Abstract:
OBJECTIVE:To investigate whether health insurance affiliation and socioeconomic deprivation is associated with overall cause survival from gastric cancer in a middle-income country. METHODS:All patients resident in the Bucaramanga metropolitan area (Colombia) diagnosed with gastric cancer between 2003 and 2009 (n=1039), identified in the population-based cancer registry, were followed for vital status until 31/12/2013. Kaplan-Meier models provided crude survival estimates by health insurance regime (HIR) and social stratum (SS). Multivariate Cox-proportional hazard models adjusting HIR and SS for sex, age and tumor grade, were performed. RESULTS:Overall 1 and 5 year survival proportions were 32.4% and 11.0%, respectively, varying from 49.3% and 15.8% for patients affiliated to the most generous HIR to 12.9% and 5.3% for unaffiliated patients, and from 41.4% and 20.7% for patients in the highest SS, versus 27.1% and 7.4% for the lowest SS. The multivariate analyses showed type of HIR as well as SS to remain independently associated with survival, with an 11% improvement in survival for each increase in SS subgroup (HR 0.89 (95% CI 0.83; 0.96), and with worse survival in the subsidized (least generous) HIR and unaffiliated patients compared to the contributory HIR (HR subsidized 1.20 (95% CI 1.00; 1.43) and HR not affiliated 2.03 (95% CI 1.48; 2.78)). Of the non-affiliated patients, 60% had died at the time of diagnosis, versus 4-14% of affiliated patients (p<0.0005). CONCLUSIONS:Despite the 'universal' health insurance system, large socioeconomic differences in gastric cancer survival exist in Colombia. Both social stratum and access to effective diagnostic and curative care strongly influence survival.
journal_name
Cancer Epidemioljournal_title
Cancer epidemiologyauthors
de Vries E,Uribe C,Pardo C,Lemmens V,Van de Poel E,Forman Ddoi
10.1016/j.canep.2014.10.012subject
Has Abstractpub_date
2015-02-01 00:00:00pages
91-6issue
1eissn
1877-7821issn
1877-783Xpii
S1877-7821(14)00190-8journal_volume
39pub_type
杂志文章abstract::Background Lung cancer mortality accounts for over 266,000 deaths in the European Union (EU) every year, most of them attributed to smoking. The aim of this study was to estimate the prevalence of the adult population at high risk of developing lung cancer in the EU in 2014. Methods This is a cross-sectional study. We...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2018.10.007
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:One of the potential strategies for preventing cancers is using food-based natural products to induce cytoprotective enzymes including phase II and antioxidative enzymes that act in concert to detoxify and eliminate harmful reactive intermediates formed from carcinogens. The antioxidant response element (ARE...
journal_title:Cancer epidemiology
pub_type: 杂志文章,评审
doi:10.1016/j.canep.2010.06.012
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to compare quality performance of the first colorectal cancer (CRC) screening campaigns (C) with the OC Sensor® Faecal Immunological Test (FIT) (C7 from 2016 to 2017) and the Hemoccult® guaiac-based test (C1 from 2004 to 2006). METHODS:The participation rate of the eligible populati...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2020.101839
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:To present methodological issues that can arise with the assessment of the risk of a second primary cancer (SPC) occurring in the same site as a first cancer using registry data. MATERIAL AND METHODS:Data from ten French cancer registries were used, including data for patients with a first prostate cancer (i...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2017.10.004
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Infection is hypothesised as a contributory cause of childhood immune cell malignancies. Although some have reported associations between individual infections and immune cell malignancies, some could be spurious due to infections caused by malignancies that were already active prior to diagnosis. METHODS:I...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2020.101767
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Despite the progress made in recent years, multiple myeloma is still considered an incurable disease. Most survival data come from clinical trials. Little is known about the outcome in unselected real-life patients. METHODS:Overall survival was analyzed in a cohort of newly diagnosed symptomatic multiple my...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2015.08.002
更新日期:2015-10-01 00:00:00
abstract::Recent studies have identified the important role of cancer stem cells (CSCs) in carcinogenesis and relapse. However, with respect to multistage cancer metastasis, the role of CSCs has not been well-defined. In several human cancers, data showed that some phenotypic subsets of CSCs were responsible for cancer metastas...
journal_title:Cancer epidemiology
pub_type: 杂志文章,评审
doi:10.1016/j.canep.2012.07.007
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:We developed a novel method of methylation-specific PCR (MSP) using immunoprecipitation with anti-histone antibody (IP-MSP) to efficiently detect serum methylated DNA tightly bound to de-acetylated histones. MATERIALS AND METHODS:The detection limit of IP-MSP for p16 methylation was determined with a standa...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2010.01.004
更新日期:2010-04-01 00:00:00
abstract:OBJECTIVE:To investigate the clinical value in detecting occult primary tumors with (18)F-FDG PET-CT whole body imaging. METHODS:120 patients with unknown primary origin were referred for (18)F-FDG PET-CT whole body imaging. All patients were performed (18)F-FDG PET-CT whole body scan. PET-CT images were interpreted b...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2012.03.002
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:The aim of this study was to describe incidence patterns of lymphoid neoplasms in the Girona province (Spain) (1996-2015), and to predict the number of cases in Spain during 2020. METHODS:Data were extracted from the Girona cancer registry. Incident cases were classified using the ICD-O-3, third revision, a...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2018.11.001
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Peritoneal malignant mesothelioma is a rare disease for which few population-based studies are available. The aim of this study was to describe the evolution of the incidence and survival of peritoneal malignant mesothelioma in France between 1989 and 2015, using data derived from the French network of cance...
journal_title:Cancer epidemiology
pub_type: 历史文章,杂志文章
doi:10.1016/j.canep.2019.03.014
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Although the incidence of small intestinal adenocarcinoma (SIA) is low, rates are increasing and little information regarding modifiable lifestyle risk factors is available. AIM:To provide a systematic review of lifestyle factors and SIA risk. METHODS:Ovid MEDLINE, EMBASE and Web of science were searched f...
journal_title:Cancer epidemiology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.canep.2015.02.001
更新日期:2015-06-01 00:00:00
abstract:INTRODUCTION:The immunochemical fecal occult blood test (iFOBT) has been widely used for opportunistic colorectal cancer (CRC) screening in average-risk individuals seeking care from public health clinics in Malaysia. This study provides a 5-year outcome evaluation of such a practice. METHODS:The findings for a few ou...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2020.101829
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Androgen deprivation therapy (ADT) remains the mainstay treatment for locally advanced or metastatic prostate cancer (PC). However, potential effects of ADT treatment on neurocognitive dysfunction remain unclear. The present study was conducted to assess the relation between ADT treatment and risk of cogniti...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2019.101657
更新日期:2020-02-01 00:00:00
abstract:PURPOSE:We assessed the association between diabetes and breast cancer and whether physical activity modified the effect of diabetes on breast cancer in Hispanic women. METHODS:We used data from a case-control study of breast cancer among Hispanic women aged 30-79 conducted between 2003 and 2008 on the Texas-Mexico bo...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2010.06.001
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:While differences in CPM use between White and Black patients are well known, it is not clear whether CPM use differs by estrogen/progesterone receptor (ER/PR) status of tumors and whether racial/ethnic differences in the use are affected by ER/PR status, which varies between racial groups. The purpose of th...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2016.02.011
更新日期:2016-06-01 00:00:00
abstract:INTRODUCTION:This paper presents race-specific lung cancer mortality rates and the corresponding rate ratios for the 50 largest U.S. cities for the 5-year intervals 1990-1994 and 2005-2009. METHODS:The 50 largest cities in the U.S. were the units of analysis. Numerator data were abstracted from national death files wh...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2015.10.003
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:For myelodysplastic syndromes (MDS) (formerly known as preleukemia), a diverse group of myeloid neoplasms usually involving anemia in elderly persons, trends in U.S. death rates apparently have not been reported. METHODS:Trends in annual age-standardized rates per 100,000 from 1999 to 2009 were examined for...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2013.05.004
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:Cow's milk contain phytoestrogens especially equol depending on the composition of the feed ration. However, it is unknown whether milk differing in equol exhibits different estrogenicity in model systems and thereby potentially in humans as milk consumers. METHODS:The estrogenicity of high and low equol mi...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2009.04.003
更新日期:2009-07-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the contribution of the BRCA1 and BRCA2 promoter methylation in the pathogenesis of sporadic breast cancer in Tunisian patients. METHODS:Breast carcinoma tissues (n=117) and available paired normal breast tissues (n=65) from Tunisian women who had no family history were ...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2011.09.001
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:This article reports on the methods and framework we have developed to guide economic evaluation of noncommunicable disease registries. METHODS:We developed a cost data collection instrument, the Centers for Disease Control and Prevention's (CDC's) International Registry Costing Tool (IntRegCosting Tool), b...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2016.10.003
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Time to treatment of cancer is becoming a serious political and social issue. A greater understanding of the timeframes involved in cancer care is needed to reduce inequalities in access to care caused by delays. OBJECTIVE:To describe indicators of time to first treatment after colonoscopy in colon cancer (...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2015.10.002
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:The cancer research groups of the National Cancer Institute's National Clinical Trials Network have a history of successful conduct of large randomized phase III trials of chemoprevention for cancer. An important question for funding agencies is whether the conduct of large chemoprevention trials provides st...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2018.06.005
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Previous studies have shown that migrants have lower cancer mortality rates compared to the Australian-born population, particularly for colorectal and breast cancers, which are associated with an affluent lifestyle. This study seeks to update knowledge in this field by examining mortality from colorectal, s...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2011.10.011
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Ten genes are associated with increased susceptibility to inherited breast cancer have also been associated with population breast cancer risk, and all are involved directly or indirectly in the monoubiquitinated FANCD2-DNA damage repair pathway. We analyzed 13 haplotype blocks in eight of these genes to est...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2012.12.010
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Although, biologically plausible evidence has implicated coffee, tea and caffeine with carcinogenesis, there is a paucity of data on their associations with risk of cancer among Canadian women. Hence, we assessed their associations with risk of breast, endometrial and ovarian cancers within this population. ...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2018.07.013
更新日期:2018-10-01 00:00:00
abstract:AIM:Several studies indicate that use of hormone replacement therapy (HRT) is associated with an increased risk of intracranial meningioma, while associations between HRT use and risk of other brain tumors have been less explored. We investigated the influence of HRT use on the risk of glioma in a nationwide setting. ...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2013.09.017
更新日期:2013-12-01 00:00:00
abstract::Oral cancers are the 11th most common malignancy reported worldwide, accounting for 3% of all newly diagnosed cancer cases, and one with high mortality ratios among all malignancies. The objectives of this study were therefore to study the electrical properties of cancerous tongue tissue and normal tongue tissue, as w...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2009.12.017
更新日期:2010-04-01 00:00:00
abstract:AIM:We studied whether incidence of all cancer sites combined was associated with the radiation exposure due to fallout from the Chernobyl accident in Finland. An emphasis was on the first decade after the accident to assess the suggested "promotion effect". METHODS:The segment of Finnish population with a stable resi...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2013.05.006
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:Consumption of fruit and vegetables has been inversely related to gastric cancer. Two studies found that dietary antioxidant capacity has some role in explaining this association. We investigated the overall antioxidant effect from diet on gastric cancer using three measures of non-enzymatic antioxidant capa...
journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2015.04.003
更新日期:2015-06-01 00:00:00