Abstract:
:The coexistence of polymyositis (PM) and primary biliary cirrhosis (PBC) is rare; only nine cases have been described in English literature. We report a case of a 46-year-old woman presenting with these two autoimmune diseases. The diagnosis of PM was based on the symmetrical, proximal limb muscle weakness, elevated muscle enzymes and was confirmed with the electromyography and muscle biopsy. The diagnosis of PBC was based on the increased serum levels of alkaline phosphatase, gamma glutamyltransferase, IgM immunoglobulin, the presence of antimitochondrial antibodies and diagnostic liver biopsy.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Boki KA,Dourakis SPdoi
10.1007/BF02208358subject
Has Abstractpub_date
1995-05-01 00:00:00pages
375-8issue
3eissn
0770-3198issn
1434-9949journal_volume
14pub_type
杂志文章abstract::Adult onset Still's disease (AOSD) is an inflammatory disease of unknown etiology, characterized by spiking fever, evanescent salmon pink maculopapular rash, arthritis, and leukocytosis with neutrophilia. Malignant lymphoma is one of the most important differential diagnoses of AOSD. AOSD has been reported as one of p...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-009-1305-x
更新日期:2010-02-01 00:00:00
abstract::A white female patient developed overlapping features of systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) with severe pulmonary compromise. She was treated with steroids and azathioprine, which improved her clinical condition and spirometric status. In May 2002 she presented with continuous pain in her ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-004-1048-7
更新日期:2005-08-01 00:00:00
abstract::To compare Pneumocystis pneumonia (PCP) in patients with rheumatoid arthritis (RA) with PCP in patients with non-RA connective tissue diseases (CTDs) in order to clarify the characteristics of the former. We extracted consecutive patients satisfying the following criteria for "clinical PCP": (1) positive plasma β-D-gl...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-018-4157-4
更新日期:2018-08-01 00:00:00
abstract::The cellular localization of the Ro/SS-A antigen was defined using indirect immunofluorescence and eight monospecific anti- Ro/SS-A antisera which were identified by immunoblotting. Several mammalian tissues were used as substrates. The Ro/SS-A antigen was located mainly in the nucleus of dog liver and Hep-2-cells, an...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02030965
更新日期:1986-01-01 00:00:00
abstract::Bone mass was measured in 230 subjects with ages ranging from 15 to 54 years (110 males and 120 females), using the radiogrammetric method on the second metacarpal bone. Results of the study show that bone mass increases with age up to 34 years and then decreases, both in males and females, although males have signifi...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02208090
更新日期:1995-01-01 00:00:00
abstract::The investigation concerned changes in vitamin A derivatives (retinol and retinyl) content in serum of patients suffering from two types of rheumatic diseases--rheumatoid arthritis (RA) and osteoarthrosis. Healthy women of similar age served as control. It was found that the retinol content of the serum in the group s...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02042773
更新日期:1982-09-01 00:00:00
abstract::Mycophenolate mofetil (MMf) has recently been reported as a useful alternative immunosuppressive drug in autoimmune diseases. There is paucity of literature on its use in Takayasu's arteritis (TA). The aim of this study was to assess the safety and efficacy of MMf in Asian Indian patients with Takayasu's arteritis. Re...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-009-1333-6
更新日期:2010-03-01 00:00:00
abstract::The burden of non-communicable diseases such as musculoskeletal diseases in the developing world is often overshadowed by the more prevalent infectious diseases. Generally, there is gross underestimation of the burden of rheumatologic disease in the backdrop of scanty or indeed non-existent rheumatology services in th...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-014-2624-0
更新日期:2014-01-01 00:00:00
abstract::The study aimed to determine the serum level of glucocorticoid-induced tumor necrosis factor receptor family-related protein ligand (GITRL) in patients with rheumatoid arthritis (RA) and investigate its clinical significance. GITRL levels were measured by enzyme-linked immunosorbent assay (ELISA) in 88 RA patients, 20...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-016-3280-3
更新日期:2016-09-01 00:00:00
abstract:INTRODUCTION:The prevalence of herpes zoster (HZ) is high in patients with rheumatologic diseases. The incidence in patients with rheumatoid arthritis (RA) is at least twice as high as in healthy people. Nevertheless, little is known about humoral immunity against varicella zoster virus (VZV), in particular in patients...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-019-04563-9
更新日期:2019-09-01 00:00:00
abstract::Intercellular adhesion molecule-1 (ICAM-1) is a membrane bound molecule that plays an important role in the pathogenic inflammatory responses observed in vasculitis. The aim of this study was to determine whether levels of soluble ICAM-1 sICAM-1) shedding into the circulation reflect the vascular injury found in nailf...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02230359
更新日期:1996-07-01 00:00:00
abstract::A number of laboratory variables, including Hb., ESR and several phase proteins, fluctuated in concord with the clinical signs of synovitis activity in patients with rheumatoid arthritis during a controlled study of 3 disease-modifying anti-rheumatic drugs (DMARD). The correlation between laboratory variables and clin...
journal_title:Clinical rheumatology
pub_type: 临床试验,杂志文章
doi:10.1007/BF02201028
更新日期:1987-06-01 00:00:00
abstract::Rheumatoid arthritis (RA) is associated with increased vascular calcification, although the rate of progress of calcification is uncertain. The aim of the study was to evaluate the progression of and the predictors for calcification in different vascular beds over 10 years. The 10-year actual coronary calcium score (C...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-016-3536-y
更新日期:2017-04-01 00:00:00
abstract::This study aims to determine the prevalence and clinical significance of anti-CCP isotype IgA in a population of patients with primary Sjögren's syndrome (pSS). Sixty-two patients diagnosed according to the USA-European classification criteria for pSS were examined two to four times during a 60.4-month follow-up, and ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-010-1675-0
更新日期:2011-03-01 00:00:00
abstract::Hyperimmunoglobulinemia D syndrome (HIDS) is newly recognized and resembles familial Mediterranean fever (FMF). It is inherited as an autosomal recessive trait. Mutation of the gene coding for mevalonate kinase is responsible for the disease. The gene is located at chromosome 12q24. The patients initially described we...
journal_title:Clinical rheumatology
pub_type: 信件
doi:10.1007/s10067-004-0953-0
更新日期:2005-02-01 00:00:00
abstract::Immunoglobulins are often high in active rheumatoid arthritis and fall when treatment with a slow-acting anti-rheumatic drug is instituted. We assessed the value of monitoring immunoglobulins during penicillamine therapy; 145 patients were followed for up to 5 years, IgA, IgM and IgG levels were compared to 12 other c...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02239191
更新日期:1988-09-01 00:00:00
abstract::Systemic sclerosis (SSc) is complicated by pulmonary hypertension and right ventricle (RV) failure in approximately 10% of the patients. Factors influencing the reactivity of pulmonary circulation to vasodilators are not established, while the examination of vasoreactivity is important in determining the treatment, be...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-011-1792-4
更新日期:2012-01-01 00:00:00
abstract::Scleredema (also called scleredema of Buschke) is a fibromucinous connective tissue disorder of unknown cause that belongs to a group of scleroderma-like disorders. We report the case of a 64-year-old lady with long-standing scleredema, associated with a paraprotein, and progressing to multiple myeloma and AL amyloido...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-004-1076-3
更新日期:2006-02-01 00:00:00
abstract::We reviewed the records of 315 patients with rheumatoid arthritis (RA) treated with low-dose methotrexate (MTX) and evaluated the conditions contributing to thrombocytopenia. Thirteen out of 315 patients with RA presented with low platelet counts (< or = 100.000/mm3). The age of these patients (51 +/- 12.6 years) did ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02230334
更新日期:1996-03-01 00:00:00
abstract:OBJECTIVES:The invalidation or social pain is an important but neglected issue in polysymptomatology of fibromyalgia (FM). This study sought whether tracing-perceived invalidation could be effective to discriminate between the presence and absence of FM in chronic pain patients with respect to five different sources, i...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-05515-4
更新日期:2021-01-07 00:00:00
abstract::The aim of this study was to investigate the clinical features, risk factors, and outcomes of septic arthritis in patients on maintenance hemodialysis (HD). We systematically reviewed medical records of 16 HD patients with septic arthritis admitted to our hospital from April 2008 to April 2018. A total of 16 HD in pat...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-05114-3
更新日期:2020-10-01 00:00:00
abstract::The antichromatin antibody (aCT) has been described as a useful marker for lupus nephropathy. The relevance of its nephritogenic potential may be appropriately evaluated in the context of renal histopathology. Therefore, the present study investigated the relationship of aCT with a particular histopathologic class of ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-008-0939-4
更新日期:2008-11-01 00:00:00
abstract::The objective of the study was to determine clinical factors associated with activity limitation and predictors of a change in activity limitation after 1 year in people with gout. Two hundred ninety-five participants with gout (disease duration < 10 years) attended a baseline assessment which included medical and dis...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-018-4110-6
更新日期:2018-08-01 00:00:00
abstract::Low-dose naltrexone (LDN) has been demonstrated to reduce symptom severity in conditions such as fibromyalgia, Crohn's disease, multiple sclerosis, and complex regional pain syndrome. We review the evidence that LDN may operate as a novel anti-inflammatory agent in the central nervous system, via action on microglial ...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-014-2517-2
更新日期:2014-04-01 00:00:00
abstract::The objective of this study was to determine possible differences in the outcome of patients with rheumatoid arthritis (RA) with disease onset early and late in life. As part of a broader outcome study of RA which included patients seen in the division of Rheumatology of Hospital Universitario Marqués de Valdecilla of...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-004-1067-4
更新日期:2005-09-01 00:00:00
abstract::A 22-year-old African male with known sickle cell anaemia was referred by a Congolese medical centre with a request to improve his poor physical condition. He was unable to walk, stand or sit because his large joints and his spine were either ankylosed or very rigid. Radiographs showed joint fusion from the third to t...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s100670070047
更新日期:2000-01-01 00:00:00
abstract::To study the clinical characteristics of autoimmune rheumatic disease-related organizing pneumonia (AIRD-OP), the clinical presentation, radiological findings, treatment, and outcome of AIRD-OP patients were analyzed, in comparison with patients with cryptogenic organizing pneumonia (COP). A total of 131 OP patients w...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-017-3694-6
更新日期:2018-04-01 00:00:00
abstract:PURPOSE:To explore the 18F-fluoro-dexoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) imaging characteristics of adult-onset Still's disease (AOSD) and its significance in differential diagnosis from other connective tissue diseases (CTDs). METHODS:FDG PET/CT images of 54 patients with AOSD...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-05041-3
更新日期:2020-09-01 00:00:00
abstract::The aim of this study was to determine the serum interleukin-18 (IL-18) levels in patients with systemic lupus erythematosus (SLE) and to assess their relationship with disease activity. Thirty-five patients with SLE and 35 age- and sex-matched controls were enrolled in this study. Paired serum samples were collected ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-004-0867-x
更新日期:2004-06-01 00:00:00
abstract::Although peripheral blood eosinophilia is observed in patients with active inflammatory rheumatoid arthritis (RA), RA is not a recognised cause of pulmonary eosinophilia. We describe a 55-year-old woman affected by chronic eosinophilic pneumonia (CEP) concomitantly with an initiation of RA. Both diseases responded rap...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-003-0703-8
更新日期:2003-09-01 00:00:00