Echinococcus granulosus: specificity of amino acid transport systems in protoscoleces.

Abstract:

:Protoscoleces of Echinococcus granulosus absorb the L-amino acids proline, methionine, leucine, alanine, serine, phenylalanine, lysine and glutamic acid by a combination of mediated transport and diffusion. All eight amino acids were accumulated against a concentration gradient. Comparison of Kt and Vmax values suggests that a low affinity for a particular compound is compensated for by a relatively larger number of transport sites for that compound. Four systems serve for the transport of the eight substrates studied: 2 for neutral (EgN1, EgN2) and 1 each for acidic (EgA) and basic (EgB) amino acids. All eight amino acids are incorporated into protein to varying degrees and substantial portions of absorbed L-alanine and L-methionine are metabolized into other compounds.

journal_name

Parasitology

journal_title

Parasitology

authors

Jeffs SA,Arme C

doi

10.1017/s0031182000057553

subject

Has Abstract

pub_date

1987-08-01 00:00:00

pages

71-8

eissn

0031-1820

issn

1469-8161

journal_volume

95 ( Pt 1)

pub_type

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