Abstract:
:The presence and severity of tardive dyskinesia were determined in 66 patients with chronic psychiatric disorders treated with chlorpromazine. The patients were classified according to the presence of antinuclear antibodies, the lupus anticoagulant, and the HLA antigen Bw44. The severity of orofacial dyskinesia was estimated using the Rockland Research Institute Scale. Patients with autoantibodies and the Bw44 antigen had higher tardive dyskinesia scores than those with AAB without the Bw44 antigen and also patients without autoantibodies regardless of their HLA phenotype (P less than 0.01). These studies suggest that the presence of autoantibodies in association with the HLA Bw44 antigen is related to, and can be a predictor of, neurological complications of long-term chlorpromazine therapy.
journal_name
J Neuroimmunoljournal_title
Journal of neuroimmunologyauthors
Canoso RT,Romero JA,Yunis EJdoi
10.1016/s0165-5728(86)80008-xsubject
Has Abstractpub_date
1986-09-01 00:00:00pages
247-52issue
3eissn
0165-5728issn
1872-8421pii
S0165-5728(86)80008-Xjournal_volume
12pub_type
杂志文章abstract::To explore the role of circular RNAs (circRNAs) in pediatric anti-N-methyl-d-aspartate (NMDA) receptor encephalitis, we assessed the profiles of circRNAs and mRNAs in blood leukocytes from anti-NMDA receptor encephalitis patients and healthy controls using microarray analysis. 1196 circRNAs and 719 mRNAs (change ≥2, p...
journal_title:Journal of neuroimmunology
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journal_title:Journal of neuroimmunology
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journal_title:Journal of neuroimmunology
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abstract::Cerebral ischaemia is a common occurrence in a range of pathological conditions, including stroke and traumatic brain injury. Two of the components in ischaemia are tissue hypoxia and the release of pro-inflammatory agents such as TNF-alpha. The role of TNF-alpha in an ischaemic/hypoxic episode is still controversial,...
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journal_title:Journal of neuroimmunology
pub_type: 杂志文章
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更新日期:2006-12-01 00:00:00
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journal_title:Journal of neuroimmunology
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journal_title:Journal of neuroimmunology
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journal_title:Journal of neuroimmunology
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journal_title:Journal of neuroimmunology
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更新日期:2014-12-15 00:00:00
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journal_title:Journal of neuroimmunology
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journal_title:Journal of neuroimmunology
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journal_title:Journal of neuroimmunology
pub_type: 杂志文章
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更新日期:2013-11-15 00:00:00
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journal_title:Journal of neuroimmunology
pub_type: 杂志文章
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更新日期:2012-05-15 00:00:00
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journal_title:Journal of neuroimmunology
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journal_title:Journal of neuroimmunology
pub_type: 更正并重新发布的文章,杂志文章
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更新日期:2000-08-01 00:00:00
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journal_title:Journal of neuroimmunology
pub_type: 杂志文章,随机对照试验
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journal_title:Journal of neuroimmunology
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journal_title:Journal of neuroimmunology
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journal_title:Journal of neuroimmunology
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journal_title:Journal of neuroimmunology
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journal_title:Journal of neuroimmunology
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journal_title:Journal of neuroimmunology
pub_type: 杂志文章,评审
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journal_title:Journal of neuroimmunology
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更新日期:2007-10-01 00:00:00
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journal_title:Journal of neuroimmunology
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