A 'made in one piece' skeleton in a 22-year-old man suffering from sickle cell anaemia.

abstract：:Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disorder. Renal involvement has the worst prognosis. However, renal cortical necrosis is extremely unusual in SLE. In this case report, we describe the autopsy findings in a young female patient with SLE presenting with renal failure. At autopsy, there w...

journal_title：Clinical rheumatology

authors： Uppin MS,Rajasekhar L,Swetha H,Srinivasan VR,Prayaga AK

更新日期：2010-07-01 00:00:00

abstract：:Clinically amyopathic dermatomyositis (CADM) is a unique subset of dermatomyositis, showing a high incidence of lung involvements. The aim of this study is to identify risk factors, other than melanoma differentiation-associated protein (MDA)-5, for developing rapidly progressive-interstitial lung disease (RP-ILD) in ...

journal_title：Clinical rheumatology

authors： Xu Y,Yang CS,Li YJ,Liu XD,Wang JN,Zhao Q,Xiao WG,Yang PT

更新日期：2016-01-01 00:00:00

abstract：:We described a 21-year-old woman with a diagnosis of Sjögren syndrome that came for consultation with a localized mass over her left arm of fast growth. Lab results were normal; a Doppler ultrasound showed the presence of partial thrombosis in the left axillary vein; a magnetic resonance imaging showed edema on the bi...

journal_title：Clinical rheumatology

authors： Roverano S,Ortiz A,Paira S

更新日期：2016-04-01 00:00:00

abstract：:The aim of the is study is to examine the role of serum substance P (SP) levels as a simple biomarker for rheumatoid arthritis (RA) disease activity, its correlation with other markers of disease activity, and with selected clinical parameters. The study comprised 90 RA patients and 24 healthy controls. RA activity wa...

journal_title：Clinical rheumatology

authors： Barbosa-Cobos RE,Lugo-Zamudio G,Flores-Estrada J,Becerril-Mendoza LT,Rodríguez-Henríquez P,Torres-González R,Moreno-Eutimio MA,Ramirez-Bello J,Moreno J

更新日期：2018-04-01 00:00:00

abstract：:The study aimed to determine the serum level of glucocorticoid-induced tumor necrosis factor receptor family-related protein ligand (GITRL) in patients with rheumatoid arthritis (RA) and investigate its clinical significance. GITRL levels were measured by enzyme-linked immunosorbent assay (ELISA) in 88 RA patients, 20...

journal_title：Clinical rheumatology

authors： Li L,Wen W,Jia R,Li Y,Liu X,Sun X,Li Z

更新日期：2016-09-01 00:00:00

abstract：:HLA-II molecules are critical in triggering human immune response, especially in activating CD4+ T cells. HLA-DP, belonging to HLA-II molecules, draws increasing attention for its role in presentation of viral antigen and autoantigen to T cells. Researches reported single nucleotide polymorphism (SNP) of HLA-DP associ...

journal_title：Clinical rheumatology

authors： Huang Z,Niu Q,Yang B,Zhang J,Yang M,Xu H,Cai B,Hu J,Wu Y,Wang L

更新日期：2018-07-01 00:00:00

abstract：:Tumour necrosis factor alpha (TNF alpha) and interleukin-2 (IL-2) are potential immunological mediators of pathogenetic changes in rheumatoid arthritis. We measured the concentrations of TNF alpha and IL-2 in plasma from 2 groups of patients suffering from rheumatoid arthritis (RA). One group had high and one had low ...

journal_title：Clinical rheumatology

authors： Espersen GT,Vestergaard M,Ernst E,Grunnet N

更新日期：1991-12-01 00:00:00

abstract：:Anaerobic bacteria are uncommon pathogens in septic arthritis. We report a case of pyarthrosis of the right hip caused by Fusobacterium nucleatum, following a transient synovitis in an otherwise healthy boy. There are only a few cases involving this species described in the literature. This report illustrates the diff...

journal_title：Clinical rheumatology

authors： Chryssagi AM,Brusselmans CB,Rombouts JJ

更新日期：2001-01-01 00:00:00

abstract：:Autonomic nervous system (ANS) involvement has been studied in systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, Sjogren's syndrome, and ankylosing spondylitis but still has not been studied in psoriatic arthritis (PsA). The aim of this study was to investigate the prevalence and the nature of au...

journal_title：Clinical rheumatology

authors： Syngle A,Verma I,Garg N,Krishan P

更新日期：2013-07-01 00:00:00

abstract：:We report one case of non-Hodgkin lymphoma in a patient, with a 30-year history of rheumatoid arthritis, taking low dose methotrexate weekly over a 10-month period. The mild immunosuppression that occurs with methotrexate therapy probably places patients with rheumatoid arthritis at added risk of developing lymphoprol...

journal_title：Clinical rheumatology

authors： Taillan B,Garnier G,Castanet J,Ferrari E,Pesce A,Dujardin P

更新日期：1993-03-01 00:00:00

abstract：:Identification of patients with exposure to viral hepatitis is an important part of the care of patients with inflammatory arthritis. This study was conducted to assess the extent of hepatitis B and C screening, and the prevalence of viral hepatitis in a cohort of patients with established rheumatoid arthritis (RA). T...

journal_title：Clinical rheumatology

authors： Conway R,Doran MF,O'Shea FD,Crowley B,Cunnane G

更新日期：2014-12-01 00:00:00

abstract：:Gout is a disease with acute and/or chronic inflammation and tissue damage induced by the precipitation of monosodium urate crystal (MSU) crystals in bone joints, kidneys, and subcutaneous sites. In recent years, with the continuous research on gout animal models and patient clinical investigations, the mechanism of i...

journal_title：Clinical rheumatology

authors： Wu M,Tian Y,Wang Q,Guo C

更新日期：2020-10-01 00:00:00

abstract：:Takayasu's arteritis (TA) is a rare vasculitis that affects the aorta and its primary branches. Heterogeneous clinical manifestations have been described in different geographical areas. We aimed to evaluate demographic, clinical, and angiographic features and the outcome in 16 TA patients who were followed in a singl...

journal_title：Clinical rheumatology

authors： Petrovic-Rackov L,Pejnovic N,Jevtic M,Damjanov N

更新日期：2009-02-01 00:00:00

abstract：:The involvement of brain-derived neurotrophic factor (BDNF) in rheumatoid arthritis (RA) is largely unknown. The distribution of BDNF and its associated receptors, TrkB and p75, in the synovial tissue of patients with RA was examined and contrasted with that in patients with osteoarthritis (OA). Additionally, levels o...

journal_title：Clinical rheumatology

authors： Grimsholm O,Rantapää-Dahlqvist S,Dalén T,Forsgren S

更新日期：2008-10-01 00:00:00

abstract：:Pulse prednisolone hemisuccinate therapy (500 mg given intravenously on three occasions over two weeks) has been combined with either intramuscular sodium aurothiomalate or azathioprine in an assessment of 30 patients with rheumatoid arthritis. Significant improvement in a variety of clinical and biochemical assessmen...

journal_title：Clinical rheumatology

authors： Häntzschel H,Otto W,Arnold S,Seidel W,Krüger W,Winiecki P,Bird HA,Dixon JS,Astbury G,Wright V

更新日期：1988-06-01 00:00:00

abstract：:Gastrointestinal tract (GIT) is the most common organ system involved in systemic sclerosis (SSc). GIT involvement is mainly attributed to GIT dismobility and wide mouth diverticular. GIT involvement in SSc can be also severely debilitating and even life threatening. To our knowledge, the presence of gastrointestinal ...

journal_title：Clinical rheumatology

authors： Plastiras SC,Tzivras M,Vlachoyiannopoulos PG

更新日期：2007-06-01 00:00:00

abstract：:We report a case of bleomycin-induced scleroderma in a 35-year-old woman treated with chemotherapy for Hodgkin's disease. Approximately 6 months after the first chemotherapy cycle, the patient developed skin sclerosis in both arms. The lesion showed no signs of spontaneous clinical amelioration and treatment with ster...

journal_title：Clinical rheumatology

authors： Passiu G,Cauli A,Atzeni F,Aledda M,Dessole G,Sanna G,Nurchis P,Vacca A,Garau P,Laudadio M,Mathieu A

更新日期：1999-01-01 00:00:00

abstract：:It is commonly believed that infliximab-induced anticardiolipin antibody belongs to the IgM subclass but not the IgG subclass and that the IgM subclass could not produce clinical symptoms. However, we had a patient with scleroderma overlap/rheumatoid arthritis who developed thrombocytopenia associated with the appeara...

journal_title：Clinical rheumatology

authors： Hamaguchi M,Kawahito Y,Ishino H,Yoshida M,Yoshikawa T

更新日期：2007-06-01 00:00:00

abstract：:The aim of this study was to assess the role of oxidative stress in the pathogenesis of Henoch-Schönlein purpura (HSP) vasculitis. The activities of catalase (CAT), arylesterase (ARYL), and paraoxonase (PON) as antioxidant enzymes and serum malondialdehyde (MDA) level as an indicator of lipid peroxidation, together wi...

journal_title：Clinical rheumatology

authors： Ece A,Kelekçi S,Kocamaz H,Hekimoğlu A,Balik H,Yolbaş I,Erel O

更新日期：2008-02-01 00:00:00

abstract：:To study the clinical characteristics of autoimmune rheumatic disease-related organizing pneumonia (AIRD-OP), the clinical presentation, radiological findings, treatment, and outcome of AIRD-OP patients were analyzed, in comparison with patients with cryptogenic organizing pneumonia (COP). A total of 131 OP patients w...

journal_title：Clinical rheumatology

authors： Dong X,Zheng Y,Wang L,Chen WH,Zhang YG,Fu Q

更新日期：2018-04-01 00:00:00

abstract：:Extensive subcutaneous and muscular calcification developed in a patient having adult-onset dermatopolymyositis (DM-PM) with an 'overlap' connective tissue disease. We wish to emphasize the rarity of calcification in adult onset DM-PM, which is contrary to the generally held impression. ...

journal_title：Clinical rheumatology

authors： Cohen MG,Nash P,Webb J

更新日期：1986-12-01 00:00:00

abstract：:Our aim was to determine reasons for admission, the prevalence and spectrum of infections, and the outcomes in a multiethnic cohort of hospitalized systemic lupus erythematosus (SLE) patients in Durban, South Africa. We reviewed the records of hospitalized SLE patients seen over a 79-month period; the demographic data...

journal_title：Clinical rheumatology

authors： Dubula T,Mody GM

更新日期：2015-03-01 00:00:00

abstract：:It has recently been claimed that some of the symptoms in patients with Behçet's disease (BD) can be activated after the patient has stopped smoking. In this study we investigated the effect of smoking on the symptoms of Behçet's disease. Fifty asymptomatic current smokers (CS) who promised to stop smoking (group 1) a...

journal_title：Clinical rheumatology

authors： Soy M,Erken E,Konca K,Ozbek S

更新日期：2000-01-01 00:00:00

abstract：:Knee osteoarthritis (KOA) is a common degenerative joint disease causing pain, stiffness, reduced motion, swelling, crepitus, and disability. Several inflammatory markers and cartilage degradation products can be used as biomarkers in OA. The key factors of bone metabolism in normal joint bone, dickkopf-1 (DKK1) and o...

journal_title：Clinical rheumatology

authors： Min S,Wang C,Lu W,Xu Z,Shi D,Chen D,Teng H,Jiang Q

更新日期：2017-10-01 00:00:00

abstract：:Muscle pain and weakness in a rheumatoid arthritis (RA) patient has a broad differential, and myositis should be considered early in the disease course as serious limb and life-threatening sequelae may occur. A 55-year-old woman with a past medical history of methotrexate-controlled RA presented with right leg pain fo...

journal_title：Clinical rheumatology

authors： Jo D,Pompa T,Khalil A,Kong F,Wetz R,Goldstein M

更新日期：2015-10-01 00:00:00

abstract：:Catastrophic anti-phospholipid syndrome (CAPS) is a medical emergency characterized by thromboses of multiple small vessels of internal organs and the brain. Herein we present a patient with primary anti-phospholipid syndrome who developed CAPS manifested by hepatic, renal and splenic artery thromboses, as well as cer...

journal_title：Clinical rheumatology

authors： Zeller L,Almog Y,Tomer A,Sukenik S,Abu-Shakra M

更新日期：2006-05-01 00:00:00

abstract：:Adult onset Still's disease (AOSD) is an inflammatory disease of unknown etiology, characterized by spiking fever, evanescent salmon pink maculopapular rash, arthritis, and leukocytosis with neutrophilia. Malignant lymphoma is one of the most important differential diagnoses of AOSD. AOSD has been reported as one of p...

journal_title：Clinical rheumatology

authors： Ahn JK,Oh JM,Lee J,Kim SW,Cha HS,Koh EM

更新日期：2010-02-01 00:00:00

abstract：:We aimed to investigate the possible effects of thioredoxin 1 (Trx1) on the proliferation and apoptosis of rheumatoid arthritis fibroblast-like synoviocytes (RA-FLSs) and elucidate the possible mechanisms involved. We investigated the distribution and expression of Trx1 in synovial tissues from RA and osteoarthritis (...

journal_title：Clinical rheumatology

authors： Lu T,Zong M,Fan S,Lu Y,Yu S,Fan L

更新日期：2018-01-01 00:00:00

abstract：:Bacteroides fragilis is a rare cause of septic arthritis. Most patients with B. fragilis septic arthritis have a chronic joint disease, particularly rheumatoid arthritis, and sources of infection are lesions of the gastrointestinal tract and the skin. We report a 69-year-old male, who developed B. fragilis septic arth...

journal_title：Clinical rheumatology

authors： Borer A,Weber G,Riesenberg K,Schlaeffer F,Horowitz J

更新日期：1997-11-01 00:00:00

abstract：:We reported a series of ten patients with lupus nephritis (five patients in the relapse phase and five in the remission phase) and measured the macrophage migration inhibitory factor (MIF), an important pro-inflammatory cytokine with probable role in the pathogenesis of many inflammatory diseases, in their urine sampl...

journal_title：Clinical rheumatology

authors： Otukesh H,Chalian M,Hoseini R,Chalian H,Hooman N,Bedayat A,Yazdi RS,Sabaghi S,Mahdavi S

更新日期：2007-12-01 00:00:00