Abstract:
:Cystic echinococcosis (CE) is a high prevalence zoonosis among the rural population of Tacuarembó (Uruguay). The correlation between serological data and the incidence of risk factors was studied in a survey carried out in 1998 among rural communities where 480 individuals were examined by means of abdominal sonography (local prevalence = 0.8%). Serum samples (305) were analysed by ELISA to determine specific IgG against crude antigens from Echinococcus granulosus. A total of 27 individuals exhibiting no detectable changes in abdominal sonographic examination were found to be seropositive ('ultrasound normal group'). Of these individuals 9 were seroreactive against purified antigen B. A significant degree of correlation was found between seroreactivity and the incidence of some risk factors (CE antecedent in the family, P < 0.005 and use of rural water, P < 0.0001) among this group. Follow-up of individuals of the 'ultrasound normal group' was carried out after 2 years to evaluate the implications of this serological reactivity. No predictive value for cyst development was assessed with complementary image study; in contrast transient antibodies were observed with both crude and purified antigen as approximately 60% of individuals became negative when re-sampled.
journal_name
Parasitologyjournal_title
Parasitologyauthors
Hernández A,Cardozo G,Dematteis S,Baz A,Trias N,Nuñez H,Barragué A,López L,Fuentes J,López O,Ferreira Cdoi
10.1017/s0031182004006717subject
Has Abstractpub_date
2005-04-01 00:00:00pages
455-60issue
Pt 4eissn
0031-1820issn
1469-8161journal_volume
130pub_type
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