A survey of renal function in outpatients with rheumatoid arthritis.

Abstract:

:The acute renal side-effects of nonsteroidal anti-inflammatory drugs are well documented. These include interstitial nephritis, hyperkalaemia, renal tubular acidosis, fluid retention, hypertension and nephrotic syndrome. The long-term effects are less well known. We have carried out a cross-sectional survey of an unselected out-patient population with definite or classical rheumatoid arthritis to determine the prevalence of renal problems in this group. Thirty-four patients (20%) were shown to have an abnormality as defined by our criteria but in the majority this was transient or had been previously recognised. Thirteen patients (8%) had a persistent unexplained abnormality but only 1 had merited renal biopsy using established criteria (Patient 1). We conclude that the long-term use of NSAID's is associated with relatively few renal side-effects.

journal_name

Clin Rheumatol

journal_title

Clinical rheumatology

authors

Richards IM,Fraser SM,Capell HA,Fox JG,Boulton-Jones JM

doi

10.1007/BF02204466

subject

Has Abstract

pub_date

1988-06-01 00:00:00

pages

267-71

issue

2

eissn

0770-3198

issn

1434-9949

journal_volume

7

pub_type

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