Abstract：
:Nibrin and DNA repair protein XRCC3 are involved in DNA double-strand break repair. We genotyped seven tagging SNPs in these genes (rs1805794, rs709816; rs1063054; rs7141928, rs1799794, rs861530, rs861539) with the aim to analyse their association with acute lymphoblastic leukaemia (ALL), a disease, that is characterised by elevated genetic instability. Study consisted of 460 paediatric ALL cases and 552 healthy controls. For selection of DNA sequence variants we employed SNP-tagging approach, incorporating the HAPMAP CEU reference panel data. We did not find association of analysed and tagged SNPs and derived haplotypes with the ALL risk thus did not confirm the hypothesis that analysed DNA recombination repair variants account for increased susceptibility to ALL.
journal_name
Cancer Epidemioljournal_title
Cancer epidemiologyauthors
Smolkova B,Dusinska M,Hemminki Kdoi
10.1016/j.canep.2014.08.002subject
Has Abstractpub_date
2014-10-01 00:00:00pages
563-8issue
5eissn
1877-7821issn
1877-783Xpii
S1877-7821(14)00142-8journal_volume
38pub_type
杂志文章abstract：BACKGROUND:Age-standardization is vital in international comparison studies of cancer patient survival, but standard approaches can fail to produce estimates in the case of sparsity. METHODS:The purpose of this paper is to demonstrate that using a standardization pre-weighting approach is a viable alternative approach...
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pub_type： 杂志文章
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更新日期：2020-08-01 00:00:00
abstract：OBJECTIVE:We explored whether smoking is associated with cancer screening behaviors. METHODS:We used data from the 2007 Florida Behavioral Risk Factor Surveillance System and the Florida Tobacco Callback Survey to examine screening behaviors related to four cancer types (breast, cervical, prostate, and colorectal). Us...
journal_title：Cancer epidemiology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.canep.2010.06.017
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abstract：BACKGROUND:We aimed to report, for the first time, the results of the Iranian National Population-based Cancer Registry (INPCR) for the year 2014. METHODS:Total population of Iran in 2014 was 76,639,000. The INPCR covered 30 out of 31 provinces (98% of total population). It registered only cases diagnosed with maligna...
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pub_type： 历史文章,杂志文章
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更新日期：2019-08-01 00:00:00
abstract：INTRODUCTION:It is unknown whether a normal range, diagnostic serum prostate specific antigen (PSA) level's influence on prostate cancer specific mortality (PCSM) is dependent upon digital rectal examination (DRE) findings. METHODS:Between 2004 and 2007, 9081 men diagnosed with non-palpable (T1c, N=1710) or palpable (...
journal_title：Cancer epidemiology
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doi：10.1016/j.canep.2014.07.007
更新日期：2014-10-01 00:00:00
abstract：BACKGROUND:Despite being a well-documented phenomenon, seasonal variation in the incidence of cutaneous melanoma is poorly understood, and data on the seasonality of melanoma survival are scarce. We sought to explore the seasonal variation in melanoma incidence and survival in Belgium and to assess the characteristics ...
journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2015.07.003
更新日期：2015-10-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to compare quality performance of the first colorectal cancer (CRC) screening campaigns (C) with the OC Sensor® Faecal Immunological Test (FIT) (C7 from 2016 to 2017) and the Hemoccult® guaiac-based test (C1 from 2004 to 2006). METHODS:The participation rate of the eligible populati...
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pub_type： 杂志文章
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更新日期：2020-12-01 00:00:00
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journal_title：Cancer epidemiology
pub_type： 杂志文章
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更新日期：2018-04-01 00:00:00
abstract：:DNA repair plays a pivotal role in maintaining genomic integrity with over 130 genes involved in various repair pathways that include base excision repair, nucleotide excision repair, double strand break repair and DNA mismatch repair. Polymorphisms within genes that are involved in these processes have been widely re...
journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2011.09.003
更新日期：2012-04-01 00:00:00
abstract：BACKGROUND:Leukaemia is a heterogeneous disease in which haematopoietic progenitor cells acquire genetic lesions that lead to a block in differentiation, increased self-renewal, and unregulated proliferation. The enzyme 5,10-methylenetetrahydrofolate reductase (MTHFR), involved in folate metabolism, plays a crucial rol...
journal_title：Cancer epidemiology
pub_type： 杂志文章
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更新日期：2012-08-01 00:00:00
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journal_title：Cancer epidemiology
pub_type： 杂志文章
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更新日期：2020-02-01 00:00:00
abstract：BACKGROUND:Survival has steadily improved for major cancer types in most parts of the world. We compared all-cause mortality between foreign-born and Sweden-born residents of Sweden who were diagnosed with cancer of the colon, lung, stomach, prostate, breast, cervix, and all site. METHODS:We used Swedish national vita...
journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2015.06.003
更新日期：2015-08-01 00:00:00
abstract：BACKGROUND:The cancer research groups of the National Cancer Institute's National Clinical Trials Network have a history of successful conduct of large randomized phase III trials of chemoprevention for cancer. An important question for funding agencies is whether the conduct of large chemoprevention trials provides st...
journal_title：Cancer epidemiology
pub_type： 杂志文章
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更新日期：2018-08-01 00:00:00
abstract：BACKGROUND:Chromosome 19q13.3 has been identified as one of the regions that associate with cancer risk in previous studies. METHODS:We systematically examined the 70.772kb region comprising four genes on chromosome 19q13.3 among Chinese using the haplotype-tagging SNP (htSNP) approach and the HapMap platform. The stu...
journal_title：Cancer epidemiology
pub_type： 杂志文章
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更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:Little is known about the epidemiology and etiology of Waldenstrom macroglobulinemia (WM). Despite several studies of the relation between family history and B-cell disorders and WM, family history of non-hematologic cancers has not been systematically investigated. We thus examined associations of family hi...
journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2011.10.010
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:The 'Two Week Wait' policy aims to ensure patients with suspected cancer are seen within two weeks of referral. However, patient non-attendance can result in this target being missed. This study aimed to identify predictors of non-attendance; and analyse the relationship between attendance and outcomes inclu...
journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2019.101588
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:This study examined the incidence of skeletal-related events (SRE) among patients with breast cancer (BC)- or prostate cancer (PC)-induced bone metastasis or multiple myeloma (MM) based on a population-based, 12-year healthcare database. METHODS:Patients aged ≥18 years with bone metastasis from BC or PC or ...
journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2019.05.013
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND:For myelodysplastic syndromes (MDS) (formerly known as preleukemia), a diverse group of myeloid neoplasms usually involving anemia in elderly persons, trends in U.S. death rates apparently have not been reported. METHODS:Trends in annual age-standardized rates per 100,000 from 1999 to 2009 were examined for...
journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2013.05.004
更新日期：2013-10-01 00:00:00
abstract：AIM:Our study aim was to investigate the degree of adherence to international recommendations for cutaneous melanoma pathology reports at the population level by a EUROCARE high resolution study. METHODS:The availability of nine characteristics - predominant cell type, tumour-infiltrating lymphocytes, mitotic index, h...
journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2015.01.016
更新日期：2015-06-01 00:00:00
abstract：BACKGROUND:Implementation of mammography screening and advances in breast cancer treatment are considered as main reasons for the decline in breast cancer mortality observed in many industrialized countries during the past two decades. The purpose of this study was to provide a comprehensive assessment of trends in bre...
journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2011.01.008
更新日期：2011-10-01 00:00:00
abstract：BACKGROUND:Esophageal cancer is one of the most commonly diagnosed malignant tumors in China. The aim of this study was to provide the representative and comprehensive informations about the long-term mortality trends of this disease in China between 1987 and 2009, using joinpoint regression and generalized additive mo...
journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2011.12.003
更新日期：2012-04-01 00:00:00
abstract：:Pancreatic cancer is a leading cause of cancer-related deaths worldwide. Methylation of DNA may influence risk or be a marker of early disease. The aim of this study was to measure the association between methylation of three DNA repetitive elements in white blood cell (WBC) DNA and pancreatic cancer. DNA from WBCs of...
journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2014.08.006
更新日期：2014-10-01 00:00:00
abstract：INTRODUCTION:Obesity is a well-established risk factor for postmenopausal breast cancer, but mechanisms underlying the association are unclear. Adipocyte-derived, cytokine-like adipokines have been suggested as contributory factors. To evaluate their association with breast cancer risk factors and breast cancer risk, w...
journal_title：Cancer epidemiology
pub_type： 杂志文章
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更新日期：2010-10-01 00:00:00
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journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2013.07.008
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:DNA repair gene polymorphisms can contribute to susceptibility of human cancer, including gastric cancer. Three single nucleotide polymorphisms (SNPs) of xeroderma pigmentosum group D (XPD) and X-ray repair cross complement 1 (XRCC1) genes were genotyped in gastric cancer and control subjects in a population...
journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2010.08.008
更新日期：2011-04-01 00:00:00
abstract：:Background Lung cancer mortality accounts for over 266,000 deaths in the European Union (EU) every year, most of them attributed to smoking. The aim of this study was to estimate the prevalence of the adult population at high risk of developing lung cancer in the EU in 2014. Methods This is a cross-sectional study. We...
journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2018.10.007
更新日期：2018-12-01 00:00:00
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journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2019.06.007
更新日期：2019-08-01 00:00:00
abstract：:We examined the prevalence of HR- and LR-HPV by Linear Array genotyping test in 299 women aged 18-63 years who consecutively visited Molise Region main hospitals for routine Pap smear between February and August 2008. Ninety women were positive for any HPV (30.1%), and 66 for any HR-HPV (22.1%). The most prevalent HR-...
journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2009.12.010
更新日期：2010-04-01 00:00:00
abstract：INTRODUCTION:Antigenic stimulation is a proposed aetiologic mechanism for many haematological malignancies. Limited evidence suggests that community-acquired infections may increase the risk of acute myeloid leukaemia (AML) and myelodysplastic syndrome (MDS). However, associations with other myeloid malignancies includ...
journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2013.10.009
更新日期：2014-02-01 00:00:00
abstract：BACKGROUND:Global variations in the frequency of the major sub-types of lymphoma have been reported. However, studies on different sub-types of adult malignant lymphoma had never been conducted in Mashhad, Iran. In this paper, we aimed to identify the major sub-types of malignant lymphoma in our area and compare the di...
journal_title：Cancer epidemiology
pub_type： 杂志文章
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更新日期：2011-02-01 00:00:00
abstract：AIM:The prevalence of hysterectomy is decreasing worldwide. It is not clear whether changes in the population at risk (women with intact uteruses) have contributed to an increased uterine cancer incidence. This study aims to assess the effect of changing trends in hysterectomy prevalence on uterine cancer incidence in ...
journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2019.02.008
更新日期：2019-04-01 00:00:00
