Use of clomipramine as chemotherapy of the chronic phase of Chagas disease.

abstract：:The importance of host heterogeneity in generating aggregation was investigated using Heligmosomoides polygyrus (Nematoda) in laboratory mice. Parameters of infection were compared between inbred and outbred mice, between primary and challenge infection protocols, and between gavage and natural exposure protocols, to ...

journal_title：Parasitology

authors： Tanguay GV,Scott ME

更新日期：1992-06-01 00:00:00

abstract：:Freshwater snails of the Bulinus forskalii group are one of four Bulinus species complexes responsible for the transmission of schistosomes in Africa and adjacent regions. The species status of these conchologically variable and widely distributed planorbids remains unclear, and parasite compatibility varies considera...

journal_title：Parasitology

authors： Jones CS,Rollinson D,Mimpfoundi R,Ouma J,Kariuki HC,Noble LR

更新日期：2001-01-01 00:00:00

abstract：:A number of authors have demonstrated that the schistosomicidal compound, Praziquantel (Pzq), depends for its action upon the immune status of the host (Sabah et al. 1985; Brindley & Sher, 1987; Doenhoff et al. 1987). We have attempted to define the synergistic interaction between immuno- and chemotherapy further, usi...

journal_title：Parasitology

authors： Piper KP,Mott RF,Hockley DJ,McLaren DJ

更新日期：1991-10-01 00:00:00

abstract：:Perkinsus marinus is a protozoan responsible for dramatic mortality in the Eastern oyster, Crassostrea virginica, but not in the Pacific oyster, C. gigas. To understand the host-parasite relationship, we inoculated P. marinus trophozoites into the shell cavity of C. gigas and measured, over 2 months, (i) intensity of ...

journal_title：Parasitology

authors： Romestand B,Corbier F,Roch P

更新日期：2002-10-01 00:00:00

abstract：:Increased permeability of capillaries and venules, labelled with colloidal carbon, was observed in the superficial mucosa of the small intestine of sheep infected with Trichostrongylus colubriformis. The labelled vessels were restricted to infected portions of the gut, and the intensity of labelling appeared to be re...

journal_title：Parasitology

authors： Barker IK

更新日期：1975-04-01 00:00:00

abstract：:Changes during development in the elemental contents (Ca, P, K, Mg and S) of male and female Schistosoma mansoni from both mixed and single sex infections have been measured for the first time. In mixed infections, there is a significant difference between the calcium content of male and female worms; female worms hav...

journal_title：Parasitology

authors： Shaw MK,Erasmus DA

更新日期：1983-06-01 00:00:00

abstract：:Human cysticercosis is a public health problem caused by Taenia solium metacestodes; thus, eradication of T. solium transmission by vaccination is an urgent requirement. The Cc48 mimotope from T. solium cysticerci was tested expressed in phage particles (mCc48) and chemically synthesized (sCc48) as a vaccine candidate...

journal_title：Parasitology

authors： Manhani MN,Tilelli CQ,Ribeiro VDS,Goulart LR,Costa-Cruz JM

更新日期：2020-10-01 00:00:00

abstract：:Recombinant ribosomal DNA sequences were amplified by PCR and used as probes to perform a fingerprint analysis of total DNA from different Entamoeba histolytica isolates. RFLPs obtained with one of the probes, R-1, support previous proposals that pathogenic and non-pathogenic E. histolytica are closely related, yet ge...

journal_title：Parasitology

authors： Cruz-Reyes JA,Spice WM,Rehman T,Gisborne E,Ackers JP

更新日期：1992-04-01 00:00:00

abstract：:Understanding the origin of invasive parasites and ecological transmission barriers on the distribution of mosquito-borne pathogens is enriched by molecular phylogenetic approaches now that large databases are becoming available. Here we assess the biogeographical relationships among haemosporidian blood parasites and...

journal_title：Parasitology

authors： Baillie SM,Brunton DH

更新日期：2011-12-01 00:00:00

abstract：:Mice fed 1.5 mg ochratoxin A (OTA) per kg body weight and infected with Trypanosoma brucei rhodesiense were compared with trypanosome-infected placebo-fed and uninfected OTA-fed controls. Uninfected OTA-fed mice showed fever, lethargy, facial and eyelid oedemas, mild hepatitis and nephritis, and high survival. Infecte...

journal_title：Parasitology

authors： Kibugu JK,Ngeranwa JJ,Makumi JN,Gathumbi JK,Kagira JM,Mwangi JN,Muchiri MW,Mdachi RE

更新日期：2009-03-01 00:00:00

abstract：:IgA and IgE activity against Teladorsagia circumcincta was investigated in a flock of Texel lambs following natural, mixed nematode infection among lambs. The distribution of IgA activity was similar to a gamma distribution whereas IgE activity was different. Box-Cox analysis demonstrated that X0.25 was a suitable tra...

journal_title：Parasitology

authors： Murphy L,Eckersall PD,Bishop SC,Pettit JJ,Huntley JF,Burchmore R,Stear MJ

更新日期：2010-07-01 00:00:00

abstract：:Understanding disease transmission is important to species management and human health. Host body condition, nutrition and disease susceptibility interact in a complex manner, and while the individual effects of these variables are well known, our understanding of how they interact and translate to population dynamics...

journal_title：Parasitology

authors： Tadiri CP,Dargent F,Scott ME

更新日期：2013-03-01 00:00:00

abstract：:Many zoonotic disease agents are transmitted between hosts by arthropod vectors, including fleas, but few empirical studies of host-vector-microparasite dynamics have investigated the relative importance of hosts and vectors. This study investigates the dynamics of 4 closely related Bartonella species and their flea v...

journal_title：Parasitology

authors： Telfer S,Begon M,Bennett M,Bown KJ,Burthe S,Lambin X,Telford G,Birtles R

更新日期：2007-03-01 00:00:00

abstract：:The development of microgamonts was studied in the small intestine of a 2-day-old cat after oral inoculation with 10(7) bradyzoites of Sarcocystis hirsuta. The cat was given bradyzoites in 2 doses at 2 h apart and killed 4 h later. Gamonts were seen in parasitophorous vacuoles of goblet cells in the epithelium of the ...

journal_title：Parasitology

authors： Dubey JP

更新日期：1983-02-01 00:00:00

abstract：:Administration of the immunostimulants Corynebacterium parvum, Bacillus Calmette-Guérin (BCG) or Bordetella pertussis prior to, or at the same time as, challenge with Trypanosoma congolense significantly increased survival times in mice, both of trypano-susceptible (A/J) and trypano-resistant (C57Bl) strains. The incr...

journal_title：Parasitology

authors： Murray M,Morrison WI

更新日期：1979-12-01 00:00:00

abstract：:Asparaginyl proteinases (or legumains) are a recently identified, novel class of cysteine proteinase which specifically hydrolyse peptide bonds after asparagine residues. Legumains have been implicated in the activation of cysteine proteases, particularly cathepsin B-like proteinases which are thought to help degrade ...

journal_title：Parasitology

authors： Oliver EM,Skuce PJ,McNair CM,Knox DP

更新日期：2006-08-01 00:00:00

abstract：:The lung schistosomulum of Schistosoma mansoni is the target of protective immunity in mice singly vaccinated with irradiated cercariae. Since the effector responses are T cell-mediated, their initiation requires the release of antigens from the intact parasite. We have used the technique of biosynthetic labelling wit...

journal_title：Parasitology

authors： Harrop R,Wilson RA

更新日期：1993-09-01 00:00:00

abstract：:An electron microscopical examination has been made of the fine structure and disposition of pancreatic polypeptide immunoreactive cells associated with the egg-forming apparatus in Diclidophora merlangi. The cell bodies are positioned in the parenchyma surrounding the ootype and taper to axon-like processes that exte...

journal_title：Parasitology

authors： Halton DW,Brennan GP,Maule AG,Shaw C,Johnston CF,Fairweather I

更新日期：1991-06-01 00:00:00

abstract：:An animal's social behaviour both influences and changes in response to its parasites. Here we consider these bidirectional links between host social behaviours and parasite infection, both those that occur from ecological vs evolutionary processes. First, we review how social behaviours of individuals and groups infl...

journal_title：Parasitology

authors： Hawley DM,Gibson AK,Townsend AK,Craft ME,Stephenson JF

更新日期：2020-10-23 00:00:00

abstract：:A multi-subunit antigen (native M(r) > 200 kDa, reduced M(r) 97-100 kDa) has been identified in homogenates of Trichinella spiralis larvae using affinity-purified rabbit anti-keyhole limpet haemocyanin (KLH) antibodies and its cross-reactivity with KLH was confirmed by competition blotting. The antigen was not present...

journal_title：Parasitology

authors： Modha J,Robertson WM,Kennedy MW,Kusel JR

更新日期：1994-11-01 00:00:00

abstract：:The understanding of the patterns and processes underlying the structure of parasite communities has progressed significantly in the last years; however, much of the evidence available to date on parasite community comes from unconfirmed studies. In this study the ectoparasite communities of 2 related rockfishes, Seba...

journal_title：Parasitology

authors： González MT,Oliva ME

更新日期：2006-09-01 00:00:00

abstract：:This paper reviews naturally occurring and synthetic compounds that either enhance immune defences or lower both natural and acquired immunity. Immunomodulatory agents used both for laboratory study and clinically for the management of immunologically based diseases are considered. ...

journal_title：Parasitology

authors： Nüssler AK,Thomson AW

更新日期：1992-01-01 00:00:00

abstract：:The group of haemosporidian parasites is of general interest to basic and applied science, since several species infect mammals, leading to malaria and associated disease symptoms. Although the great majority of haemosporidian parasites appear in bird hosts, as in the case of Leucocytozoon buteonis, there is little ge...

journal_title：Parasitology

authors： Chakarov N,Greiner JF,Hauser S,Schuetzmann D,Krüger O,Boerner M,Wıdera D

更新日期：2012-10-01 00:00:00

abstract：:Life-cycle stages of the microsporidia Nosema bombycis, the pathogen causing silkworm pebrine, were separated and purified by an improved method of Percoll-gradient centrifugation. Soluble protein fractions of late sporoblasts (spore precursor cells) and mature spores were analysed by two-dimensional polyacrylamide ge...

journal_title：Parasitology

authors： Cai S,Lu X,Qiu H,Li M,Feng Z

更新日期：2011-08-01 00:00:00

abstract：:The in vitro effects of 4 arylimidamides (DB811, DB786, DB750 and DB766) against the proliferative tachyzoite stage of the apicomplexan parasite Besnoitia besnoiti were investigated. These four compounds had been shown earlier to exhibit in vitro activities in the nanomolar range against the related apicomplexans Neos...

journal_title：Parasitology

authors： Cortes HC,Muller N,Boykin D,Stephens CE,Hemphill A

更新日期：2011-04-01 00:00:00

abstract：:SIV rats infected with a high dose (50,000 oocysts) of Eimeria nieschulzi displayed clinical symptoms of coccidiosis such as diarrhoea (days 6 and 7 post-primary infection) and weight loss (days 6-8 post-primary infection) and were completely immune to challenge with a similar dose. The ability of rats to produce tumo...

journal_title：Parasitology

authors： Smith NC,Ovington KS,Deplazes P,Eckert J

更新日期：1995-07-01 00:00:00

abstract：:Cryptosporidia are important protozoan parasites of vertebrates, and a number of species and genotypes, with different host ranges, have been described. In this study a protocol was established for the detection and the genetic characterization of Cryptosporidium spp. isolated from various types of surface waters (riv...

journal_title：Parasitology

authors： Ward PI,Deplazes P,Regli W,Rinder H,Mathis A

更新日期：2002-04-01 00:00:00

abstract：:A serine protease was purified 942-fold from culture supernatant of L. amazonensis promastigotes using (NH4)2SO4 precipitation followed by affinity chromatography on aprotinin-agarose and continuous elution electrophoresis by Prep Cell, yielding a total recovery of 61%. The molecular mass of the active enzyme estimate...

journal_title：Parasitology

authors： Silva-Lopez RE,Coelho MG,De Simone SG

更新日期：2005-07-01 00:00:00

abstract：:Parasites often induce behavioural changes in their host. However, it is not necessarily easy to determine whether these changes are representative of an adaptation of the parasite (parasite manipulation), an adaptive response of the host or a side-effect of infection. In a solitary parasitoid of Drosophila larvae (Le...

journal_title：Parasitology

authors： Varaldi J,Petit S,Boulétreau M,Fleury F

更新日期：2006-06-01 00:00:00

abstract：:Full-length cDNAs encoding cytosolic (SODc) and putative extracellular (SODe) Cu/Zn superoxide dismutases (SODs) from the ovine gastrointestinal parasitic nematode Haemonchus contortus have been isolated and characterized. The predicted sequences of the H. contortus SODs showed strong homology to other helminth SODs, ...

journal_title：Parasitology

authors： Liddell S,Knox DP

更新日期：1998-04-01 00:00:00