Characterization of an extracellular serine protease of Leishmania (Leishmania) amazonensis.

abstract：:The interactions in vivo between Plasmodium berghei sporozoites and Kupffer cells in rat livers were studied by transmission electron microscopy. By 10 and 15 min after inoculation, sporozoites were both free in the liver sinusoids and inside endocytotic vacuoles of the Kupffer cells. The latter cells were very active...

journal_title：Parasitology

authors： Meis JF,Verhave JP,Jap PH,Meuwissen JH

更新日期：1983-04-01 00:00:00

abstract：:The effects of dietary urea supplementation and of a 10-week trickle infection regime, simulating chronic exposure to Haemonchus contortus, on the zymogenic population of the abomasa of Hampshire Down lambs was examined. At necropsy a variety of parameters including plasma pepsinogen concentration, the wet weights of ...

journal_title：Parasitology

authors： Scott I,Stear MJ,Irvine J,Dick A,Wallace DS,McKellar QA

更新日期：1998-06-01 00:00:00

abstract：:The induction of schistosomulicidal activity of peritoneal macrophages by concanavalin A-stimulated supernatants from long-term T-cell clones and by interferon-gamma (IFN-gamma) was investigated in detail. Optimal conditions of in vitro macrophage activation by T-cell clone supernatants were established. Macrophages f...

journal_title：Parasitology

authors： Kubelka CF,Ruppel A,Krammer PH,Gemsa D

更新日期：1986-04-01 00:00:00

abstract：:Phylogenetic relationships among Trypanosoma rangeli isolates from man, wild mammals and triatomine bugs from widespread geographical origin were inferred by comparison of the small subunit of ribosomal gene sequences. The phylogenetic trees indicated that the subgenus Herpetosoma is polyphyletic and strongly supporte...

journal_title：Parasitology

authors： Da Silva FM,Noyes H,Campaner M,Junqueira AC,Coura JR,Añez N,Shaw JJ,Stevens JR,Teixeira MM

更新日期：2004-11-01 00:00:00

abstract：:The snail Bulinus nasutus 1214 possesses a potent haemagglutinin (end-point titre with human erythrocytes, 2(-18)) in its cell-free haemolymph which also binds to the miracidia (but not other larvae) of the incompatible parasite Schistosoma margrebowiei. We have purified a protein possessing this haemagglutinating pro...

journal_title：Parasitology

authors： Harris RA,Preston TM,Southgate VR

更新日期：1993-02-01 00:00:00

abstract：:The development of resistance in mice to reinfection with Schistosoma mansoni was recorded during an early chronic infection, and compared with hepatic portal pathological and vascular changes. The latter were assessed using a microsphere injection technique. The degree of acquired resistance was directly dependent on...

journal_title：Parasitology

authors： McHugh SM,Coulson PS,Wilson RA

更新日期：1987-02-01 00:00:00

abstract：:This study evaluated the effectiveness of low doses of benznidazole (BNZ) on continuous administration (BNZc), combined with allopurinol (ALO), in C57BL/6J and C3H/HeN mice infected with Trypanosoma cruzi Nicaragua strain and T. cruzi Sylvio-X10/4 clone. TcN-C57BL/6J was also treated with intermittent doses of BNZ (BN...

journal_title：Parasitology

authors： Rial MS,Scalise ML,López Alarcón M,Esteva MI,Búa J,Benatar AF,Prado NG,Riarte AR,Fichera LE

更新日期：2019-03-01 00:00:00

abstract：:We cloned and expressed Echinostoma caproni HSP70 in Escherichia coli. This molecule presents an open reading frame (ORF) of 655 amino acids, and a theoretical molecular weight of 71 kDa. E. caproni HSP70 protein showed a high homology to other helminth molecules, major differences being located in the C-terminal regi...

journal_title：Parasitology

authors： Higón M,Monteagudo C,Fried B,Esteban JG,Toledo R,Marcilla A

更新日期：2008-10-01 00:00:00

abstract：:Species composition of wild reservoir hosts can influence the transmission and maintenance of multi-host vector borne pathogens. The 'pace of life' hypothesis proposes that the life history strategy of reservoir hosts can influence pathogen transmission of vector borne generalist pathogens. We use empirical data to pa...

journal_title：Parasitology

authors： Erazo D,Cordovez J,Cabrera C,Calzada JE,Saldaña A,Gottdenker NL

更新日期：2017-12-01 00:00:00

abstract：:We studied the pattern of infection and the inter-annual variation and individual factors affecting the infection of 2 species of nasopharyngeal bot flies, Cephenemyia auribarbis and Pharyngomyia picta (Diptera: Oestridae), in a population of Iberian red deer (Cervus elaphus hispanicus) from south central Spain (10 an...

journal_title：Parasitology

authors： Vicente J,Fierro Y,Martínez M,Gortázar C

更新日期：2004-09-01 00:00:00

abstract：:The kinetoplastid parasite Trypanosoma brucei causes African trypanosomiasis in both humans and animals. Infections place a significant health and economic burden on developing nations in sub-Saharan Africa, but few effective anti-parasitic treatments are currently available. Hence, there is an urgent need to identify...

journal_title：Parasitology

authors： Dickie EA,Young SA,Smith TK

更新日期：2019-04-01 00:00:00

abstract：:Serology is an important tool for the diagnosis of alveolar echinococcosis (AE) in humans. In order to improve serodiagnostic performance, we have developed an in vitro-produced Echinococcus mulilocularis metacestode vesicle fluid (EmVF) antigen for application in an immunoblot assay. Immunoblot analysis of EmVF revea...

journal_title：Parasitology

authors： Müller N,Frei E,Nuñez S,Gottstein B

更新日期：2007-06-01 00:00:00

abstract：:This study characterized antigens of Trichinella spiralis and T. pseudospiralis muscle larvae recognized by mice infected with the worms. Two-dimensional (2-D) Western blot analysis revealed some profile of antigenic peptides including: (1) molecular weight (MW); (2) isoelectric points (pI), (3) reactivity to well-def...

journal_title：Parasitology

authors： Wu Z,Nagano I,Takahashi Y

更新日期：1999-06-01 00:00:00

abstract：:In the context of a broader program dealing with the symbiotic associations of apple snails, we sampled three species that coexist in Lake Regatas (Palermo, Buenos Aires, Argentina). The population of Asolene platae, (but not those of Pomacea canaliculata and Pomacea scalaris) showed trematode larvae (echinocercariae ...

journal_title：Parasitology

authors： Dellagnola FA,Montes MM,Martorelli SR,Vega IA

更新日期：2019-06-01 00:00:00

abstract：:The nematode-trapping fungus Arthrobotrys oligospora traps and invades all the free-living juvenile stages of the trichostrongyle nematode Trichostrongylus colubriformis. The processes of capture and invasion of the 1st-stage juveniles are described using differential interference contrast optics and 3-D reconstructio...

journal_title：Parasitology

authors： Murray DS,Wharton DA

更新日期：1990-08-01 00:00:00

abstract：:We have recently identified 2 surface proteins in Entamoeba histolytica as intermediate subunits of galactose- and N-acetyl-D-galactosamine-inhibitable lectin (EhIgl1 and EhIgl2); these proteins both contain multiple CXXC motifs. Here, we report the molecular characterization of the corresponding proteins in Entamoeba...

journal_title：Parasitology

authors： Tachibana H,Cheng XJ,Kobayashi S,Okada Y,Itoh J,Takeuchi T

更新日期：2007-12-01 00:00:00

abstract：:Avian malaria is a vector transmitted disease caused by Plasmodium and recent studies suggest that variation in its prevalence across avian hosts is correlated with a variety of ecological traits. Here we examine the relationship between prevalence and diversity of Plasmodium lineages in southeastern Amazonia and: (1)...

journal_title：Parasitology

authors： Fecchio A,Ellis VA,Bell JA,Andretti CB,D'Horta FM,Silva AM,Tkach VV,Weckstein JD

更新日期：2017-07-01 00:00:00

abstract：:Blood examination by microhaematocrit and haemoculture of 459 snakes belonging to 37 species revealed 2.4% trypanosome prevalence in species of Viperidae (Crotalus durissus and Bothrops jararaca) and Colubridae (Pseudoboa nigra). Trypanosome cultures from C. durissus and P. nigra were behaviourally and morphologically...

journal_title：Parasitology

authors： Viola LB,Campaner M,Takata CS,Ferreira RC,Rodrigues AC,Freitas RA,Duarte MR,Grego KF,Barrett TV,Camargo EP,Teixeira MM

更新日期：2008-04-01 00:00:00

abstract：:This paper reviews naturally occurring and synthetic compounds that either enhance immune defences or lower both natural and acquired immunity. Immunomodulatory agents used both for laboratory study and clinically for the management of immunologically based diseases are considered. ...

journal_title：Parasitology

authors： Nüssler AK,Thomson AW

更新日期：1992-01-01 00:00:00

abstract：:High levels of molecular diversity were identified in mitochondrial cytochrome c oxidase (cox1) gene sequences of Schistosoma turkestanicum from Hungary. These cox1 sequences were all specific to Hungary which contrasted with the low levels of diversity seen in the nuclear internal transcribed spacer region (ITS) sequ...

journal_title：Parasitology

authors： Lawton SP,Bowen LI,Emery AM,Majoros G

更新日期：2017-11-01 00:00:00

abstract：:Asparaginyl proteinases (or legumains) are a recently identified, novel class of cysteine proteinase which specifically hydrolyse peptide bonds after asparagine residues. Legumains have been implicated in the activation of cysteine proteases, particularly cathepsin B-like proteinases which are thought to help degrade ...

journal_title：Parasitology

authors： Oliver EM,Skuce PJ,McNair CM,Knox DP

更新日期：2006-08-01 00:00:00

abstract：:The World Health Organization announced in November 2014 at the fourth international meeting on 'the control of neglected zoonotic diseases - from advocacy to action', that intervention tools for eliminating Taenia solium taeniosis/cysticercosis (TSTC) are in place. The aim of this work was to elucidate theoretical ou...

journal_title：Parasitology

authors： Johansen MV,Trevisan C,Gabriël S,Magnussen P,Braae UC

更新日期：2017-01-01 00:00:00

abstract：:Given the worldwide decline of amphibian populations due to emerging infectious diseases, it is imperative that we identify and address the causative agents. Many of the pathogens recently implicated in amphibian mortality and morbidity have been fungal or members of a poorly understood group of fungus-like protists, ...

journal_title：Parasitology

authors： Raffel TR,Bommarito T,Barry DS,Witiak SM,Shackelton LA

更新日期：2008-02-01 00:00:00

abstract：:Multiplication of virulent and avirulent Leishmania donovani promastigotes was inhibited by brain heart infusion broth (BHI) (3.7%) supplemented with haemolysed or whole blood (2.5-10%) or heat-inactivated foetal bovine serum (HIFBS) (10-20%). Peptone, glutamine, tryptophan, purine bases, ribonucleosides, deoxyribonuc...

journal_title：Parasitology

authors： Kar K

更新日期：1997-09-01 00:00:00

abstract：:Actively immunized mice, whole-body irradiated with 650 or 525 rad., manifested comparable levels of resistance to Schistosoma mansoni compared with unirradiated, immunized mice in spite of a marked reduction in circulating leucocytes (greater than 90%) and platelets (greater than 85%), and despite an abrogation of de...

journal_title：Parasitology

authors： Vignali DA,Bickle QD,Taylor MG

更新日期：1988-02-01 00:00:00

abstract：:The effect of sainfoin (Onobrychis viciifolia) hay consumption on the pathophysiology and local cellular responses of growing lambs during infection with Trichostrongylus colubriformis was investigated. Thirty-two lambs, 16 weeks of age, were allocated to 1 of 4 treatment groups (n=8) that were offered either grass (G...

journal_title：Parasitology

authors： Ríos-de Alvarez L,Greer AW,Jackson F,Athanasiadou S,Kyriazakis I,Huntley JF

更新日期：2008-08-01 00:00:00

abstract：:The respiratory chain of the procyclic stage of Trypanosoma brucei contains the standard complexes I through IV, as well as several alternative enzymes contributing to electron flow. In this work, we studied the function of an alternative NADH : ubiquinone oxidoreductase (NDH2). Depletion of target mRNA was achieved u...

journal_title：Parasitology

authors： Verner Z,Skodová I,Poláková S,Durišová-Benkovičová V,Horváth A,Lukeš J

更新日期：2013-03-01 00:00:00

abstract：:The tegumental surface of Schistosoma mansoni sporocysts is the site of both nutritive and immunological interactions with haemolymph cells and plasma of Biomphalaria glabrata, the schistosome intermediate host. Within minutes of being placed in host plasma, sporocysts acquire plasma antigens, and within 3 h host plas...

journal_title：Parasitology

authors： Bayne CJ,Loker ES,Yui MA

更新日期：1986-06-01 00:00:00

abstract：:Protoscoleces of Echinococcus granulosus absorb the L-amino acids proline, methionine, leucine, alanine, serine, phenylalanine, lysine and glutamic acid by a combination of mediated transport and diffusion. All eight amino acids were accumulated against a concentration gradient. Comparison of Kt and Vmax values sugges...

journal_title：Parasitology

authors： Jeffs SA,Arme C

更新日期：1987-08-01 00:00:00

abstract：:In areas where malaria is endemic, helminthic infections, caused by intestinal or filarial parasites, commonly coexist with malaria in the same individual. This study investigates the course of Plasmodium berghei malaria infection in CBA/J mice inoculated with irradiated attenuated 3rd-stage larvae (L3) of Brugia paha...

journal_title：Parasitology

authors： Yan Y,Inuo G,Akao N,Tsukidate S,Fujita K

更新日期：1997-04-01 00:00:00