Polymyositis associated with primary biliary cirrhosis.


:The coexistence of polymyositis (PM) and primary biliary cirrhosis (PBC) is rare; only nine cases have been described in English literature. We report a case of a 46-year-old woman presenting with these two autoimmune diseases. The diagnosis of PM was based on the symmetrical, proximal limb muscle weakness, elevated muscle enzymes and was confirmed with the electromyography and muscle biopsy. The diagnosis of PBC was based on the increased serum levels of alkaline phosphatase, gamma glutamyltransferase, IgM immunoglobulin, the presence of antimitochondrial antibodies and diagnostic liver biopsy.


Clin Rheumatol


Clinical rheumatology


Boki KA,Dourakis SP




Has Abstract


1995-05-01 00:00:00












  • Adult onset Still's disease diagnosed concomitantly with occult papillary thyroid cancer: paraneoplastic manifestation or coincidence?

    abstract::Adult onset Still's disease (AOSD) is an inflammatory disease of unknown etiology, characterized by spiking fever, evanescent salmon pink maculopapular rash, arthritis, and leukocytosis with neutrophilia. Malignant lymphoma is one of the most important differential diagnoses of AOSD. AOSD has been reported as one of p...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Ahn JK,Oh JM,Lee J,Kim SW,Cha HS,Koh EM

    更新日期:2010-02-01 00:00:00

  • Multiple avascular necrosis in a patient with systemic lupus erythematosus/systemic sclerosis overlap syndrome.

    abstract::A white female patient developed overlapping features of systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) with severe pulmonary compromise. She was treated with steroids and azathioprine, which improved her clinical condition and spirometric status. In May 2002 she presented with continuous pain in her ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Cavallasca JA,Laborde HA,Araujo MB,Nasswetter GG

    更新日期:2005-08-01 00:00:00

  • Differences in clinical Pneumocystis pneumonia in rheumatoid arthritis and other connective tissue diseases suggesting a rheumatoid-specific interstitial lung injury spectrum.

    abstract::To compare Pneumocystis pneumonia (PCP) in patients with rheumatoid arthritis (RA) with PCP in patients with non-RA connective tissue diseases (CTDs) in order to clarify the characteristics of the former. We extracted consecutive patients satisfying the following criteria for "clinical PCP": (1) positive plasma β-D-gl...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Shimada K,Yokosuka K,Nunokawa T,Sugii S

    更新日期:2018-08-01 00:00:00

  • Cellular localization of the Ro/SS-A antigen.

    abstract::The cellular localization of the Ro/SS-A antigen was defined using indirect immunofluorescence and eight monospecific anti- Ro/SS-A antisera which were identified by immunoblotting. Several mammalian tissues were used as substrates. The Ro/SS-A antigen was located mainly in the nucleus of dog liver and Hep-2-cells, an...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Lopez-Robles E,Herrera-Esparza R,Avalos-Diaz E

    更新日期:1986-01-01 00:00:00

  • Bone mass in Zaireans: radiogrammetric determination.

    abstract::Bone mass was measured in 230 subjects with ages ranging from 15 to 54 years (110 males and 120 females), using the radiogrammetric method on the second metacarpal bone. Results of the study show that bone mass increases with age up to 34 years and then decreases, both in males and females, although males have signifi...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Kabeya JM,Mbuyi Muamba JM,Tozin R,Dequeker J

    更新日期:1995-01-01 00:00:00

  • Investigations concerning vitamin A transport in rheumatic diseases.

    abstract::The investigation concerned changes in vitamin A derivatives (retinol and retinyl) content in serum of patients suffering from two types of rheumatic diseases--rheumatoid arthritis (RA) and osteoarthrosis. Healthy women of similar age served as control. It was found that the retinol content of the serum in the group s...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Mezes M,Bartosiewicz B

    更新日期:1982-09-01 00:00:00

  • Mycophenolate mofetil in Takayasu's arteritis.

    abstract::Mycophenolate mofetil (MMf) has recently been reported as a useful alternative immunosuppressive drug in autoimmune diseases. There is paucity of literature on its use in Takayasu's arteritis (TA). The aim of this study was to assess the safety and efficacy of MMf in Asian Indian patients with Takayasu's arteritis. Re...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Goel R,Danda D,Mathew J,Edwin N

    更新日期:2010-03-01 00:00:00

  • Progress made towards enhancement of rheumatology education and practice in Zambia: review of an ILAR-supported project.

    abstract::The burden of non-communicable diseases such as musculoskeletal diseases in the developing world is often overshadowed by the more prevalent infectious diseases. Generally, there is gross underestimation of the burden of rheumatologic disease in the backdrop of scanty or indeed non-existent rheumatology services in th...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,评审


    authors: Chipeta J,Njobvu P,McGill PE,Bucala R

    更新日期:2014-01-01 00:00:00

  • GITRL is associated with increased autoantibody production in patients with rheumatoid arthritis.

    abstract::The study aimed to determine the serum level of glucocorticoid-induced tumor necrosis factor receptor family-related protein ligand (GITRL) in patients with rheumatoid arthritis (RA) and investigate its clinical significance. GITRL levels were measured by enzyme-linked immunosorbent assay (ELISA) in 88 RA patients, 20...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Li L,Wen W,Jia R,Li Y,Liu X,Sun X,Li Z

    更新日期:2016-09-01 00:00:00

  • Humoral immunity to varicella zoster virus is altered in patients with rheumatoid arthritis.

    abstract:INTRODUCTION:The prevalence of herpes zoster (HZ) is high in patients with rheumatologic diseases. The incidence in patients with rheumatoid arthritis (RA) is at least twice as high as in healthy people. Nevertheless, little is known about humoral immunity against varicella zoster virus (VZV), in particular in patients...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Krasselt M,Baerwald C,Liebert UG,Seifert O

    更新日期:2019-09-01 00:00:00

  • Circulating intercellular adhesion molecule 1 in rheumatoid arthritis--relationship to systemic vasculitis and microvascular injury in nailfold capillary microscopy.

    abstract::Intercellular adhesion molecule-1 (ICAM-1) is a membrane bound molecule that plays an important role in the pathogenic inflammatory responses observed in vasculitis. The aim of this study was to determine whether levels of soluble ICAM-1 sICAM-1) shedding into the circulation reflect the vascular injury found in nailf...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Kuryliszyn-Moskal A,Bernacka K,Klimiuk PA

    更新日期:1996-07-01 00:00:00

  • Acute phase proteins and clinical synovitis activity in patients with rheumatoid arthritis.

    abstract::A number of laboratory variables, including Hb., ESR and several phase proteins, fluctuated in concord with the clinical signs of synovitis activity in patients with rheumatoid arthritis during a controlled study of 3 disease-modifying anti-rheumatic drugs (DMARD). The correlation between laboratory variables and clin...

    journal_title:Clinical rheumatology

    pub_type: 临床试验,杂志文章


    authors: Bentzon MW,Gad I,Halberg P,Halskov O,Lorenzen I

    更新日期:1987-06-01 00:00:00

  • Ten-year progression of coronary artery, carotid artery, and aortic calcification in patients with rheumatoid arthritis.

    abstract::Rheumatoid arthritis (RA) is associated with increased vascular calcification, although the rate of progress of calcification is uncertain. The aim of the study was to evaluate the progression of and the predictors for calcification in different vascular beds over 10 years. The 10-year actual coronary calcium score (C...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Liu JH,Ng MY,Cheung T,Chung HY,Chen Y,Zhen Z,Zou Y,Mak KF,Khong PL,Lau CS,Tse HF,Yiu KH

    更新日期:2017-04-01 00:00:00

  • Prevalence of IgA class antibodies to cyclic citrullinated peptide (anti-CCP) in patients with primary Sjögren's syndrome, and its association to clinical manifestations.

    abstract::This study aims to determine the prevalence and clinical significance of anti-CCP isotype IgA in a population of patients with primary Sjögren's syndrome (pSS). Sixty-two patients diagnosed according to the USA-European classification criteria for pSS were examined two to four times during a 60.4-month follow-up, and ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Haga HJ,Andersen DT,Peen E

    更新日期:2011-03-01 00:00:00

  • Hyperimmunoglobulinemia D syndrome in an Arab child.

    abstract::Hyperimmunoglobulinemia D syndrome (HIDS) is newly recognized and resembles familial Mediterranean fever (FMF). It is inherited as an autosomal recessive trait. Mutation of the gene coding for mevalonate kinase is responsible for the disease. The gene is located at chromosome 12q24. The patients initially described we...

    journal_title:Clinical rheumatology

    pub_type: 信件


    authors: Hammoudeh M

    更新日期:2005-02-01 00:00:00

  • The clinical value of measuring immunoglobulins when assessing penicillamine therapy in rheumatoid arthritis.

    abstract::Immunoglobulins are often high in active rheumatoid arthritis and fall when treatment with a slow-acting anti-rheumatic drug is instituted. We assessed the value of monitoring immunoglobulins during penicillamine therapy; 145 patients were followed for up to 5 years, IgA, IgM and IgG levels were compared to 12 other c...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Williams A,Scott DL,Greenwood A,Huskisson EC

    更新日期:1988-09-01 00:00:00

  • Reactivity of pulmonary circulation and right ventricle function to inhaled nitric oxide in systemic sclerosis patients.

    abstract::Systemic sclerosis (SSc) is complicated by pulmonary hypertension and right ventricle (RV) failure in approximately 10% of the patients. Factors influencing the reactivity of pulmonary circulation to vasodilators are not established, while the examination of vasoreactivity is important in determining the treatment, be...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Plazak W,Gryga K,Sznajd J,Wilisowska J,Czarnobilska E,Goncerz G,Podolec P,Musial J

    更新日期:2012-01-01 00:00:00

  • From scleredema to AL amyloidosis: disease progression or coincidence? Review of the literature.

    abstract::Scleredema (also called scleredema of Buschke) is a fibromucinous connective tissue disorder of unknown cause that belongs to a group of scleroderma-like disorders. We report the case of a 64-year-old lady with long-standing scleredema, associated with a paraprotein, and progressing to multiple myeloma and AL amyloido...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,评审


    authors: Dziadzio M,Anastassiades CP,Hawkins PN,Potter M,Gabrielli A,Brough GM,Black CM,Denton CP

    更新日期:2006-02-01 00:00:00

  • Thrombocytopenia in patients with rheumatoid arthritis on long-term treatment with low dose methotrexate.

    abstract::We reviewed the records of 315 patients with rheumatoid arthritis (RA) treated with low-dose methotrexate (MTX) and evaluated the conditions contributing to thrombocytopenia. Thirteen out of 315 patients with RA presented with low platelet counts (< or = 100.000/mm3). The age of these patients (51 +/- 12.6 years) did ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Franck H,Rau R,Herborn G

    更新日期:1996-03-01 00:00:00

  • Implication of invalidation concept in fibromyalgia diagnosis.

    abstract:OBJECTIVES:The invalidation or social pain is an important but neglected issue in polysymptomatology of fibromyalgia (FM). This study sought whether tracing-perceived invalidation could be effective to discriminate between the presence and absence of FM in chronic pain patients with respect to five different sources, i...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Ghavidel-Parsa B,Bidari A,Tohidi S,Shenavar I,Kazemnezhad Leyli E,Hosseini K,Khosousi MJ

    更新日期:2021-01-07 00:00:00

  • Clinical features, risk factors, and outcomes of septic arthritis in patients on maintenance hemodialysis.

    abstract::The aim of this study was to investigate the clinical features, risk factors, and outcomes of septic arthritis in patients on maintenance hemodialysis (HD). We systematically reviewed medical records of 16 HD patients with septic arthritis admitted to our hospital from April 2008 to April 2018. A total of 16 HD in pat...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Zhang J,You X

    更新日期:2020-10-01 00:00:00

  • High-titer antichromatin antibody is associated with proliferative class IV of lupus nephritis.

    abstract::The antichromatin antibody (aCT) has been described as a useful marker for lupus nephropathy. The relevance of its nephritogenic potential may be appropriately evaluated in the context of renal histopathology. Therefore, the present study investigated the relationship of aCT with a particular histopathologic class of ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Carvalho JF,Viana VS,Borba EF,do Nascimento AP,Leon EP,Testagrossa LA,Barros RT,Bonfá E

    更新日期:2008-11-01 00:00:00

  • Predictors of activity limitation in people with gout: a prospective study.

    abstract::The objective of the study was to determine clinical factors associated with activity limitation and predictors of a change in activity limitation after 1 year in people with gout. Two hundred ninety-five participants with gout (disease duration < 10 years) attended a baseline assessment which included medical and dis...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Stewart S,Rome K,Eason A,House ME,Horne A,Doyle AJ,Knight J,Taylor WJ,Dalbeth N

    更新日期:2018-08-01 00:00:00

  • The use of low-dose naltrexone (LDN) as a novel anti-inflammatory treatment for chronic pain.

    abstract::Low-dose naltrexone (LDN) has been demonstrated to reduce symptom severity in conditions such as fibromyalgia, Crohn's disease, multiple sclerosis, and complex regional pain syndrome. We review the evidence that LDN may operate as a novel anti-inflammatory agent in the central nervous system, via action on microglial ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,评审


    authors: Younger J,Parkitny L,McLain D

    更新日期:2014-04-01 00:00:00

  • Outcome of late-onset rheumatoid arthritis.

    abstract::The objective of this study was to determine possible differences in the outcome of patients with rheumatoid arthritis (RA) with disease onset early and late in life. As part of a broader outcome study of RA which included patients seen in the division of Rheumatology of Hospital Universitario Marqués de Valdecilla of...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Calvo-Alén J,Corrales A,Sánchez-Andrada S,Fernández-Echevarría MA,Peña JL,Rodríguez-Valverde V

    更新日期:2005-09-01 00:00:00

  • A 'made in one piece' skeleton in a 22-year-old man suffering from sickle cell anaemia.

    abstract::A 22-year-old African male with known sickle cell anaemia was referred by a Congolese medical centre with a request to improve his poor physical condition. He was unable to walk, stand or sit because his large joints and his spine were either ankylosed or very rigid. Radiographs showed joint fusion from the third to t...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Dumarey N,Martin P,Jayankura M,Putz P,Verhas M,Peretz A

    更新日期:2000-01-01 00:00:00

  • Clinical characteristics of autoimmune rheumatic disease-related organizing pneumonia.

    abstract::To study the clinical characteristics of autoimmune rheumatic disease-related organizing pneumonia (AIRD-OP), the clinical presentation, radiological findings, treatment, and outcome of AIRD-OP patients were analyzed, in comparison with patients with cryptogenic organizing pneumonia (COP). A total of 131 OP patients w...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Dong X,Zheng Y,Wang L,Chen WH,Zhang YG,Fu Q

    更新日期:2018-04-01 00:00:00

  • FDG PET/CT used in identifying adult-onset Still's disease in connective tissue diseases.

    abstract:PURPOSE:To explore the 18F-fluoro-dexoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) imaging characteristics of adult-onset Still's disease (AOSD) and its significance in differential diagnosis from other connective tissue diseases (CTDs). METHODS:FDG PET/CT images of 54 patients with AOSD...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Zhou X,Li Y,Wang Q

    更新日期:2020-09-01 00:00:00

  • Elevated interleukin-18 levels correlated with disease activity in systemic lupus erythematosus.

    abstract::The aim of this study was to determine the serum interleukin-18 (IL-18) levels in patients with systemic lupus erythematosus (SLE) and to assess their relationship with disease activity. Thirty-five patients with SLE and 35 age- and sex-matched controls were enrolled in this study. Paired serum samples were collected ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Park MC,Park YB,Lee SK

    更新日期:2004-06-01 00:00:00

  • Chronic eosinophilic pneumonia associated with an initiation of rheumatoid arthritis.

    abstract::Although peripheral blood eosinophilia is observed in patients with active inflammatory rheumatoid arthritis (RA), RA is not a recognised cause of pulmonary eosinophilia. We describe a 55-year-old woman affected by chronic eosinophilic pneumonia (CEP) concomitantly with an initiation of RA. Both diseases responded rap...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Kwak JJ,Chang JE,Lee J,Cho YJ,Sung SH

    更新日期:2003-09-01 00:00:00