Ro/SS-A and La/SS-B: autoantigens in Sjögren's syndrome?

abstract：:Hyperimmunoglobulinemia D syndrome (HIDS) is newly recognized and resembles familial Mediterranean fever (FMF). It is inherited as an autosomal recessive trait. Mutation of the gene coding for mevalonate kinase is responsible for the disease. The gene is located at chromosome 12q24. The patients initially described we...

journal_title：Clinical rheumatology

authors： Hammoudeh M

更新日期：2005-02-01 00:00:00

abstract：:One of the most important therapeutic goal in hyperhidrosis treatment is to seek for the underlying cause and to tailor the treatment accordingly. A detailed history and prompt physical examination are needed to clarify the etiological factor. In this study, we report a 34-year-old woman with a diagnosis of thoracic o...

journal_title：Clinical rheumatology

authors： Ozdemir O,Ozçakar L

更新日期：2007-08-01 00:00:00

abstract：:B cells in patients with rheumatoid arthritis (RA) are hyperactivated. Although B cell receptor signal transduction may be affected by various response regulators, CD22 plays an important role as a response regulator of B cells. Therefore, we investigated and examined CD22 expression on peripheral blood B cells of pat...

journal_title：Clinical rheumatology

authors： Nakiri Y,Minowa K,Suzuki J,Mitsuo A,Amano H,Morimoto S,Tokano Y,Takasaki Y

更新日期：2007-10-01 00:00:00

abstract：:The objective of this study was to identify predictors for remission or low disease activity (LDA) in established rheumatoid arthritis (RA) at 12 months of anti-TNF-α therapy. We have performed a prospective observational study in 90 consecutive patients with active RA receiving TNF-α inhibitors. Baseline and standard...

journal_title：Clinical rheumatology

authors： Pomirleanu C,Ancuta C,Miu S,Chirieac R

更新日期：2013-05-01 00:00:00

abstract：:Intravenous immunoglobulin (IVIg) is currently used with much enthusiasm for the treatment of many autoimmune diseases, including systemic lupus erythematosus (SLE). Among its various indications, IVIg has also been found to be beneficial in myocarditis, whether or not it is associated with an autoimmune disease (e.g....

journal_title：Clinical rheumatology

authors： Sherer Y,Levy Y,Shoenfeld Y

更新日期：1999-01-01 00:00:00

abstract：:We report a case of hypokalaemic, flaccid quadriparesis with sudden respiratory arrest in a 27-year-old Japanese woman in whom the discovery of distal renal tubular acidosis led to the diagnosis of primary Sjögren's syndrome (SS). Hypokalaemic periodic paralysis as the initial manifestation of primary SS is rare, but ...

journal_title：Clinical rheumatology

authors： Fujimoto T,Shiiki H,Takahi Y,Dohi K

更新日期：2001-01-01 00:00:00

abstract：:We investigated the clinical characteristics, management modalities, and outcomes in patients with relapsing polychondritis (RP) with airway involvement. The medical records of RP patients with airway involvement seen at Samsung Medical Center from August 2004 to December 2011 were collected. The clinical manifestatio...

journal_title：Clinical rheumatology

authors： Hong G,Kim H

更新日期：2013-09-01 00:00:00

abstract：:To validate the Quality of Life-Rheumatoid Arthritis Scale II (QOL-RA II) in an Argentinean cohort of patients with rheumatoid arthritis (RA). Patients ≥ 18 years old, with a diagnosis of RA according to ACR-EULAR 2010 criteria, were included in a cross-sectional study. Sociodemographic data, comorbidities, RA charact...

journal_title：Clinical rheumatology

authors： Isnardi CA,Schneeberger EE,Capelusnik D,de Los Ángeles Correa M,Lim R,Hu M,Tapia MJ,Kerzberg E,Blanco E,Benavidez FL,Gonzales Lucero L,Barbaglia AL,Bazzarelli M,Ficco HM,Pérez S,Hartvig C,Salcedo M,Citera G

更新日期：2020-11-01 00:00:00

abstract：:Anti-nucleosome antibodies, which recognise conformational epitopes consisting of histone and DNA in chromatin, have been described in autoimmune diseases. In this study, an attempt was made to isolate anti-nucleosome antibodies from the anti-DNA-depleted plasma IgG of two lupus patients either with or without nephrit...

journal_title：Clinical rheumatology

authors： Suenaga R,Mitamura K,Abdou NI

更新日期：1998-01-01 00:00:00

abstract：:Intercellular adhesion molecule-1 (ICAM-1) is a membrane bound molecule that plays an important role in the pathogenic inflammatory responses observed in vasculitis. The aim of this study was to determine whether levels of soluble ICAM-1 sICAM-1) shedding into the circulation reflect the vascular injury found in nailf...

journal_title：Clinical rheumatology

authors： Kuryliszyn-Moskal A,Bernacka K,Klimiuk PA

更新日期：1996-07-01 00:00:00

abstract：:In sera of patients with systemic lupus erythematosus (SLE) a wide variety of antibodies against nuclear antigens can be found, including antibodies to nucleic acids, histones and non-histone nuclear proteins. Among these, antibodies to double stranded DNA (dsDNA) appear to be mainly restricted to SLE. Yet, in daily p...

journal_title：Clinical rheumatology

authors： Swaak T,Smeenk R

更新日期：1987-06-01 00:00:00

abstract：:As a class, tumor necrosis factor (TNF)-alpha inhibitors have provided clinicians significant control over chronic inflammatory diseases. With their widespread use has come the emergence of new side effects such as the reactivation of latent infections. One such infection that may reactivate is the hepatitis B virus (...

journal_title：Clinical rheumatology

authors： Carroll MB,Forgione MA

更新日期：2010-09-01 00:00:00

abstract：:Antibodies to beta(2)-glycoprotein I (anti-beta(2)-GPI) have been reported to have stronger association with clinical antiphospholipid syndrome (APS) than anticardiolipin antibodies (aCL) and lupus anticoagulant (LAC). We investigated the sensitivity and specificity of ELISA for anti-beta(2)-GPI in Thai systemic lupus...

journal_title：Clinical rheumatology

authors： Parkpian V,Verasertniyom O,Vanichapuntu M,Totemchokchyakarn K,Nantiruj K,Pisitkul P,Angchaisuksiri P,Archararit N,Rachakom B,Ayurachai K,Janwityanujit S

更新日期：2007-10-01 00:00:00

abstract：:Treatment with methotrexate (MTX) is well established in rheumatoid arthritis (RA), but dosing remains arbitrary as studies on the effect of different dosing schedules are lacking. In a randomised crossover design of 20 patients with RA, the effect of low (2.5mg) oral daily doses of MTX (15 mg weekly) was compared to ...

journal_title：Clinical rheumatology

authors： Seideman P

更新日期：1993-06-01 00:00:00

abstract：:The signalling lymphocyte activation molecule (SLAM) family receptors play important roles in modulating immune responses. Previous studies in murine models and patients have suggested an association of the SLAM family (SLAMF) members with the development of autoimmunity, particularly systemic lupus erythematosus (SLE...

journal_title：Clinical rheumatology

authors： Mak A,Thornhill SI,Lee HY,Lee B,Poidinger M,Connolly JE,Fairhurst AM

更新日期：2018-03-01 00:00:00

abstract：:Heterogenous population of cells, including macrophages, synoviocytes and lymphocytes play important roles in the immunopathogenesis of rheumatoid arthritis (RA). T cells, however, seem to be a common thread throughout the disease process. In inhibiting T lymphocytes, cyclosporin A presents a more selective form of th...

journal_title：Clinical rheumatology

authors： Bentin J

更新日期：1995-09-01 00:00:00

abstract：:The objective of the study was to analyze the prognostic factors of radiographic progression in a series of patients with early rheumatoid arthritis (RA) after 2 years of therapy with a structured algorithm using disease-modifying antirheumatic drugs (DMARDs) and very low doses of oral glucocorticoids. One hundred and...

journal_title：Clinical rheumatology

authors： Sanmartí R,Gómez-Centeno A,Ercilla G,Larrosa M,Viñas O,Vazquez I,Gómez-Puerta JA,Gratacós J,Salvador G,Cañete JD

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVES:To assess the efficacy and safety of the commonly used urate-lowering therapies (ULTs): febuxostat, allopurinol, and lesinurad in hyperuricemic patients with gout. METHODS:We included all randomized controlled trials (RCTs) that compared ULTs with placebo or head to head. The primary efficacy endpoint was t...

journal_title：Clinical rheumatology

authors： Fan M,Liu J,Zhao B,Wu X,Li X,Gu J,Schlesinger N

更新日期：2021-02-01 00:00:00

abstract：:The objectives of this study are to assess the levels of serum Interleukin-35 (IL-35) in patients with idiopathic inflammatory myopathies (IIMs) and to evaluate the association between IL-35 levels and IIM-related features. Serum IL-35 was detected in 76 patients with dermatomyositis (DM), 28 patients with polymyositi...

journal_title：Clinical rheumatology

authors： Yin L,Ge Y,Yang H,Peng Q,Lu X,Zhang Y,Wang G

更新日期：2016-11-01 00:00:00

abstract：:The objective of this work was to study the clinical and serological profiles of rheumatoid arthritis in Burkina Faso (West Africa). It is a cross-sectional study conducted from March 2006 to February 2009 in the Internal Medicine Department of the University Hospital Yalgado Ouedraogo. All patients seen in the rheuma...

journal_title：Clinical rheumatology

authors： Ouédraogo DD,Singbo J,Diallo O,Sawadogo SA,Tiéno H,Drabo YJ

更新日期：2011-12-01 00:00:00

abstract：:Objectives of this study were to examine work disability (WD) and its leading causes in incident SLE patients. Data were derived from the Finnish nationwide registries to identify all non-retired, 18 to 64-year-old incident SLE patients between 2000 and 2007. Sick benefits and WD pensions and the causes for them were ...

journal_title：Clinical rheumatology

authors： Elfving P,Puolakka K,Rantalaiho V,Kautiainen H,Virta LJ,Kaipiainen-Seppänen O

更新日期：2018-05-01 00:00:00

abstract：:Psoriatic arthritis (PsA) is a chronic T cell-mediated inflammatory spondyloarthropathy affecting 10-40 % of psoriasis (PSO) patients (0.3-1.0 % of the general population). Recent epidemiological studies have shown an increased prevalence of cardiovascular (CV) risk factors and/or morbidity among PSO or PsA patients a...

journal_title：Clinical rheumatology

authors： Khraishi M,Aslanov R,Rampakakis E,Pollock C,Sampalis JS

更新日期：2014-01-01 00:00:00

abstract：:Physical therapy and exercise (recreational activity) are the cornerstones of non-pharmacologic therapy in axial spondyloarthritis (AxSpA) [1, 2]. These are components of physical activity, though physical activity is made up of activities beyond these and also include occupational activity. Not all activities in AxSp...

journal_title：Clinical rheumatology

authors： Gensler LS

更新日期：2016-06-01 00:00:00

abstract：:Cricoarytenoid arthritis is a frequent complication of rheumatoid arthritis. In most cases it is an insidious, progressive disorder which does not produce early symptoms. A bilateral fixation can lead to a considerable stenosis; exertional dyspnoea, however, may not be noted because mobility of most patients is restri...

journal_title：Clinical rheumatology

authors： Ten Holter JB,Van Buchem FL,Van Beusekom HJ

更新日期：1988-06-01 00:00:00

abstract：:The tendency of patients with DISH towards obesity or an adult onset of diabetes has been reflected in marked hyperinsulinaemia following glucose challenge. It is hypothesized that insulin at prolonged and high physiologic levels promotes new bone growth, particularly in the entheseal regions. These areas are also sub...

journal_title：Clinical rheumatology

authors： Littlejohn GO

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVE:To investigate the clinical characteristics, laboratory features, and treatment outcomes of Thai patients compared between those with necrotizing autoimmune myopathy (NAM) and those with other idiopathic inflammatory myopathies (IIMs) or non-NAM. METHODS:This multicenter case-control study included patients ...

journal_title：Clinical rheumatology

authors： Yongchairat K,Tanboon J,Waisayarat J,Narongroeknawin P,Chevaisrakul P,Dejthevaporn C,Katchamart W

更新日期：2019-12-01 00:00:00

abstract：:The aim of this study was to investigate the clinical features, risk factors, and outcomes of septic arthritis in patients on maintenance hemodialysis (HD). We systematically reviewed medical records of 16 HD patients with septic arthritis admitted to our hospital from April 2008 to April 2018. A total of 16 HD in pat...

journal_title：Clinical rheumatology

authors： Zhang J,You X

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:To test the psychometric properties of the United Kingdom's Commissioning for Quality in Rheumatoid Arthritis Patient-Reported Experience Measure (CQRA-PREM) in patients with spondyloarthritis (SpA) and rheumatoid arthritis (RA) and to implement this questionnaire in daily practice in the Netherlands. METHO...

journal_title：Clinical rheumatology

authors： Beckers E,Webers C,Boonen A,Ten Klooster PM,Vonkeman HE,van Tubergen A

更新日期：2020-10-01 00:00:00

abstract：:Microwave thermography is the technique of measuring natural thermal radiation from body tissues of clinical interest. It is safe, requires no control of environmental conditions and exposes the patient to no ionising radiation. In this study, we found that microwave thermography of the knee joints showed weak correla...

journal_title：Clinical rheumatology

authors： MacDonald AG,Land DV,Sturrock RD

更新日期：1994-12-01 00:00:00

abstract：:We aimed to evaluate the presence of peripheral antineutrophil cytoplasmic antibodies (p-ANCA) and cytoplasmic antineutrophil cytoplasmic antibodies (c-ANCA) in children with SLE and to correlate its association of laboratory findings. Twenty-one children with SLE were studied. Serum samples in patients were tested by...

journal_title：Clinical rheumatology

authors： Bakkaloglu A,Topaloglu R,Saatçi U,Ozdemir S,Ozen S,Başsoy Y,Beşbaş N

更新日期：1998-01-01 00:00:00