Efficacy of tocilizumab in a patient with refractory psoriatic arthritis.

abstract：OBJECTIVE:This case-control study aimed to analyze the clinical features and determine the expression of type I interferon-induced genes in systemic lupus erythematosus (SLE) patients harboring the CD11b rs1143679 single-nucleotide polymorphism (SNP) and elucidate whether it is involved in the relapses of SLE. METHODS...

journal_title：Clinical rheumatology

authors： Xu W,Zhang Y,Wang X,Liu P,Gao D,Gu B,Zhang J,Li C,Ren Q,Yang L,Yuan H,Shen M,Chen X

更新日期：2020-08-12 00:00:00

abstract：:Immunoglobulins are often high in active rheumatoid arthritis and fall when treatment with a slow-acting anti-rheumatic drug is instituted. We assessed the value of monitoring immunoglobulins during penicillamine therapy; 145 patients were followed for up to 5 years, IgA, IgM and IgG levels were compared to 12 other c...

journal_title：Clinical rheumatology

authors： Williams A,Scott DL,Greenwood A,Huskisson EC

更新日期：1988-09-01 00:00:00

abstract：:A 71-year-old male rheumatoid patient presented with MRSA septic arthritis. The impact of this organism on musculoskeletal practice is discussed. ...

journal_title：Clinical rheumatology

authors： Byrne PA,Hosein IK,Camilleri J

更新日期：1998-01-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is associated with increased vascular calcification, although the rate of progress of calcification is uncertain. The aim of the study was to evaluate the progression of and the predictors for calcification in different vascular beds over 10 years. The 10-year actual coronary calcium score (C...

journal_title：Clinical rheumatology

authors： Liu JH,Ng MY,Cheung T,Chung HY,Chen Y,Zhen Z,Zou Y,Mak KF,Khong PL,Lau CS,Tse HF,Yiu KH

更新日期：2017-04-01 00:00:00

abstract：:We investigated some steps in the signal transduction pathway leading to the proliferation of synovial cells. 12-o-tetradecanoyl phorbol-13-acetate (TPA) which is known to stimulate phospholipid- and Ca(2+)-dependent protein kinase (C-kinase) enhanced the proliferation of synovial cells. The proliferation of synovial ...

journal_title：Clinical rheumatology

authors： Yamamoto M,Yasuda M,Shiokawa S,Nobunaga M

更新日期：1992-03-01 00:00:00

abstract：:Joint lavage for knee osteoarthritis is an invasive procedure that can be stressful and painful. We aimed to assess the impact of music therapy on perioperative anxiety, pain and tolerability of the procedure in patients undergoing joint lavage performed with two needles. We randomized all patients diagnosed with knee...

journal_title：Clinical rheumatology

authors： Ottaviani S,Bernard JL,Bardin T,Richette P

更新日期：2012-03-01 00:00:00

abstract：:We investigated, in retrospect, if there were differences in the frequency and types of abdominal surgery between newly diagnosed female fibromyalgia (n = 80) and rheumatoid arthritis (n = 47) patients performed before the formal diagnosis. There was no difference in the total number of abdominal operations between bo...

journal_title：Clinical rheumatology

authors： ter Borg EJ,Gerards-Rociu E,Haanen HC,Westers P

更新日期：1999-01-01 00:00:00

abstract：:The level of the N terminal fragment of procollagen III (P3NP) levels of 100 consecutive patients affected by rheumatoid arthritis (RA) were evaluated in comparison with disease activity markers (erythrocytes sedimentation rate, C reactive protein), immunological status (rheumatoid factors, immune complexes) and joint...

journal_title：Clinical rheumatology

authors： Tebib JG,Viguier P,Noel E,Colson F,Barbier Y,Bouvier M

更新日期：1992-12-01 00:00:00

abstract：:In a patient suffering from rheumatoid arthritis, we report the first simultaneous occurrence of two side effects of low-dose methotrexate: an acute megaloblastic anaemia and a pneumonitis. A combination of methotrexate suspension, folinic acid and corticosteroids led to recovery. The correlation between the haematolo...

journal_title：Clinical rheumatology

authors： Bolla G,Disdier P,Harle JR,Verrot D,Weiller PJ

更新日期：1993-12-01 00:00:00

abstract：:The authors studied the incidence of atlanto-axial joint involvement by conventional radiography and CT in 183 patients with classical or definite rheumatoid arthritis (RA). In determining lesions the significance of factors such as age, sex, duration and severity of the disease was evaluated. Atlanto-axial subluxatio...

journal_title：Clinical rheumatology

authors： Montemerani M,Venturi C,Bracco S,Coviello G,Minari C,Fioravanti A,Marcolongo R

更新日期：1994-09-01 00:00:00

abstract：:Idiopathic retroperitoneal fibrosis (IRPF) is a rare condition of unknown aetiology characterized by chronic non-specific inflammation of the retroperitoneum. The aim of this study is to describe, for the first time, the features of Spanish patients with IRPF. In this retrospective study, a clinical description was pe...

journal_title：Clinical rheumatology

authors： Fernández-Codina A,Martínez-Valle F,Castro-Marrero J,Detorres I,Vilardell-Tarrés M,Ordi-Ros J

更新日期：2013-06-01 00:00:00

abstract：:Juvenile dermatomyositis (JDM) is a rare chronic inflammatory disease of unknown etiology and primarily involves muscle and skin. It is the most common idiopathic inflammatory myopathy of childhood. This study aimed to evaluate demographic and clinical features, laboratory data, treatment modalities, and outcome of pa...

journal_title：Clinical rheumatology

authors： Barut K,Aydin PO,Adrovic A,Sahin S,Kasapcopur O

更新日期：2017-02-01 00:00:00

abstract：:The antichromatin antibody (aCT) has been described as a useful marker for lupus nephropathy. The relevance of its nephritogenic potential may be appropriately evaluated in the context of renal histopathology. Therefore, the present study investigated the relationship of aCT with a particular histopathologic class of ...

journal_title：Clinical rheumatology

authors： Carvalho JF,Viana VS,Borba EF,do Nascimento AP,Leon EP,Testagrossa LA,Barros RT,Bonfá E

更新日期：2008-11-01 00:00:00

abstract：INTRODUCTION:Interleukin-1 receptor-associated kinases (IRAKs) are serine-threonine kinases involved in toll-like receptor and interleukin-1 signaling pathways. They play a key role in inflammation and innate immunity. IRAKs have been previously incriminated in autoimmune diseases such as systemic lupus erythematosus (...

journal_title：Clinical rheumatology

authors： Boumiza A,Zemni R,Sghiri R,Idriss N,Hassine HB,Chabchoub E,Mzabi A,Ghannouchi N,Bouajina E,Ben Hadj Slama F

更新日期：2020-02-01 00:00:00

abstract：:The aim of this study was to assess the role of oxidative stress in the pathogenesis of Henoch-Schönlein purpura (HSP) vasculitis. The activities of catalase (CAT), arylesterase (ARYL), and paraoxonase (PON) as antioxidant enzymes and serum malondialdehyde (MDA) level as an indicator of lipid peroxidation, together wi...

journal_title：Clinical rheumatology

authors： Ece A,Kelekçi S,Kocamaz H,Hekimoğlu A,Balik H,Yolbaş I,Erel O

更新日期：2008-02-01 00:00:00

abstract：:This study was designed to explore the profile of immune cell subsets, including T, B, natural killer (NK), and NKT cells, in systemic lupus erythematosus (SLE) patients, and to determine their relationships with the clinical index and the effects of cyclophosphamide (CYC) and mycophenolate mofetil (MMF) treatment. SL...

journal_title：Clinical rheumatology

authors： Zhao L,Jiang Z,Jiang Y,Ma N,Wang K,Zhang Y

更新日期：2012-06-01 00:00:00

abstract：:The first name of the co-author of the above article was presented incorrect in the published version. The author name "Miangliang Qiu" should read "Mingliang Qiu" as mentioned above. ...

journal_title：Clinical rheumatology

authors： Qiu M,Mo L,Li J,Liang H,Zhu W,Zheng X,Duan X,Xu W

更新日期：2020-03-01 00:00:00

abstract：:Takayasu arteritis (TA) is a chronic inflammatory disease. Interleukin (IL)-6 and IL-10 are important cytokines involved in the immune response of TA in some ethnicities. We investigated whether the single-nucleotide polymorphism (SNP) of IL-6 and IL-10 genes and their expressions were associated with TA in a Chinese ...

journal_title：Clinical rheumatology

authors： Gao Q,Lv N,Dang A,Li Z,Ye J,Zheng D

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:Rheumatoid arthritis (RA) may increase the risk of anxiety, but results from prior studies have no consensus. Our study aimed to evaluate the relationship between RA and incident anxiety by using a quantitative meta-analysis. METHODS:A number of databases were used to gather relevant information; they inclu...

journal_title：Clinical rheumatology

authors： Qiu XJ,Zhang XL,Cai LS,Yan C,Yu L,Fan J,Zhang RW,Huang JW,Duan XW

更新日期：2019-08-01 00:00:00

abstract：:Haemorrhoidal disease (HD) is one of the most common diseases encountered by the clinicians of general surgery. Chronic constipation, pushing during defecation and increased abdominal pressure play an important role in development of haemorrhoidal disease. Patients with ankylosing spondylitis (AS) frequently use the V...

journal_title：Clinical rheumatology

authors： Caglayan M,Türkoğlu A,Oktayoglu P,Yıldız M,Dağlı AZ,Böyük A,Em S,Bozkurt M,Nas K

更新日期：2015-03-01 00:00:00

abstract：:Little data exists from the developing world on pregnancy in systemic lupus erythematosus (SLE). A 10-year review of pregnancies in lupus patients was conducted at a tertiary hospital in a developing country. Forty-seven pregnancies in 31 patients were identified. Eleven (23%) booked after 20 weeks gestation. There we...

journal_title：Clinical rheumatology

authors： Whitelaw DA,Hall D,Kotze T

更新日期：2008-05-01 00:00:00

abstract：:The original published version of this article contained the incorrect Table 2 and are now presented correctly in this article. ...

journal_title：Clinical rheumatology

authors： Idolazzi L,Zabotti A,Fassio A,Errichetti E,Benini C,Vantaggiato E,Rossini M,De Vita S,Viapiana O

更新日期：2020-04-01 00:00:00

abstract：:This study aims to develop a sandwich ELISA system for the measurement of soluble folate receptor β (sFRβ) and evaluate whether base line levels of serum sFRβ are a biomarker for the activity of RA synovitis and the response to anti-TNF agents. Serum sFRβ from normal controls (41 samples), patients with OA (29 samples...

journal_title：Clinical rheumatology

authors： Otsubo H,Tsuneyoshi Y,Nakamura T,Matsuda T,Komiya S,Matsuyama T

更新日期：2018-11-01 00:00:00

abstract：:The aim of this systematic review was to determine the potential role of dual-energy CT in the diagnosis and follow-up of gout with regard to the Outcome Measures in Rheumatology (OMERACT) filter. A systematic analysis of the literature was conducted using the MEDLINE and Cochrane databases and published abstracts of ...

journal_title：Clinical rheumatology

authors： Ramon A,Bohm-Sigrand A,Pottecher P,Richette P,Maillefert JF,Devilliers H,Ornetti P

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVES:This study aimed to investigate the relationship among smoking, TNF-α-blocker therapy, and the dynamic changes in gut microbiota in patients with ankylosing spondylitis (AS). METHODS:Using a 16S rRNA sequence, 98 fecal samples of 20 AS patients collected after 0, 1, 3 and 6 months of anti-TNF-α treatment an...

journal_title：Clinical rheumatology

authors： Zhang F,Ma C,Zhang B,Bi L

更新日期：2020-09-01 00:00:00

abstract：:Idiopathic Inflammatory myopathies (IIM) are rare disorders. The aim of our study was to determine the incidence of IIM in a well-defined Slovenian region. This retrospective study was conducted at the Department of Rheumatology, University Medical Centre Ljubljana, the only secondary/tertiary rheumatology center in a...

journal_title：Clinical rheumatology

authors： Ostrovršnik J,Hočevar A,Rotar Ž,Krošel M,Čučnik S,Jurčić V,Tomšič M

更新日期：2019-02-01 00:00:00

abstract：:Anti-nucleosome antibodies, which recognise conformational epitopes consisting of histone and DNA in chromatin, have been described in autoimmune diseases. In this study, an attempt was made to isolate anti-nucleosome antibodies from the anti-DNA-depleted plasma IgG of two lupus patients either with or without nephrit...

journal_title：Clinical rheumatology

authors： Suenaga R,Mitamura K,Abdou NI

更新日期：1998-01-01 00:00:00

abstract：:Behçet's disease is a systemic vasculitic syndrome with unknown etiology. The aim of the present study was to compare the Helicobacter pylori seropositivity and cytotoxin associated gene-A status in patients with Behçet's disease. Ninety-one patients with Behçet's disease and 83 age- and sex-matched persons with or wi...

journal_title：Clinical rheumatology

authors： Apan TZ,Gürsel R,Dolgun A

更新日期：2007-06-01 00:00:00

abstract：:Biologic therapies have brought improved efficacy in the field of rheumatoid arthritis (RA), but their use in clinical practice may be limited by concerns over cost. Predictive models are, therefore, needed to identify those people with RA with the worst potential outcomes, who will benefit most from the use of these ...

journal_title：Clinical rheumatology

authors： Conaghan PG

更新日期：2011-03-01 00:00:00

abstract：:The aim of the study was to describe the long-term toxicity of antirheumatic and anti-inflammatory drugs in a paediatric rheumatology clinic population. One hundred and seventeen children were studied on first admission to a paediatric rheumatology clinic and after a mean of 8.6 +/- 0.4 years of follow-up. Medical rec...

journal_title：Clinical rheumatology

authors： Flatø B,Vinje O,Førre O

更新日期：1998-01-01 00:00:00