Correlation between Osteoprotegerin Levels and Antiphospholipid Syndrome Parameters.

abstract：BACKGROUND:Currently, more than 45 mathematical formulas based on simple red blood cell (RBC) parameters have been proposed for differentiating between iron deficiency and thalassemia in microcytic anemia, of which 20 are relatively new and have not been thoroughly independently verified. The study goal was to verify t...

journal_title：Laboratory medicine

authors： Hoffmann JJML,Urrechaga E

更新日期：2020-11-02 00:00:00

abstract：:Extremely low hemoglobin A1c (HbA1c) results below reference range are rare, and the causes and clinical implications associated with low HbA1c results are not well understood among clinical laboratorians. A case of extremely low HbA1c results was reported, in which liver cirrhosis, subacute hemorrhage and recent tran...

journal_title：Laboratory medicine

authors： Wang P

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Knowledge of transfusion medicine is the key element of better transfusion practices. This deficit observed at the blood bank end on daily basis exposing the patients for redundant risk. We assessed the knowledge of transfusion medicine among post intern doctors. OBJECTIVE:To assess the knowledge of transfu...

journal_title：Laboratory medicine

authors： Kumarage S,Fernando R,Gunasekara L

更新日期：2017-02-01 00:00:00

abstract：:Cell-derived microparticles (MPs) are small fragments released from various cells when they are activated or undergo apoptosis. In the field of transfusion medicine, a number of studies have documented increased levels of MPs in blood products, which have been associated with multiple factors, including donor variabil...

journal_title：Laboratory medicine

authors： Noulsri E

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:To evaluate broad-range 16S ribosomal DNA (rDNA) polymerase chain reaction (PCR) as a rapid screening tool to detect bacterial contamination of stem-cell products. METHODS:We performed the evaluation using whole blood spiked with serially diluted bacterial-type strains. Detection sensitivity was defined as t...

journal_title：Laboratory medicine

authors： Tokuno O,Hayakawa A,Yanai T,Mori T,Ohnuma K,Tani A,Minami H,Sugimoto T

更新日期：2015-01-01 00:00:00

abstract：:Caspases play a vital role during apoptosis. In addition to apoptosis, caspases play a role in cytokine gene induction and work to inhibit apoptosis. In order for individuals to thrive with useful tissue growth, the rate of cell growth and division must surpass the rate of cell division. It is well established that ex...

journal_title：Laboratory medicine

authors： Gupta A,Yo J,Huang G,Soong L,Dong J

更新日期：2018-03-21 00:00:00

abstract：OBJECTIVE:Auramine-phenol stain was compared with Kinyoun's acid-fast stain to detect coccidia parasites in fecal samples from immunocompromised patients. The comparison was based on the number of detected cases, sensitivity, specificity, time required for the procedure, ease of use, interpretation, and cost. METHODS:...

journal_title：Laboratory medicine

authors： Abou El-Naga IF,Gaafar MR

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Oxidative stress has been associated with the progression of atherosclerosis and activation of genes that lead to increased deposition of proteins in the extracellular matrix. Bone sialoprotein (BSP) and osteonectin are proteins involved in the initiation and progression of vascular calcification. OBJECTIVE...

journal_title：Laboratory medicine

authors： Farrokhi E,Samani KG,Chaleshtori MH

更新日期：2014-10-01 00:00:00

abstract：:Storage pool deficiency (SPD) is a group of rare platelet disorders that result from deficiencies in α-granules, δ-granules, or both. One type of α-SPD is gray platelet syndrome (GPS), caused by mutations in the neurobeachin-like 2 (NBEAL2) gene that results in a bleeding diathesis, thrombocytopenia, splenomegaly, and...

journal_title：Laboratory medicine

authors： Riley R,Khan A,Pai S,Warmke L,Winkler M,Gunning W

更新日期：2019-10-10 00:00:00

abstract：BACKGROUND:The University of Maryland Medical System, like all other medical systems, is faced with providing the highest quality care in an environment of increased demands and competition for resources. Some responses to this pressure include improved integration, coordination, and efficiency. Laboratory integration ...

journal_title：Laboratory medicine

authors： Cook J

更新日期：2017-02-01 00:00:00

abstract：Objective:To assess the effects of depression and anxiety on serum cytokine levels in patients with chronic hepatitis B (CHB) infection. Methods:In this cross-sectional study, 60 healthy control individuals and 60 patients with CHB participated after filling out standard questionnaires. We examined their serum interle...

journal_title：Laboratory medicine

authors： Bahramabadi R,Fathollahi MS,Hashemi SM,Arababadi AS,Arababadi MS,Yousefi-Daredor H,Bidaki R,Khaleghinia M,Bakhshi MH,Yousefpoor Y,Torbaghan YE,Arababadi MK

更新日期：2017-12-22 00:00:00

abstract：:Waldenström macroglobulinemia (WM) is a form of lymphoplasmacytic lymphoma that can cause hyperviscosity syndrome due to unchecked monoclonal antibody production. Some patients are also found to have associated cryoglobulinemia, which can cause systemic complications including vasculitis, renal disease, and pulmonary ...

journal_title：Laboratory medicine

authors： Beech C,Kumar D,Hendrickson J,Perincheri S,Tormey C,Bahar B

更新日期：2019-07-16 00:00:00

abstract：PATIENT:44-year-old white woman. CHIEF COMPLAINTS:Cramping, nausea, shortness of breath, visual disturbances ("seeing yellow dots"). MEDICAL HISTORY:Status asthmticus, tobacco use, hypertension, migraines. PRINCIPLE LABORATORY FINDINGS:TABLES 1-7, FIGURES 1-4: . ...

journal_title：Laboratory medicine

authors： Bashiti O

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:To establish a new indicator derived from reticulocyte hemoglobin (Ret-He) content and red blood cell (RBC) indices for screening for iron deficiency anemia (IDA) in an area in whch thalassemia is prevalent. METHODS:Blood specimens from 304 women aged between 18 and 30 years residing in northeast Thailand we...

journal_title：Laboratory medicine

authors： Jamnok J,Sanchaisuriya K,Chaitriphop C,Sanchaisuriya P,Fucharoen G,Fucharoen S

更新日期：2020-09-01 00:00:00

abstract：:We report a case of a false-positive HIV result in an apparently healthy pregnant woman. Since no prenatal HIV testing had been performed, we screened for HIV reactivity utilizing the Architect HIV-Ag/Ab Combo assay. Results obtained were inconsistent in that they were repeatedly HIV reactive on a single serum sample ...

journal_title：Laboratory medicine

authors： Akl P,Blick KE

更新日期：2014-07-01 00:00:00

abstract：Objective:To determine the effect of presence of high concentrations of nicotinamide adenine dinucleotide (NADH)- and nicotinamide adenine dinucleotide phosphate (NADPH)-consuming enzymes on the accuracy of glutamate dehydrogenase (GLDH) assay for ammonia. Methods:We measured ammonia concentrations using GLDH and NADH...

journal_title：Laboratory medicine

authors： Vodenicarovova M,Skalska H,Holecek M

更新日期：2017-11-08 00:00:00

abstract：Background:When unpredicted surgical blood loss occurs, it is essential that blood arrive from the blood bank in a timely manner. Objective:To evaluate the turnaround time (TAT) for red blood cells (RBCs) from the blood bank to the operating suite. Cases with delayed TATs were further analyzed to determine potential c...

journal_title：Laboratory medicine

authors： Lee AJ,Kim SG

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:To determine and optimize the sensitivity of the CellaVision DM96 automated image-analysis system in detecting platelet (PLT) clumps on blood smears and to assess the reliability of the traditional laboratory practice of examining only the feather edge of the smear for PLT clumps. METHODS:We processed 102 bl...

journal_title：Laboratory medicine

authors： Gulati G,Uppal G,Florea AD,Gong J

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:Because of the rapidly emerging SARS-CoV-2 pandemic and its wide public health challenges, rapid diagnosis is essential to decrease the spread. Antigen-based rapid detection tests are available; however, insufficient data about their performance are available. METHODS:The lateral-flow immunochromatographic B...

journal_title：Laboratory medicine

authors： Abdelrazik AM,Elshafie SM,Abdelaziz HM

更新日期：2020-12-07 00:00:00

abstract：:Antinuclear antibodies (ANAs) are autoantibodies that attack self-proteins within cell nucleus structures; their presence in serum may indicate an autoimmune disease. Also, positive ANA test results have been obtained in chronic infectious diseases, cancers, medication-related adverse events, and even healthy individu...

journal_title：Laboratory medicine

authors： Sur LM,Floca E,Sur DG,Colceriu MC,Samasca G,Sur G

更新日期：2018-07-05 00:00:00

abstract：PATIENT:66-year-old ethnic Egyptian man. CHIEF COMPLAINT:Hematuria. HISTORY OF PRESENT ILLNESS:The patient had a history of multiple episodes of gross hematuria for the past 5 years. Because the hematuria usually resolved on its own, he did not seek medical attention during that time. Bladder cancer was suspected. P...

journal_title：Laboratory medicine

authors： Zepeda CM,Coffey KH

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Single-vial fecal immunochemical testing (FIT) is an accepted method of colorectal cancer (CRC) screening. The available 3-vial FIT data set allows for comparison of colonoscopy results using various screening methods. OBJECTIVE:To determine the optimal number of vials for a strong FIT-screening program by ...

journal_title：Laboratory medicine

authors： Hancock JA,Palmer GA

更新日期：2019-07-16 00:00:00

abstract：OBJECTIVE:Tyrosine kinase inhibitors (TKIs) are considered standard first-line treatment in patients with chronic myeloid leukemia. Because ABL kinase domain mutations are the most common causes of treatment resistance, their prevalence and assessment during treatment may predict subsequent response to therapy. METHOD...

journal_title：Laboratory medicine

authors： Shojaei M,Rezvani H,Azarkeivan A,Poopak B

更新日期：2020-08-21 00:00:00

abstract：Background:Anti-phospholipase A2 receptor (anti-PLA2R) is a promising biomarker for diagnosis, activity evaluation, therapy monitoring, and prognostic estimation of primary membranous neuropathy (pMN). Difference in methodology may be one cause of the discrepancy in anti-PLA2R-positive percentages in reported studies. ...

journal_title：Laboratory medicine

authors： Li W,Guo Y,Zhang Z,Zhang F,Liu X,Ji X,Liu L,Wang H

更新日期：2018-10-11 00:00:00

abstract：OBJECTIVE:Platelet counts generated by automated analyzers on blood specimens that contain platelet clumps are often inaccurate and require verification by blood-smear review. In this study, we assessed the reliability of the Sysmex XE-5000 instrument to detect platelet clumps. METHOD:We reviewed automated complete bl...

journal_title：Laboratory medicine

authors： Hawkins J,Gulati G,Uppal G,Gong J

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Encephalitis is caused by infection, immune mediated diseases, or primary inflammatory diseases. Of all the causative infectious pathogens, 90% are viruses or bacteria. Granulomatous amoebic encephalitis (GAE), caused by Balamuthia mandrillaris, is a rare but life-threatening disease. Diagnosis and therapy a...

journal_title：Laboratory medicine

authors： Yang Y,Hu X,Min L,Dong X,Guan Y

更新日期：2020-03-10 00:00:00

abstract：:Maintaining an in-compliance clinical laboratory takes continuous awareness and review of standards, regulations, and best practices. A strong quality assurance program and well informed leaders who maintain professional networks can aid in this necessary task. This article will discuss a process that laboratories can...

journal_title：Laboratory medicine

authors： Byrne KM,Levy KY,Reese EM

更新日期：2016-05-01 00:00:00

abstract：PATIENT:78-year-old African-American man. PAST MEDICAL HISTORY:Chronic lymphocytic leukemia first diagnosed in 2003, with a subsequent relapse in 2006 and another in 2010. HISTORY OF PRESENT ILLNESS:In late 2011, the patient was admitted to the hospital for cholelithiasis, at which time his treating physician inciden...

journal_title：Laboratory medicine

authors： Sartori A,Staley B,Skipper A

更新日期：2014-07-01 00:00:00

abstract：:The COVID-19 pandemic has led to a major setback in both the health and economic sectors across the globe. The scale of the problem is enormous because we still do not have any specific anti-SARS-CoV-2 antiviral agent or vaccine. The human immune system has never been exposed to this novel virus, so the viral interact...

journal_title：Laboratory medicine

authors： Sahu KK,Siddiqui AD,Cerny J

更新日期：2021-01-04 00:00:00

abstract：OBJECTIVE:To investigate the expression level and clinical significance of microRNA-155 (miR-155) in bladder cancer. METHODS:We collected 102 pairs of tissue specimens from patients with primary bladder cancer and adjacent normal bladder specimens between March 2008 and May 2013. Quantitative real-time polymerase chai...

journal_title：Laboratory medicine

authors： Wang H,Men CP

更新日期：2015-04-01 00:00:00