Taking HSCs down a Notch in leukemia.

Abstract:

:The Notch signaling pathway is activated in the majority of T cell acute lymphoblastic leukemias (T-ALL). Adding to the complexity of Notch signaling in hematopoiesis, recently in Nature, Klinakis et al. (2011) demonstrate a tumor-suppressor function for the Notch pathway in myeloid malignancy.

journal_name

Cell Stem Cell

journal_title

Cell stem cell

authors

Walkley CR,Izon DJ,Purton LE

doi

10.1016/j.stem.2011.04.010

subject

Has Abstract

pub_date

2011-06-03 00:00:00

pages

602-3

issue

6

eissn

1934-5909

issn

1875-9777

pii

S1934-5909(11)00175-5

journal_volume

8

pub_type

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