Abstract:
:IgA and IgE activity against Teladorsagia circumcincta was investigated in a flock of Texel lambs following natural, mixed nematode infection among lambs. The distribution of IgA activity was similar to a gamma distribution whereas IgE activity was different. Box-Cox analysis demonstrated that X0.25 was a suitable transformation to normalise IgE responses. The transformed IgE activity was under moderate to strong genetic control. Nine different allergens were identified by proteomic analysis. Tropomyosin was selected for further analysis. IgE activity against tropomyosin was moderately heritable and associated with decreased egg counts and with reduced body weight at the time of sampling.
journal_name
Parasitologyjournal_title
Parasitologyauthors
Murphy L,Eckersall PD,Bishop SC,Pettit JJ,Huntley JF,Burchmore R,Stear MJdoi
10.1017/S0031182010000028subject
Has Abstractpub_date
2010-07-01 00:00:00pages
1249-60issue
8eissn
0031-1820issn
1469-8161pii
S0031182010000028journal_volume
137pub_type
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