Abstract:
BACKGROUND:Data from the Surveillance, Epidemiology, and End Results (SEER) revealed that the incidence of pediatric cancer in Nebraska exceeded the national average during 2009-2013. Further investigation could help understand these patterns. METHODS:This retrospective cohort study investigated pediatric cancer (0-19 years old) age adjusted incidence rates (AAR) in Nebraska using the Nebraska Cancer Registry. SEER AARs were also calculated as a proxy for pediatric cancer incidence in the United States (1990-2013) and compared to the Nebraska data. Geographic Information System (GIS) mapping was also used to display the spatial distribution of cancer in Nebraska at the county level. Finally, location-allocation analysis (LAA) was performed to identify a site for the placement of a medical center to best accommodate rural pediatric cancer cases. RESULTS:The AAR of pediatric cancers was 173.3 per 1,000,000 in Nebraska compared to 167.1 per 1,000,000 in SEER. The AAR for lymphoma was significantly higher in Nebraska (28.1 vs. 24.6 per 1,000,000; p = 0.009). For the 15-19 age group, the AAR for the 3 most common pediatric cancers were higher in Nebraska (p < 0.05). Twenty-three counties located >2 h driving distance to care facilities showed at least a 10% higher incidence than the overall state AAR. GIS mapping identified a second potential treatment site that would alleviate this geographic burden. CONCLUSIONS:Regional differences within Nebraska present a challenge for rural populations. Novel use of GIS mapping to highlight regional differences and identify solutions for access to care issues could be used by similar states.
journal_name
Cancer Epidemioljournal_title
Cancer epidemiologyauthors
Farazi PA,Watanabe-Galloway S,Westman L,Rettig B,Hunt P,Cammack R,Sparks JW,Coulter DWdoi
10.1016/j.canep.2017.12.006subject
Has Abstractpub_date
2018-02-01 00:00:00pages
83-90eissn
1877-7821issn
1877-783Xpii
S1877-7821(17)30205-9journal_volume
52pub_type
杂志文章abstract:BACKGROUND:A new cancer patient pathway for patients presenting with non-specific signs and symptoms (NSSC-CPP) was implemented nationally in Denmark in 2012. This study aims to describe, on a national level, the characteristics of patients referred to the Danish NSSC-CPP, and to estimate the prevalence and distributio...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2017.08.003
更新日期:2017-10-01 00:00:00
abstract:AIM:We have reported the in vitro and in vivo anticancer activities of 6-(methylsulfinyl)hexyl isothiocyanate (6-MITC) derived from a Japanese spice, wasabi. In order to obtain some clues about the mechanism of the anticancer activity, we have studied the effect of alkyl isothiocyanates (MITCs) on protein kinase activi...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2009.08.009
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND:The distinctive racial/ethnic and geographic distribution of multiple myeloma (MM) suggests that both family history and environmental factors may contribute to its development. METHODS:A hospital-based case-control study consisting of 220 confirmed MM cases and 220 individually matched patient controls, by...
journal_title:Cancer epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.canep.2012.05.002
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Implementation of mammography screening and advances in breast cancer treatment are considered as main reasons for the decline in breast cancer mortality observed in many industrialized countries during the past two decades. The purpose of this study was to provide a comprehensive assessment of trends in bre...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2011.01.008
更新日期:2011-10-01 00:00:00
abstract:PURPOSE:To describe the sex-specific incidence rates and the male-to-female incidence-rate ratios (IRRs) of different cancer types, and to explore the corresponding sex disparities in an area of Eastern China. METHODS:We used data from the Cancer Registry in Jiashan County, and calculated the sex-specific age-standard...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2017.07.013
更新日期:2017-10-01 00:00:00
abstract:INTRODUCTION:In the Netherlands, breast cancer patients are treated and followed at least 5 years after diagnosis. Furthermore, all women aged 50-74 are invited biennially for mammography by the nationwide screening programme. The relation between the outpatient follow-up (follow-up visits in the outpatient clinic for ...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2013.09.003
更新日期:2013-12-01 00:00:00
abstract:BACKGROUND:With linked register and cause of death data becoming more accessible than ever, competing risks methodology is being increasingly used as a way of obtaining "real world" probabilities of death broken down by specific causes. It is important, in terms of the validity of these studies, to have accurate cause ...
journal_title:Cancer epidemiology
pub_type: 杂志文章,评审
doi:10.1016/j.canep.2012.08.012
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:The 'Two Week Wait' policy aims to ensure patients with suspected cancer are seen within two weeks of referral. However, patient non-attendance can result in this target being missed. This study aimed to identify predictors of non-attendance; and analyse the relationship between attendance and outcomes inclu...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2019.101588
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:This study examined the incidence of skeletal-related events (SRE) among patients with breast cancer (BC)- or prostate cancer (PC)-induced bone metastasis or multiple myeloma (MM) based on a population-based, 12-year healthcare database. METHODS:Patients aged ≥18 years with bone metastasis from BC or PC or ...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2019.05.013
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVES:To compare the trends in prostate cancer incidence, treatment with curative intent and mortality across regions and counties in Norway, and to consider changes in incidence (an indicator for early diagnosis) and treatment with curative intent as explanatory factors for the decreasing prostate cancer mortalit...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2010.04.017
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:The potentially functional polymorphism, rs909253 (+252 G>A), in the intron region of the LT-α (TNF-β) gene has been implicated in the risk of gastric cancer (GC) in some individually published studies, but others have shown inconsistent and inconclusive results. METHODS:We conducted a meta-analysis to asse...
journal_title:Cancer epidemiology
pub_type: 杂志文章,meta分析
doi:10.1016/j.canep.2012.05.014
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:The cancer research groups of the National Cancer Institute's National Clinical Trials Network have a history of successful conduct of large randomized phase III trials of chemoprevention for cancer. An important question for funding agencies is whether the conduct of large chemoprevention trials provides st...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2018.06.005
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Global variations in the frequency of the major sub-types of lymphoma have been reported. However, studies on different sub-types of adult malignant lymphoma had never been conducted in Mashhad, Iran. In this paper, we aimed to identify the major sub-types of malignant lymphoma in our area and compare the di...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2010.09.009
更新日期:2011-02-01 00:00:00
abstract::Cadmium, a human carcinogenic heavy metal, has been reported to be associated with breast cancer risk; however, the results from the epidemiological studies are not always consistent. The objective of this study was to quantitatively summarize the current evidence for the relationship between cadmium exposure and brea...
journal_title:Cancer epidemiology
pub_type: 杂志文章,meta分析
doi:10.1016/j.canep.2016.04.002
更新日期:2016-06-01 00:00:00
abstract::The miR-451 was found to be frequently down-regulated in tumors, indicating that miR-451 could play an important role in carcinogenesis. This study uncovered the mechanism by which the miR-451 functions as a tumor suppressor. The target genes of miR-451 were determined using target gene prediction softwares. Then the ...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2013.12.005
更新日期:2014-02-01 00:00:00
abstract:AIM:Our study aim was to investigate the degree of adherence to international recommendations for cutaneous melanoma pathology reports at the population level by a EUROCARE high resolution study. METHODS:The availability of nine characteristics - predominant cell type, tumour-infiltrating lymphocytes, mitotic index, h...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2015.01.016
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:DNA repair gene polymorphisms can contribute to susceptibility of human cancer, including gastric cancer. Three single nucleotide polymorphisms (SNPs) of xeroderma pigmentosum group D (XPD) and X-ray repair cross complement 1 (XRCC1) genes were genotyped in gastric cancer and control subjects in a population...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2010.08.008
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:Telomeres help maintain chromosomal structure and may influence tumorigenesis. We examined the association between telomere length and skin cancer in a clinic-based case-control study of 198 melanoma cases, 136 squamous cell carcinoma (SCC) cases, 185 basal cell carcinoma (BCC) cases, and 372 healthy control...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2013.02.010
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:The anatomic distribution of advanced colorectal neoplasia is increasingly important for choosing screening strategies and treatment options. We sought to evaluate the impact of repeated screening on the positive predictive value (PPV) for advanced colorectal neoplasia (advanced adenoma, AA, and colorectal c...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2015.09.008
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:To develop a prediction model to quantify the cumulative risk of Second Primary Cancer (SPC) among cancer patients given that they survive their disease. METHODS:A cohort of 293,435 patients based on data from twelve French cancer registries was analyzed. For five first cancer sites, SPC incidence rates wer...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2017.01.001
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVES:A large proportion of patients with cutaneous malignant melanoma (CMM) do not experience excess mortality due to their disease. This group of patients is referred to as the cure proportion. Few studies have examined the possibility of cure for CMM. The aim of this study was to estimate the cure proportion of...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2013.12.006
更新日期:2014-02-01 00:00:00
abstract:AIM:To test the effect of African-American race on cancer specific mortality (CSM) in clear cell metastatic renal cell carcinoma (ccmRCC) and non-ccmRCC. PATIENTS AND METHODS:Within Surveillance, Epidemiology and End Results registry (2001-2014), we identified patients with ccmRCC and non-ccmRCC. We relied on propensi...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2018.04.006
更新日期:2018-06-01 00:00:00
abstract::It is estimated that over half the population of the European Union (EU) is overweight or obese due to an imbalance between energy expenditure and energy intake; this is related to an obesogenic environment of sociocultural, economic and marketing challenges to the control of body weight. Excess body fat is associated...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2015.01.017
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Although, biologically plausible evidence has implicated coffee, tea and caffeine with carcinogenesis, there is a paucity of data on their associations with risk of cancer among Canadian women. Hence, we assessed their associations with risk of breast, endometrial and ovarian cancers within this population. ...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2018.07.013
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVE:To investigate the clinical value in detecting occult primary tumors with (18)F-FDG PET-CT whole body imaging. METHODS:120 patients with unknown primary origin were referred for (18)F-FDG PET-CT whole body imaging. All patients were performed (18)F-FDG PET-CT whole body scan. PET-CT images were interpreted b...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2012.03.002
更新日期:2012-10-01 00:00:00
abstract::Background Lung cancer mortality accounts for over 266,000 deaths in the European Union (EU) every year, most of them attributed to smoking. The aim of this study was to estimate the prevalence of the adult population at high risk of developing lung cancer in the EU in 2014. Methods This is a cross-sectional study. We...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2018.10.007
更新日期:2018-12-01 00:00:00
abstract::In economically developed countries up to 90% of women are prescribed medications, including vitamins and supplements, during pregnancy. Whilst a number of adverse health outcomes in their offspring have been related to prescription drug use, associations with childhood cancer are less clear and most investigations ha...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2014.10.008
更新日期:2015-02-01 00:00:00
abstract:INTRODUCTION:Antigenic stimulation is a proposed aetiologic mechanism for many haematological malignancies. Limited evidence suggests that community-acquired infections may increase the risk of acute myeloid leukaemia (AML) and myelodysplastic syndrome (MDS). However, associations with other myeloid malignancies includ...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2013.10.009
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:The objective of this study is to estimate the gap between smoking prevalence and lung cancer mortality and provide predictions of lung cancer mortality based on previous smoking prevalence. MATERIALS AND METHODS:We used data from the Spanish National Health Surveys (2003, 2006 and 2011) to obtain informati...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2017.04.012
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Asian studies on soft tissue sarcoma (STS) incidence, irrespective of the primary site, are scant. METHODS:STS data were acquired from the population-based 2007-2013 Taiwan Cancer Registry of the Health and Welfare Data Science Center, Taiwan. Histological subtype-, site-, sex-, and age-specific STS inciden...
journal_title:Cancer epidemiology
pub_type: 历史文章,杂志文章
doi:10.1016/j.canep.2019.04.007
更新日期:2019-06-01 00:00:00