Colonic transit disorders in systemic sclerosis.

Abstract:

:Systemic sclerosis (SS) alters smooth muscle function throughout the gastrointestinal tract, the oesophagus being the segment most often involved. Involvement of the colon, though less common, may lead to life-threatening complications. We studied 23 unselected patients with SS and 20 age-matched healthy controls using radionuclide colon transit studies. The geometric centre (GC) at 4 and 24 hours was used to summarise overall transit in the colon. In patients with SS, colon transit was delayed (GC4: 0.39 +/- 0.36 vs 0.85 +/- 0.45; P=0.001) (GC24: 1.68 +/- 0.9 vs 2.58 +/- 1.08; P=0.006). These findings suggest that delayed colon transit is common in patients with SS.

journal_name

Clin Rheumatol

journal_title

Clinical rheumatology

authors

Wang SJ,Lan JL,Chen DY,Chen YH,Hsieh TY,Lin WY

doi

10.1007/s100670170038

subject

Has Abstract

pub_date

2001-01-01 00:00:00

pages

251-4

issue

4

eissn

0770-3198

issn

1434-9949

journal_volume

20

pub_type

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