Abstract:
:We report a case of bleomycin-induced scleroderma in a 35-year-old woman treated with chemotherapy for Hodgkin's disease. Approximately 6 months after the first chemotherapy cycle, the patient developed skin sclerosis in both arms. The lesion showed no signs of spontaneous clinical amelioration and treatment with steroids was unsuccessful. A partial remission of the skin sclerosis was instead obtained by the administration of D-penicillamine. A family history revealed other cases of autoimmune diseases and HLA typing showed the presence of antigens associated with scleroderma. The association between bleomycin therapy and scleroderma is discussed.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Passiu G,Cauli A,Atzeni F,Aledda M,Dessole G,Sanna G,Nurchis P,Vacca A,Garau P,Laudadio M,Mathieu Adoi
10.1007/s100670050131subject
Has Abstractpub_date
1999-01-01 00:00:00pages
422-4issue
5eissn
0770-3198issn
1434-9949journal_volume
18pub_type
杂志文章abstract:INTRODUCTION/OBJECTIVES:The primary objective was to evaluate the impact of an in-department pharmacist on the prevention of drug iatrogenesis in a rheumatology department. Secondary objectives were to determine (i) if medication history discrepancies were detected more frequently in the elderly or not, and (ii) if the...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-05138-9
更新日期:2021-01-01 00:00:00
abstract::Erdheim-Chester disease (ECD) is a disseminated non-Langerhans' cell histiocytosis with multisystem involvement, including characteristic sclerotic musculoskeletal lesions. We present the case of a 27-year-old woman with a fulminant course and atypical involvement by ECD manifesting as extensive cerebrovascular diseas...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-003-0784-4
更新日期:2003-12-01 00:00:00
abstract::We investigated some steps in the signal transduction pathway leading to the proliferation of synovial cells. 12-o-tetradecanoyl phorbol-13-acetate (TPA) which is known to stimulate phospholipid- and Ca(2+)-dependent protein kinase (C-kinase) enhanced the proliferation of synovial cells. The proliferation of synovial ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02207092
更新日期:1992-03-01 00:00:00
abstract::Spontaneous fractures of the sternum are rare but worth knowing as they may simulate acute cardiac and pulmonary emergencies. A case of an insufficiency sternal fracture mimicking myocardial infarction and subsequent anginal pain is presented. The risk factors of this condition, its clinical features and the diagnosti...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02207687
更新日期:1995-07-01 00:00:00
abstract::Subcutaneous nodules are the most common conspicuous extra-articular manifestation of rheumatoid arthritis (RA). Cardiovascular disease (CVD) is the leading cause of death in patients with RA. The objective of this study is to examine the possibility of a relationship between subcutaneous nodules and "first ever" card...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-015-3032-9
更新日期:2015-10-01 00:00:00
abstract::A variety of systemic autoimmune disorders have been reported in patients with myelodysplastic and myeloproliferative syndromes. A possible association with polymyalgia rheumatica and giant cell arteritis has also been recognised. We report another case of polymyalgia rheumatica and one of giant cell arteritis associa...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s100670200081
更新日期:2002-08-01 00:00:00
abstract::The objective of this study is to assess the usefulness of the stand-alone renal SLICC criterion in patients with childhood systemic lupus erythematosus (cSLE) and report their disease course, treatment response, and outcome. This study included children who were followed regularly in our lupus clinic with proved full...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-019-04789-7
更新日期:2020-02-01 00:00:00
abstract::This cross-sectional investigation examined the prevalence and severity of dysphonia, globus pharyngeus, and dysphagia in patients affected by immunomediated (IM) diseases. Seventy subjects were administered the Voice Handicap Index (VHI) (scale 0-4), Glasgow-Edinburgh Throat Scale (GETS) (scale from 0 to 7) for globu...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-018-4129-8
更新日期:2019-01-01 00:00:00
abstract::Systemic lupus erythematosus (SLE) patients had an increased susceptibility to tuberculosis (TB). The aim of this study was to investigate the prevalence and clinical characteristics of TB in SLE patients, with focus on the differences between pulmonary and extra-pulmonary TB. This is a retrospective study that review...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-007-0741-8
更新日期:2008-05-01 00:00:00
abstract::The objective of this study was to describe ultrasonography (US) and magnetic resonance imaging (MRI) findings at painful Achilles tendons and entheses in patients with and without spondyloarthropathy (SpA and non-SpA) and healthy control persons (CTRLs). Particularly, we aimed to investigate if any changes differenti...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-012-2111-4
更新日期:2013-03-01 00:00:00
abstract::Intussusception is characterized by one segment of the gastrointestinal tract telescoping into the lumen of the adjacent segment; it is rarely reported in systemic lupus erythematosus (SLE), and the condition can be threatening. Only four cases of intussusception with SLE have been reported in literature. Here, we des...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-017-3879-z
更新日期:2018-01-01 00:00:00
abstract::The authors describe an atypical case of a patient having giant cell arteritis presenting only with fever, diagnosed by positron emission tomography and subsequently confirmed by temporal artery biopsy. ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-007-0831-7
更新日期:2008-06-01 00:00:00
abstract::The aim of this study is to compare effectiveness and safety of Infliximab (INF), Etanercept (ETN), and Adalimumab (ADA) in patients with psoriatic arthritis (PsA) with inadequate response to a previous disease-modifying antirheumatic drug (DMARD). One hundred consecutive PsA patients with inadequate response to a pre...
journal_title:Clinical rheumatology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10067-009-1340-7
更新日期:2010-04-01 00:00:00
abstract::Coexistence of rheumatoid arthritis and gout is considered to be unusual. The current study was designed as a population-based cross-sectional study, utilizing the medical database of Clalit Health Services, the largest healthcare provider organization in Israel. Data of adult patients who were previously diagnosed wi...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-016-3477-5
更新日期:2017-03-01 00:00:00
abstract::Sternoclavicular septic arthritis is a rare complication of subclavian venous catheterization. We estimate that septic involvement of this joint may be as common as one in 500 catheterizations. We report two patients with insidious onset of shoulder pain, chest discomfort, low-grade fever and slight but painful swelli...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02242953
更新日期:1994-09-01 00:00:00
abstract::The aim of this study was to analyse microvascular damage and compensatory angiogenesis in skin from patients with systemic sclerosis (SSc) compared with systemic lupus erythematosus (SLE), Raynaud's phenomenon (RP) and healthy controls. Immunohistochemistry was used for skin biopsies (9 SSc, 10 SLE, 9 RP and 12 healt...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-003-0698-1
更新日期:2003-09-01 00:00:00
abstract::To compare rheumatologists' adherence to treatment protocols for rheumatoid arthritis (RA) targeted at Disease Activity Score (DAS) ≤2.4 or <1.6. The BeSt-study enrolled 508 early RA (1987) patients targeted at DAS ≤2.4. The IMPROVED-study included 479 early RA (2010) and 122 undifferentiated arthritis patients target...
journal_title:Clinical rheumatology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s10067-016-3405-8
更新日期:2017-02-01 00:00:00
abstract:INTRODUCTION:Studies conducted by various scientific societies have shown that the demand for specialized rheumatology care is greater than the projected growth of the workforce. Our research aims to assess the current status of the rheumatology workforce in Latin America. METHOD:This is a descriptive, cross-sectional...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-05555-w
更新日期:2021-01-15 00:00:00
abstract::Familial Mediterranean fever (FMF) is prevalent among Arabic, Turkish, Armenian, and Jewish people and it must always be considered in the differential diagnosis of patients from these ethnic groups presenting with recurrent abdominal pain with fever. In cases of fever and recurrent abdominal pain, acute pancreatitis ...
journal_title:Clinical rheumatology
pub_type: 信件
doi:10.1007/s10067-004-0922-7
更新日期:2004-12-01 00:00:00
abstract:INTRODUCTION:Alkaptonuria (AKU) is a rare metabolic disease. The global incidence is 1:100,000 to 1:250,000. However, identification of a founder mutation in a gypsy population from India prompted us to study the prevalence of AKU in this population and to do molecular typing in referred cases of AKU from the rest of I...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-05020-8
更新日期:2020-09-01 00:00:00
abstract::Psoriatic arthritis (PsA) is an inflammatory arthropathy, associated with skin and/or nail psoriasis and other possible systemic features. In the last years, PsA therapy has been revolutionized by the increasing knowledge in the pathogenetic mechanisms of the disease, involving dysfunction and oversecretion of multipl...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-014-2603-5
更新日期:2014-09-01 00:00:00
abstract::Takayasu's arteritis (TA) is a chronic inflammation that frequently involves the aorta and its major branches. The clinical features of TA vary in different ethnic populations. The objective of this study is to characterize the clinical features, angiographic findings, and response to treatment of patients with TA in ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-010-1496-1
更新日期:2010-09-01 00:00:00
abstract::Paroxysmal crises of fever and systemic inflammation herald familial Mediterranean fever (FMF), considered as the archetype of all inherited systemic autoinflammatory diseases. Inflammatory bouts are characterized by short-term and self-limited abdominal, thoracic, and/or articular symptoms which subside spontaneously...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-015-2916-z
更新日期:2015-09-01 00:00:00
abstract::The authors studied the incidence of atlanto-axial joint involvement by conventional radiography and CT in 183 patients with classical or definite rheumatoid arthritis (RA). In determining lesions the significance of factors such as age, sex, duration and severity of the disease was evaluated. Atlanto-axial subluxatio...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02242943
更新日期:1994-09-01 00:00:00
abstract::Two cases of Paget's sarcoma of bone are described. The first one is mainly characterized by the almost simultaneous degeneration of the only two existing locations of the underlying Paget's disease. The second case is one of monostotic Paget's disease of the scapula disclosed by the malignant degeneration. ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02031268
更新日期:1984-12-01 00:00:00
abstract::The aim of this research was to determine any correlations between Dickkopf-1 serum levels (Dkk-1, a natural inhibitor of the Wnt signaling pathway promoting osteoclastogenesis) and the Trabecular Bone Score (TBS), in systemic sclerosis (SSc) and rheumatoid arthritis (RA) patients. It also aimed at determining any dif...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-018-4322-9
更新日期:2018-11-01 00:00:00
abstract::Delayed diagnosis in patients with Churg-Strauss syndrome (CSS) is largely attributed to the variable and nonspecific presentation of the disease's initial symptoms. The aim of the study was to evaluate the effect of delayed diagnosis on the course of CSS. We conducted a retrospective study of 30 CSS patients followed...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-012-2127-9
更新日期:2013-03-01 00:00:00
abstract::We report the case of a woman who developed chorea in her neck, trunk, and extremities soon after taking gabapentin as treatment for complex regional pain syndrome Type 1. The chorea lasted for a year and resolved completely within 2 weeks of discontinuing gabapentin. ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-007-0744-5
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVE:This study was designed to compare outcomes of dose reduction, withdrawal, and continuation of tofacitinib in patients with rheumatoid arthritis (RA) and to examine effectiveness of rescue with an original treatment regimen for disease flare. METHODS:We prospectively enrolled 100 patients who had high or mod...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-019-04721-z
更新日期:2019-12-01 00:00:00
abstract::Erythema nodosum is an unusual manifestation of Hodgkin's lymphoma. One patient with long remission of Hodgkin's disease manifested persistent erythema nodosum beginning one and three months before relapse was clinically evident. So, the diagnosis of Hodgkin's disease should be considered in patients with unexplained ...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/BF02114402
更新日期:1990-09-01 00:00:00