Abstract:
OBJECTIVES:A large proportion of patients with cutaneous malignant melanoma (CMM) do not experience excess mortality due to their disease. This group of patients is referred to as the cure proportion. Few studies have examined the possibility of cure for CMM. The aim of this study was to estimate the cure proportion of patients with CMM in a Swedish population. METHODS:We undertook a population-based study of 5850 CMM patients in two Swedish health care regions during 1996-2005. We used flexible parametric cure models to estimate cure proportions and median survival times (MSTs) of uncured by stage, sex, age and anatomical site. RESULTS:Disease stage at diagnosis was the most important factor for the probability of cure, with a cure proportion of approximately 1.0 for stage IA. While the probability of cure decreased with older age, the influence of age was smaller on the MST of uncured. Differences in prognosis between males and females were mainly attributed to differences in cure as opposed to differences in MST of uncured. CONCLUSIONS:This population-based study showed approximately 100% cure among stage IA disease. Almost 50% of patients had stage IA disease and the high cure proportion for this large patient group is reassuring.
journal_name
Cancer Epidemioljournal_title
Cancer epidemiologyauthors
Andersson TM,Eriksson H,Hansson J,Månsson-Brahme E,Dickman PW,Eloranta S,Lambe M,Lambert PCdoi
10.1016/j.canep.2013.12.006subject
Has Abstractpub_date
2014-02-01 00:00:00pages
93-9issue
1eissn
1877-7821issn
1877-783Xpii
S1877-7821(13)00192-6journal_volume
38pub_type
杂志文章abstract:INTRODUCTION:Antigenic stimulation is a proposed aetiologic mechanism for many haematological malignancies. Limited evidence suggests that community-acquired infections may increase the risk of acute myeloid leukaemia (AML) and myelodysplastic syndrome (MDS). However, associations with other myeloid malignancies includ...
journal_title:Cancer epidemiology
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abstract::The miR-451 was found to be frequently down-regulated in tumors, indicating that miR-451 could play an important role in carcinogenesis. This study uncovered the mechanism by which the miR-451 functions as a tumor suppressor. The target genes of miR-451 were determined using target gene prediction softwares. Then the ...
journal_title:Cancer epidemiology
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2014.10.012
更新日期:2015-02-01 00:00:00
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journal_title:Cancer epidemiology
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journal_title:Cancer epidemiology
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2010.09.009
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2018.12.010
更新日期:2019-02-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 历史文章,杂志文章
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更新日期:2019-08-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2019.101657
更新日期:2020-02-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2015.01.016
更新日期:2015-06-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2019.04.001
更新日期:2019-06-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2017.07.009
更新日期:2017-10-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2018.10.007
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pub_type: 杂志文章
doi:10.1016/j.canep.2013.05.004
更新日期:2013-10-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2015.08.002
更新日期:2015-10-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2018.06.005
更新日期:2018-08-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2011.04.005
更新日期:2012-02-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2009.07.011
更新日期:2009-10-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2019.101588
更新日期:2019-12-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.canep.2012.05.002
更新日期:2012-10-01 00:00:00
abstract:AIM:To review and summarize evidence from longitudinal studies on the association between serum 25-hydroxyvitamin D (25(OH)D) and the risk of prostate cancer (PC). METHODS:Relevant prospective cohort studies and nested case-control studies published until July 2009 were identified by systematically searching Ovid Medl...
journal_title:Cancer epidemiology
pub_type: 杂志文章,meta分析
doi:10.1016/j.canep.2009.10.014
更新日期:2009-12-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2010.05.001
更新日期:2010-10-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2015.04.011
更新日期:2015-08-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2020.101707
更新日期:2020-06-01 00:00:00