Abstract：
:The aim of the study was to demonstrate the effectiveness of sulphurous water in patients with osteoarthritis of the hand. Forty-seven patients with osteoarthritis of the hand were enrolled into the double-blind, randomized, controlled study, satisfying ACR criteria. One group of the patients (n = 24) received balneotherapy, bathing in sulphurous thermal water for 20 min per occasion, 15 times in all during a period of 3 weeks. The control group (n = 21) had a bath exclusively in warm tap water. Assessments were carried out in both groups on four occasions: at the beginning and at the end of the treatment, and 3 and 6 months after the beginning of the treatment. The parameters studied were the following: pain in the hand, morning stiffness in the joints, grip strength of both hands, and Health Assessment Questionnaire Disability Index (HAQ) and AUSCAN Hand Osteoarthritis Index and EuroQol quality of life questionnaire. At the end of treatment, the improvement was more pronounced in the patient group treated with the sulphurous water. After 3 months, significant improvement could be detected in all parameters, except the morning stiffness and EQ5D. After 6 months, the values of pain, HAQ and AUSCAN continued to be significantly better in comparison with the baseline values. The improvement in quality of life was significant only at the end of the treatment, 6 months later not any longer. The difference between the two groups was significant after 3 months in point of pain and EQVAS. Balneotherapy and within this the sulphurous spa water alone may be effective for the attenuation of pain in patients with hand osteoarthrosis.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Kovács C,Pecze M,Tihanyi Á,Kovács L,Balogh S,Bender Tdoi
10.1007/s10067-012-2026-0subject
Has Abstractpub_date
2012-10-01 00:00:00pages
1437-42issue
10eissn
0770-3198issn
1434-9949journal_volume
31pub_type
杂志文章,随机对照试验abstract：:MicroRNAs (miRNAs) are non-coding RNAs that regulate gene expression of targeted mRNAs, which are important in the pathogenesis of autoimmune diseases. MiRNAs may have the potential to serve as biomarkers of disease. We evaluated serum levels of selected miRNAs and their associations with disease activity in juvenile ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-015-2922-1
更新日期：2015-10-01 00:00:00
abstract：:Initial treatment of trapeziometacarpal osteoarthritis (TMO) often consists of intra-articular injection of corticosteroids or hyaluronic acid. Several studies have shown that ultrasound (US)-guided injections demonstrate greater precision and effectiveness when compared to blind techniques. The aim of our study was t...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-011-1730-5
更新日期：2011-09-01 00:00:00
abstract：:Antibodies to beta(2)-glycoprotein I (anti-beta(2)-GPI) have been reported to have stronger association with clinical antiphospholipid syndrome (APS) than anticardiolipin antibodies (aCL) and lupus anticoagulant (LAC). We investigated the sensitivity and specificity of ELISA for anti-beta(2)-GPI in Thai systemic lupus...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-007-0566-5
更新日期：2007-10-01 00:00:00
abstract：:Adult onset Still's disease (AOSD) is an inflammatory disease of unknown etiology, characterized by spiking fever, evanescent salmon pink maculopapular rash, arthritis, and leukocytosis with neutrophilia. Malignant lymphoma is one of the most important differential diagnoses of AOSD. AOSD has been reported as one of p...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-009-1305-x
更新日期：2010-02-01 00:00:00
abstract：:Familial Mediterranean fever (FMF) is prevalent among Arabic, Turkish, Armenian, and Jewish people and it must always be considered in the differential diagnosis of patients from these ethnic groups presenting with recurrent abdominal pain with fever. In cases of fever and recurrent abdominal pain, acute pancreatitis ...
journal_title：Clinical rheumatology
pub_type： 信件
doi：10.1007/s10067-004-0922-7
更新日期：2004-12-01 00:00:00
abstract：:The aim of this study was to investigate the clinical features, risk factors, and outcomes of septic arthritis in patients on maintenance hemodialysis (HD). We systematically reviewed medical records of 16 HD patients with septic arthritis admitted to our hospital from April 2008 to April 2018. A total of 16 HD in pat...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-020-05114-3
更新日期：2020-10-01 00:00:00
abstract：:Ankylosing spondylitis (AS) is the prototype for spondyloarthritis primarily affecting young men. Geographic and ethnic variations exist in the prevalence and severity of AS and relate to the wide disparity in the frequency of human leukocyte antigen (HLA)-B27, a major genetic risk factor. The strength of the disease ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-012-2058-5
更新日期：2012-11-01 00:00:00
abstract：:Mycoleptodiscus indicus is a recognized plant pathogen which has very rarely been reported as a cause of human infection. It is a tropical or subtropical fungus which is difficult to culture and identify from clinical specimens. This is the first report of septic arthritis with this fungus in a healthy Canadian male. ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-010-1448-9
更新日期：2010-09-01 00:00:00
abstract：OBJECTIVE:To investigate the clinical characteristics, laboratory features, and treatment outcomes of Thai patients compared between those with necrotizing autoimmune myopathy (NAM) and those with other idiopathic inflammatory myopathies (IIMs) or non-NAM. METHODS:This multicenter case-control study included patients ...
journal_title：Clinical rheumatology
pub_type： 杂志文章,多中心研究
doi：10.1007/s10067-019-04756-2
更新日期：2019-12-01 00:00:00
abstract：:The objective of the study was to study the functioning and health-related quality of life (HRQoL) in patients with systemic sclerosis (SSc) and its associated factors. Consecutive SSc patients and an equal number of age- and gender-matched healthy controls were recruited for the assessment of functioning and HRQoL by...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-014-2525-2
更新日期：2014-05-01 00:00:00
abstract：:Hepatitis C-associated osteosclerosis (HCAO) is an impressive example of acquired diffuse osteosclerosis in adults, recently described in ten patients infected with hepatitis C virus (HCV). Its hallmark is a painful and generalized increase of bone mass. Bone biopsies show enhanced accretion rate, usually without hist...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-004-1031-3
更新日期：2005-06-01 00:00:00
abstract：:Vitamin D is vital for musculoskeletal health and may be associated with subacute and chronic low back pain. The objective of this study was to estimate the prevalence of vitamin D deficiency among chronic low back pain (CLBP) and subacute low back pain (SLBP), and compare the same with healthy controls. This study wa...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3798-z
更新日期：2018-05-01 00:00:00
abstract：:To clarify the roles of neutrophils in anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitic neuropathy, we studied neutrophil extracellular traps (NETs) in peripheral nerve vasculitis. Stored nerve samples from 17 patients with microscopic polyangiitis (MPA) were immunohistochemically analyzed using a...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3546-4
更新日期：2017-04-01 00:00:00
abstract：:The objective of this study is to assess the usefulness of the stand-alone renal SLICC criterion in patients with childhood systemic lupus erythematosus (cSLE) and report their disease course, treatment response, and outcome. This study included children who were followed regularly in our lupus clinic with proved full...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-019-04789-7
更新日期：2020-02-01 00:00:00
abstract：:Systemic sclerosis (SSc) is an autoimmune disease which may lead to malnutrition. Previous studies have defined it with different criteria. No thorough evaluations of sarcopenia in SSc are available. The aim of the present study was to assess the prevalence and the potential association of malnutrition and sarcopenia ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3932-y
更新日期：2018-04-01 00:00:00
abstract：:The authors studied the incidence of atlanto-axial joint involvement by conventional radiography and CT in 183 patients with classical or definite rheumatoid arthritis (RA). In determining lesions the significance of factors such as age, sex, duration and severity of the disease was evaluated. Atlanto-axial subluxatio...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02242943
更新日期：1994-09-01 00:00:00
abstract：:The coexistence of polymyositis (PM) and primary biliary cirrhosis (PBC) is rare; only nine cases have been described in English literature. We report a case of a 46-year-old woman presenting with these two autoimmune diseases. The diagnosis of PM was based on the symmetrical, proximal limb muscle weakness, elevated m...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02208358
更新日期：1995-05-01 00:00:00
abstract：:This study quantified the association between recreational physical activity and daily function in women with fibromyalgia, and determined if this association is mediated by symptoms of pain, depression, or body mass. Twenty-three women diagnosed with fibromyalgia participated in an observational survey study. Recreat...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-013-2386-0
更新日期：2015-01-01 00:00:00
abstract：:We describe four cases of giant cell arteritis (GCA) that presented with occipital headache in the last 6 months. Typical ultrasound features of GCA were found in the occipital arteries which helped to confirm the diagnosis. One patient had already suffered significant visual loss by the time the diagnosis was made, r...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-017-3946-5
更新日期：2018-02-01 00:00:00
abstract：OBJECTIVES:In people with rheumatoid arthritis (RA), mental health problems are common, but often not recognized or treated, contributing to increased morbidity and mortality. Most studies examining the impact of mental health problems in RA have focused on depression. We aimed to determine the association between anxi...
journal_title：Clinical rheumatology
pub_type： 杂志文章,meta分析
doi：10.1007/s10067-019-04900-y
更新日期：2020-05-01 00:00:00
abstract：:The aim of the study was to determine the main demographic, epidemiological, clinical characteristics, and outcome in patients with various types of brucellar monoarticular involvement. Retrospectively, we analyzed medical histories of 331 patients with brucellar monoarticular involvement who were treated at the infec...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-016-3207-z
更新日期：2016-10-01 00:00:00
abstract：:This study aims to determine the prevalence and clinical significance of anti-CCP isotype IgA in a population of patients with primary Sjögren's syndrome (pSS). Sixty-two patients diagnosed according to the USA-European classification criteria for pSS were examined two to four times during a 60.4-month follow-up, and ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-010-1675-0
更新日期：2011-03-01 00:00:00
abstract：:The objective of this study was to describe ultrasonography (US) and magnetic resonance imaging (MRI) findings at painful Achilles tendons and entheses in patients with and without spondyloarthropathy (SpA and non-SpA) and healthy control persons (CTRLs). Particularly, we aimed to investigate if any changes differenti...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-012-2111-4
更新日期：2013-03-01 00:00:00
abstract：:The outbreak of SARS-CoV-2 has changed the habits and lives of people worldwide. Patients affected by systemic sclerosis (SSc) experienced constant fear because of their immunocompromised status. The aim of this study was to investigate the prevalence of SARS-CoV-2 infection and to analyze the lifestyle changes in a s...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-020-05504-7
更新日期：2020-11-14 00:00:00
abstract：:Ophthalmic involvement is the most debilitating complication of Behcet's disease (BD). The aim of the current study is to report on the efficacy and safety of a long-term use of interferon alpha-2a (IFNα-2a) in the treatment of refractory ophthalmic BD in the Azari population of Iran. We retrospectively analyzed the c...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-016-3318-6
更新日期：2016-11-01 00:00:00
abstract：:To compare the efficacy and safety of aceclofenac (AC) and tenoxicam (TX) in the treatment of rheumatoid arthritis (RA), a multicentric parallel, randomized, double-blind trial of three months duration was performed in 292 patients: 145 were randomized to the AC treatment group and 147 to the TX treatment group. The t...
journal_title：Clinical rheumatology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1007/BF02229644
更新日期：1996-09-01 00:00:00
abstract：:Adult-onset Still's disease (AOSD) is an autoimmune disease characterized by spiking fever, evanescent rash, arthritis, serositis, and liver involvement. Although autoimmune hepatitis (AIH) has been reported in association with various autoimmune diseases, AOSD-associated AIH is rare. We herein report an unusual case ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-009-1186-z
更新日期：2010-01-01 00:00:00
abstract：:Chronic pediatric musculoskeletal (MSK) conditions are a major cause of morbidity. The burden of pediatric rheumatic diseases in East Africa is largely unknown. The purposes of this study were to estimate frequencies and assess the spectrum of MSK-related diagnoses using ICD-10 diagnostic codes among outpatients at a ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-018-4376-8
更新日期：2019-04-01 00:00:00
abstract：:Systemic Sclerosis (SSc; scleroderma) is associated with several immunological abnormalities, including altered proportion between lymphocyte subsets. Peripheral blood lymphocyte subsets from 25 patients with SSc were studied by two-colour flow cytometry using monoclonal antibodies against CD45RA and CD29 markers, whi...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02229871
更新日期：1994-03-01 00:00:00
abstract：:Paroxysmal crises of fever and systemic inflammation herald familial Mediterranean fever (FMF), considered as the archetype of all inherited systemic autoinflammatory diseases. Inflammatory bouts are characterized by short-term and self-limited abdominal, thoracic, and/or articular symptoms which subside spontaneously...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-015-2916-z
更新日期：2015-09-01 00:00:00
