Cytosolic glutathione S-transferases of Oesophagostomum dentatum.

abstract：:We have cloned a cDNA encoding a novel antigen from a Sarcoptes scabiei (Acari) cDNA library by immunoscreening with sera from S. scabiei-infected dogs. The antigen is encoded by a 2,157 bp mRNA with a predicted open reading frame of 719 amino acids (molecular weight 79 kDa). Our sequence analysis identified the prese...

journal_title：Parasitology

authors： Ljunggren EL,Bergström K,Morrison DA,Mattsson JG

更新日期：2006-01-01 00:00:00

abstract：:A deterministic mathematical model which predicts the probability of developing a new drug-resistant parasite population within the human host is reported. The model incorporates the host's specific antibody response to PfEMP1, and also investigates the influence of chemotherapy on the probability of developing a viab...

journal_title：Parasitology

authors： Gatton ML,Hogarth W,Saul A

更新日期：2001-12-01 00:00:00

abstract：:A field trial was conducted to evaluate the potential of the nematode-destroying fungus Duddingtonia flagrans to control free-living stages of horse strongyles. In late Spring 2 groups of horses (yearlings) with mixed infections of strongyles were allowed to contaminate 2 equal-sized pastures. One of the groups (F) re...

journal_title：Parasitology

authors： Larsen M,Nansen P,Grøndahl C,Thamsborg SM,Grønvold J,Wolstrup J,Henriksen SA,Monrad J

更新日期：1996-07-01 00:00:00

abstract：:The occurrence of multiple-clone Plasmodium falciparum haploid blood-stage infections is a pre-requisite for cross-fertilization and genetic exchange at the diploid stage in the mosquito. Using monoclonal antibodies against 3 polymorphic blood-stage antigens, a method of two-colour differential immunofluorescence allo...

journal_title：Parasitology

authors： Conway DJ,Greenwood BM,McBride JS

更新日期：1991-08-01 00:00:00

abstract：:Conventional mice and congenitally athymic, nude mice were infected with 20 metacercariae of the intestinal trematode Echinostoma revolutum. The sequential events in the pathological changes in the intestine were studied at different intervals post-infection. By day 11 onwards the conventional mice displayed dilatatio...

journal_title：Parasitology

authors： Bindseil E,Christensen NO

更新日期：1984-06-01 00:00:00

abstract：:Although the rumen fluke, Calicophoron daubneyi is now very common and widespread throughout Western Europe, reports of clinical cases are still rare. This study explores the epidemiological background to a severe rumen fluke outbreak in 6-month-old heifers on a dairy farm in Ireland. Sequence analysis of the cytochro...

journal_title：Parasitology

authors： O'Shaughnessy J,Garcia-Campos A,McAloon CG,Fagan S,de Waal T,McElroy M,Casey M,Good B,Mulcahy G,Fagan J,Murphy D,Zintl A

更新日期：2018-06-01 00:00:00

abstract：:The localization of adult Schistosoma mansoni originating from Guadeloupe (West Indies) was analysed in the natural host Rattus rattus in experimental and natural infections. A transfer of schistosomes from the porto-mesenteric system to the lungs occurs between the 4th and the 20th weeks post-infection, with a peak b...

journal_title：Parasitology

authors： Imbert-Establet D,Combes C

更新日期：1992-02-01 00:00:00

abstract：:Asparaginyl proteinases (or legumains) are a recently identified, novel class of cysteine proteinase which specifically hydrolyse peptide bonds after asparagine residues. Legumains have been implicated in the activation of cysteine proteases, particularly cathepsin B-like proteinases which are thought to help degrade ...

journal_title：Parasitology

authors： Oliver EM,Skuce PJ,McNair CM,Knox DP

更新日期：2006-08-01 00:00:00

abstract：:The tegumental surface of Schistosoma mansoni sporocysts is the site of both nutritive and immunological interactions with haemolymph cells and plasma of Biomphalaria glabrata, the schistosome intermediate host. Within minutes of being placed in host plasma, sporocysts acquire plasma antigens, and within 3 h host plas...

journal_title：Parasitology

authors： Bayne CJ,Loker ES,Yui MA

更新日期：1986-06-01 00:00:00

abstract：:Tubulin is the predominant phosphoprotein in Trypanosoma cruzi epimastigotes and is phosphorylated by a protein kinase CK2. Interestingly, the presence or absence of divalent cations affected the solubilization of a pool of the parasite tubulin and the CK2 responsible for its phosphorylation. This fraction of tubulin ...

journal_title：Parasitology

authors： De Lima AR,Medina R,Uzcanga GL,Noris Suárez K,Contreras VT,Navarro MC,Arteaga R,Bubis J

更新日期：2006-04-01 00:00:00

abstract：:The ultrastructure of the formation of the first-stage cuticle within the egg of Trichostrongylus colubriformis is described. The first indication of cuticle formation was the formation of the epicuticle external to the epidermal plasma membrane. This becomes thickened to form the epicuticle of the fully formed cuticl...

journal_title：Parasitology

authors： Wharton DA,Bone LW

更新日期：1988-12-01 00:00:00

abstract：:Intraerythrocytic malaria parasites ingest the cytosol of their host cell and digest it inside their acid food vacuoles. Acidified (pH 4-5.5, 37 degrees C) human red blood cell lysates were used to simulate this process, measuring the denaturation of haemoglobin (Hb) and the release of iron, in the absence or presence...

journal_title：Parasitology

authors： Gabay T,Krugliak M,Shalmiev G,Ginsburg H

更新日期：1994-05-01 00:00:00

abstract：:Existing models of the basic case reproduction number (R0) for vector-borne diseases assume (i) that the distribution of vectors over the susceptible host species is homogeneous and (ii) that the biting preference for the susceptible host species rather than other potential hosts is a constant. Empirical evidence cont...

journal_title：Parasitology

authors： Kelly DW,Thompson CE

更新日期：2000-03-01 00:00:00

abstract：:The use of parasites as biological tags to discriminate among marine fish stocks has become a widely accepted method in fisheries management. Here, we first link this approach to its unstated ecological foundation, the decay in the similarity of the species composition of assemblages as a function of increasing distan...

journal_title：Parasitology

authors： Poulin R,Kamiya T

更新日期：2015-01-01 00:00:00

abstract：:The development of a successful vaccine depends not only on the production of the vaccine itself, but also on the design pf the vaccination programme. This involves a better understanding of the epidemiology of the disease to be controlled, the delivery system to be used and the costs involved. This review focuses on ...

journal_title：Parasitology

authors： Bundy DA,Chan MS,Guyatt HL

更新日期：1995-01-01 00:00:00

abstract：:Little is known about the effects of infection with Borrelia burgdorferi, the bacterium that causes Lyme disease, on its tick vectors. The purpose of this study was to determine the behavioural and ecological effects of infection by the bacterium in nymphal and adult black-legged (Ixodes scapularis) ticks. We found th...

journal_title：Parasitology

authors： Lefcort H,Durden LA

更新日期：1996-08-01 00:00:00

abstract：:Isolates of Trypanosoma cruzi from human patients, domestic and sylvatic animals and vector insects were obtained in different areas of Argentina. Electrophoretic patterns of enzymes from extracts of 95 isolates were analysed. On the basis of zymograms providing information on 10 loci, 12 zymodemes are described accor...

journal_title：Parasitology

authors： de Luca D'oro GM,Gardenal CN,Perret B,Crisci JV,Montamat EE

更新日期：1993-11-01 00:00:00

abstract：:Cystic echinococcosis (CE) is a high prevalence zoonosis among the rural population of Tacuarembó (Uruguay). The correlation between serological data and the incidence of risk factors was studied in a survey carried out in 1998 among rural communities where 480 individuals were examined by means of abdominal sonograph...

journal_title：Parasitology

authors： Hernández A,Cardozo G,Dematteis S,Baz A,Trias N,Nuñez H,Barragué A,López L,Fuentes J,López O,Ferreira C

更新日期：2005-04-01 00:00:00

abstract：:We have studied the genomic organization and transcription of the histone H2A genes in the protozoan parasite Leishmania infantum. In the parasite genome 2 gene clusters exist, each containing 3 H2A gene copies. Sequence analyses showed the existence of significant sequence divergence among the H2A genes, mainly in th...

journal_title：Parasitology

authors： Soto M,Quijada L,Larreta R,Iborra S,Alonso C,Requena JM

更新日期：2003-08-01 00:00:00

abstract：:Nematodes are amongst the most successful and abundant organisms on the planet with approximately 30 000 species described, although the actual number of species is estimated to be one million or more. Despite sharing a relatively simple and invariant body plan, there is considerable diversity within the phylum. Nemat...

journal_title：Parasitology

authors： Gillan V,Devaney E

更新日期：2014-08-01 00:00:00

abstract：:Chagas infection is a major endemic disease affecting Latin American countries. The persistence of Trypanosoma cruzi generates a chronic inflammatory reactivity that induces an immune response directed to the host's tissues. The effectiveness of the treatment in the chronic phase is still unsatisfactory due, amongst o...

journal_title：Parasitology

authors： Fauro R,Lo Presti S,Bazan C,Baez A,Strauss M,Triquell F,Cremonezzi D,Negrete OS,Willhuber GC,Paglini-Oliva P,Rivarola HW

更新日期：2013-06-01 00:00:00

abstract：:In parallel with massive research efforts in human schistosomiasis over the past 30 years, persistent efforts have been made to understand the basis for compatibility and incompatibility in molluscan schistosomiasis. Snail plasma contains molecules that are toxic to trematodes, but these seem to kill only species that...

journal_title：Parasitology

authors： Bayne CJ,Hahn UK,Bender RC

更新日期：2001-01-01 00:00:00

abstract：:A procedure is described for the isolation of sub-cellular fractions from bloodstream forms of Trypanosoma brucei. The method leaves intact most of the nuclei, mitochondria and microbodies. All the fractions have been chemically characterized and tested for 10 enzymatic markers. About 5% of total cell protein was isol...

journal_title：Parasitology

authors： Rovis L,Baekkeskov S

更新日期：1980-06-01 00:00:00

abstract：:Infection with the endosymbiotic bacteria Wolbachia is widespread in filarial nematodes. Previous studies have suggested concordance between the phylogeny of Wolbachia with that of their nematode hosts. However, there is only one published molecular phylogenetic study of filarial species, based on the 5S rRNA gene spa...

journal_title：Parasitology

authors： Casiraghi M,Anderson TJ,Bandi C,Bazzocchi C,Genchi C

更新日期：2001-01-01 00:00:00

abstract：:The capacity of Acanthocheilonema viteae to metabolize fructose was investigated in vitro. In common with other filarial species A. viteae oxidized fructose to lactate but its rate of consumption was only 40% of the glucose-containing control value. Fructose was not incorporated into glycogen. Release of 14CO2 from [U...

journal_title：Parasitology

authors： Hayes DJ,Carter NS

更新日期：1990-12-01 00:00:00

abstract：:Trypanosoma brucei is the causative agent of African sleeping sickness in humans and one of several pathogens that cause the related veterinary disease Nagana. A complex co-evolution has occurred between these parasites and primates that led to the emergence of trypanosome-specific defences and counter-measures. The f...

journal_title：Parasitology

authors： Capewell P,Cooper A,Clucas C,Weir W,Macleod A

更新日期：2015-02-01 00:00:00

abstract：:The surface morphology of fixed ovarian balls from female Moniliformis dubius, agd 12, 18, 26, 28, 42, 77, 105 and 118 days, has been examined by means of scanning electron microscopy. The appearance of the surface has been found to be variable between ovarian balls from worms of the same and different ages. Some part...

journal_title：Parasitology

authors： Parshad VR,Crompton DW,Martin J

更新日期：1980-10-01 00:00:00

abstract：:The structure and development of microgametocytes pf Eimeria maxima from chicks killed during the 6th day of infection were examined using transmission and scanning electron microscopy. Initially, nucleoli disappear and the surface of the microgametocyte invaginates. This is followed by a condensation of the chromatin...

journal_title：Parasitology

authors： Ball SJ,Pittilo RM,Joyner LP,Norton CC

更新日期：1981-02-01 00:00:00

abstract：:Cysteine proteases of pathogenic protozoan parasites play pivotal roles in the life cycle of parasites, but strict regulation of their activities is also essential for maintenance of parasite physiology and interaction with hosts. In this study, we identified and characterized cryptostatin, a novel inhibitor of cystei...

journal_title：Parasitology

authors： Kang JM,Ju HL,Yu JR,Sohn WM,Na BK

更新日期：2012-07-01 00:00:00

abstract：:Mice fed 1.5 mg ochratoxin A (OTA) per kg body weight and infected with Trypanosoma brucei rhodesiense were compared with trypanosome-infected placebo-fed and uninfected OTA-fed controls. Uninfected OTA-fed mice showed fever, lethargy, facial and eyelid oedemas, mild hepatitis and nephritis, and high survival. Infecte...

journal_title：Parasitology

authors： Kibugu JK,Ngeranwa JJ,Makumi JN,Gathumbi JK,Kagira JM,Mwangi JN,Muchiri MW,Mdachi RE

更新日期：2009-03-01 00:00:00