Abstract:
Introduction:Introduction: glutamine (GLN), the most abundant non-essential amino acid in the plasma, tends to be rapidly depleted in cells in situations of metabolic stress. Some studies have demonstrated the benefits of GLN supplementation on mortality, infection, and length of hospital stay. The objective of this review was to analyze whether parenteral supplementation with GLN has any relevant effect in critically ill surgical patients. Methods: based on a systematic database search, randomized clinical trials (RCTs) published since 1985 were included if they had evaluated the effect of parenteral GLN supplementation in critical surgical patients. The statistical analysis was performed using the RevMan 5.3 software. Results: seven RCTs were eligible for the meta-analysis. Parenteral glutamine supplementation was associated with a non-significant 24 % reduction in mortality (RR = 0.76; 95 % CI: 0.50-1.15). Infections were significantly reduced (RR = 0.60; 95 % CI: 0.45-0.80), and length of hospital stay was 4.09 days shorter (95 % CI: -6.71 to -1.46). Conclusion: parenteral GLN usage in critical surgical patients seems to decrease infection and length of hospital stay, but we could not demonstrate a significant reduction in mortality. Introducción:Introducción: la glutamina (GLN), el aminoácido no esencial más abundante en el plasma, tiende a agotarse rápidamente en las células en situaciones de estrés metabólico. Algunos estudios han demostrado beneficios de la suplementación con GLN en términos de reducción de la mortalidad, las infecciones y la duración de la hospitalización. El objetivo de esta revisión es analizar si la suplementación parenteral de GLN tiene algún efecto relevante para los pacientes quirúrgicos en estado crítico. Métodos: basado en una búsqueda sistemática de bases de datos, se incluyeron ensayos clínicos aleatorizados (ECA) publicados desde 1985 si estos habían evaluado el efecto de la suplementación parenteral de GLN en pacientes quirúrgicos críticos. El análisis estadístico se realizó utilizando el software RevMan 5.3. Resultados: siete ECA fueron elegibles para el metaanálisis. La suplementación parenteral de glutamina se asoció a una reducción no significativa del 24 % en la mortalidad (RR = 0,76; IC 95 %: 0,50-1,15). Las infecciones se redujeron significativamente (RR = 0,60; IC 95 %: 0,45-0,80) y la duración de la estancia de hospitalización fue 4,09 días menor (IC 95 %: -6,71 a -1,46). Conclusión: El uso de GLN parenteral en pacientes quirúrgicos críticos parece disminuir las infecciones y la duración de la estancia hospitalaria, pero no pudimos demostrar una reducción significativa de la mortalidad.
journal_name
Nutr Hospjournal_title
Nutricion hospitalariaauthors
Pimentel RFW,Fernandes SLdoi
10.20960/nh.02949subject
Has Abstractpub_date
2020-07-13 00:00:00pages
616-621issue
3eissn
0212-1611issn
1699-5198journal_volume
34pub_type
杂志文章abstract::A clinical study on the incidence of malnutrition among hospital patients with digestive system surgical disease is presented. Eighty-one patients were admitted into this trial and underwent preoperative nutritional assessment, which permitted classifying the type and intensity of malnutrition, in order to develop the...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:1990-05-01 00:00:00
abstract:INTRODUCTION:A decline in memory and cognitive function is considered to be a normal consequence of aging. Polyunsaturated omega-3 fatty acids are increasingly proposed as dietary supplements with the ability to reduce the risk of cognitive decline, including Alzheimer's disease (AD). AIM:To study the effect of omega-...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.3305/nh.2014.30.3.7632
更新日期:2014-09-01 00:00:00
abstract::Cereals are considered a basic food. Through the development of cooking, the human being has produced high- gluten-content food, so that it could make the most of its nutritional properties. Wheat is becoming one of the key elements of the Mediterranean diet. Amongst gluten- intake-related pathologies- gluten is prese...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.3305/nh.2015.31.6.8984
更新日期:2015-06-01 00:00:00
abstract:OBJECTIVES:To evaluate the organoleptic characteristics of two specific nutritional supplements for diabetes (Glucerna SR and Resource Suport) and compare them. SETTING:An evaluation was made of 456 patients with Type 2 diabetes (most of them receiving OADs or insulin) from 34 centers. They were non-smoking elderly pa...
journal_title:Nutricion hospitalaria
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2004-09-01 00:00:00
abstract:INTRODUCTION:Stature is an important variable in several indices of nutritional status that are applicable to elderly persons. However, stature is difficult or impossible to measure in elderly because they are often unable to maintain the standing position. A alternative is the use of estimated height from measurements...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.31.2.7618
更新日期:2014-10-16 00:00:00
abstract::Objective: To estimate the prevalence of chronic obstructive pulmonary disease (COPD) phenotypes in the province of Leon. Methods: Multicenter epidemiological cross-sectional study (30 health centers in the province of Leon). It included patients older than 35 years diagnosed and treated for COPD. Study variables: ag...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,多中心研究
doi:10.20960/nh.995
更新日期:2017-02-01 00:00:00
abstract:Introduction:Introduction: currently, it is important to determine whether food frequency questionnaires (FFQ) are valid tools to collect information on usual diet in children. Objective: we evaluated the reproducibility and validity of the semi-quantitative FFQ used in a Spanish cohort of children aged 4-7 years. Meth...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.03003
更新日期:2020-08-27 00:00:00
abstract:INTRODUCTION:Few studies have evaluated the efficacy and reliability of weight loss-focussed prepared food dishes in obese post-menopausal women. OBJECTIVE:To compare the efficacy of a weight loss programme based on a balanced hypocaloric diet using prepared dishes* with that of a similar programme based on standard c...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.1590/S0212-16112012000200038
更新日期:2012-03-01 00:00:00
abstract:Introduction:Introduction: chronic kidney disease contributes to decreased muscle strength and physical function through a decrease in muscle mass. Current evidence suggests that hemodialysis can accentuate this complication, as well as lead to deterioration of the patient's overall health. The aim of this study is to ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.03076
更新日期:2020-10-21 00:00:00
abstract::Home enteral nutrition (HEN) is a type of enteral nutrition (EN) which is becoming progressively more widespread in pediatrics due to the benefits it affords to patients, their families and to reducing hospital costs. However, the true extent of its use is unknown in Spain as the data-base set up for this purpose is s...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2010-09-01 00:00:00
abstract::The term "conditionally essential" (or semi-essential), initially applied to amino acids, has been generalized to other nutrients. A conditionally essential nutrient is a compound usually produced in adequate amounts by endogenous synthesis but that is exogenously required under certain circumstances. Thus, arginine, ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:
更新日期:2006-05-01 00:00:00
abstract::A large number of recreational and elite athletes use nutritional supplements in hopes of improving performance. These aids can be costly and potentially harmful, and the advertised ergogenic gains are often based on little or no scientific evidence. Due to the lack of regulation of the dietary supplement industry, an...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:residents are vulnerable to suffer of dehydration due to physiological changes and the physical and cognitive limitations. AIM:to handle this situation, it has been decided to evaluate the interventions which are carried out for the management of dehydration and low fluid intake in older people living in nu...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.20960/nh.1885
更新日期:2018-12-03 00:00:00
abstract:Introduction:Aging is associated, per se, with the loss of functional reserve of different organs and systems, a greater risk of vulnerability and frailty, sarcopenia and malnutrition, a reality that is extended to cancer patients. There are several factors that are associated with malnutrition in the elderly individua...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.02986
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:to identify what effect causes enteral nutrition on nutritional status of cancer. METHOD:a search was performed using the keywords "Cancer" AND "Enteral Nutrition" AND "Supplementation" in four document databases: Pubmed, EBSCO, ProQuest, and Web of Science. INCLUSION CRITERIA:age of the sample, major than ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,meta分析,评审
doi:10.3305/nh.2015.32.4.9227
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:To evaluate body composition differences between children that were born small (SGA) or large for gestational age (LGA) compared with their counterparts born adequate for gestational age (AGA). METHODS:Body composition was assessed in 124 healthy Caucasian children (50% girls) aged 6-10, classified according...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.1590/S0212-16112011000500008
更新日期:2011-09-01 00:00:00
abstract::The objective of this work was to determine whether the increase in serum GH, IGF1, glucose and insulin levels caused by the administration of hGH modifies the normal response of cholesterol and lipoproteins to surgical aggression. A prospective, randomized, and double blind study is carried out in 28 patients operate...
journal_title:Nutricion hospitalaria
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1998-07-01 00:00:00
abstract:Introduction:Introduction: promoting healthy lifestyles already from the pediatric age for prevention of diseases at a short, mid and long-term is compulsory worldwide. Objectives: to know eating patterns and dietary habits, physical activity and sedentary behaviours in urban Spanish children aged one to nine years old...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.03348
更新日期:2021-01-13 00:00:00
abstract:UNLABELLED:Head and neck cancer patients are frecuently heavy alcohol drinkers. The aim of this study is to determine the impact of alcohol intake on nutritional status and the impact in prognoses. PATIENTS AND METHODS:Fifty patients with oral and pharyngolaryngeal carcinomas were prospective studied in a control-case...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2004-11-01 00:00:00
abstract::As part of the nutritional survey of the Canary Islands (ENCA-1998), the concentrations in serum of Na, K, Ca and P were determined in 395 individuals representing the population of the Canary Islands. The concentrations were found to be within the reference intervals described for the healthy population. Differences ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2002-07-01 00:00:00
abstract::Over the last few years, the colon has come to be considered more and more as a central digestive organ. This is where bacterial fermentation takes place to eliminate the substrates, mostly carbohydrates, that have avoided digestion by human enzymes within the small intestine. Of these, fibre plays a prominent role. A...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:The intestinal dysbiosis is common in chronic liver disease and can induce to inflammatory responses and mediate the collagen deposition in the liver. AIM:To evaluate the probiotic Lactobacillus rhamnosus GG (LGG) for the treatment of liver fibrosis in a model of chronic cholestatic liver disease in rats. ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.626
更新日期:2017-06-05 00:00:00
abstract:INTRODUCTION:southern European, Middle Eastern, and North African countries bordering the Mediterranean share dietary habits characterized by moderation and a variety of foods, notably fruit and vegetables. These customs are becoming modified due to social and economic changes. An adequate intake of water and other dri...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.32.6.9892
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:the incidence of hospital undernutrition and its consequences for both the patient and the hospital has demanded procedures that ensure the delivery of good-quality hospital nutritional care. On the basis of literature reports, this study aimed to build a hospital nutritional care propositions tha...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.32.3.9307
更新日期:2015-09-01 00:00:00
abstract:Introduction:Introduction: parenteral nutrition (PN) is commonly used as a nutritional support option. It may cause complications, partly due to a central venous access. Chylothorax is an accumulation of lymphatic fluid in the pleural space. Case report: a 57-year-old man was admitted for cholecystectomy. A complicated...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.03205
更新日期:2020-12-16 00:00:00
abstract:INTRODUCTION:The regular practice of physical activity (PA) has been associated with better health. In addition, job characteristics may determine the PA behaviours of employees, including the work shift. However, relatively few studies have examined the PA behaviour among shift workers. OBJECTIVE:This study aimed to ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.31.5.8628
更新日期:2015-05-01 00:00:00
abstract:INTRODUCTION:the relationship between changes in energy intake (EI) over the last few decades and the trends towards of excess weight in children is still debated. OBJECTIVE:to examine the relationship between energy and macronutrient intakes with adipostity in children, controlling for cardiorespiratory fitness (CRF)...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.32.4.9185
更新日期:2015-10-01 00:00:00
abstract::The modification of dietary patterns has led to a change in fatty acid consumption, with an increase in the consumption of ω-6 fatty acids and a marked reduction in the consumption of ω-3 fatty acids. This in turn has given rise to an imbalance in the ω-6/ω-3 ratio, which is now very different from the original 1:1 ra...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.1590/S0212-16112011000200013
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:tracheoesophageal fistula (TEF) may result from cancer or mechanical ventilation. Endoscopic Gastrostomy or Gastrojejunostomy (PEG/PEG-J) is used for nutritional support. OBJECTIVE:in TEF-patients, evaluating nutritional status when PEG is performed, safety of PEG/PEG-J and clinical outcome. METHODS:from t...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.32.2.9078
更新日期:2015-08-01 00:00:00
abstract:INTRODUCTION:Taekwondo (TKD) is a combat sport, which has also been proposed as a fitness program, with a strong anaerobic component. Creatine (Cr) supplementation is used to improve both anaerobic exercise performance and body composition. Therefore, Cr supplementation could be beneficial in TKD. AIMS:To determine th...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,随机对照试验
doi:10.3305/nh.2013.28.2.6314
更新日期:2013-03-01 00:00:00