Abstract：
AIM:To review and summarize evidence from longitudinal studies on the association between serum 25-hydroxyvitamin D (25(OH)D) and the risk of prostate cancer (PC). METHODS:Relevant prospective cohort studies and nested case-control studies published until July 2009 were identified by systematically searching Ovid Medline, EMBASE, and ISI Web of Knowledge databases and by cross-referencing. The following data were extracted in a standardized manner from eligible studies: first author, publication year, country, study design, characteristics of the study population, duration of follow-up, PC incidence/PC mortality according to serum vitamin D status and the respective risk ratios, and covariates adjusted for in the analysis. Due to the heterogeneity of studies in categorizing serum vitamin D levels, all results were recalculated for an increase in serum 25(OH)D by 10ng/ml. Summary odds ratios (ORs) were calculated using meta-analysis methods. RESULTS:Overall, eleven original articles were included, ten of which reported on the association between serum vitamin D levels and PC incidence and one article reported on the association with PC mortality. Meta-analysis of studies on PC incidence resulted in a summary OR (95% confidence interval, CI) of 1.03 (0.96-1.11) associated with an increase of 25(OH)D by 10ng/ml (P=0.362). No indication for heterogeneity and publication bias was found. CONCLUSIONS:According to available evidence from longitudinal studies, serum 25(OH)D is not associated with PC incidence.
journal_name
Cancer Epidemioljournal_title
Cancer epidemiologyauthors
Yin L,Raum E,Haug U,Arndt V,Brenner Hdoi
10.1016/j.canep.2009.10.014subject
Has Abstractpub_date
2009-12-01 00:00:00pages
435-45issue
6eissn
1877-7821issn
1877-783Xpii
S1877-7821(09)00143-Xjournal_volume
33pub_type
杂志文章,meta分析abstract：BACKGROUND:Telomeres help maintain chromosomal structure and may influence tumorigenesis. We examined the association between telomere length and skin cancer in a clinic-based case-control study of 198 melanoma cases, 136 squamous cell carcinoma (SCC) cases, 185 basal cell carcinoma (BCC) cases, and 372 healthy control...
journal_title：Cancer epidemiology
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更新日期：2013-08-01 00:00:00
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journal_title：Cancer epidemiology
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abstract：:Recent studies have identified the important role of cancer stem cells (CSCs) in carcinogenesis and relapse. However, with respect to multistage cancer metastasis, the role of CSCs has not been well-defined. In several human cancers, data showed that some phenotypic subsets of CSCs were responsible for cancer metastas...
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pub_type： 杂志文章,评审
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abstract：INTRODUCTION:The immunochemical fecal occult blood test (iFOBT) has been widely used for opportunistic colorectal cancer (CRC) screening in average-risk individuals seeking care from public health clinics in Malaysia. This study provides a 5-year outcome evaluation of such a practice. METHODS:The findings for a few ou...
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journal_title：Cancer epidemiology
pub_type： 杂志文章,评审
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pub_type： 杂志文章
doi：10.1016/j.canep.2020.101827
更新日期：2020-12-01 00:00:00
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journal_title：Cancer epidemiology
pub_type： 杂志文章,评审
doi：10.1016/j.canep.2009.10.009
更新日期：2009-11-01 00:00:00
abstract：:The three times higher incidence of thyroid cancer in women compared to men points to a role of female sex hormones in its etiology. However the effects of these factors are poorly understood. We analyzed the association between thyroid cancer and hormonal and reproductive factors among women enrolled in CATHY, a popu...
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pub_type： 杂志文章
doi：10.1016/j.canep.2017.04.001
更新日期：2017-06-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.canep.2020.101851
更新日期：2020-12-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.canep.2015.04.003
更新日期：2015-06-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.canep.2020.101839
更新日期：2020-12-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.canep.2013.05.006
更新日期：2013-10-01 00:00:00
abstract：BACKGROUND:Although, biologically plausible evidence has implicated coffee, tea and caffeine with carcinogenesis, there is a paucity of data on their associations with risk of cancer among Canadian women. Hence, we assessed their associations with risk of breast, endometrial and ovarian cancers within this population. ...
journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2018.07.013
更新日期：2018-10-01 00:00:00
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pub_type： 杂志文章
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更新日期：2018-12-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.canep.2014.07.011
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pub_type： 杂志文章
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更新日期：2019-02-01 00:00:00
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pub_type： 杂志文章,多中心研究
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更新日期：2011-04-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.canep.2018.11.010
更新日期：2019-02-01 00:00:00
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pub_type： 杂志文章
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更新日期：2017-06-01 00:00:00
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journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2019.101566
更新日期：2019-10-01 00:00:00
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journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2011.07.006
更新日期：2012-06-01 00:00:00
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journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2012.12.002
更新日期：2013-04-01 00:00:00
abstract：BACKGROUND:Individuals with Neurofibromatosis Type 1 (NF1) are strongly predisposed to developing pediatric brain tumors (PBTs), especially optic pathway gliomas (OPGs). Although developmental factors have been implicated in the origins of PBTs in both human and animal studies, associations between early-life factors a...
journal_title：Cancer epidemiology
pub_type： 杂志文章
doi：10.1016/j.canep.2016.03.005
更新日期：2016-06-01 00:00:00
