Abstract:
:In the last 5 years, several hundred articles have been published concerning the link between primary immunodeficiency disease (PID) and rheumatologic diseases. Although rheumatologic complications were originally thought to be at the opposite ends of the spectrum of immunopathologic manifestations, they are now all being considered secondary manifestations of a causative primary "immune derangement." For the rheumatologist, it is important to be able to identify patients who may present with typical rheumatologic findings but who have an underlying PID. In a systematic manner, this overview addresses both the systemic and organ-based rheumatologic diseases which have known associations with primary immunodeficiencies, and explores how immunodeficiency may actually cause these clinical manifestations.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Dimitriades VR,Sorensen Rdoi
10.1007/s10067-016-3229-6subject
Has Abstractpub_date
2016-04-01 00:00:00pages
843-50issue
4eissn
0770-3198issn
1434-9949pii
10.1007/s10067-016-3229-6journal_volume
35pub_type
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