Rheumatologic manifestations of primary immunodeficiency diseases.

Abstract:

:In the last 5 years, several hundred articles have been published concerning the link between primary immunodeficiency disease (PID) and rheumatologic diseases. Although rheumatologic complications were originally thought to be at the opposite ends of the spectrum of immunopathologic manifestations, they are now all being considered secondary manifestations of a causative primary "immune derangement." For the rheumatologist, it is important to be able to identify patients who may present with typical rheumatologic findings but who have an underlying PID. In a systematic manner, this overview addresses both the systemic and organ-based rheumatologic diseases which have known associations with primary immunodeficiencies, and explores how immunodeficiency may actually cause these clinical manifestations.

journal_name

Clin Rheumatol

journal_title

Clinical rheumatology

authors

Dimitriades VR,Sorensen R

doi

10.1007/s10067-016-3229-6

subject

Has Abstract

pub_date

2016-04-01 00:00:00

pages

843-50

issue

4

eissn

0770-3198

issn

1434-9949

pii

10.1007/s10067-016-3229-6

journal_volume

35

pub_type

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