Abstract：
PURPOSE:We assessed the association between diabetes and breast cancer and whether physical activity modified the effect of diabetes on breast cancer in Hispanic women. METHODS:We used data from a case-control study of breast cancer among Hispanic women aged 30-79 conducted between 2003 and 2008 on the Texas-Mexico border. In-person interviews were completed with 190 incident breast cancer cases ascertained through surgeons and oncologists, and 979 controls who were designated as both high-risk (n=511) and low-risk (N=468) for breast cancer (with respective response rates of 97%, 83% and 74%). RESULTS:After adjustment for menopausal status and mammography screening, there was no effect of diabetes on breast cancer risk (high-risk control group odds ratio [OR] 1.02, 95% confidence interval [CI] 0.71-1.48; low-risk control group OR 0.87, 0.58-1.30). Women who had a diabetes history and did not exercise were at no risk of breast cancer (OR 0.96, 95% CI 0.63-1.48) or a slightly reduced breast cancer risk (low-risk control group OR 0.72, 95% CI 0.46-1.15) depending on the control group used, while women with diabetes who did exercise had significantly reduced breast cancer risk (OR 0.41, 95% CI 0.21-0.83) regardless of the control group used (high-risk control group p-value for interaction=0.013, low-risk control group p-value for interaction 0.183). CONCLUSIONS:Should other studies confirm our results, physical activity should be explored as a means of reducing breast cancer risk in diabetic women.
journal_name
Cancer Epidemioljournal_title
Cancer epidemiologyauthors
Sanderson M,Peltz G,Perez A,Johnson M,Vernon SW,Fernandez ME,Fadden MKdoi
10.1016/j.canep.2010.06.001subject
Has Abstractpub_date
2010-10-01 00:00:00pages
556-61issue
5eissn
1877-7821issn
1877-783Xpii
S1877-7821(10)00107-4journal_volume
34pub_type
杂志文章abstract：BACKGROUND:Accumulated exposure to hormones and growth factors during early life may influence the future risk of breast cancer (BC). This study examines the influence of childhood-related, socio-demographic and anthropometric variables on BC risk, overall and by specific pathologic subtypes. METHODS:This is a case-co...
journal_title：Cancer epidemiology
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更新日期：2016-02-01 00:00:00
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pub_type： 杂志文章,多中心研究
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更新日期：2020-04-01 00:00:00
abstract：OBJECTIVES:This paper aims to determine whether racial disparities exist in hospitalization outcomes among African-American and White hospitalized prostate cancer patients in the United States. We evaluated racial differences among matched groups of patients in post-operative complications, hospital length of stay and ...
journal_title：Cancer epidemiology
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更新日期：2017-02-01 00:00:00
abstract：BACKGROUND:Uruguay, a country with one of the highest lung cancer rates worldwide, initiated a series of comprehensive anti-smoking measures in 2005. We assess the tobacco control policies in the context of cohort-driven lung cancer incidence trends over a 25-year period, providing baseline predictions to 2035. METHOD...
journal_title：Cancer epidemiology
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更新日期：2018-08-01 00:00:00
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abstract：BACKGROUND:The disparity in breast cancer mortality rates among white and black US women is widening, with higher mortality rates among black women. We apply functional time series models on age-specific breast cancer mortality rates for each group of women, and forecast their mortality curves using exponential smoothi...
journal_title：Cancer epidemiology
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abstract：OBJECTIVES:To compare the trends in prostate cancer incidence, treatment with curative intent and mortality across regions and counties in Norway, and to consider changes in incidence (an indicator for early diagnosis) and treatment with curative intent as explanatory factors for the decreasing prostate cancer mortalit...
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更新日期：2010-08-01 00:00:00
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journal_title：Cancer epidemiology
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更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:Global variations in the frequency of the major sub-types of lymphoma have been reported. However, studies on different sub-types of adult malignant lymphoma had never been conducted in Mashhad, Iran. In this paper, we aimed to identify the major sub-types of malignant lymphoma in our area and compare the di...
journal_title：Cancer epidemiology
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更新日期：2011-02-01 00:00:00
abstract：BACKGROUND:Polymorphisms in sex hormone receptor-encoding genes may alter the activity of sex hormone receptors and thereby affect susceptibility to breast cancer and related outcomes. METHODS:In a case-control study of women from Shanghai, China, we examined the risk of breast cancer and fibrocystic breast conditions...
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pub_type： 杂志文章,随机对照试验
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更新日期：2011-02-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2014-10-01 00:00:00
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pub_type： 历史文章,杂志文章
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更新日期：2019-06-01 00:00:00
abstract：INTRODUCTION:Antigenic stimulation is a proposed aetiologic mechanism for many haematological malignancies. Limited evidence suggests that community-acquired infections may increase the risk of acute myeloid leukaemia (AML) and myelodysplastic syndrome (MDS). However, associations with other myeloid malignancies includ...
journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2013.10.009
更新日期：2014-02-01 00:00:00
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journal_title：Cancer epidemiology
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abstract：BACKGROUND:Survival of children with cancer in resource-limited regions is very poor compared to better-resourced regions. Retinoblastoma (RB) is a childhood cancer that is commonly reported in many regions of Africa. RB may be safely and effectively treated by non-specialists, which could facilitate more widespread av...
journal_title：Cancer epidemiology
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journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2011.10.011
更新日期：2012-04-01 00:00:00
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更新日期：2019-08-01 00:00:00
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journal_title：Cancer epidemiology
pub_type： 杂志文章
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更新日期：2015-10-01 00:00:00
abstract：INTRODUCTION:This paper presents race-specific breast cancer mortality rates and the corresponding rate ratios for the 50 largest U.S. cities for each of the 5-year intervals between 2005 and 2014. METHODS:The 50 largest cities in the U.S. were the units of analysis. Numerator data were abstracted from national death ...
journal_title：Cancer epidemiology
pub_type： 杂志文章
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更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:Immigrant women often have lower cervical cancer screening (CCS) rates, tend to have a higher body mass index (BMI) and may be more vulnerable to BMI-related stigmatization. Our aim was to assess the role of BMI in differences in CCS rates by migration history. METHODS:Analyses were based on the 2012-2015 i...
journal_title：Cancer epidemiology
pub_type： 杂志文章
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更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:Barrett's Esophagus (BE), particularly long-segment Barrett's Esophagus, and the age of onset of Barrett's Esophagus are risk factors for esophageal adenocarcinoma. However, it is unknown if lifestyle factors such as alcohol abuse, tobacco use, weight gains that increase the risk of developing BE and esophag...
journal_title：Cancer epidemiology
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更新日期：2015-12-01 00:00:00
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journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2016.07.013
更新日期：2016-09-01 00:00:00
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更新日期：2013-06-01 00:00:00
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journal_title：Cancer epidemiology
pub_type： 杂志文章
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更新日期：2014-10-01 00:00:00
abstract：:Several risk factors for colorectal cancer (CRC) have been identified. If individuals with risk factors are more likely to harbor cancer or it precursors screening programs should be targeted toward this population. We evaluated the predictive value of colorectal cancer risk factors for the detection of advanced color...
journal_title：Cancer epidemiology
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更新日期：2013-06-01 00:00:00
