Abstract：
:To present the clinical and pathological findings in patients presenting with myositis caused by syphilis. The literature is reviewed, and pathophysiologic factors discussed. A 49-year-old Caucasian heterosexual male with a known history of stable human immunodeficiency virus (HIV) and hepatitis C (HCV) co-infection, developed progressive muscle weakness over 10 weeks. He discontinued his medications; however, he had on-going muscle symptoms. A muscle biopsy was performed, consistent with mild myositis. While on prednisone therapy, he developed panuveitis and vertigo. CSF studies were positive for syphilis (Treponema pallidum). He was started on appropriate antibiotic therapy with complete clinical resolution. This patient presented with myositis and panuveitis as a manifestation of acute onset of syphilis. Syphilis is an uncommon cause of myositis. In patients with HIV and/or HCV, the disease itself and side effects of the medications must be considered. As patients with HIV may have co-infections, syphilis must be considered, especially when unresponsive to traditional management.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Yacyshyn E,Chiowchanwisawakit P,Emery DJ,Jhamandas J,Resch L,Taylor Gdoi
10.1007/s10067-010-1668-zsubject
Has Abstractpub_date
2011-05-01 00:00:00pages
729-33issue
5eissn
0770-3198issn
1434-9949journal_volume
30pub_type
杂志文章,评审abstract：:This study aims to explore the effectiveness of low dose of etanercept (ETN) in patients with ankylosing spondylitis (AS) who achieve a good control of their disease in daily clinical practice. This is a case series of AS patients treated with ETN. According to the judgment of the treating rheumatologist and patient's...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-011-1722-5
更新日期：2011-07-01 00:00:00
abstract：OBJECTIVE:The aim of the study was to evaluate the interrelationship between the micro- and macrovasculature. METHODS:This is a cross-sectional study that examined SSc patients and fibromyalgia (FM) patients as controls. We assessed forearm peripheral vascular status and nailfold capillaroscopy. We evaluated the assoc...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-020-05025-3
更新日期：2020-09-01 00:00:00
abstract：:Two cases of Paget's sarcoma of bone are described. The first one is mainly characterized by the almost simultaneous degeneration of the only two existing locations of the underlying Paget's disease. The second case is one of monostotic Paget's disease of the scapula disclosed by the malignant degeneration. ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02031268
更新日期：1984-12-01 00:00:00
abstract：:We aimed to investigate the possible effects of thioredoxin 1 (Trx1) on the proliferation and apoptosis of rheumatoid arthritis fibroblast-like synoviocytes (RA-FLSs) and elucidate the possible mechanisms involved. We investigated the distribution and expression of Trx1 in synovial tissues from RA and osteoarthritis (...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3832-1
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVE:To test the efficacy of Infliximab, a chimeric monoclonal antibody against TNF-alpha, in the treatment of Takayasu arteritis. MATERIALS AND METHODS:We used infliximab at an initial dose of 3 mg/kg i.v. at weeks 0, 2, 6, and 8 thereafter in combination with methotrexate or azathioprine, to treat four patients...
journal_title：Clinical rheumatology
pub_type： 临床试验,杂志文章
doi：10.1007/s10067-006-0227-0
更新日期：2007-06-01 00:00:00
abstract：:The levels of 63 cytokines, chemokines, and growth factors were measured in the serum of four patients with idiopathic morphea and of one patient with vitamin K1-induced morphea employing a multiplex assay to identify the role of inflammatory/immunologic events in their pathogenesis. Full-thickness skin biopsies of af...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3580-2
更新日期：2017-05-01 00:00:00
abstract：:Polymyositis may occur along with other manifestations of chronic graft vs host disease after allogeneic bone marrow transplantation (BMT). Donor lymphocyte infusion (DLI) could produce durable remissions in relapsed patients with chronic myelogenous leukemia (CML) but it may contribute to the development of polymyosi...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-006-0346-7
更新日期：2007-07-01 00:00:00
abstract：:The aim of this blinded, randomised, multicentre study was to compare the tolerability of aspirin, paracetamol and ibuprofen in common pain resulting from musculoskeletal conditions (MSC) in general practice with patients with other non-MSC pain conditions. Patients took aspirin, paracetamol (both up to 3g daily) or i...
journal_title：Clinical rheumatology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s100670200007
更新日期：2002-02-01 00:00:00
abstract：:The immunoinflammatory pathogenesis of juvenile chronic arthritis (JCA) involves the activation of many pathways including various cytokines. We have evaluated the levels of interleukin(IL)-1, IL-6 and IL-8 in 29 JCA patients. The age range was 1-16 with a mean of 10.1. A disease activity score was developed on the ba...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02247847
更新日期：1997-03-01 00:00:00
abstract：:A case of left brachial plexus compression by an iatrogenic arteriovenous fistula was treated by detachable balloon technique with immediate relief of pain. Good results on paresia were obtained in a few weeks. ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02330599
更新日期：1987-12-01 00:00:00
abstract：:Type B insulin resistance syndrome is characterized by the formation of autoantibodies against insulin receptors, which can cause severe hyperglycemia and insulin resistance. Systemic lupus erythematosus is the most common underlying diseases of the syndrome. This report details our study of a case involving a Chinese...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-012-2098-x
更新日期：2013-02-01 00:00:00
abstract：:The aim of this study was to ascertain whether fibromyalgia patients with positive ANA develop other features of connective tissue disease over 2-4 years' follow-up. Patients attending our clinic with a diagnosis of fibromyalgia were identified. All ANA-positive patients (n = 12) were recruited and matched for age and...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s100670200118
更新日期：2002-11-01 00:00:00
abstract：:A 63-year-old man with hypertrophic pachymeningitis (HP) and an undifferentiated connective tissue disease is described. Combined therapy with prednisolone and azathioprine improved his symptoms. The association between an undifferentiated connective tissue disease and HP is discussed. ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-005-0018-z
更新日期：2006-05-01 00:00:00
abstract：OBJECTIVES:In people with rheumatoid arthritis (RA), mental health problems are common, but often not recognized or treated, contributing to increased morbidity and mortality. Most studies examining the impact of mental health problems in RA have focused on depression. We aimed to determine the association between anxi...
journal_title：Clinical rheumatology
pub_type： 杂志文章,meta分析
doi：10.1007/s10067-019-04900-y
更新日期：2020-05-01 00:00:00
abstract：:HLA B27 and other clinical findings were investigated in 18 Turkish patients with Reiter's syndrome (mean age 35.8 +/- 8.09). Male/female ratio was 2/1. All 18 patients were seronegative, 12 (66.6%) presenting with an asymmetrical oligoarticular arthritis. Radiological sacroiliitis and enthesopathy was found in 9 (50%...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02207965
更新日期：1992-06-01 00:00:00
abstract：:We report a case of bleomycin-induced scleroderma in a 35-year-old woman treated with chemotherapy for Hodgkin's disease. Approximately 6 months after the first chemotherapy cycle, the patient developed skin sclerosis in both arms. The lesion showed no signs of spontaneous clinical amelioration and treatment with ster...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s100670050131
更新日期：1999-01-01 00:00:00
abstract：:Fibrous dysplasia (FD) is a benign skeletal disorder which may affect one or multiple bones. Lesions often involve long bones, ribs, and craniofacial bones and cause pain, fractures, and disfigurement. We describe an adolescent girl with mandibular FD who was successfully treated with bisphosphonates. She presented wi...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-008-0842-z
更新日期：2008-06-01 00:00:00
abstract：:The aim of this study was to evaluate whether dexibuprofen meets the basic requirements of Dutch General Practitioners (GPs) for acceptance as an analgesic in mild to moderate pain. The available GP treatment standards for mild to moderate pain were analysed. If no treatment standard was available, results from two se...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF03342660
更新日期：2001-11-01 00:00:00
abstract：:This study aimed to compare the intraobserver and interobserver reliability of three-dimensional (3D) and two-dimensional (2D) power Doppler ultrasonography (PDUS) and to assess the relationship between 3D PDUS and clinical parameters in patients with rheumatoid arthritis (RA). Bilateral second/third metacarpophalange...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-011-1811-5
更新日期：2012-02-01 00:00:00
abstract：UNLABELLED:There is a paucity of data on the impact of chronic rheumatic diseases on functional disability and overall health-related quality of life (HRQOL) in Africans. MATERIALS AND METHODS:We compared Black South Africans (BSA) with rheumatoid arthritis (RA) (n=50) and systemic lupus erythematosus (SLE) (n=50) to ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-006-0215-4
更新日期：2007-01-01 00:00:00
abstract：:We report an adult case of reflex sympathetic dystrophy. In contrast to the usual findings in adults, three phase bone scintigraphy showed decreased bloodflow and bloodpool with hypofixation on delayed steady state bone scan of the affected lower limb. In spite of various therapeutic attempts severe dystrophy develope...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02208035
更新日期：1991-03-01 00:00:00
abstract：:Joint lavage for knee osteoarthritis is an invasive procedure that can be stressful and painful. We aimed to assess the impact of music therapy on perioperative anxiety, pain and tolerability of the procedure in patients undergoing joint lavage performed with two needles. We randomized all patients diagnosed with knee...
journal_title：Clinical rheumatology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10067-011-1925-9
更新日期：2012-03-01 00:00:00
abstract：:Systemic sclerosis (SSc) is complicated by pulmonary hypertension and right ventricle (RV) failure in approximately 10% of the patients. Factors influencing the reactivity of pulmonary circulation to vasodilators are not established, while the examination of vasoreactivity is important in determining the treatment, be...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-011-1792-4
更新日期：2012-01-01 00:00:00
abstract：OBJECTIVES:The aim of this study is to analyze the prevalence of myositis-specific autoantibodies (MSAs) and to elucidate their associations with clinical features in Chinese patients with polymyositis (PM) and dermatomyositis (DM). METHODS:Twelve subsets of MSAs including anti-Mi-2, anti-TIF1-γ, anti-MDA5, anti-NXP2,...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-019-04503-7
更新日期：2019-08-01 00:00:00
abstract：:Upper lobe fibrobullous disease is a well-known finding in advanced stages of ankylosing spondylitis (AS). In this report, we present a 57-year-old male patient who was diagnosed with a right apical cavitary lesion after coming to us with the complaint of haemoptysis. The patient underwent upper lobe segmentectomy and...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-004-1047-8
更新日期：2005-08-01 00:00:00
abstract：:The aim of this study is to compare effectiveness and safety of Infliximab (INF), Etanercept (ETN), and Adalimumab (ADA) in patients with psoriatic arthritis (PsA) with inadequate response to a previous disease-modifying antirheumatic drug (DMARD). One hundred consecutive PsA patients with inadequate response to a pre...
journal_title：Clinical rheumatology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10067-009-1340-7
更新日期：2010-04-01 00:00:00
abstract：:We describe two cases of rheumatoid arthritis (RA) patients and concomitant hepatitis C virus infection (HCV), treated with cyclosporine A (CsA) and anti-TNF-alpha agents. SGOT/SGPT and HCV-RNA serum levels remained unchanged longer than 1 year of treatment. No side effects were registered. We suggest that combination...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-006-0412-1
更新日期：2007-07-01 00:00:00
abstract：:The aim of the study was to analyse the gynaecologic history of 150 Brazilian patients with systemic sclerosis (SSc) by comparing the outcome of the pregnancies before and after disease onset and in the two clinical variants of SSc, as well as to assess the effects of the pregnancy on the progress of the disease. A re...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s100670050152
更新日期：2000-01-01 00:00:00
abstract：:Chronic whiplash-associated disorders (WAD) remains a challenging condition for clinicians. There is substantial evidence for the presence of various cervical dysfunctions (e.g., increased cervical muscle tone and impaired cervical movement control), but their contribution to the complex clinical picture of subjects w...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-008-1083-x
更新日期：2009-03-01 00:00:00
abstract：:The signalling lymphocyte activation molecule (SLAM) family receptors play important roles in modulating immune responses. Previous studies in murine models and patients have suggested an association of the SLAM family (SLAMF) members with the development of autoimmunity, particularly systemic lupus erythematosus (SLE...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3698-2
更新日期：2018-03-01 00:00:00
