Abstract:
:Recent studies have identified the important role of cancer stem cells (CSCs) in carcinogenesis and relapse. However, with respect to multistage cancer metastasis, the role of CSCs has not been well-defined. In several human cancers, data showed that some phenotypic subsets of CSCs were responsible for cancer metastasis. In this review, we surveyed recent advances in the role and mechanism of metastatic CSCs.
journal_name
Cancer Epidemioljournal_title
Cancer epidemiologyauthors
Wang X,Zhu Y,Ma Y,Wang J,Zhang F,Xia Q,Fu Ddoi
10.1016/j.canep.2012.07.007subject
Has Abstractpub_date
2013-02-01 00:00:00pages
60-3issue
1eissn
1877-7821issn
1877-783Xpii
S1877-7821(12)00104-Xjournal_volume
37pub_type
杂志文章,评审abstract:BACKGROUND:New therapeutic options have led to substantial increases in survival expectations of patients with non-Hodgkin lymphoma (NHL) in recent years. In contrast to many malignancies, survival in older patients has improved in NHL at a rate similar to that in younger patients. In the past, the impact of innovation...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2011.08.006
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Data from the Surveillance, Epidemiology, and End Results (SEER) revealed that the incidence of pediatric cancer in Nebraska exceeded the national average during 2009-2013. Further investigation could help understand these patterns. METHODS:This retrospective cohort study investigated pediatric cancer (0-19...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2017.12.006
更新日期:2018-02-01 00:00:00
abstract:INTRODUCTION:This paper presents race-specific breast cancer mortality rates and the corresponding rate ratios for the 50 largest U.S. cities for each of the 5-year intervals between 2005 and 2014. METHODS:The 50 largest cities in the U.S. were the units of analysis. Numerator data were abstracted from national death ...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2016.07.018
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:For myelodysplastic syndromes (MDS) (formerly known as preleukemia), a diverse group of myeloid neoplasms usually involving anemia in elderly persons, trends in U.S. death rates apparently have not been reported. METHODS:Trends in annual age-standardized rates per 100,000 from 1999 to 2009 were examined for...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2013.05.004
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:The aim of this study was to analyze the properties of the immune cell microenvironment of regional lymph nodes (LNs) positive for lung cancer. METHODS:Twenty-four patients operated on for stages T1 and T2 of the NSCLC, were enrolled in the study. Peripheral blood and LN tissue were obtained from different ...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2009.10.011
更新日期:2009-11-01 00:00:00
abstract:INTRODUCTION:Receptor status determines of breast cancer treatment and prognosis. In a population-based study, we investigated predictors of receptor test receipt. MATERIALS AND METHODS:Invasive breast cancers diagnosed 2006-2008 were abstracted from the National Cancer Registry Ireland. Modified Poisson regression wi...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2015.08.006
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Prostate cancer is the leading type of cancer among men in more developed countries. Incidence trends and survival rates could differ by age groups considering potential differences in the frequency of PSA testing, types of cancers and medical management. Our objective was to compare incidence trends and sur...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2018.07.007
更新日期:2018-10-01 00:00:00
abstract::French uterine cancer recordings in death certificates include 60% of "uterine cancer, Not Otherwise Specified (NOS)"; this hampers the estimation of mortalities from cervix and corpus uteri cancers. The aims of this work were to study the reliability of uterine cancer recordings in death certificates using a case mat...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2010.10.008
更新日期:2011-06-01 00:00:00
abstract:INTRODUCTION:Brazil has high rates of caesarean sections, which has been suggested as a risk factor for acute lymphoblastic leukaemia (ALL). In addition, some pre- and postnatal conditions have been identified as relevant in the etiology of ALL. OBJECTIVES:Investigate the association of caesarean sections, pre- and po...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2020.101851
更新日期:2020-12-01 00:00:00
abstract:INTRODUCTION:In the last ten to twenty years, a stabilization or decline in colorectal cancer (CRC) incidence has been observed in some countries across the world but not in Spain. Our objective here is to assess the gender-specific CRC spatio-temporal pattern in the health areas of Navarre, a Spanish province, during ...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2011.10.004
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVES:This paper aims to determine whether racial disparities exist in hospitalization outcomes among African-American and White hospitalized prostate cancer patients in the United States. We evaluated racial differences among matched groups of patients in post-operative complications, hospital length of stay and ...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2016.12.001
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Prior work estimating optimal treatment utilisation rates for cervical cancer has focused on radiotherapy or chemotherapy, using proportions of patients with clinical indications for specific treatment strategies which were obtained from the published literature. OBJECTIVES:To estimate optimal uptake rates ...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2015.04.009
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Age-standardization is vital in international comparison studies of cancer patient survival, but standard approaches can fail to produce estimates in the case of sparsity. METHODS:The purpose of this paper is to demonstrate that using a standardization pre-weighting approach is a viable alternative approach...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2020.101745
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVES:A prospective study to estimate benefits due to fecal occult blood tests for colorectal cancer are carried out for both males and females, under different screening frequencies. METHODS:We apply the statistical method developed by Wu et al. (2007) [1] using the Minnesota colorectal cancer study group data, ...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2009.08.001
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND:The 'Two Week Wait' policy aims to ensure patients with suspected cancer are seen within two weeks of referral. However, patient non-attendance can result in this target being missed. This study aimed to identify predictors of non-attendance; and analyse the relationship between attendance and outcomes inclu...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2019.101588
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:We assessed the association between diabetes and breast cancer and whether physical activity modified the effect of diabetes on breast cancer in Hispanic women. METHODS:We used data from a case-control study of breast cancer among Hispanic women aged 30-79 conducted between 2003 and 2008 on the Texas-Mexico bo...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2010.06.001
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:With linked register and cause of death data becoming more accessible than ever, competing risks methodology is being increasingly used as a way of obtaining "real world" probabilities of death broken down by specific causes. It is important, in terms of the validity of these studies, to have accurate cause ...
journal_title:Cancer epidemiology
pub_type: 杂志文章,评审
doi:10.1016/j.canep.2012.08.012
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:We developed a novel method of methylation-specific PCR (MSP) using immunoprecipitation with anti-histone antibody (IP-MSP) to efficiently detect serum methylated DNA tightly bound to de-acetylated histones. MATERIALS AND METHODS:The detection limit of IP-MSP for p16 methylation was determined with a standa...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2010.01.004
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:Little is known about the epidemiology and etiology of Waldenstrom macroglobulinemia (WM). Despite several studies of the relation between family history and B-cell disorders and WM, family history of non-hematologic cancers has not been systematically investigated. We thus examined associations of family hi...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2011.10.010
更新日期:2012-06-01 00:00:00
abstract:INTRODUCTION:Folic acid fortification and supplementation to prevent neural tube defects has led to concerns regarding increased risk of colorectal cancer. The results of existing studies have been inconclusive. The purpose was to examine the relationship between level of folate intake and the incidence of colorectal c...
journal_title:Cancer epidemiology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.canep.2010.11.004
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:Recent years have seen increased interest in the role of neighborhood factors in chronic diseases such as cancers. Less is known about the role of neighborhood factors beyond individual demographics such as age or education. It is particularly important to examine neighborhood effects on health among African...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2019.101666
更新日期:2020-02-01 00:00:00
abstract::Nibrin and DNA repair protein XRCC3 are involved in DNA double-strand break repair. We genotyped seven tagging SNPs in these genes (rs1805794, rs709816; rs1063054; rs7141928, rs1799794, rs861530, rs861539) with the aim to analyse their association with acute lymphoblastic leukaemia (ALL), a disease, that is characteri...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2014.08.002
更新日期:2014-10-01 00:00:00
abstract:INTRODUCTION:It is unknown whether a normal range, diagnostic serum prostate specific antigen (PSA) level's influence on prostate cancer specific mortality (PCSM) is dependent upon digital rectal examination (DRE) findings. METHODS:Between 2004 and 2007, 9081 men diagnosed with non-palpable (T1c, N=1710) or palpable (...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2014.07.007
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:Chewing areca (betel) nut has been deemed carcinogenic. The practice has become a public health concern in Micronesia. The Children's Healthy Living (CHL) Program included an areca (betel) nut questionnaire in a survey of household characteristics in the Freely Associated States (FAS). This paper describes a...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2017.07.009
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:The distinctive racial/ethnic and geographic distribution of multiple myeloma (MM) suggests that both family history and environmental factors may contribute to its development. METHODS:A hospital-based case-control study consisting of 220 confirmed MM cases and 220 individually matched patient controls, by...
journal_title:Cancer epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.canep.2012.05.002
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Cow's milk contain phytoestrogens especially equol depending on the composition of the feed ration. However, it is unknown whether milk differing in equol exhibits different estrogenicity in model systems and thereby potentially in humans as milk consumers. METHODS:The estrogenicity of high and low equol mi...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2009.04.003
更新日期:2009-07-01 00:00:00
abstract:AIM:We studied whether incidence of all cancer sites combined was associated with the radiation exposure due to fallout from the Chernobyl accident in Finland. An emphasis was on the first decade after the accident to assess the suggested "promotion effect". METHODS:The segment of Finnish population with a stable resi...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2013.05.006
更新日期:2013-10-01 00:00:00
abstract::South Asian countries are facing a hidden breast cancer epidemic. A significant proportion of the breast cancer cases occur in premenopausal women. Knowledge of the various aspects of breast cancer in different geographical regions is limited in South Asia. In this article, we review the Bangladeshi perspective of the...
journal_title:Cancer epidemiology
pub_type: 杂志文章,评审
doi:10.1016/j.canep.2014.08.004
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:Although, biologically plausible evidence has implicated coffee, tea and caffeine with carcinogenesis, there is a paucity of data on their associations with risk of cancer among Canadian women. Hence, we assessed their associations with risk of breast, endometrial and ovarian cancers within this population. ...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2018.07.013
更新日期:2018-10-01 00:00:00
abstract::The miR-451 was found to be frequently down-regulated in tumors, indicating that miR-451 could play an important role in carcinogenesis. This study uncovered the mechanism by which the miR-451 functions as a tumor suppressor. The target genes of miR-451 were determined using target gene prediction softwares. Then the ...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2013.12.005
更新日期:2014-02-01 00:00:00