Abstract:
:Streptococcus is well associated with a myriad of inflammatory diseases. Among others, this bacterium is linked to the triggering of psoriasis and to post-streptococcal reactive arthritis (PSRA), an arthritis which is typically confined to peripheral joints. Three patients who developed acute psoriatic spondyloarthritis (SpA) following a recent streptococcal infection are described in this article. We searched the existing literature for cases of axial involvement in PSRA and reviewed the association between streptococcal infection and psoriasis or psoriatic arthritis )PsA). In all patients, psoriatic SpA occurred within 7-10 days of a confirmed streptococcal infection. The main presenting syndrome was inflammatory back pain with evidence of acute axial spondyloarthritis on magnetic resonance imaging. One patient had guttate psoriasis, the second patient developed pustular psoriasis, and the third patient had exacerbation of pustular palmoplantar psoriasis. Two patients required treatment with tumor necrosis factor alpha (TNF-α) blockers. Axial involvement in PSRA is very rare. A potential association of streptococcal infection and development of PsA has been explored in several articles. However, to the best of our knowledge, acute psoriatic SpA as a manifestation of PSRA has yet to be described. Acute psoriatic SpA should be considered in the differential diagnosis of new-onset inflammatory back pain followed by psoriasis in young adults who had a recent throat infection. KEY POINTS: • Our case series describes three cases of acute psoriatic spondyloarthritis that occurred within 7--10 days of a confirmed streptococcal infection and progressed to full blown chronic disease. • Acute psoriatic spondyloarthritis as a manifestation of post streptococcal reactive arthritis should be considered in the differential diagnosis of new onset inflammatory back pain followed by psoriasis in young adults who had a recent throat infection.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Dagan A,Dahan S,Shemer A,Langevitz P,Hellou T,Davidson T,Shoenfeld Y,Shovman Odoi
10.1007/s10067-019-04695-ysubject
Has Abstractpub_date
2019-09-01 00:00:00pages
2367-2372issue
9eissn
0770-3198issn
1434-9949pii
10.1007/s10067-019-04695-yjournal_volume
38pub_type
杂志文章,评审abstract::Ankylosing spondylitis (AS) is the prototype for spondyloarthritis primarily affecting young men. Geographic and ethnic variations exist in the prevalence and severity of AS and relate to the wide disparity in the frequency of human leukocyte antigen (HLA)-B27, a major genetic risk factor. The strength of the disease ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-012-2058-5
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abstract::Rheumatoid arthritis (RA) is well known to affect many different organ systems. Previous work suggests that this includes the auditory system and that measures of hearing may be related to indices of RA disease activity. The aims of this study were to determine whether hearing loss in young subjects with rheumatoid ar...
journal_title:Clinical rheumatology
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doi:10.1007/s10067-007-0802-z
更新日期:2008-05-01 00:00:00
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doi:10.1007/s10067-020-05235-9
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pub_type: 杂志文章,多中心研究
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journal_title:Clinical rheumatology
pub_type: 杂志文章
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-005-0058-4
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pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章,评审
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doi:10.1007/s10067-010-1581-5
更新日期:2011-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/BF01450894
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pub_type: 杂志文章
doi:10.1007/BF02204452
更新日期:1988-06-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s10067-018-4026-1
更新日期:2018-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s10067-020-05306-x
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s100670050131
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更新日期:2006-05-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 临床试验,杂志文章
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pub_type: 杂志文章,评审
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更新日期:2020-04-01 00:00:00
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pub_type: 杂志文章,meta分析
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1007/s10067-017-3928-7
更新日期:2018-06-01 00:00:00
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更新日期:2009-07-01 00:00:00