinical rheumatology

authors： Skibsted Als O,Gotfredsen A,Christiansen C

更新日期：1983-09-01 00:00:00

abstract：:In a Sidonian sarcophagus, from the Late Antique/early Christian period, skeletal remains of two persons were found. One of them, male, 30-50 years old, was found almost completely ankylosed, with highly osteoporotic bones and prominent erosion of joint surfaces. We diagnosed rheumatoid arthritis based on the eroded o...

journal_title：Clinical rheumatology

authors： Bašić Ž,Jerković I,Kružić I,Anđelinović Š

更新日期：2017-01-01 00:00:00

abstract：:Inflammation of one or both sacroiliac joints is a characteristic feature of patients with spondyloarthropathies (SpA). Sacroiliitis often leads to inflammatory back pain (IBP). IBP and asymmetric peripheral arthritis of the lower limbs are the main clinical symptoms and criteria for classification and diagnosis of Sp...

journal_title：Clinical rheumatology

authors： Braun J,Sieper J,Bollow M

更新日期：2000-01-01 00:00:00

abstract：:This pilot study aimed to evaluate the correlation between clinical symptoms and cartilage volume through MRI in patients with knee osteoarthritis after 48 weeks of treatment with Structum®. Multicenter, double-blind, placebo-controlled, parallel-group study. Symptomatic knee osteoarthritis patients aged 50-75 years r...

journal_title：Clinical rheumatology

authors： Railhac JJ,Zaim M,Saurel AS,Vial J,Fournie B

更新日期：2012-09-01 00:00:00

abstract：:The burden of anxiety in patients with systemic lupus erythematosus (SLE) compared to those with other inflammatory rheumatological conditions is unclear. We aimed to compare the frequency and level of anxiety between patients with SLE, rheumatoid arthritis (RA), and gout and healthy individuals and explore independen...

journal_title：Clinical rheumatology

authors： Mak A,Tang CS,Chan MF,Cheak AA,Ho RC

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVES:(1) Development and validation of a composite ultrasound score (cUSS) for the diagnosis of carpal tunnel syndrome (CTS). (2) To predict treatment response after local corticosteroid injection. METHODS:Wrists of CTS patients and controls were evaluated with high-resolution ultrasound and cross-sectional area...

journal_title：Clinical rheumatology

authors： Goswami RP,Sit H,Chatterjee M,Lahiri D,Sircar G,Ghosh P

更新日期：2020-07-21 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is a complex autoimmune disorder that affects various organs and systems. Increased apoptosis, together with defects in the uptake of apoptotic bodies, are thought to have a pathogenic role in SLE. By detection of chromatin condensation, 30% of apoptosis was detected in peripheral bl...

journal_title：Clinical rheumatology

authors： Pitidhammabhorn D,Kantachuvesiri S,Totemchokchyakarn K,Kitiyanant Y,Ubol S

更新日期：2006-09-01 00:00:00

abstract：:We investigated some steps in the signal transduction pathway leading to the proliferation of synovial cells. 12-o-tetradecanoyl phorbol-13-acetate (TPA) which is known to stimulate phospholipid- and Ca(2+)-dependent protein kinase (C-kinase) enhanced the proliferation of synovial cells. The proliferation of synovial ...

journal_title：Clinical rheumatology

authors： Yamamoto M,Yasuda M,Shiokawa S,Nobunaga M

更新日期：1992-03-01 00:00:00

abstract：:The aim of this study was to determine whether the prolactin -1149 G/T polymorphism confers susceptibility to systemic lupus erythematous (SLE) and rheumatoid arthritis (RA). A meta-analysis was conducted for examining the associations between prolactin -1149 G/T polymorphism and susceptibility to SLE or RA using alle...

journal_title：Clinical rheumatology

authors： Lee YH,Bae SC,Song GG

更新日期：2015-04-01 00:00:00

abstract：:Increased IFN-γ levels have been associated with systemic lupus erythematosus (SLE). However, the relationships among IFN-γ, type I interferons (IFNs) and clinical features have not been extensively studied. Peripheral blood samples from 44 SLE patients and 36 healthy donors (HDs) were collected. Quantitative real-tim...

journal_title：Clinical rheumatology

authors： Liu M,Liu J,Hao S,Wu P,Zhang X,Xiao Y,Jiang G,Huang X

更新日期：2018-10-01 00:00:00

abstract：:We describe the case of a 26-year-old African female who was treated successfully with belimumab in a case of severe membranous lupus nephritis and retinal vasculitis, resistant to first line therapy. She presented initially with chronic dacryoadenitis and screening showed nephrotic-range proteinuria. Biopsy of the ki...

journal_title：Clinical rheumatology

authors： De Scheerder MA,Boey O,Mahieu E,Vanuytsel J,Bogaert AM

更新日期：2016-06-01 00:00:00

abstract：:In juvenile chronic arthritis (JCA) the indices of disease activity, such as joint swelling, pain, tenderness, and limitation of motion, may poorly correlate with the degree of functional impairment. Since the improvement of functional capacity is one of the main objectives of treatment, we evaluated the effect of met...

journal_title：Clinical rheumatology

authors： Ravelli A,Viola S,Ramenghi B,Di Fuccia G,Ruperto N,Zonta L,Martini A

更新日期：1995-05-01 00:00:00

abstract：:Hundreds of randomized controlled trials (RCTs) on tripterygium glycosides tablet (TGT) in the treatment of ankylosing spondylitis (AS) have been published, but the therapeutic effects have never been systematically reviewed yet. The aim of this meta-analysis was to evaluate the efficacy of TGT on AS based on RCTs. Pu...

journal_title：Clinical rheumatology

authors： Li H,Guo F,Luo YC,Zhu JP,Wang JL

更新日期：2015-11-01 00:00:00

abstract：:In 1960 Rabinowitz and Dameshek emphasized the close relationship between idiopathic thrombocytopenic purpura (ITP) and systemic lupus erythematosus (SLE) and suggested that ITP is often a prodrome of SLE. On the basis of tis observation, the present study was designed to investigate the prevalence of SLE in patients ...

journal_title：Clinical rheumatology

authors： Lavalle C,Hurtado R,Quezada JJ,Cabral A,Fraga A

更新日期：1983-09-01 00:00:00

abstract：:Antibodies to 65Kd heat-shock protein (hsp) of mycobacterium leprae were measured by enzyme-linked immunosorbent assay (ELISA) in the three immunoglobulin classes in paired sera and synovial fluids of patients with rheumatoid arthritis (RA). Titers of anti-hsp antibody were expressed by optical density (OD) values for...

journal_title：Clinical rheumatology

authors： Oda A,Miyata M,Kodama E,Satoh H,Sato Y,Nishimaki T,Nomaguchi H,Kasukawa R

更新日期：1994-06-01 00:00:00

abstract：:In the last 5 years, several hundred articles have been published concerning the link between primary immunodeficiency disease (PID) and rheumatologic diseases. Although rheumatologic complications were originally thought to be at the opposite ends of the spectrum of immunopathologic manifestations, they are now all b...

journal_title：Clinical rheumatology

authors： Dimitriades VR,Sorensen R

更新日期：2016-04-01 00:00:00

abstract：:Reactive arthritis (ReA) due to Gram-negative intestinal bacteria or Chlamydia, is associated by an unknown mechanism with HLA-B27. Like other MHC class I molecules, HLA-B27 presents antigenic peptides derived from intracellular proteins to CD8+ cytotoxic T cells (CTL). In humans however, CTL specific for ReA associat...

journal_title：Clinical rheumatology

authors： Ringrose JH,Yard BA,Verjans GM,Boog CJ

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:Gout is a common inflammatory disease, and the prevalence of gout in men is significantly higher than in women. Catechol-O-methyltransferase (COMT) regulates dopamine activity and metabolism, thereby participating in the uric acid metabolism, which in turn affects the occurrence of gout. Our study aimed to in...

journal_title：Clinical rheumatology

authors： Ying X,Chen Y,Zheng Z,Duan S

更新日期：2019-10-01 00:00:00

abstract：:This study demonstrates whether serum β2-microglobulin (β2-MG) level can be an indicator of the status of systemic lupus erythematosus (SLE) and adult-onset Still's disease (AOSD), and development of hemophagocytic syndrome (HPS) complication. Serum β2-MG level was compared between the active and inactive statuses of ...

journal_title：Clinical rheumatology

authors： Wakabayashi K,Inokuma S,Matsubara E,Onishi K,Asashima H,Nakachi S,Hagiwara K

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:To evaluate and compare the diagnostic test accuracy of magnetic resonance imaging (MRI) and ultrasound (US) for bone erosion in rheumatoid arthritis (RA) patients for a specific and efficient diagnostic recommendation. METHOD:To evaluate the diagnostic accuracy, the sensitivity, specificity, area under the ...

journal_title：Clinical rheumatology

authors： Tang H,Qu X,Yue B

更新日期：2020-04-01 00:00:00

abstract：:A patient fulfilling the diagnostic criteria for systemic lupus erythematosus and presenting with catatonic schizophrenia is described. Psychiatric features of the disease and their management are discussed. ...

journal_title：Clinical rheumatology

authors： Tishler M,Abramov AL

更新日期：1985-09-01 00:00:00

abstract：:To measure serum soluble transferrin receptor (s-TfR) levels in patients with rheumatoid arthritis (RA), sera were obtained from 50 Japanese RA patients and 20 healthy subjects. Both s-TfR and serum erythropoietin (EPO) levels were measured by enzyme-linked immunosorbent assay (ELISA). Routine laboratory tests were al...

journal_title：Clinical rheumatology

authors： Chijiwa T,Nishiya K,Hashimoto K

更新日期：2001-01-01 00:00:00

abstract：:Behcet's disease (BD) is a systemic vasculitis characterized by genital and oral ulcers, uveitis, and other organs' involvement. Left ventricular (LV) diastolic dysfunction has been documented in BD. However, conventional echocardiographic techniques have serious limitations like its dependence on preload, afterload a...

journal_title：Clinical rheumatology

authors： Baris N,Okan T,Gurler O,Akdeniz B,Turker S,Ilknur T,Akkoc N,Goldeli O

更新日期：2006-11-01 00:00:00

abstract：INTRODUCTION:Interleukin-1 receptor-associated kinases (IRAKs) are serine-threonine kinases involved in toll-like receptor and interleukin-1 signaling pathways. They play a key role in inflammation and innate immunity. IRAKs have been previously incriminated in autoimmune diseases such as systemic lupus erythematosus (...

journal_title：Clinical rheumatology

authors： Boumiza A,Zemni R,Sghiri R,Idriss N,Hassine HB,Chabchoub E,Mzabi A,Ghannouchi N,Bouajina E,Ben Hadj Slama F

更新日期：2020-02-01 00:00:00

abstract：:Children with juvenile idiopathic arthritis (JIA) may infrequently present with localized anterior knee pain or swelling, in addition to generalize knee pain induced by JIA. We report five cases of deep infrapatellar bursitis in children with JIA. The clinical features, radiological findings, management, and outcome o...

journal_title：Clinical rheumatology

authors： Alqanatish JT,Petty RE,Houghton KM,Guzman J,Tucker LB,Cabral DA,Cairns RA

更新日期：2011-02-01 00:00:00

abstract：:A 73-year-old patient, whose hip was completely destroyed by pigmented villonodular synovitis, was successfully treated by a total prosthetic replacement of this articulation. The etiopathogenesis of the illness is uncertain. Its' localization in the hip is, fortunately, a rare occurrence. It can be responsible for fr...

journal_title：Clinical rheumatology

authors： Descamps F,Yasik E,Hardy D,Lafontaine M,Delince P

更新日期：1991-06-01 00:00:00

abstract：:2'5'-Oligoadenylate synthetase (OAS) was shown to be related to systemic lupus erythematosus (SLE) 20 years ago, and was rediscovered to be involved in type I interferon pathway in SLE by several microarray gene expression studies recently. The goal of this study was to investigate OAS isoform expressions in lupus pat...

journal_title：Clinical rheumatology

authors： Ye S,Guo Q,Tang JP,Yang CD,Shen N,Chen SL

更新日期：2007-02-01 00:00:00