Changes in adenosine transport associated with melaminophenyl arsenical (Mel CY) resistance in Trypanosoma evansi: down-regulation and affinity changes of the P2 transporter.

abstract：:Host-parasite interactions are shaped by the co-evolutionary arms race of parasite virulence, transmission success as well as host resistance and recovery. The virulence and fitness of parasites may depend on host condition, which is mediated, for instance, by host energy constraints. Here, we investigated to what ext...

journal_title：Parasitology

authors： Coors A,De Meester L

更新日期：2011-01-01 00:00:00

abstract：:We examined the mechanism of action and compared the anthelmintic efficacy of cysteine proteinases from papaya, pineapple, fig, kiwi fruit and Egyptian milkweed in vitro using the rodent gastrointestinal nematode Heligmosomoides polygyrus. Within a 2 h incubation period, all the cysteine proteinases, with the exceptio...

journal_title：Parasitology

authors： Stepek G,Buttle DJ,Duce IR,Lowe A,Behnke JM

更新日期：2005-02-01 00:00:00

abstract：:The population of malaria-causing parasites is characterized by great genetic diversity. Knowledge of the polymorphism generation mechanism is a central issue for developing effective vaccines against malaria and understanding the parasite population structure. Plasmodium vivax genetic diversity has been explained in ...

journal_title：Parasitology

authors： Martinez P,Suarez CF,Cardenas PP,Patarroyo MA

更新日期：2004-04-01 00:00:00

abstract：:A cDNA clone codifying ribosomal protein L25 was isolated from a Leishmania braziliensis cDNA gene library. The alignment of the amino acid sequence deduced from this gene with other proteins revealed that this protein is related to the L23/25 rihosomal protein family. This is so because this protein shows, in its C-t...

journal_title：Parasitology

authors： González AC,Martínez E,Carmelo E,Piñero JE,Alonso V,Del Castillo A,Valladares B

更新日期：2002-07-01 00:00:00

abstract：:Acetylcholinesterase (AChE) is present in all stages of the life-cycle of schistosomes and is located in muscle and on the surface of the parasite. Metrifonate is a drug that inhibits AChE. We compared the AChEs from three schistosome species (Schistosoma mansoni, Schistosoma haematobium and Schistosoma bovis) that ha...

journal_title：Parasitology

authors： Camacho M,Tarrab-Hazdai R,Espinoza B,Arnon R,Agnew A

更新日期：1994-02-01 00:00:00

abstract：:Glucose uptake was examined in adult specimens of Proterometra macrostoma (Trematoda: Digenea) recovered from the stomach (endoparasites) and gills (ectoparasites) of longear sunfish, Lepomis megalotis. The endoparasitic forms transported glucose directly through the external body surface by Na+-independent, facilitat...

journal_title：Parasitology

authors： Uglem GL

更新日期：1987-02-01 00:00:00

abstract：:Neurological involvement following trypanosome infection has been recognised for over a century. However, there are still many unanswered questions concerning the mechanisms used by the parasite to gain entry to the CNS and the pathogenesis of the resulting neuroinflammatory reaction. There is a paucity of material fr...

journal_title：Parasitology

authors： Rodgers J

更新日期：2010-12-01 00:00:00

abstract：:Post-mesocyclic development of Trypanosoma brucei in the tsetse fly in its migration from midgut to salivary glands, was revisited by sequential microdissection, morphometry and DNA-cytofluorometry. This development started by day 6 after the infective feed, with passage of mesocyclic midgut trypomastigotes through pr...

journal_title：Parasitology

authors： Van Den Abbeele J,Claes Y,van Bockstaele D,Le Ray D,Coosemans M

更新日期：1999-05-01 00:00:00

abstract：:The presence of introduced hosts can increase or decrease infections of co-introduced parasites in native species of conservation concern. In this study, we compared parasite abundance, intensity, and prevalence between native Awaous stamineus and introduced poeciliid fishes by a co-introduced nematode parasite (Camal...

journal_title：Parasitology

authors： Gagne RB,Heins DC,McIntyre PB,Gilliam JF,Blum MJ

更新日期：2016-10-01 00:00:00

abstract：:Electrophoresis of secretions collected from Globodera pallida revealed a smeared region between 25 and 50 kDa, and a single band of < 20 kDa. The secretions were used to raise an antiserum (LW1). Immunoblotting of parasite homogenates with LW1 differentiated G. pallida from its sibling species G. rostochiensis and re...

journal_title：Parasitology

authors： Duncan LH,Robertson L,Robertson WM,Kusel JR

更新日期：1997-10-01 00:00:00

abstract：:Trypanosoma cruzi, causative agent of Chagas disease, co-infects its triatomine vector with its sister species Trypanosoma rangeli, which shares 60% of its antigens with T. cruzi. Additionally, T. rangeli has been observed to be pathogenic in some of its vector species. Although T. cruzi-T. rangeli co-infections are c...

journal_title：Parasitology

authors： Peterson JK,Graham AL,Elliott RJ,Dobson AP,Triana Chávez O

更新日期：2016-08-01 00:00:00

abstract：:The nematode-trapping fungus Arthrobotrys oligospora traps and invades all the free-living juvenile stages of the trichostrongyle nematode Trichostrongylus colubriformis. The processes of capture and invasion of the 1st-stage juveniles are described using differential interference contrast optics and 3-D reconstructio...

journal_title：Parasitology

authors： Murray DS,Wharton DA

更新日期：1990-08-01 00:00:00

abstract：:Although the rumen fluke, Calicophoron daubneyi is now very common and widespread throughout Western Europe, reports of clinical cases are still rare. This study explores the epidemiological background to a severe rumen fluke outbreak in 6-month-old heifers on a dairy farm in Ireland. Sequence analysis of the cytochro...

journal_title：Parasitology

authors： O'Shaughnessy J,Garcia-Campos A,McAloon CG,Fagan S,de Waal T,McElroy M,Casey M,Good B,Mulcahy G,Fagan J,Murphy D,Zintl A

更新日期：2018-06-01 00:00:00

abstract：:The current World Health Organization strategic plan targets the elimination of schistosomiasis as a public health problem by 2025 and accurate diagnostics will play a pivotal role in achieving this goal. DNA-based detection methods provide a viable alternative to some of the commonly used tests, notably microscopy an...

journal_title：Parasitology

authors： Weerakoon KG,Gordon CA,Cai P,Gobert GN,Duke M,Williams GM,McManus DP

更新日期：2017-07-01 00:00:00

abstract：:The accumulation of the trypanocide isometamidium chloride (Samorin, RMB Animal Health Ltd., UK) by a range of clones of Trypanosoma congolense with varying sensitivity to the drug, was measured by methods based on the fluorescence of isometamidium. Fluorescence microscopy and flow cytometry showed a reduction in drug...

journal_title：Parasitology

authors： Sutherland IA,Peregrine AS,Lonsdale-Eccles JD,Holmes PH

更新日期：1991-10-01 00:00:00

abstract：:Infection of intermediate hosts with eggs of taeniid parasites results in a larval infestation known as cysticercosis. A number of studies have indicated that cysticercosis is associated with immunosuppression, although little is known about the mechanisms involved. In the present study, mice infected with the larvae ...

journal_title：Parasitology

authors： Villa OF,Kuhn RE

更新日期：1996-06-01 00:00:00

abstract：:We tested whether the prevalence of ticks can be predicted reliably from a simple epidemiological model that takes into account only mean abundance and its variance. We used data on the abundance and distribution of larvae and nymphs of 2 ixodid ticks parasitic on small mammals (Apodemus agrarius, Apodemus flavicollis...

journal_title：Parasitology

authors： Stanko M,Krasnov BR,Miklisova D,Morand S

更新日期：2007-01-01 00:00:00

abstract：:Human strongyloidiasis is a serious disease mostly attributable to Strongyloides stercoralis and to a lesser extent Strongyloides fuelleborni, a parasite mainly of non-human primates. The role of animals as reservoirs of human-infecting Strongyloides is ill-defined, and whether dogs are a source of human infection is ...

journal_title：Parasitology

authors： Barratt JLN,Sapp SGH

更新日期：2020-09-01 00:00:00

abstract：:A large database on the transmission of a stabilate of the Theileria parva Muguga stock from one breed of cattle using two stocks of Rhipicephalus appendiculatus, Muguga and Ol Pejeta was developed and analysed. Factors associated with the ticks and cattle, and the infections developing in cattle were studied in relat...

journal_title：Parasitology

authors： Young AS,Dolan TT,Morzaria SP,Mwakima FN,Norval RA,Scott J,Sherriff A,Gettinby G

更新日期：1996-09-01 00:00:00

abstract：:The number of facilities in which customers make contact with cats before eating and drinking, called 'cat cafés', has recently increased in Tokyo, Japan. In a survey to clarify the possibility of zoonotic transmission in Giardia duodenalis, the infection rates of G. duodenalis in 321 stool samples of cats from 16 cat...

journal_title：Parasitology

authors： Suzuki J,Murata R,Kobayashi S,Sadamasu K,Kai A,Takeuchi T

更新日期：2011-04-01 00:00:00

abstract：:In Strongyloides ratti-infected rats, 2 peaks of egg excretion were observed; a large one with maximum egg production on days 7-8 of infection and a small more inconspicuous one around day 25. The second peak, which had been ignored in most studies, was produced by adults in the caecum and the colon. The adults were l...

journal_title：Parasitology

authors： Kimura E,Shintoku Y,Kadosaka T,Fujiwara M,Kondo S,Itoh M

更新日期：1999-08-01 00:00:00

abstract：:Cryptosporidia are important protozoan parasites of vertebrates, and a number of species and genotypes, with different host ranges, have been described. In this study a protocol was established for the detection and the genetic characterization of Cryptosporidium spp. isolated from various types of surface waters (riv...

journal_title：Parasitology

authors： Ward PI,Deplazes P,Regli W,Rinder H,Mathis A

更新日期：2002-04-01 00:00:00

abstract：:Parasites can have a wide range of pathophysiological effects on the host. This review describes those associated with some parasites of major importance in man and animals. Haemoprotozoan diseases such as trypanosomiasis and malaria are primarily associated with anaemia. Such anaemias have a complex aetiology involvi...

journal_title：Parasitology

authors： Holmes PH

更新日期：1987-01-01 00:00:00

abstract：:Chagas infection is a major endemic disease affecting Latin American countries. The persistence of Trypanosoma cruzi generates a chronic inflammatory reactivity that induces an immune response directed to the host's tissues. The effectiveness of the treatment in the chronic phase is still unsatisfactory due, amongst o...

journal_title：Parasitology

authors： Fauro R,Lo Presti S,Bazan C,Baez A,Strauss M,Triquell F,Cremonezzi D,Negrete OS,Willhuber GC,Paglini-Oliva P,Rivarola HW

更新日期：2013-06-01 00:00:00

abstract：:In situations where malaria eradication is not an option in the foreseeable future the emphasis must be on the control of morbidity and mortality due to malaria. Under such circumstances drawing a distinction between malarial parasitization and malarial disease may be important for workers in both field and laboratory...

journal_title：Parasitology

authors： Marsh K

更新日期：1992-01-01 00:00:00

abstract：:Heparin-binding proteins (HBPs) play a key role in Trypanosoma cruzi-host cell interactions. HBPs recognize heparan sulfate (HS) at the host cell surface and are able to induce the cytoadherence and invasion of this parasite. Herein, we analysed the biochemical properties of the HBPs and also evaluated the expression ...

journal_title：Parasitology

authors： Oliveira FO Jr,Alves CR,Silva FS,Côrtes LM,Toma L,Bouças RI,Aguilar T,Nader HB,Pereira MC

更新日期：2013-02-01 00:00:00

abstract：:Recombinant ribosomal DNA sequences were amplified by PCR and used as probes to perform a fingerprint analysis of total DNA from different Entamoeba histolytica isolates. RFLPs obtained with one of the probes, R-1, support previous proposals that pathogenic and non-pathogenic E. histolytica are closely related, yet ge...

journal_title：Parasitology

authors： Cruz-Reyes JA,Spice WM,Rehman T,Gisborne E,Ackers JP

更新日期：1992-04-01 00:00:00

abstract：:We have cloned a cDNA encoding a novel antigen from a Sarcoptes scabiei (Acari) cDNA library by immunoscreening with sera from S. scabiei-infected dogs. The antigen is encoded by a 2,157 bp mRNA with a predicted open reading frame of 719 amino acids (molecular weight 79 kDa). Our sequence analysis identified the prese...

journal_title：Parasitology

authors： Ljunggren EL,Bergström K,Morrison DA,Mattsson JG

更新日期：2006-01-01 00:00:00

abstract：SUMMARY:The spermatozoa of ticks are anomalous in many respects: they are very large, cytoplasm-rich cells which lack a flagellum but move with a peculiar gliding motility. Their metamorphosis after deposition in the female has been well documented, but many of the subsequent events in the career of the spermatozoa are...

journal_title：Parasitology

authors： Resler JH,Frazier JL,Shepherd JG,Modafferi JD

更新日期：2009-04-01 00:00:00

abstract：:The Calliphoridae include some of the most economically significant myiasis-causing flies in the world - blowflies and screwworm flies - with many being notorious for their parasitism of livestock. However, despite more than 50 years of research, key taxonomic relationships within the family remain unresolved. This st...

journal_title：Parasitology

authors： McDonagh LM,Stevens JR

更新日期：2011-11-01 00:00:00