Caeruloplasmin, prealbumin and alpha 2-macroglobulin as potential indices of disease activity in different arthritides.

Abstract:

:Caeruloplasmin (Cp), prealbumin and alpha 2-macroglobulin (alpha 2-M) concentrations in serum were compared in rheumatoid arthritis (RA), osteoarthrosis, ankylosing spondylitis, psoriatic arthritis, Reiter's syndrome, Behçet's syndrome, SLE and normal controls. Cp was significantly elevated (p less than 0.01) in all disease groups except for Reiter's syndrome and SLE. Prealbumin was only significantly depressed (p less than 0.01) in RA. The most notable elevation in alpha 2-macroglobulin occurred in Reiter's syndrome. However, these differences were generally still within the normal range, and hence these proteins are unlikely to offer alternative indices of disease activity suitable for monitoring the the progress of seronegative arthropathies.

journal_name

Clin Rheumatol

journal_title

Clinical rheumatology

authors

Surrall KE,Bird HA,Dixon JS

doi

10.1007/BF02201003

subject

Has Abstract

pub_date

1987-03-01 00:00:00

pages

64-9

issue

1

eissn

0770-3198

issn

1434-9949

journal_volume

6

pub_type

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