Abstract:
:Cardiovascular disease is a major health care problem and the most common cause of death among individuals from developed nations. Our understanding of atherosclerosis has evolved from a passive process resulting in narrowing of the lumen and consequent myocardial ischemia to a dynamic process that involves inflammation. The study of atherosclerosis in patients with chronic inflammation, such as rheumatoid arthritis (RA), will provide insights into the relationship between inflammation and atherosclerosis. We review the relationship between atherosclerosis and inflammation within the context of RA, providing evidence that patients with RA have increased cardiovascular morbidity and mortality and accelerated coronary and extra-coronary atherosclerosis. In addition, traditional and novel cardiovascular risk factors are discussed. Finally, actions that a rheumatologist can take to better control this cardiovascular morbidity are suggested. These can be summarized as follows: (1) careful assessment and treatment of cardiovascular risk, (2) better control of inflammation, and (3) individual risk-benefit evaluation of need for cyclo-oxygenase-2 inhibitors, nonsteroidal anti-inflammatory drugs, and high doses of corticosteroids.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Chung CP,Avalos I,Raggi P,Stein CMdoi
10.1007/s10067-007-0548-7subject
Has Abstractpub_date
2007-08-01 00:00:00pages
1228-33issue
8eissn
0770-3198issn
1434-9949journal_volume
26pub_type
杂志文章,评审abstract::Gastrointestinal tract (GIT) is the most common organ system involved in systemic sclerosis (SSc). GIT involvement is mainly attributed to GIT dismobility and wide mouth diverticular. GIT involvement in SSc can be also severely debilitating and even life threatening. To our knowledge, the presence of gastrointestinal ...
journal_title:Clinical rheumatology
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doi:10.1007/s10067-006-0264-8
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journal_title:Clinical rheumatology
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journal_title:Clinical rheumatology
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journal_title:Clinical rheumatology
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doi:10.1007/s10067-004-0906-7
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doi:10.1007/s10067-017-3831-2
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02030080
更新日期:1989-06-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-012-2071-8
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journal_title:Clinical rheumatology
pub_type: 杂志文章
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journal_title:Clinical rheumatology
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journal_title:Clinical rheumatology
pub_type: 临床试验,杂志文章
doi:10.1007/BF02207657
更新日期:1991-06-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 杂志文章,随机对照试验
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更新日期:2008-07-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 杂志文章
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journal_title:Clinical rheumatology
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更新日期:2000-01-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02214106
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-018-4129-8
更新日期:2019-01-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 杂志文章,已发布勘误
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journal_title:Clinical rheumatology
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journal_title:Clinical rheumatology
pub_type: 杂志文章
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journal_title:Clinical rheumatology
pub_type: 杂志文章
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更新日期:2017-08-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-016-3281-2
更新日期:2016-10-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02330599
更新日期:1987-12-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-010-1397-3
更新日期:2010-08-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 杂志文章
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journal_title:Clinical rheumatology
pub_type: 杂志文章
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更新日期:2021-01-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02242943
更新日期:1994-09-01 00:00:00