Abstract：
:We report 2 cases of a lesion that we term inverted papilloma of the lower female genital tract, occurring in the cervix and upper vagina of 60- and 50-year-old women, respectively. Microscopically, the features were similar to those of inverted transitional papilloma of the urinary bladder with interconnecting islands, trabeculae, and solid sheets of bland transitional epithelium with an inverted growth pattern. There were small foci of squamous and glandular differentiation in the cervical case. Linear array human papillomavirus genotyping revealed human papillomavirus type 42 in both cases. Inverted papilloma in the lower female genital tract is extremely rare with, as far as we are aware, only 3 previously reported similar cases in the cervix and none in the vagina. Our results suggest that these neoplasms when occurring in the lower female genital tract may be associated with low-risk human papillomavirus, perhaps specifically human papillomavirus 42.
journal_name
Hum Patholjournal_title
Human pathologyauthors
Hennell C,Jamison J,Wells M,McCluggage WGdoi
10.1016/j.humpath.2011.03.011subject
Has Abstractpub_date
2012-03-01 00:00:00pages
435-9issue
3eissn
0046-8177issn
1532-8392pii
S0046-8177(11)00201-2journal_volume
43pub_type
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