Chronic ultraviolet B radiation-induced biochemical changes in the skin of hairless mice.


:Skh:HR-1 hairless mice were irradiated chronically with sub-erythemal doses of UVB radiation, and a number of biochemical parameters in the skin were determined after 6, 12, 18, and 24 wk of exposure. The parameters measured were water, collagen, elastin, and glycosaminoglycan content; collagenase and elastase levels; and Bz-Tyr-OEt (N-benzoyl-L-tyrosine ethyl ester) and BAPNA (alpha-N-benzoyl-DL-arginine-p-nitroanilide) hydrolyzing activities. Data for UVB radiation-exposed and chronological age-matched control mice were compared with respect to unit area and to unit mass of skin. On a unit area of skin basis, UVB radiation exposure increased the level of most parameters. The particular exceptions were collagen and collagenase which remained constant. On a mass of skin basis, though, there is an apparent decrease in collagen content because of the increase in the other skin components. This suggests that there is insufficient collagen in UVB radiation-exposed skin to support the increasing mass of the tissue.


Photochem Photobiol


Chatterjee R,Benzinger MJ,Ritter JL,Bissett DL




Has Abstract


1990-01-01 00:00:00












  • Pomegranate fruit extract modulates UV-B-mediated phosphorylation of mitogen-activated protein kinases and activation of nuclear factor kappa B in normal human epidermal keratinocytes paragraph sign.

    abstract::Excessive exposure of solar ultraviolet (UV) radiation, particularly its UV-B component, to humans causes many adverse effects that include erythema, hyperplasia, hyperpigmentation, immunosuppression, photoaging and skin cancer. In recent years, there is increasing use of botanical agents in skin care products. Pomegr...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Afaq F,Malik A,Syed D,Maes D,Matsui MS,Mukhtar H

    更新日期:2005-01-01 00:00:00

  • Identification and quantification of intrinsic optical contrast for near-infrared mammography.

    abstract::Near-infrared spectroscopy has been used to quantify the composition of healthy female breast tissue in vivo. By collecting transillumination spectra in the wavelength range 680-1100 nm at 7-9 positions on the breasts of five female volunteers, an attempt was made to quantify the intra- and intersubject variability of...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Quaresima V,Matcher SJ,Ferrari M

    更新日期:1998-01-01 00:00:00

  • A role for hydrogen peroxide in the pro-apoptotic effects of photodynamic therapy.

    abstract::Although the first reactive oxygen species (ROS) formed during irradiation of photosensitized cells is almost invariably singlet molecular oxygen (1O2), other ROS have been implicated in the phototoxic effects of photodynamic therapy (PDT). Among these are superoxide anion radical (*O2(-)), hydrogen peroxide (H2O2) an...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Price M,Terlecky SR,Kessel D

    更新日期:2009-11-01 00:00:00

  • Mechanisms for luminol-augmented chemiluminescence from neutrophils induced by leukotriene B4 and N-formyl-methionyl-leucyl-phenylalanine.

    abstract::Neutrophils stimulated with formyl-methionyl-leucyl-phenylalanine (fMLP) or leukotriene B4 (LTB4) generated kinetically distinctive luminol augmented chemiluminescence (LCL). Inhibitors of .O2- [superoxide-dismutase (SOD) or tiron], H2O2 (catalase), myeloperoxidase, MPO, (NaN3), HOCl (taurine) and .OH (mannitol) hampe...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Gyllenhammar H

    更新日期:1989-02-01 00:00:00

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    abstract::Intermolecular interactions of human serum proteins with a hydrophilic nonmetalloporphyrin, 13,17-bis(1-carboxypropionyl)carbomoylethyl-8-ethenyl-2-hydroxy-3-hydroxyiminoethylidene-2,7,12,18-tetramethylporphyrin sodium salt (ATX-S10 (Na)), or a hydrophilic gallium-metalloporphyrin, diethylenetriamine pentaacetic acid ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Yamaguchi M,Tanabe S,Nakajima S,Takemura T,Ogita K,Kuwayama H,Sakata I,Miyaki S,Suzuki K,Namiki H,Uzuka Y,Sarashina T

    更新日期:2004-09-01 00:00:00

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    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章,评审


    authors: Altun A,Yokoyama S,Morokuma K

    更新日期:2008-07-01 00:00:00

  • Effects of Combined Lysosomal and Mitochondrial Photodamage in a Non-small-Cell Lung Cancer Cell Line: The Role of Paraptosis.

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    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Kessel D,Reiners JJ Jr

    更新日期:2017-11-01 00:00:00

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    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Haylett AK,Ward TH,Moore JV

    更新日期:2003-10-01 00:00:00

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    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章,评审


    authors: van der Steen JB,Hellingwerf KJ

    更新日期:2015-09-01 00:00:00

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    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章,评审


    authors: Coohill TP

    更新日期:1991-11-01 00:00:00

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    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Yamamoto KT,Tokutomi S

    更新日期:1989-07-01 00:00:00

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    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Appenroth KJ,Gabrys H

    更新日期:2001-01-01 00:00:00

  • Photophysical properties of tin ethyl etiopurpurin I (SnET2) and tin octaethylbenzochlorin (SnOEBC) in solution and bound to albumin.

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    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Pogue BW,Redmond RW,Trivedi N,Hasan T

    更新日期:1998-12-01 00:00:00

  • Spectral shift of ultraweak photon emission from sweet potato during a defense response.

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    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Iyozumi H,Kato K,Makino T

    更新日期:2002-03-01 00:00:00

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    abstract::Evidence is mounting that UV-B and UV-A radiation affect skin differently in responses as diverse as erythema and elastosis. We found in this study that collagen metabolism was also differentially affected. Albino hairless mice were irradiated with two UV-A sources: (1) UVASUN 3000 (340-400 nm) for cumulative exposure...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Kligman LH,Gebre M

    更新日期:1991-08-01 00:00:00

  • Surface Functionalization of Green-synthesized Reduced Graphene Oxide with PPIX Enhances Photosensitization of Cancer Cells.

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    pub_type: 杂志文章


    authors: Shuvra Smita S,Das A,Barui A

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    abstract::An approximate formula for the UV Index (UVI) under cloud-free, unpolluted, low surface albedo conditions is: UVI approximately 12.5mu(o)(2.42)(Omega/300)(-1.23) where mu(o) is the cosine of the solar zenith angle and Omega is the total vertical ozone column (in Dobson Units, DU). The dependence on mu(o) and Omega is ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Madronich S

    更新日期:2007-11-01 00:00:00

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    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Stender IM,Bech-Thomsen N,Poulsen T,Wulf HC

    更新日期:1997-10-01 00:00:00

  • Is phototherapy safe for HIV-infected individuals?

    abstract::Patients infected with human immunodeficiency virus (HIV) have a high prevalence of UV radiation-responsive skin diseases including psoriasis, pruritus, eosinophilic folliculitis and eczemas. On the other hand, UV has been shown to suppress T cell-mediated immune responses and to induce activation and replication of H...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章,评审


    authors: Adams ML,Houpt KR,Cruz PD Jr

    更新日期:1996-08-01 00:00:00

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    abstract::The pharmacokinetics of Zn phthalocyanine (ZnPc) encapsulated in dipalmitoyl-phosphatidylcholine (DPPC) liposomes, injected intravenously in Skh:HR-1 nude mice, was monitored by two in vitro techniques and one in vivo technique, all based on fluorescence spectroscopy. The in vitro methods involve either fluorescence m...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Biolo R,Jori G,Kennedy JC,Nadeau P,Pottier R,Reddi E,Weagle G

    更新日期:1991-01-01 00:00:00

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    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Kessel D,Morgan A

    更新日期:1994-05-01 00:00:00

  • The plastoglobule: a bag full of lipid biochemistry tricks.

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    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章,评审


    authors: Bréhélin C,Kessler F

    更新日期:2008-11-01 00:00:00

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    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Enns L,Murray D,Mirzayans R

    更新日期:2000-10-01 00:00:00

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    abstract::The objective of this study was to assess the diagnostic potential of synchronous fluorescence (SF) spectroscopy (SFS) technique for the detection and characterization of normal and different malignancy stages of moderately differentiated squamous cell carcinoma (MDSCC), poorly differentiated squamous cell carcinoma (...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Ebenezar J,Aruna P,Ganesan S

    更新日期:2010-01-01 00:00:00

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    abstract::In this study, water-soaked seeds of sunflower were exposed to He-Ne laser irradiation of different energies to determine whether or not He-Ne laser irradiation caused changes to seed thermodynamic and germination parameters as well as effects on the activities of germination enzymes. The experiment comprised four ene...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Perveen R,Ali Q,Ashraf M,Al-Qurainy F,Jamil Y,Raza Ahmad M

    更新日期:2010-09-01 00:00:00

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    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Tandori J,Miksovska J,Valerio-Lepiniec M,Schiffer M,Maróti P,Hanson DK,Sebban P

    更新日期:2002-02-01 00:00:00

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    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章,评审


    authors: Dessinioti C,Antoniou C,Katsambas A,Stratigos AJ

    更新日期:2011-09-01 00:00:00

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    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Gokulnath S,Achary BS,Kumar CK,Trivedi R,Sridhar B,Giribabu L

    更新日期:2015-01-01 00:00:00

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    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Frederick JE,Slusser JR,Bigelow DS

    更新日期:2000-10-01 00:00:00

  • Characterization of photocycle intermediates in crystalline photoactive yellow protein.

    abstract::The photocycle in photoactive yellow protein (PYP) crystals was studied by single-crystal absorption spectroscopy with experimental setups for low-temperature and time-resolved measurements. Thin and flat PYP crystals, suitable for light absorption studies, were obtained using special crystallization conditions. Illum...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章


    authors: Kort R,Ravelli RB,Schotte F,Bourgeois D,Crielaard W,Hellingwerf KJ,Wulff M

    更新日期:2003-08-01 00:00:00