Partial covalent labeling with pyridoxal 5'-phosphate induces bis(sulfosuccinimidyl)suberate crosslinking of band 3 protein tetramers in intact human red blood cells.

abstract：:SIRT5 is one of the seven mammalian sirtuins which are NAD+-dependent deacylases. In human beings, SIRT5 gene encodes for four SIRT5 protein isoforms, namely SIRT5iso1, SIRT5iso2, SIRT5iso3, and SIRT5iso4. Previous studies have focused mostly on SIRT5iso1. Characteristics regarding localization, activity and tissue di...

journal_title：Biochemical and biophysical research communications

authors： Du Y,Hu H,Hua C,Du K,Wei T

更新日期：2018-09-05 00:00:00

abstract：:The presence of calcium-dependent proteinase in plants was investigated using soluble proteins from Arabidopsis root cultures. Calcium increased the proteolytic activity by two to three fold. Calcium-stimulated proteolytic activity was inhibited by different protease inhibitors. The highest inhibition (79%) of calcium...

journal_title：Biochemical and biophysical research communications

authors： Reddy AS,Safadi F,Beyette JR,Mykles DL

更新日期：1994-03-30 00:00:00

abstract：:Polarization of epithelial cells requires vectorial sorting and transport of polarity proteins to apical or basolateral domains. Kif5b is the mouse homologue of the human ubiquitous Kinesin Heavy Chain (uKHC). To investigate the function of Kif5b in epithelial cells, we examined the phenotypes of Kif5b-deficient MDCK ...

journal_title：Biochemical and biophysical research communications

authors： Cui J,Jin G,Yu B,Wang Z,Lin R,Huang JD

更新日期：2015-07-17 00:00:00

abstract：:We previously showed that beta-defensin-1 (BD-1), an anti-microbial peptide, is up-regulated during progressive hyperglycemia in the kidneys of the GK rat [R.A. Page, C.A. Morris, J.D. Williams, C.J. von Ruhland, A.N. Malik, Isolation of diabetes-associated kidney genes using differential display, Biochem. Biophys. Re...

journal_title：Biochemical and biophysical research communications

authors： Malik AN,Al-Kafaji G

更新日期：2007-02-09 00:00:00

abstract：:Brewers yeast contains factors that increase and decrease glucose tolerance. Hop components (lupulones) that adhere to yeast during the brewing process elicit a variety of biological effects including the induction of hepatic cytochrome P4503A. Colupulone was tested for its effects on glucose tolerance and cytochrome ...

journal_title：Biochemical and biophysical research communications

authors： Mannering GJ,Shoeman JA,Shoeman DW

更新日期：1994-05-16 00:00:00

abstract：:In this paper we describe for the first time the inhibitory effect of three amphiphilic cations, trifluoperazine, propranolol and dibucaine on mitochondrial protein import. The amphiphilic cations did not affect binding of mitochondrial precursor proteins to mitochondria. Import into mitoplasts was affected in a simil...

journal_title：Biochemical and biophysical research communications

authors： Pavlov PF,Glaser E

更新日期：1998-11-09 00:00:00

abstract：:Genomic DNA of the phytopathogenic Erwinia chrysanthemi PY35 was partially digested with Sau3AI, ligated into the BamHI site of pBluescript II SK+, and introduced into E. coli. One clone that was able to hydrolyse carboxymethylcellulose and polygalacturonic acid was selected. A 2.9 kb fragment containing the pelL1 gen...

journal_title：Biochemical and biophysical research communications

authors： Park SR,Kim MK,Kim JO,Bae DW,Cho SJ,Cho YU,Yun HD

更新日期：2000-02-16 00:00:00

abstract：:Histone deacetylases (HDACs) hyper-activity in hepatocellular carcinoma (HCC) is often associated with patients' poor prognosis. Our previous study has shown that resminostat, a novel HDAC inhibitor (HDACi), activated mitochondrial permeability transition pore (mPTP)-dependent apoptosis pathway in HCC cells. Here we e...

journal_title：Biochemical and biophysical research communications

authors： Peng X,Zhang D,Li Z,Fu M,Liu H

更新日期：2016-09-02 00:00:00

abstract：:Dexamethasone (DEX), a glucocorticoid which induces cleft palate, causes marked alterations in the synthesis and degradation of phosphatidylinositol (PI) but not phosphatidylcholine in an established fibroblastic cell line derived from a human embryonic palate. Incorporation of radiolabeled inositol into phosphatidyli...

journal_title：Biochemical and biophysical research communications

authors： Grove RI,Willis WD,Pratt RM

更新日期：1983-01-14 00:00:00

abstract：:Jasmonates are plant lipid-derived oxylipins that act as key signaling compounds in plant immunity, germination, and development. Although some physiological activities of natural jasmonates in mammalian cells have been investigated, their anti-inflammatory actions in mammalian cells remain unclear. Here, we investiga...

journal_title：Biochemical and biophysical research communications

authors： Taki-Nakano N,Kotera J,Ohta H

更新日期：2016-05-13 00:00:00

abstract：:To explore the estrogen-regulated genes genome-widely in breast cancer, cap analysis of gene expression (CAGE) sequencing was performed in MCF-7 cells under estrogen treatment. Estrogen-regulated expressional changes were found in 1537 CAGE tag clusters (TCs) (⩾1.5 or ⩽0.66-folds). Among them, 15 TCs were situated in ...

journal_title：Biochemical and biophysical research communications

authors： Yamaga R,Ikeda K,Boele J,Horie-Inoue K,Takayama K,Urano T,Kaida K,Carninci P,Kawai J,Hayashizaki Y,Ouchi Y,de Hoon M,Inoue S

更新日期：2014-05-09 00:00:00

abstract：:Exposure of pancreatic islet B-cells to D-glucose and many other insulinotropic agents results in an increase of cytoplasmic calcium concentration, which triggers the exocytosis of secretroy granules. Previous studies have demonstrated that calcium itself, at concentrations ranging from 2 to 18 mM, is able to induce a...

journal_title：Biochemical and biophysical research communications

authors： Rasschaert J,Malaisse WJ

更新日期：1999-11-02 00:00:00

abstract：:The disruption of intestinal mucosal immune tolerance can lead to the development of intestinal immune diseases such as food allergy (FA). Regulatory T cells (Tregs) in the mucosa play a critical role in maintaining peripheral immune tolerance in the intestine, and retinoic acid (RA) is absolutely required for the ind...

journal_title：Biochemical and biophysical research communications

authors： Yamamoto T,Matsunami E,Komori K,Hayashi S,Kadowaki M

更新日期：2019-08-27 00:00:00

abstract：:Prion diseases are characterized by the accumulation of a pathological form of prion protein (PrP(Sc)), which behaves as an infectious agent. Here we developed an in vitro co-culture system to analyze the PrP(Sc) transmission from ScN2a cell, which persistently retains PrP(Sc), to naïve N2a cell. In this cell-to-cell ...

journal_title：Biochemical and biophysical research communications

authors： Tanaka M,Hara H,Nishina H,Hanada K,Hagiwara K,Maehama T

更新日期：2010-07-02 00:00:00

abstract：:Saccharomyces cerevisiae RecQ helicase (Sgs1) combines with DNA topoisomerase III (Top3) and RecQ-mediated genome instability 1 (Rmi1) to form an evolutionarily conserved complex that is required for processing homologous recombination intermediates and restarting collapsed replication forks. It was previously reporte...

journal_title：Biochemical and biophysical research communications

authors： Lai MS,Seki M,Tada S,Enomoto T

更新日期：2012-10-26 00:00:00

abstract：:While Aspergillus ficuum phytaseA (phyA) was rapidly inactivated by 1,2-cyclohexanedione and phenylglyoxal, both specific modifiers of arginine, phytaseB (phyB) showed a markedly different behavior. First, phyB was totally insensitive to 1,2-cyclohexanedione even in the presence of 0.2 M guanidinium hydrochloride; sec...

journal_title：Biochemical and biophysical research communications

authors： Ullah AH,Sethumadhavan K

更新日期：1998-02-13 00:00:00

abstract：:p53 mutations are mostly single amino acid changes resulting in expression of a stable mutant protein with "gain of function" (GOF) activity having a dominant oncogenic role rather than simple loss of function of wild-type p53. Knock-down of mutant p53 in human lung cancer cell lines with different endogenous p53 muta...

journal_title：Biochemical and biophysical research communications

authors： Vaughan CA,Frum R,Pearsall I,Singh S,Windle B,Yeudall A,Deb SP,Deb S

更新日期：2012-11-09 00:00:00

abstract：:Labial grooves in maxillary incisors have been reported in several wild-type rodent species. Previous studies have reported age-dependent labial grooves occur in moderate prevalence in C57BL/6 mice; however, very little is known about the occurrence of such grooves. In the present study, we observed age-dependent groo...

journal_title：Biochemical and biophysical research communications

authors： Ota MS,Kondo K,Li Y,Iseki S,Yamashita A,Gibson CW,Kondo T

更新日期：2018-02-05 00:00:00

abstract：:Bone is a rigid yet dynamic organ, and this dynamism is mediated by the delicate balance between osteoclastic bone resorption and osteoblastic bone formation. However, excessive activation of osteoclasts is responsible for many bone diseases such as osteoporosis, Paget disease, and tumor bone metastasis. Agents that c...

journal_title：Biochemical and biophysical research communications

authors： Zhou F,Shen Y,Liu B,Chen X,Wan L,Peng D

更新日期：2017-03-18 00:00:00

abstract：:Parkinson's disease (PD) is one of the most prevalent neurodegenerative diseases but its etiology is unclear. Alpha-synuclein (alpha-SN) is a major component of Lewy bodies and Lewy neurites, and its missense mutations, A30P and A53T, cause familial PD. In PD, alpha-SN-positive glial inclusions are distributed mainly ...

journal_title：Biochemical and biophysical research communications

authors： Kohno R,Sawada H,Kawamoto Y,Uemura K,Shibasaki H,Shimohama S

更新日期：2004-05-21 00:00:00

abstract：:Vinculin and meta-vinculin are related proteins that localize to adherens junctions. To facilitate studies on the biology of these proteins cDNA clones were isolated from a chick embryonic library made in lambda gt 11. Three clones, accounting for 1/2 of the vinculin message, were identified by immunological analyses ...

journal_title：Biochemical and biophysical research communications

authors： Coutu MD,Simon DJ,Brown AE,Craig SW

更新日期：1987-09-15 00:00:00

abstract：:The cell-specific cytosolic delivery of functional macromolecules with high efficiency is of great significance in molecular medicine and biotechnology. Herein, we present a Shiga-like toxin II-based high-efficiency and receptor-specific intracellular delivery system. We designed and constructed the Shiga-like toxin-b...

journal_title：Biochemical and biophysical research communications

authors： Ryou JH,Sohn YK,Hwang DE,Kim HS

更新日期：2015-09-04 00:00:00

abstract：:Hepatic glucokinase is induced by insulin and repressed by glucagon. The effects of epidermal growth factor (EGF) on glucokinase expression were investigated in rat hepatocytes. EGF does not affect the decline in glucokinase activity in hepatocytes cultured for 48h in the absence of insulin, but it counteracts the inc...

journal_title：Biochemical and biophysical research communications

authors： Beresford GW,Agius L

更新日期：1994-06-15 00:00:00

abstract：:The role of hepatic nuclear factor 1α (HNF-1α) and its response element in the expression of glutathione S-transferase A1 (GSTA1) was investigated in hepatocytes cells injury induced by acetaminophen (APAP). Treatment of hepatocytes with C2-ceramide exacerbated cells injury with GSTA1 mRNA level reducing. Contrastingl...

journal_title：Biochemical and biophysical research communications

authors： Li Y,Hao B,Muhammad I,Zhang Y,Yang Y,Shi C,Chang Y,Li R,Li C,Liu F

更新日期：2019-08-13 00:00:00

abstract：:Nitrosporeusine A (NA) has been recently reported to exert anti-inflammatory and renal protective effects, but whether NA can attenuate sepsis-associated acute kidney injury (AKI) has not yet been reported. In this study, our results found that cecal ligation and puncture (CLP) reduced renal PGC-1α expression and indu...

journal_title：Biochemical and biophysical research communications

authors： Zhao Y,Nie M,Xu P,Li H,Xu L,Cheng XQ,Lei YQ

更新日期：2019-07-30 00:00:00

abstract：:The acidic leucine-rich nuclear phosphoprotein 32B (ANP32B) is a member of a conserved superfamily of nuclear proteins whose functions are largely unknown. In our previous work, ANP32B was identified as a novel direct substrate for caspase-3 and acted as a negative regulator for leukemic cell apoptosis. In this work, ...

journal_title：Biochemical and biophysical research communications

authors： Yu Y,Shen SM,Zhang FF,Wu ZX,Han B,Wang LS

更新日期：2012-07-13 00:00:00

abstract：:Cell to cell interaction in bone marrow is crucial for differentiation of hematopoietic cells. We have shown that EphB4 receptor is expressed in erythroid progenitor and its activation accelerates erythroid differentiation. To elucidate the role of EphB4 activation in erythropoiesis, we analyzed effects of EphB4 on ce...

journal_title：Biochemical and biophysical research communications

authors： Sakamoto H,Zhang XQ,Suenobu S,Ohbo K,Ogawa M,Suda T

更新日期：2004-08-27 00:00:00

abstract：:Interleukin-2 (IL-2) is a cytokine essential for the growth and proliferation of T-cells. The purpose of this research was to study the effects of altering the "kink" caused by Pro in an alpha-helix of the protein. The Pro-47 residue was chosen because it was originally, but mistakenly, traced to the kink of an alpha-...

journal_title：Biochemical and biophysical research communications

authors： Lee BL,Ciardelli TL

更新日期：1997-04-17 00:00:00

abstract：:Peptides with a molecular weight of 5 kDa have been isolated from seeds of the pinto bean and red bean, respectively. The peptides manifest an N-terminal sequence with remarkable resemblance to those of cowpea 10-kDa protein precursor and garden pea disease resistance response protein. The bean peptides possess potent...

journal_title：Biochemical and biophysical research communications

authors： Ye XY,Ng TB

更新日期：2001-07-13 00:00:00

abstract：:Each chromosome occupies its own-specific space called a 'territory' within the interphase nucleus, and the arrangement of chromosome territories (CTs) is important in epigenetic mechanisms. The molecular mechanism to determine the positioning of CTs, however, remains unknown. On the other hand, dioxin is known to be ...

journal_title：Biochemical and biophysical research communications

authors： Oikawa K,Yoshida K,Takanashi M,Tanabe H,Kiyuna T,Ogura M,Saito A,Umezawa A,Kuroda M

更新日期：2008-09-19 00:00:00