Abstract:
BACKGROUND:There is a strong evidence for a protective role of physical activity (PA) on cancers of the colon, breast (postmenopausal) and endometrium, but data are less consistent or scarce for other cancer types. This study assessed the relationship between occupational and recreational PA and cancer risk among men in a population-based case-control study conducted in Montreal, Canada. METHODS:Incident cases of cancer of the lung (n=857), colon (n=496), bladder (n=484), prostate (n=449), stomach (n=251), rectum (n=248), non-Hodgkin's lymphoma (n=215), kidney (n=177), pancreas (n=116), melanoma (n=103), esophagus (n=99), Hodgkin's lymphoma (n=54), and 533 population controls, were interviewed. Detailed lifetime occupational PAs were translated into metabolic equivalents. Participation in sports and outdoor activities was elicited. RESULTS:Compared to those with low lifetime occupational PA levels, men with high occupational PA levels had decreased odds ratios (OR) for all cancer types. The strongest evidence was for cancers of the colon [OR: 0.58, 95% confidence interval (CI): 0.34-0.99] and the prostate (OR: 0.54, 95% CI: 0.31-0.95). Men engaging in sports and outdoor activities had lower risks of lung (OR: 0.69, 95% CI: 0.52-0.91), esophageal (OR: 0.54, 95% CI: 0.30-0.97) and bladder (OR: 0.78, 95% CI: 0.59-1.05) cancers, and somewhat increased risks of melanoma (OR: 1.24, 95% CI: 0.73-2.12). CONCLUSIONS:A protective effect of high lifetime occupational PA levels was observed for colon and prostate cancers. A tendency for inverse associations was also noted for several other cancer types. Recreational PA was inversely related with smoking-related cancers including lung, esophageal and bladder cancers.
journal_name
Cancer Epidemioljournal_title
Cancer epidemiologyauthors
Parent MÉ,Rousseau MC,El-Zein M,Latreille B,Désy M,Siemiatycki Jdoi
10.1016/j.canep.2010.09.004subject
Has Abstractpub_date
2011-04-01 00:00:00pages
151-9issue
2eissn
1877-7821issn
1877-783Xpii
S1877-7821(10)00164-5journal_volume
35pub_type
杂志文章,多中心研究abstract:BACKGROUND:The cancer research groups of the National Cancer Institute's National Clinical Trials Network have a history of successful conduct of large randomized phase III trials of chemoprevention for cancer. An important question for funding agencies is whether the conduct of large chemoprevention trials provides st...
journal_title:Cancer epidemiology
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journal_title:Cancer epidemiology
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abstract::Tobacco smoking continues to be the leading preventable cause of morbidity and mortality worldwide. Each year more than 5 million smokers die prematurely because of their habit wreaking havoc on the welfare of families and communities worldwide. While cigarettes remain the main tobacco killer worldwide, for many youth...
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pub_type: 杂志文章,评审
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2014.10.012
更新日期:2015-02-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.canep.2019.02.008
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journal_title:Cancer epidemiology
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更新日期:2016-06-01 00:00:00
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pub_type: 历史文章,杂志文章
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更新日期:2020-12-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2013.05.002
更新日期:2013-10-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.canep.2015.10.002
更新日期:2015-12-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2017.12.006
更新日期:2018-02-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2016.12.001
更新日期:2017-02-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.canep.2018.06.004
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journal_title:Cancer epidemiology
pub_type: 杂志文章,meta分析,评审
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2013.03.006
更新日期:2013-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-10-01 00:00:00
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pub_type: 杂志文章
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更新日期:2019-12-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2009.04.003
更新日期:2009-07-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章,多中心研究
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更新日期:2010-10-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2016.12.007
更新日期:2017-02-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2011.10.004
更新日期:2012-06-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2012.03.002
更新日期:2012-10-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章,评审
doi:10.1016/j.canep.2009.10.009
更新日期:2009-11-01 00:00:00
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journal_title:Cancer epidemiology
pub_type: 杂志文章
doi:10.1016/j.canep.2011.07.007
更新日期:2011-12-01 00:00:00