Abstract：
:The intestinal immune system has to strike a delicate balance between initiating inflammatory responses against invading bacterial pathogens and avoiding their induction against microbiota colonizing the lumen. Adequate inflammatory responses against bacterial invasion result in the lumenal secretion of antimicrobial peptides, as well as the release of cytokines in tissue that recruit and activate phagocytes. However, pathogens have evolved to utilize these environmental changes in the inflamed intestine to promote colonization. This review focuses on the costs and benefits of intestinal inflammation and the fine interplay between the host, its microbiota, and enteric pathogens.
journal_name
Cell Host Microbejournal_title
Cell host & microbeauthors
Winter SE,Keestra AM,Tsolis RM,Bäumler AJdoi
10.1016/j.chom.2010.06.003subject
Has Abstractpub_date
2010-07-22 00:00:00pages
36-43issue
1eissn
1931-3128issn
1934-6069pii
S1931-3128(10)00206-4journal_volume
8pub_type
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