Alternative NADH dehydrogenase (NDH2): intermembrane-space-facing counterpart of mitochondrial complex I in the procyclic Trypanosoma brucei.

abstract：:A recombinant baculovirus-expressed hybrid protein containing epitopes for the C-terminal fragment of the Plasmodium falciparum precursor to the major merozoite surface antigens (PMMSA) and the tetrapeptide repeats of the circumsporozoite protein (CSP) was assessed for its immunogenicity. Murine MHC-II restriction of ...

journal_title：Parasitology

authors： Lockyer MJ,Cooper H,Tite J,Rowan W,Crowe JS

更新日期：1993-06-01 00:00:00

abstract：:The complete sequence of the 18S small subunit (SSU) ribosomal DNA of Hammondia hammondi and Sarcocystis mucosa was obtained and compared to SSU rDNA sequences of Neospora caninum, Toxoplasma gondii, Besnoitia besnoiti, 2 species of Frenkelia, 3 species of Isospora, and 13 species of Sarcocystis. Analyses showed that ...

journal_title：Parasitology

authors： Jenkins MC,Ellis JT,Liddell S,Ryce C,Munday BL,Morrison DA,Dubey JP

更新日期：1999-08-01 00:00:00

abstract：:This paper investigates a cohort of 2187 laboratory reared Culex quinquefasciatus fed on 69 human volunteers, including 59 persons with different levels of Wuchereria bancrofti microfilariae and 10 without microfilaria. Mosquitoes were followed until death. Mosquito survival was analysed in relation to the level of mi...

journal_title：Parasitology

authors： Krishnamoorthy K,Subramanian S,Van Oortmarssen GJ,Habbema JD,Das PK

更新日期：2004-07-01 00:00:00

abstract：:The kinetoplastid parasite Trypanosoma brucei causes African trypanosomiasis in both humans and animals. Infections place a significant health and economic burden on developing nations in sub-Saharan Africa, but few effective anti-parasitic treatments are currently available. Hence, there is an urgent need to identify...

journal_title：Parasitology

authors： Dickie EA,Young SA,Smith TK

更新日期：2019-04-01 00:00:00

abstract：:In light of the low success rate of target-based genomics and HTS (High Throughput Screening) approaches in anti-infective drug discovery, in silico structure-based drug design (SBDD) is becoming increasingly prominent at the forefront of drug discovery. In silico SBDD can be used to identify novel enzyme inhibitors r...

journal_title：Parasitology

authors： Cunningham F,McPhillie MJ,Johnson AP,Fishwick CW

更新日期：2014-01-01 00:00:00

abstract：:To test the homogeneity of 18S sequences within Trypanosoma cruzi, riboprint profiles were separated by temperature gradient gel electrophoresis (TGGE). Upon interpretation of melting curves of fragments within a riboprint profile, there appeared to be two 18S sequence types within each stock examined. Two similar typ...

journal_title：Parasitology

authors： Stothard JR,Frame IA,Carrasco HJ,Miles MA

更新日期：1998-09-01 00:00:00

abstract：:Intraerythrocytic malaria parasites ingest the cytosol of their host cell and digest it inside their acid food vacuoles. Acidified (pH 4-5.5, 37 degrees C) human red blood cell lysates were used to simulate this process, measuring the denaturation of haemoglobin (Hb) and the release of iron, in the absence or presence...

journal_title：Parasitology

authors： Gabay T,Krugliak M,Shalmiev G,Ginsburg H

更新日期：1994-05-01 00:00:00

abstract：:The glycogen stores of adult Schistosoma mansoni worms could be labelled by incubation of the worms, after an initial reduction of their glycogen content, in the presence of [6-14C]glucose. Subsequent breakdown of the labelled glycogen by the parasite revealed that glycogen was degraded to lactate and carbon dioxide. ...

journal_title：Parasitology

authors： Tielens AG,Celik C,Van den Heuvel JM,Elfring RH,Van den Bergh SG

更新日期：1989-02-01 00:00:00

abstract：:The statistical aggregation of parasites among hosts is often described empirically by the negative binomial (Poisson-gamma) distribution. Alternatively, the Poisson-lognormal model can be used. This has the advantage that it can be fitted as a generalized linear mixed model, thereby quantifying the sources of aggrega...

journal_title：Parasitology

authors： Elston DA,Moss R,Boulinier T,Arrowsmith C,Lambin X

更新日期：2001-05-01 00:00:00

abstract：:To assess the prevalence of Taenia solium cysticercosis in patients with neurological disorders in Slovenia, serum/cerebrospinal fluid (CSF) samples from 348 suspected patients were collected between the beginning of January 2001 and the end of December 2012 and analysed serologically for the presence of anti-T. soliu...

journal_title：Parasitology

authors： Šoba B,Beović B,Lužnik Z,Skvarč M,Logar J

更新日期：2014-04-01 00:00:00

abstract：:Avian malaria is a mosquito-borne disease caused by Plasmodium spp. protozoa. Although these parasites have been extensively studied in North America and Eurasia, knowledge on the diversity of Plasmodium, its vectors and avian hosts in Africa is scarce. In this study, we report on natural malarial infections in free-r...

journal_title：Parasitology

authors： Aly MZY,Mohamed III,Sebak SI,Vanstreels RET,El Gendy AM

更新日期：2020-08-01 00:00:00

abstract：:As has been shown previously, immunologically intact mice with patent Schistosoma mansoni infections had a significantly lower mean platelet number than intact uninfected mice (P<0.0001). However, platelet numbers in T-cell deprived mice with patent infections were not significantly different from those in uninfected ...

journal_title：Parasitology

authors： Stanley RG,Ngaiza JR,Atieno E,Jell G,Francklow K,Jackson CL,Parry H,Doenhoff MJ

更新日期：2003-03-01 00:00:00

abstract：:Sex ratio theory posits that the adaptive proportion of male to female gametocytes of a malaria parasite within the vertebrate host depends on the degree of inbreeding within the vector. Gametocyte sex ratio could be phenotypically flexible, being altered based on the infection's clonal diversity, and thus likely inbr...

journal_title：Parasitology

authors： Osgood SM,Schall JJ

更新日期：2004-01-01 00:00:00

abstract：:A guinea-pig immunoglobulin-G linked agarose column was used to detect the immunoglobulin-G binding proteins (IGBP) in the ixodid ticks, Rhipicephalus appendiculatus, Amblyomma variegatum and Ixodes hexagonus. IGBPs were found in salivary gland extract (SGE) of the unfed ticks of all 3 species. The sizes of the IGBPs,...

journal_title：Parasitology

authors： Wang H,Nuttall PA

更新日期：1995-08-01 00:00:00

abstract：:Depending on the extent of evolutionary divergence among parent taxa, hybrids may suffer from a breakdown of co-adapted genes or may conversely exhibit vigour due to the heterosis effect, which confers advantages to increased genetic diversity. That last mechanism could explain the success of hybrids when hybridizatio...

journal_title：Parasitology

authors： Planade B,Lena JP,Li H,Plenet S,Guegan JF,Thomas F,Hurtrez-Bousses S,Renaud F,Joly P

更新日期：2009-08-01 00:00:00

abstract：:Despite the great interest to quantify the structure of host-parasite interaction networks, the real influence of some factors such as taxonomy, host body size and ecological opportunity remains poorly understood. In this paper, we investigate the general patterns of organization and structure of interactions in two a...

journal_title：Parasitology

authors： D'Bastiani E,Campião KM,Boeger WA,Araújo SBL

更新日期：2020-11-01 00:00:00

abstract：:Intact, viable adults, infective and newborn larvae of Trichinella pseudospiralis were surface labelled with 125I by the chloramine T method and labelled proteins were compared with those obtained from equivalent stages of T. spiralis. Electron-microscope autoradiography determined that labelled proteins were restrict...

journal_title：Parasitology

authors： Almond NM,McLaren DJ,Parkhouse RM

更新日期：1986-08-01 00:00:00

abstract：:Most of our knowledge about the process of penetration of skin, by cercariae of Schistosoma mansoni, has been gained from studies carried out in vivo with laboratory animals. Human skin is significantly different from that of other animals but there are obvious practical difficulties in directly studying attachment an...

journal_title：Parasitology

authors： Khammo N,Bartlett A,Clothier RH,Whitfield PJ

更新日期：2002-01-01 00:00:00

abstract：:Vertically transmitted parasites (VTPs) such as Wolbachia are expected not only to minimize the damage they inflict on their hosts, but also to protect their hosts against the damaging effects of coinfecting parasites. By modifying the fitness costs of the infection, VTPs can therefore play an important role in the ev...

journal_title：Parasitology

authors： Zélé F,Denoyelle J,Duron O,Rivero A

更新日期：2018-05-01 00:00:00

abstract：:Leishmania braziliensis strain M2903 was adapted for growth and serially maintained as amastigotes at 34 degrees C in modified UM-54 medium, with growth curves exhibiting typical log and stationary phases. In late passages, amastigote growth took place in the absence of supplementary haemin and was unaffected when the...

journal_title：Parasitology

authors： Balanco JM,Pral EM,da Silva S,Bijovsky AT,Mortara RA,Alfieri SC

更新日期：1998-02-01 00:00:00

abstract：:The sequence of appearance of specific lytic activity against more than 20 variable antigen types (VATs) of Trypanosoma vivax in the serum of 27 animals belonging to 5 species has been examined. For each host species there was a characteristic course of infection, with differences in height and duration of parasitaemi...

journal_title：Parasitology

authors： Barry JD

更新日期：1986-02-01 00:00:00

abstract：:Studies of the kinetics of adenosine transport were carried out on the P1 and P2 transporters of drug-sensitive Trypanosoma evansi and its cloned derivative, resistant to the melaminophenyl arsenical Mel CY. Characterization of adenosine uptake was made by estimation of the maximum concentration taken up at time infin...

journal_title：Parasitology

authors： Suswam EA,Ross CA,Martin RJ

更新日期：2003-12-01 00:00:00

abstract：:The complex life-cycles of parasitic animals are a product of exploiting the process of development to generate organisms with different biological potentials within a species. Successive stages of the parasite adapt to functions such as host invasion and transmission, and to the colonization of a variety of niches, o...

journal_title：Parasitology

authors： Bianco AE,Maizels RM

更新日期：1989-01-01 00:00:00

abstract：:Traditionally, the family Campulidae has been associated either with the family Fasciolidae, parasites of ruminants, or the Acanthocolpidae, parasites of fishes, based on morphological similarities. Since morphology does not seem to resolve clearly the problem of the relationships of campulids, we have used the sequen...

journal_title：Parasitology

authors： Fernandez M,Littlewood DT,Latorre A,Raga JA,Rollinson D

更新日期：1998-10-01 00:00:00

abstract：:A multi-subunit antigen (native M(r) > 200 kDa, reduced M(r) 97-100 kDa) has been identified in homogenates of Trichinella spiralis larvae using affinity-purified rabbit anti-keyhole limpet haemocyanin (KLH) antibodies and its cross-reactivity with KLH was confirmed by competition blotting. The antigen was not present...

journal_title：Parasitology

authors： Modha J,Robertson WM,Kennedy MW,Kusel JR

更新日期：1994-11-01 00:00:00

abstract：:Amoebiasis, infection by the protozoan parasite Entamoeba histolytica, remains a global health problem, despite the availability of effective treatment. While improved sanitation could lead to the eradication of this disease, it is unlikely that this will occur worldwide in the foreseeable future; thus alternative mea...

journal_title：Parasitology

authors： Stanley SL Jr

更新日期：2006-01-01 00:00:00

abstract：:Ticks are of vast medical and veterinary public health importance due to direct damage caused by feeding and their roles in transmitting well known and emerging infectious agents. Ticks and tick-borne pathogens stimulate the immune system of the host. Those immune interactions are of importance in tick biology, pathog...

journal_title：Parasitology

authors： Brossard M,Wikel SK

更新日期：2004-01-01 00:00:00

abstract：:Giardia lamblia localize and multiply in the small intestine and may cause acute or chronic diarrhoea with malabsorption of fat, protein and other nutrients. Abnormal pancreatic function has been documented in giardiasis and trophozoites directly inhibit pancreatic lipase activity in vitro. The aim of this study was t...

journal_title：Parasitology

authors： Seow F,Katelaris P,Ngu M

更新日期：1993-04-01 00:00:00

abstract：:The development of microgamonts was studied in the small intestine of a 2-day-old cat after oral inoculation with 10(7) bradyzoites of Sarcocystis hirsuta. The cat was given bradyzoites in 2 doses at 2 h apart and killed 4 h later. Gamonts were seen in parasitophorous vacuoles of goblet cells in the epithelium of the ...

journal_title：Parasitology

authors： Dubey JP

更新日期：1983-02-01 00:00:00

abstract：:Many marine fisheries in South American Atlantic coasts (SAAC) are threatened by overfishing and under serious risk of collapsing. The SAAC comprises a diversity of environments, possesses a complex oceanography and harbours a vast biodiversity that provide an enormous potential for using parasites as biological tags ...

journal_title：Parasitology

authors： Cantatore DM,Timi JT

更新日期：2015-01-01 00:00:00