当前位置： SCI文献检索 > JOURNAL OF NEUROIMMUNOLOGY期刊下所有文献 > A challenging diagnosis of reversible "vascular" dementia: Cerebral amyloid angiopathy-related inflammation.

A challenging diagnosis of reversible "vascular" dementia: Cerebral amyloid angiopathy-related inflammation.

Abstract：

:Cerebral amyloid angiopathy-related inflammation (CAA-ri) is a rare and treatable variant of CAA likely due to an autoimmune response directed toward beta-amyloid deposits. Cognitive and behavioral manifestations are the most common symptoms, followed by focal neurological signs, headache and seizures, associated with characteristics neuroradiological features on brain magnetic resonance imaging (MRI). We describe the clinical course, radiological features and therapeutic approach of two patients with probable CAA-ri with the aim of emphasizing the importance of an early diagnosis of this potentially reversible disease in different neurological settings, such as memory clinics and stroke units.

journal_name

J Neuroimmunol

journal_title

Journal of neuroimmunology

authors

Poli L,De Giuli V,Piazza F,Volonghi I,Bigliardi G,Vallone S,Nichelli PF,Gasparotti R,Zini A,Padovani A,Pezzini A

doi

10.1016/j.jneuroim.2019.577109

subject

Has Abstract

pub_date

2020-01-15 00:00:00

pages

577109

eissn

0165-5728

issn

1872-8421

pii

S0165-5728(19)30517-X

journal_volume

338

pub_type

杂志文章

相关文献

JOURNAL OF NEUROIMMUNOLOGY文献大全
  • One calcitriol dose transiently increases Helios+ FoxP3+ T cells and ameliorates autoimmune demyelinating disease.

    abstract：:Multiple sclerosis (MS) is an incurable inflammatory demyelinating disease. We investigated one calcitriol dose plus vitamin D3 (calcitriol/+D) as a demyelinating disease treatment in experimental autoimmune encephalomyelitis (EAE). Evidence that calcitriol-vitamin D receptor pathway deficits may promote MS, and data ...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2013.07.016

    authors： Nashold FE,Nelson CD,Brown LM,Hayes CE

    更新日期：2013-10-15 00:00:00

  • Human immunodeficiency virus type-1 Nef protein induces blood-brain barrier disruption in the rat: role of matrix metalloproteinase-9.

    abstract：:We recently showed that MMP-9 activity was detectable in the cerebrospinal fluid (CSF) of about half of neurologically symptomatic HIV-infected patients. Using an experimental animal model, we detected MMP-9 activity in CSF samples from rats that had been injected intracisternally with recombinant HIV-1 Nef protein, b...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/s0165-5728(99)00170-8

    authors： Sporer B,Koedel U,Paul R,Kohleisen B,Erfle V,Fontana A,Pfister HW

    更新日期：2000-01-24 00:00:00

  • TNF and sTNFR1/2 plasma levels in ALS patients.

    abstract：:The involvement of the immune system has been hypothesized in the pathogenesis of amyotrophic lateral sclerosis (ALS). In this study a significantly higher level of TNF-alpha and its soluble receptors, TNF-R1 and TNF-R2, has been found in plasma of patients affected by the sporadic form of ALS compared to normal subje...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2007.10.028

    authors： Cereda C,Baiocchi C,Bongioanni P,Cova E,Guareschi S,Metelli MR,Rossi B,Sbalsi I,Cuccia MC,Ceroni M

    更新日期：2008-02-01 00:00:00

  • Treatment with atacicept enhances neuronal cell death in a rat model of optic neuritis.

    abstract：:We investigated the effect of atacicept, a recombinant fusion protein blocking BLyS and APRIL and acting on B cells, on degeneration of retinal ganglion cells (RGCs) during experimental autoimmune encephalomyelitis (EAE). We used myelin oligodendrocyte glycoprotein in Brown Norway rats to induce a variant of EAE which...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2014.01.005

    authors： Kretzschmar B,Hein K,Moinfar Z,Könnecke B,Sättler MB,Hess H,Weissert R,Bähr M

    更新日期：2014-03-15 00:00:00

  • Interferon-beta specifically inhibits interferon-gamma-induced class II major histocompatibility complex gene transcription in a human astrocytoma cell line.

    abstract：:We established cultures of human astrocytes and astrocytoma cells from surgical specimens, to study regulation of class II major histocompatibility (MHC) complex antigen expression by interferons. Using these cultures we previously showed that expression of the class II MHC determinant HLA-DR could be induced by inter...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/0165-5728(91)90054-b

    authors： Ransohoff RM,Devajyothi C,Estes ML,Babcock G,Rudick RA,Frohman EM,Barna BP

    更新日期：1991-08-01 00:00:00

  • Inhibition of acetylcholine receptor function by seronegative myasthenia gravis non-IgG factor correlates with desensitisation.

    abstract：:15% of myasthenia gravis (MG) patients do not have antibodies against the acetylcholine receptor (AChR). Some of these "seronegative" MG patients have antibodies against muscle specific kinase (MuSK), and many have a non-IgG factor that acutely inhibits AChR function in a muscle-like cell line, CN21. Here we show, usi...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2005.01.009

    authors： Spreadbury I,Kishore U,Beeson D,Vincent A

    更新日期：2005-05-01 00:00:00

  • Antigen presenting cells treated in vitro by macrophage colony-stimulating factor and autoantigen protect mice from autoimmunity.

    abstract：:Macrophage colony-stimulating factor (M-CSF) is a critical cytokine in the development of monocytic lineage and may have immunoregulatory properties. Here we show that peritoneal antigen presenting cells (APCs) treated with M-CSF produced decreased levels of proinflammatory cytokines IFN-gamma, TNF-alpha and IL-12. Th...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2007.09.021

    authors： Guan Y,Yu S,Zhao Z,Ciric B,Zhang GX,Rostami A

    更新日期：2007-12-01 00:00:00

  • (5R)-5-hydroxytriptolide (LLDT-8), a novel triptolide derivative, prevents experimental autoimmune encephalomyelitis via inhibiting T cell activation.

    abstract：:A novel triptolide derivative (5R)-5-hydroxytriptolide (LLDT-8) has been shown to have potent immunosuppressive activities. Here LLDT-8 was evaluated in experimental autoimmune encephalomyelitis (EAE), the model of multiple sclerosis (MS). LLDT-8 reduced the incidence and severity of EAE, which was associated with the...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2006.03.011

    authors： Fu YF,Zhu YN,Ni J,Zhong XG,Tang W,Zhou R,Zhou Y,Dong JR,He PL,Wan H,Li YC,Yang YF,Zuo JP

    更新日期：2006-06-01 00:00:00

  • Expression and function of inducible nitric oxide synthase in neurons.

    abstract：:Enzymatically derived nitric oxide (NO) has been implicated in numerous physiological and pathological processes in the brain. Whereas during development NO participates in developmental and maturation processes, excess NO production in the adult in response to inflammation, injury, or trauma participates in both cell...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章,评审

    doi：10.1016/s0165-5728(01)00246-6

    authors： Heneka MT,Feinstein DL

    更新日期：2001-03-01 00:00:00

  • Immunogenetic markers in chlorpromazine-induced tardive dyskinesia.

    abstract：:The presence and severity of tardive dyskinesia were determined in 66 patients with chronic psychiatric disorders treated with chlorpromazine. The patients were classified according to the presence of antinuclear antibodies, the lupus anticoagulant, and the HLA antigen Bw44. The severity of orofacial dyskinesia was es...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/s0165-5728(86)80008-x

    authors： Canoso RT,Romero JA,Yunis EJ

    更新日期：1986-09-01 00:00:00

  • Invariant NKT cells in adrenoleukodystrophy patients and mice.

    abstract：:X-linked adrenoleukodystrophy (X-ALD) is a severe neurological disease characterized by progressive demyelination within the CNS, adrenal insufficiency, and is associated with an accumulation of saturated very long chain fatty acids in plasma and tissues of patients. iNKT cells, a distinct lineage of T cells recognizi...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2010.09.003

    authors： Gautron AS,Giquel B,Beaudoin L,Autrusseau E,Speak A,Platt F,Kemp S,Pujol A,Aubourg P,Lehuen A

    更新日期：2010-12-15 00:00:00

  • The role of exosomes in CNS inflammation and their involvement in multiple sclerosis.

    abstract：:Multiple sclerosis (MS) is a putative autoimmune disease of the central nervous system (CNS) in which autoreactive immune cells recognizing myelin antigens lead to demyelination and axonal injury. Mechanisms relevant to the pathogenesis of MS have not been fully elucidated, particularly those underlying initiation of ...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jneuroim.2017.02.002

    authors： Selmaj I,Mycko MP,Raine CS,Selmaj KW

    更新日期：2017-05-15 00:00:00

  • Continuous in vivo treatment with catecholamines suppresses in vitro reactivity of rat peripheral blood T-lymphocytes via alpha-mediated mechanisms.

    abstract：:A 20 h continuous treatment of rats with catecholamines, using subcutaneously implantable retard tablets, had either no (adrenaline, isoproterenol, midodrine) or a slight (noradrenaline) suppressive effect on the in vitro responsiveness of peripheral blood T-lymphocytes. A marked suppression of the mitogen response en...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/0165-5728(92)90154-d

    authors： Felsner P,Hofer D,Rinner I,Mangge H,Gruber M,Korsatko W,Schauenstein K

    更新日期：1992-03-01 00:00:00

  • Initial characterization and autoradiographic localization of a novel sigma/opioid binding site in immune tissues.

    abstract：:High concentrations of novel, haloperidol- and DTG-inaccessible (+)-[3H]-3-PPP binding sites were found in human peripheral blood leukocytes rat spleen and splenocytes, but not in rat brain. Splenic sites were localized in a course punctate pattern in the marginal zones and red pulp. The pharmacology of the splenic si...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/0165-5728(96)00041-0

    authors： Whitlock BB,Liu Y,Chang S,Saini P,Ha BK,Barrett TW,Wolfe SA Jr

    更新日期：1996-07-01 00:00:00

  • Microglia are activated to become competent antigen presenting and effector cells in the inflammatory environment of the Theiler's virus model of multiple sclerosis.

    abstract：:Theiler's murine encephalomyelitis virus-induced demyelinating disease (TMEV-IDD) is a well-characterized murine model of the chronic-progressive form of human multiple sclerosis (MS) characterized by the activation of myelin-specific autoreactive CD4 Th1 cells via epitope spreading. To gain an understanding of the po...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2003.08.032

    authors： Mack CL,Vanderlugt-Castaneda CL,Neville KL,Miller SD

    更新日期：2003-11-01 00:00:00

  • Chronic restraint stress promotes immune suppression through toll-like receptor 4-mediated phosphoinositide 3-kinase signaling.

    abstract：:Stress, either psychological or physical, can have a dramatic impact on the immune system. Toll-like receptors (TLRs) play a pivotal role in the induction of innate and adaptive immune response. We have reported that stress modulates the immune response in a TLR4-dependent manner. However, the mechanisms underlying TL...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2008.08.011

    authors： Zhang Y,Zhang Y,Miao J,Hanley G,Stuart C,Sun X,Chen T,Yin D

    更新日期：2008-11-15 00:00:00

  • Visualisation of the kinetics of macrophage infiltration during experimental autoimmune encephalomyelitis by magnetic resonance imaging.

    abstract：:Macrophages are considered to be the predominant effector cells in multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE). Ultra small particles of iron oxide (USPIO) can be used to detect macrophage infiltrates in the CNS with magnetic resonance imaging (MRI). Here, we investigat...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2007.11.008

    authors： Baeten K,Hendriks JJ,Hellings N,Theunissen E,Vanderlocht J,Ryck LD,Gelan J,Stinissen P,Adriaensens P

    更新日期：2008-03-01 00:00:00

  • Enhancement of EAE and induction of autoantibodies to T-cell epitopes in mice infected with a recombinant vaccinia virus encoding myelin proteolipid protein.

    abstract：:SJL/J mice were infected with a recombinant vaccinia virus encoding myelin proteolipid protein (PLP) (VVplp). Antibody responses to whole PLP and to encephalitogenic peptides, p139-151, p178-191 or p104-117 were measured after vaccination and following challenge with these three PLP peptides. Competitive ELISAs showed...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/s0165-5728(96)00235-4

    authors： Wang LY,Fujinami RS

    更新日期：1997-05-01 00:00:00

  • Methylene blue alleviates experimental autoimmune encephalomyelitis by modulating AMPK/SIRT1 signaling pathway and Th17/Treg immune response.

    abstract：:Methylene blue (MB) is an effective neuroprotectant in many neurological disorders. AMP-activated protein kinase (AMPK)/silent mating-type information regulation 2 homolog 1 (SIRT1) plays a crucial role in maintaining inflammatory responses and shows a synergistic effect on cell homeostasis. We investigated the effect...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2016.08.014

    authors： Wang J,Zhao C,Kong P,Bian G,Sun Z,Sun Y,Guo L,Li B

    更新日期：2016-10-15 00:00:00

  • Effects on axonal conduction of anti-ganglioside sera and sera from patients with Guillain-Barré syndrome.

    abstract：:The efficacy of plasma exchange as a therapy for Guillain-Barré syndrome (GBS) suggests that humoral factors might contribute to the axonal conduction block responsible for the major symptoms of the disease. To explore this possibility, we have applied sera to rat spinal roots in vitro while monitoring axonal conducti...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/s0165-5728(03)00156-5

    authors： Dilley A,Gregson NA,Hadden RD,Smith KJ

    更新日期：2003-06-01 00:00:00

  • Endogenous spinal cord stem cells in multiple sclerosis and its animal model.

    abstract：:The adult mammalian spinal cord (SC) harbors neural stem cells (NSCs). The SC-NSCs are mostly quiescent during physiological conditions but are quickly activated in traumatic injury models. The SC-NSCs generate mostly glia, but are able to differentiate into neurons when affected by favourable conditions. An example i...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jneuroim.2016.11.006

    authors： Covacu R,Brundin L

    更新日期：2019-06-15 00:00:00

  • The significance of abnormal immune responses in patients with multiple sclerosis.

    abstract：:Early diagnosis of multiple sclerosis (MS) may be assisted by tests for the abnormal immune responses of the central nervous system (CNS) including oligoclonal IgG bands in the cerebrospinal fluid (CSF), increased CNS IgG synthesis, increased CNS antibody synthesis against multiple viruses and increased numbers of enl...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章,评审

    doi：10.1016/0165-5728(81)90040-0

    authors： Iivanainen MV

    更新日期：1981-06-01 00:00:00

  • Microglial cell activation in demyelinating canine distemper lesions.

    abstract：:Microglia cells are the principal immune effector elements of the brain responding to any pathological event. To elucidate the possible role of microglia in initial non-inflammatory demyelination in canine distemper virus (CDV) infection, microglia from experimentally CDV infected dogs were isolated ex vivo by density...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2004.05.001

    authors： Stein VM,Czub M,Schreiner N,Moore PF,Vandevelde M,Zurbriggen A,Tipold A

    更新日期：2004-08-01 00:00:00

  • Mast cell transcripts are increased within and outside multiple sclerosis lesions.

    abstract：:Few histological studies have reported an increased of mast cells (MCs) in the brain of MS patients; we have therefore investigated whether this accumulation is associated with disease activity. We assessed a large series of post-mortem white matter samples from MS patients (n=59, 20 patients) and controls (n=28, 28 s...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2008.01.017

    authors： Couturier N,Zappulla JP,Lauwers-Cances V,Uro-Coste E,Delisle MB,Clanet M,Montagne L,Van der Valk P,Bö L,Liblau RS

    更新日期：2008-03-01 00:00:00

  • Fatty acid binding protein 4 is associated with stroke risk and severity in patients with acute ischemic stroke.

    abstract：OBJECTIVE:The role of fatty acid-binding proteins (FABPs) in atherosclerosis has been investigated. The aim of this study was to verify the hypothesis that higher levels of serum FABP4 could be a biomarker for stroke and associated with stroke severity in Chinese patients with ischemic stroke. METHODS:All consecutive ...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2017.07.011

    authors： Chang L,Zhang J,Liu L,Huang Z,Han Y,Zhu Y

    更新日期：2017-10-15 00:00:00

  • Cytokines in cerebrospinal fluid of neurosyphilis patients: Identification of Urokinase plasminogen activator using antibody microarrays.

    abstract：:Little is known regarding protein responses to syphilis infection in cerebrospinal fluid (CSF) of patients presenting with neurosyphilis. Protein and antibody arrays offer a new opportunity to gain insights into global protein expression profiles in these patients. Here we obtained CSF samples from 46 syphilis patient...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2015.12.010

    authors： Lu P,Zheng DC,Fang C,Huang JM,Ke WJ,Wang LY,Zeng WY,Zheng HP,Yang B

    更新日期：2016-04-15 00:00:00

  • The accuracy of flow cytometric cell-based assay to detect anti-myelin oligodendrocyte glycoprotein (MOG) antibodies determining the optimal method for positivity judgement.

    abstract：:To illustrate the accuracy of the fluorescence-activated cell sorting cell-based assay (FACS-CBA) and to detect anti-myelin oligodendrocyte glycoprotein (MOG) antibodies and ascertain the optimal method for positivity judgement, referencing the findings of microscopic CBA. We tested serum anti-MOG antibodies in 57 pat...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2019.577021

    authors： Sugimoto K,Mori M,Liu J,Tanaka S,Kaneko K,Oji S,Takahashi T,Uzawa A,Uchida T,Masuda H,Ohtani R,Nomura K,Hiwasa T,Kuwabara S

    更新日期：2019-11-15 00:00:00

  • Local neutrophil influx following lateral fluid-percussion brain injury in rats is associated with accumulation of complement activation fragments of the third component (C3) of the complement system.

    abstract：:Traumatic brain injury can lead to locally destructive secondary events mediated by several inflammatory components. Following lateral fluid-percussion (FP) brain injury in rats, we examined cortical and hippocampal sections for neutrophil infiltration and accumulation of complement component C3. Neutrophil influx int...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/s0165-5728(00)00183-1

    authors： Keeling KL,Hicks RR,Mahesh J,Billings BB,Kotwal GJ

    更新日期：2000-06-01 00:00:00

  • Altered expression and secretion of colonic interleukin-6 in a stress-sensitive animal model of brain-gut axis dysfunction.

    abstract：:Interleukin-6 (IL-6) can activate gastrointestinal submucosal neurons, with associated implications for motility and secretory function. Patients with irritable bowel syndrome (IBS) have elevated levels of circulating IL-6. Colons from the Wistar Kyoto (WKY) rat model of IBS secrete more IL-6 (12.84 pg/ml) than contro...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2011.04.003

    authors： O'Malley D,Dinan TG,Cryan JF

    更新日期：2011-06-01 00:00:00

  • Lymphocyte subsets and CD45RA positive T-cells in normal canine cerebrospinal fluid.

    abstract：:In order to evaluate changes in lymphocyte subpopulations of cerebrospinal fluid (CSF) cells in neurological diseases, normal control data have to be established. In this study we evaluated CSF samples from 65 dogs of both sexes and various breeds with an age range between 5 months and 6 years, and 20 one-year-old hea...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/S0165-5728(97)00192-6

    authors： Tipold A,Moore P,Jungi TW,Sager H,Vandevelde M

    更新日期：1998-02-01 00:00:00