Polymyositis associated with primary biliary cirrhosis.


:The coexistence of polymyositis (PM) and primary biliary cirrhosis (PBC) is rare; only nine cases have been described in English literature. We report a case of a 46-year-old woman presenting with these two autoimmune diseases. The diagnosis of PM was based on the symmetrical, proximal limb muscle weakness, elevated muscle enzymes and was confirmed with the electromyography and muscle biopsy. The diagnosis of PBC was based on the increased serum levels of alkaline phosphatase, gamma glutamyltransferase, IgM immunoglobulin, the presence of antimitochondrial antibodies and diagnostic liver biopsy.


Clin Rheumatol


Clinical rheumatology


Boki KA,Dourakis SP




Has Abstract


1995-05-01 00:00:00












  • Aggressive and atypical manifestations of Erdheim-Chester disease.

    abstract::Erdheim-Chester disease (ECD) is a disseminated non-Langerhans' cell histiocytosis with multisystem involvement, including characteristic sclerotic musculoskeletal lesions. We present the case of a 27-year-old woman with a fulminant course and atypical involvement by ECD manifesting as extensive cerebrovascular diseas...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Lyders EM,Kaushik S,Perez-Berenguer J,Henry DA

    更新日期:2003-12-01 00:00:00

  • Efficacy of tocilizumab in a patient with refractory psoriatic arthritis.

    abstract::Psoriatic arthritis (PsA) is an inflammatory arthropathy, associated with skin and/or nail psoriasis and other possible systemic features. In the last years, PsA therapy has been revolutionized by the increasing knowledge in the pathogenetic mechanisms of the disease, involving dysfunction and oversecretion of multipl...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Costa L,Caso F,Cantarini L,Del Puente A,Scarpa R,Atteno M

    更新日期:2014-09-01 00:00:00

  • Long-term performance in vitro and in vivo of dual-energy X-ray absorptiometry.

    abstract::Dual-energy X-ray absorptiometry (DXA) is actually considered as one of the most appropriate techniques for measuring bone mineral content (BMC) and bone mineral density (BMD). An anthropomorphic phantom and a 25-year-old girl were repeatedly measured, 160 times and 50 times respectively, over an 18-month period to in...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Reginster JY,Deroisy R,Zegels B,Jupsin I,Albert A,Franchimont P

    更新日期:1995-03-01 00:00:00

  • Pain management today - what have we learned?

    abstract::Pain is a leading cause of morbidity worldwide, with published data showing its prevalence as high as 50% for chronic pain in the European population. This prevalence is likely to continue to rise, particularly in elderly people with comorbid conditions and complex aetiologies of pain. There is thus a rapidly growing ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,评审


    authors: Langford RM

    更新日期:2006-01-01 00:00:00

  • Partial construction of apoptotic pathway in PBMC obtained from active SLE patients and the significance of plasma TNF-alpha on this pathway.

    abstract::Systemic lupus erythematosus (SLE) is a complex autoimmune disorder that affects various organs and systems. Increased apoptosis, together with defects in the uptake of apoptotic bodies, are thought to have a pathogenic role in SLE. By detection of chromatin condensation, 30% of apoptosis was detected in peripheral bl...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Pitidhammabhorn D,Kantachuvesiri S,Totemchokchyakarn K,Kitiyanant Y,Ubol S

    更新日期:2006-09-01 00:00:00

  • Better effect of methotrexate on C-reactive protein during daily compared to weekly treatment in rheumatoid arthritis.

    abstract::Treatment with methotrexate (MTX) is well established in rheumatoid arthritis (RA), but dosing remains arbitrary as studies on the effect of different dosing schedules are lacking. In a randomised crossover design of 20 patients with RA, the effect of low (2.5mg) oral daily doses of MTX (15 mg weekly) was compared to ...

    journal_title:Clinical rheumatology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Seideman P

    更新日期:1993-06-01 00:00:00

  • Effect of thymidylate synthase (TYMS) gene polymorphisms with methotrexate treatment outcome in south Indian Tamil patients with rheumatoid arthritis.

    abstract::Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease causing joint damage and significant functional impairment. Methotrexate (MTX) remains the mainstay for the treatment of RA. MTX inhibits several enzymes of the folate and nucleotide pathways. Thymidylate synthase (TYMS) is an important enzyme in the d...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Muralidharan N,Misra DP,Jain VK,Negi VS

    更新日期:2017-06-01 00:00:00

  • Treatment of osteoporosis in renal insufficiency.

    abstract::Patients with osteoporosis often have chronic kidney disease (CKD). CKD is associated with bone and mineral disturbances, renal osteodystrophy, which like osteoporosis leads to a higher risk of fractures. Bisphosphonates are first-line therapy for osteoporosis; however, these are contra-indicated in patients with a GF...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,评审


    authors: Schipper LG,Fleuren HW,van den Bergh JP,Meinardi JR,Veldman BA,Kramers C

    更新日期:2015-08-01 00:00:00

  • Implication of invalidation concept in fibromyalgia diagnosis.

    abstract:OBJECTIVES:The invalidation or social pain is an important but neglected issue in polysymptomatology of fibromyalgia (FM). This study sought whether tracing-perceived invalidation could be effective to discriminate between the presence and absence of FM in chronic pain patients with respect to five different sources, i...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Ghavidel-Parsa B,Bidari A,Tohidi S,Shenavar I,Kazemnezhad Leyli E,Hosseini K,Khosousi MJ

    更新日期:2021-01-07 00:00:00

  • Long-term effects of immunosuppressive therapy on lung function in scleroderma patients.

    abstract::The study aims to analyze the effects of induction treatment with cyclophosphamide (CYC) pulse therapy followed by maintenance treatment with other mild immunosuppressive agents on lung function in scleroderma (SSc) patients. Thirty patients with SSc (mean age 52 years, mean disease duration < 2 years) with forced vit...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Pavlov-Dolijanovic S,Vujasinovic Stupar N,Zugic V,Ostojic P,Zekovic A,Zivanovic Radnic T,Jeremic I,Tadic I

    更新日期:2018-11-01 00:00:00

  • Cardiovascular events prediction by left ventricular longitudinal strain and serum high-sensitivity troponin I in patients with axial spondyloarthritis.

    abstract:OBJECTIVE:Patients with axial spondyloarthritis (SpA) are subjected to elevated cardiovascular risks, but assessment of early myocardial damage and clinical risk stratification remained obscure. The aim of this study was to evaluate the prognostic value of speckle-tracking strain analysis and serum high-sensitivity tro...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Chen Y,Chan YH,Chung HY,Wu MZ,Yu YJ,Pi KL,Lau CS,Tse HF,Yiu KH

    更新日期:2020-11-01 00:00:00

  • Interactions and perceptions of patients with rheumatoid arthritis participating in an online support group.

    abstract:OBJECTIVE:Peer support is important for psychosocial well-being in patients with rheumatoid arthritis (RA). Our objective was to assess the interactions, engagement, and perceptions of participants in an online support group for patients with RA. METHODS:Participants were 18 years or older, diagnosed with RA within 10...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: des Bordes JKA,Foreman J,Westrich-Robertson T,Lopez-Olivo MA,Peterson SK,Hofstetter C,Lyddiatt A,Willcockson I,Leong A,Suarez-Almazor ME

    更新日期:2020-06-01 00:00:00

  • Pattern of systemic lupus erythematosus among Nigerians.

    abstract::Systemic lupus erythematosus (SLE) has rarely being reported among African Blacks, in contrast with African-Americans. Such reports have been mostly case reports. Our encounter with new cases shows that this disease may not be rare after all. The objective of this study was to study the clinical presentations, laborat...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Adelowo OO,Oguntona SA

    更新日期:2009-06-01 00:00:00

  • Potential risk factors for reactive arthritis and persistence of symptoms at 2 years: a case-control study with longitudinal follow-up.

    abstract::The objective of the study is to determine the risk factors for the development of reactive arthritis (ReA) and examine the factors associated with the persistence of symptoms. Patients with a new diagnosis of ReA and controls with a gastrointestinal (GI), urogenital, or sexually transmitted infection in the 3-6 month...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Garcia Ferrer HR,Azan A,Iraheta I,Von Feldt J,Espinoza LR,Manasson J,Scher JU,Garcia Kutzbach A,Ogdie A

    更新日期:2018-02-01 00:00:00

  • The importance of vitamin C for hydroxylation of vitamin D3 to 1,25(OH)2D3 in man.

    abstract::The effects of vitamin C on 1,25(OH)2D3 synthesis in humans were evaluated; the study included 20 females. They were divided into 2 groups. The first of the 10 subjects (age range 55-71) received ascorbic acid at a dose of 150 mg/die i.v. for 10 days; the second 10 subjects (age range 55-69) received a placebo i.v. fo...

    journal_title:Clinical rheumatology

    pub_type: 临床试验,杂志文章


    authors: Cantatore FP,Loperfido MC,Magli DM,Mancini L,Carrozzo M

    更新日期:1991-06-01 00:00:00

  • The value of bone scintigraphy in the follow-up of vertebral osteoporosis.

    abstract::In an open study, we have assessed the bone/soft tissue uptake index in recent osteoporotic vertebral collapse using scintigraphy. The evolution of these cases was followed-up at 6 months in 22 patients treated with 100 IU of salmon calcitonin plus 500 mg of elemental calcium/10 days per month and in 18 patients treat...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Rico H,Merono E,Del Olmo J,Revilla M

    更新日期:1991-09-01 00:00:00

  • Median time to low disease activity is shorter in tocilizumab combination therapy with csDMARDs as compared to tocilizumab monotherapy in patients with active rheumatoid arthritis and inadequate responses to csDMARDs and/or TNF inhibitors: sub-analysis of

    abstract::To analyse efficacy and safety of tocilizumab in patients with rheumatoid arthritis (RA) and an inadequate response to conventional synthetic disease-modifying anti-rheumatic drugs (csDMARDs) and/or tumour necrosis factor (TNF) inhibitors of the Swiss and Austrian patients from the ACT-SURE study. This is a sub-analys...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Mueller RB,Graninger W,Sidiropoulos P,Goger C,von Kempis J

    更新日期:2017-10-01 00:00:00

  • Differences in clinical Pneumocystis pneumonia in rheumatoid arthritis and other connective tissue diseases suggesting a rheumatoid-specific interstitial lung injury spectrum.

    abstract::To compare Pneumocystis pneumonia (PCP) in patients with rheumatoid arthritis (RA) with PCP in patients with non-RA connective tissue diseases (CTDs) in order to clarify the characteristics of the former. We extracted consecutive patients satisfying the following criteria for "clinical PCP": (1) positive plasma β-D-gl...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Shimada K,Yokosuka K,Nunokawa T,Sugii S

    更新日期:2018-08-01 00:00:00

  • Impact of TNF-α inhibitor on lipid profile and atherogenic index of plasma in axial spondyloarthritis: 2-year follow-up data from the Catholic Axial Spondyloarthritis COhort (CASCO).

    abstract::To evaluate the influence of TNF-α inhibitor on lipid profile and atherogenic index of plasma (AIP) in axial spondyloarthritis (axSpA) patients with long-term use of stable dose TNF-α inhibitor. AxSpA patients were enrolled in the Catholic Axial Spondyloarthritis COhort (CASCO). We collected their data annually and an...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Min HK,Lee J,Ju JH,Park SH,Kwok SK

    更新日期:2020-02-01 00:00:00

  • Imaging of the seronegative anterior chest wall (ACW) syndromes.

    abstract::The sternocostoclavicular (SCC) region is subject to the same diseases that occur in joints, with congenital and developmental anomalies, inflammatory and infectious diseases, soft tissue and bone tumors as well as the seronegative spondyloarthropathies, including ankylosing spondylitis, reactive arthritis, enteropath...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,评审


    authors: Guglielmi G,Scalzo G,Cascavilla A,Salaffi F,Grassi W

    更新日期:2008-07-01 00:00:00

  • A comparison of prednisolone with azathioprine and prednisolone with intramuscular gold in rheumatoid arthritis.

    abstract::Pulse prednisolone hemisuccinate therapy (500 mg given intravenously on three occasions over two weeks) has been combined with either intramuscular sodium aurothiomalate or azathioprine in an assessment of 30 patients with rheumatoid arthritis. Significant improvement in a variety of clinical and biochemical assessmen...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Häntzschel H,Otto W,Arnold S,Seidel W,Krüger W,Winiecki P,Bird HA,Dixon JS,Astbury G,Wright V

    更新日期:1988-06-01 00:00:00

  • An unusual case of autoimmune hepatitis in a patient with adult-onset Still's disease.

    abstract::Adult-onset Still's disease (AOSD) is an autoimmune disease characterized by spiking fever, evanescent rash, arthritis, serositis, and liver involvement. Although autoimmune hepatitis (AIH) has been reported in association with various autoimmune diseases, AOSD-associated AIH is rare. We herein report an unusual case ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Xia LX,Xiao T

    更新日期:2010-01-01 00:00:00

  • Additional effect of pulsed electromagnetic field therapy on knee osteoarthritis treatment: a randomized, placebo-controlled study.

    abstract::The aim of this study was to evaluate if pulsed electromagnetic field therapy (PEMF) has additional effect on the classical physical treatment of knee osteoarthritis (OA) composed of hot pack, therapeutic ultrasound, and terminal isometric exercises. Forty patients (29 women and 11 men), ages 44 to 78 (mean age was 61...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,随机对照试验


    authors: Ozgüçlü E,Cetin A,Cetin M,Calp E

    更新日期:2010-08-01 00:00:00

  • Comparison of 8-year knee osteoarthritis progression in 2 siblings: a case-based review.

    abstract::Because the pathophysiology of knee osteoarthritis is poorly understood, optimal evidence-based clinical management is uncertain. Sibling comparison studies can help inform a clinical model to guide preventive care. We compared the 8-year clinical outcomes in 2 sisters with a family history of osteoarthritis, normal B...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,评审


    authors: Gourlay ML,Gourlay LL

    更新日期:2020-10-01 00:00:00

  • Myelodysplastic and myeloproliferative syndromes associated with giant cell arteritis and polymyalgia rheumatica: a coincidental coexistence or a causal relationship?

    abstract::A variety of systemic autoimmune disorders have been reported in patients with myelodysplastic and myeloproliferative syndromes. A possible association with polymyalgia rheumatica and giant cell arteritis has also been recognised. We report another case of polymyalgia rheumatica and one of giant cell arteritis associa...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Espinosa G,Font J,Muñoz-Rodríguez FJ,Cervera R,Ingelmo M

    更新日期:2002-08-01 00:00:00

  • Occurrence of anti-CCP2 and RF isotypes and their relation to age and disease severity among Sudanese patients with rheumatoid arthritis.

    abstract:OBJECTIVE:Anti-cyclic citrullinated peptide 2 antibodies (anti-CCP2) and rheumatoid factor (RF) in rheumatoid arthritis (RA) has been extensively assessed in industrialized countries. We investigated the diagnostic and prognostic impact of anti-CCP2 and RF isotypes in a Sudanese cross-sectional RA cohort. METHODS:Cons...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,多中心研究


    authors: Elshafie AI,Elbagir S,Aledrissy MIE,Elagib EM,Nur MAM,Rönnelid J

    更新日期:2019-06-01 00:00:00

  • Rate and causes of noncompliance with disease-modifying antirheumatic drug regimens in patients with rheumatoid arthritis.

    abstract:INTRODUCTION/OBJECTIVES:To determine the prevalence and factors associated with medication noncompliance by Thai patients with rheumatoid arthritis (RA). METHODS:This prospective cohort study enrolled 443 adult RA patients (≥ 18 years) who were followed up at the outpatient rheumatology clinics of Siriraj Hospital and...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Katchamart W,Narongroeknawin P,Sukprasert N,Chanapai W,Srisomnuek A

    更新日期:2020-09-21 00:00:00

  • Syndrome of periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) in siblings.

    abstract::PFAPA syndrome is characterized by episodes of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis. PFAPA syndrome usually begins in children under 5 years old and normally has self-resolution. The etiology of PFAPA syndrome remains unknown. In this paper, we report the cases of two different famil...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Valenzuela PM,Majerson D,Tapia JL,Talesnik E

    更新日期:2009-10-01 00:00:00

  • Improving management of musculoskeletal disorders in primary care: the Joint Adventures Program.

    abstract::Musculoskeletal disorders represent a large and growing clinical challenge to primary care clinicians. Unfortunately, there appears to be a gap in current training and continuing education to meet this challenge. We used script concordance within a continuing medical education program entitled "Joint Adventures" to as...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Petrella RJ,Davis P

    更新日期:2007-07-01 00:00:00

  • Comparison of effectiveness and safety of infliximab, etanercept, and adalimumab in psoriatic arthritis patients who experienced an inadequate response to previous disease-modifying antirheumatic drugs.

    abstract::The aim of this study is to compare effectiveness and safety of Infliximab (INF), Etanercept (ETN), and Adalimumab (ADA) in patients with psoriatic arthritis (PsA) with inadequate response to a previous disease-modifying antirheumatic drug (DMARD). One hundred consecutive PsA patients with inadequate response to a pre...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,随机对照试验


    authors: Atteno M,Peluso R,Costa L,Padula S,Iervolino S,Caso F,Sanduzzi A,Lubrano E,Del Puente A,Scarpa R

    更新日期:2010-04-01 00:00:00