Abstract:
:The coexistence of polymyositis (PM) and primary biliary cirrhosis (PBC) is rare; only nine cases have been described in English literature. We report a case of a 46-year-old woman presenting with these two autoimmune diseases. The diagnosis of PM was based on the symmetrical, proximal limb muscle weakness, elevated muscle enzymes and was confirmed with the electromyography and muscle biopsy. The diagnosis of PBC was based on the increased serum levels of alkaline phosphatase, gamma glutamyltransferase, IgM immunoglobulin, the presence of antimitochondrial antibodies and diagnostic liver biopsy.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Boki KA,Dourakis SPdoi
10.1007/BF02208358subject
Has Abstractpub_date
1995-05-01 00:00:00pages
375-8issue
3eissn
0770-3198issn
1434-9949journal_volume
14pub_type
杂志文章abstract::The involvement of brain-derived neurotrophic factor (BDNF) in rheumatoid arthritis (RA) is largely unknown. The distribution of BDNF and its associated receptors, TrkB and p75, in the synovial tissue of patients with RA was examined and contrasted with that in patients with osteoarthritis (OA). Additionally, levels o...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-008-0910-4
更新日期:2008-10-01 00:00:00
abstract:OBJECTIVE:Anti-cyclic citrullinated peptide 2 antibodies (anti-CCP2) and rheumatoid factor (RF) in rheumatoid arthritis (RA) has been extensively assessed in industrialized countries. We investigated the diagnostic and prognostic impact of anti-CCP2 and RF isotypes in a Sudanese cross-sectional RA cohort. METHODS:Cons...
journal_title:Clinical rheumatology
pub_type: 杂志文章,多中心研究
doi:10.1007/s10067-019-04431-6
更新日期:2019-06-01 00:00:00
abstract::One hundred and twenty patients with hemisacralization of the L5 vertebra associated with LBP underwent clinical, conventional X-ray and CT examinations. More than 50% of the patients had scoliosis. One third of the patients had disc lesions. Sacroiliac joint sclerosis was noted in two thirds of the cases. Almost all ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02054251
更新日期:1986-09-01 00:00:00
abstract::The signalling lymphocyte activation molecule (SLAM) family receptors play important roles in modulating immune responses. Previous studies in murine models and patients have suggested an association of the SLAM family (SLAMF) members with the development of autoimmunity, particularly systemic lupus erythematosus (SLE...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-017-3698-2
更新日期:2018-03-01 00:00:00
abstract::Fragile X mental retardation 1 (FMR1) premutation carriers, who are at risk of having children with fragile X Syndrome, were initially considered as clinically unaffected. However, recent clinical and molecular studies have shifted this point of view. The incidence of premutation in the general population is substanti...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-012-2052-y
更新日期:2012-11-01 00:00:00
abstract::Four patients with rheumatoid nodulosis are here described, together with a review of cases reported to date in the literature. This particular variant of rheumatoid arthritis (RA) is characterized by the presence of subcutaneous rheumatoid nodules, scanty or absent systemic manifestations and a clinically benign cour...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02207201
更新日期:1992-09-01 00:00:00
abstract::Evidence for Chagas disease reactivation (CDR) in rheumatologic patients under rheumatologic treatments (RTs) is scarce. To screen and follow-up patients with rheumatic diseases and concomitant Chagas disease under RT to detect CDR and to describe a possible relationship between CDR and specific RT. An observational, ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-021-05581-2
更新日期:2021-01-12 00:00:00
abstract:OBJECTIVES:This study was conducted to assess the safety and efficacy of intra-articular injection of etanercept and compare it with corticosteroid injection in rheumatoid arthritis (RA) patients. METHODS:Fifty patients with RA who suffered from activity in one joint were randomized into two groups, received an intra-...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-05235-9
更新日期:2021-02-01 00:00:00
abstract:BACKGROUND:Sarcoidosis is a chronic inflammatory disease characterized by non-caseating granuloma which etiology is unknown yet. Adipokines are different proteins synthesized by adipose tissue that have an influence on angiogenesis, hemostasis, lipid metabolism, and immune system regulation. Adipokines may play a role ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-04980-1
更新日期:2020-07-01 00:00:00
abstract::The aim of the study was to present a method enabling a reduction of the number of measurements when quantifying isokinetic muscle strength (IMS), and to describe an expression for IMS which is independent of measuring conditions. IMS is a measure of muscle strength used to categorise patients and to assess changes ov...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/pl00011211
更新日期:2001-01-01 00:00:00
abstract::Behçet's disease is a multisystem disorder affecting the skin, mucous membranes, eye, joints, central nervous system, and blood vessels. One of the known vascular complications of Behçet's disease is venous thrombosis or aneurysm formation. We report, herewith, a patient with Behçet's disease who developed radial arte...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02229654
更新日期:1996-09-01 00:00:00
abstract::Although a number of reports have now described an association between polymorphism of the LMP2 gene and disease phenotype in HLA-B27 positive individuals with ankylosing spondylitis (AS), some describe associations with acute anterior uveitis, others with juvenile onset disease, and one report provides no association...
journal_title:Clinical rheumatology
pub_type: 临床试验,杂志文章
doi:10.1007/BF02238938
更新日期:1997-09-01 00:00:00
abstract::Either total hip arthroplasty (THA), total knee arthroplasty (TKA) or both were performed in 105 patients from 1981 to 1994. These patients were experiencing severe joint destruction in the lower extremities due to rheumatoid arthritis (RA). These patients were followed for more than 2 years after their last operation...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF01452259
更新日期:1998-01-01 00:00:00
abstract:INTRODUCTION:Idiopathic granulomatous mastitis (IGM) is a rare, chronic inflammatory benign breast disease. Although the etiology of this disease is unknown, it has been suggested that hormonal disorders, autoimmunity, smoking, and α1-antitrypsin deficiency may play a role in the etiopathogenesis. The aim is to investi...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-04925-8
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:To determine clinical course and outcomes in rheumatic disease patients with coronavirus disease 2019 (COVID-19) and compare results to uninfected patients. METHODS:We conducted a case cohort study of autoimmune disease patients with COVID-19 (confirmed by severe acute respiratory syndrome coronavirus 2 PCR)...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-021-05578-x
更新日期:2021-01-09 00:00:00
abstract::The idiopathic inflammatory myopathies (IIM) constitute a subset of autoimmune conditions primarily affecting muscle, along with many extra-muscular manifestations. Proximal muscle weakness is the dominant symptom in the IIM. In addition, many patients will have cutaneous manifestations, pulmonary manifestations, and ...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-015-2891-4
更新日期:2015-05-01 00:00:00
abstract::Systemic sclerosis (SSc) is an autoimmune disease which may lead to malnutrition. Previous studies have defined it with different criteria. No thorough evaluations of sarcopenia in SSc are available. The aim of the present study was to assess the prevalence and the potential association of malnutrition and sarcopenia ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-017-3932-y
更新日期:2018-04-01 00:00:00
abstract::The aim of this study was to identify and evaluate laboratory parameters associated with normal bone mineral density (BMD) and to test if -308 tumour necrosis factor (TNF) alpha gene promoter polymorphisms could influence BMD. We performed a comparative cross-sectional study of four main groups: young healthy individu...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-007-0706-y
更新日期:2008-03-01 00:00:00
abstract::Sustained cough is a frequent complaint in methotrexate (MTX) treatment for rheumatoid arthritis and can be a symptom of incipient MTX-induced pneumonitis. This study was performed to characterize MTX-associated cough clinically and to clarify by which means this condition can be distinguished from incipient MTX pneum...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02229707
更新日期:1996-05-01 00:00:00
abstract::This study aims to evaluate the impact of arthritis on the physical function of people living in a Maya-Yucateco rural community and to assess the association of known modifiable risk factors with the prevalence of overall arthritis and its main types (osteoarthritis and rheumatoid arthritis). Using a cross-sectional,...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-015-3084-x
更新日期:2016-07-01 00:00:00
abstract::Spondylodiscitis may be either infectious or rheumatic in origin. In the latter case it may be seen more often in the context of spondyloarthropathies, giving rise to inflammatory back pain. We report the case of a man, affected by ulcerative colitis and carcinoma of the colon, who developed spondylodiscitis due to in...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s100670170011
更新日期:2001-01-01 00:00:00
abstract::Biologic therapies have brought improved efficacy in the field of rheumatoid arthritis (RA), but their use in clinical practice may be limited by concerns over cost. Predictive models are, therefore, needed to identify those people with RA with the worst potential outcomes, who will benefit most from the use of these ...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-010-1639-4
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVE:Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) are rare small to medium-size vessel systemic diseases. As their clinical picture, organ involvement, and factors influencing outcome may differ between countries and geographical areas, we decided to describe a large cohort of Polish AA...
journal_title:Clinical rheumatology
pub_type: 杂志文章,多中心研究
doi:10.1007/s10067-019-04538-w
更新日期:2019-09-01 00:00:00
abstract::The aims of our study are to observe the pregnancy outcome of anti-Sjögren's syndrome-related antigen A (SSA)/Ro-positive women and to predict the risk factors for adverse pregnancy outcome and neonatal lupus erythematosus (NLE). Clinical data of 126 anti-SSA/Ro-positive patients with 140 pregnancies were evaluated re...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-015-3050-7
更新日期:2015-10-01 00:00:00
abstract::Rheumatoid arthritis (RA) is a progressive inflammatory disease. Although the etiology and pathogenesis of RA are not known well, genetic and environmental factors are proposed to initiate an autoimmune process. We aimed to investigate mRNA expression levels of Toll-like receptor-2 (TLR-2), TLR-4, and interleukin-6 (I...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-016-3282-1
更新日期:2016-11-01 00:00:00
abstract::We reported a series of ten patients with lupus nephritis (five patients in the relapse phase and five in the remission phase) and measured the macrophage migration inhibitory factor (MIF), an important pro-inflammatory cytokine with probable role in the pathogenesis of many inflammatory diseases, in their urine sampl...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-007-0632-z
更新日期:2007-12-01 00:00:00
abstract::Streptococcus is well associated with a myriad of inflammatory diseases. Among others, this bacterium is linked to the triggering of psoriasis and to post-streptococcal reactive arthritis (PSRA), an arthritis which is typically confined to peripheral joints. Three patients who developed acute psoriatic spondyloarthrit...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-019-04695-y
更新日期:2019-09-01 00:00:00
abstract::There is an increasing concern over generalizability of trial results. We investigated eligibility criteria of knee osteoarthritis clinical trials. Eligible trials were randomized, placebo-controlled trials that were identified by searches in MEDLINE, SCOPUS, and the Cochrane Central Register of Controlled Trials. We ...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-013-2342-z
更新日期:2013-11-01 00:00:00
abstract::We present a patient with previously diagnosed hypocomplementemic urticarial vasculitis syndrome, with skin, lung, and renal involvement, who presented with congestive cardiac failure. During the course of her hospitalization, she was also found to have profound proximal muscle weakness in both upper and lower limbs a...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-006-0397-9
更新日期:2007-08-01 00:00:00
abstract::To examine the relationship between physical appearance concern and psychological distress in female adolescent patients with systemic lupus erythematosus (SLE) was the aim of this study. A total of 84 adolescent SLE female patients and 80 age-matching healthy adolescents were evaluated for levels of appearance concer...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-012-2071-8
更新日期:2012-12-01 00:00:00