A novel assay for the detection of anthelmintic activity mediated by cuticular damage to nematodes: validation on Caenorhabditis elegans exposed to cysteine proteinases.

abstract：:Harnessing the full utility of extensive gene sequences recently available for the economically important sea louse, Lepeophtheirus salmonis, requires the adaptation of modern molecular biology approaches to this non-model organism. Using a putative microsomal prostaglandin E synthase type-2 (PGES2) as a candidate gen...

journal_title：Parasitology

authors： Campbell EM,Pert CC,Bowman AS

更新日期：2009-07-01 00:00:00

abstract：:Adult Onchocerca volvulus worms obtained by enzyme digestion from nodules of infected Mexicans were radio-isotope labelled by the chloramine-T or Bolton-Hunter methods. No antigenic determinants were detected in extracts of worms labelled by the chloramine-T method but 3 antigens were detected in extracts of the Bolto...

journal_title：Parasitology

authors： Philipp M,Gómez-Priego A,Parkhouse RM,Davies MW,Clark NW,Ogilvie BM,Beltrán-Hernández F

更新日期：1984-10-01 00:00:00

abstract：:Host behavioural modification by parasites is a common and well-documented phenomenon. However, knowledge on the complexity and specificity of the underlying mechanisms is limited, and host specificity among manipulating parasites has rarely been experimentally verified. We tested the hypothesis that the ability to in...

journal_title：Parasitology

authors： Hernandez RN,Fredensborg BL

更新日期：2015-11-01 00:00:00

abstract：:Host-parasite interactions are shaped by the co-evolutionary arms race of parasite virulence, transmission success as well as host resistance and recovery. The virulence and fitness of parasites may depend on host condition, which is mediated, for instance, by host energy constraints. Here, we investigated to what ext...

journal_title：Parasitology

authors： Coors A,De Meester L

更新日期：2011-01-01 00:00:00

abstract：:The complete nucleotide sequence of the mitochondrial genome was determined for the fish tapeworm Diphyllobothrium latum. This genome is 13,608 bp in length and encodes 12 protein-coding genes (but lacks the atp8), 22 transfer RNA (tRNA) and 2 ribosomal RNA (rRNA) genes, corresponding to the gene complement found thus...

journal_title：Parasitology

authors： Park JK,Kim KH,Kang S,Jeon HK,Kim JH,Littlewood DT,Eom KS

更新日期：2007-05-01 00:00:00

abstract：:This paper reviews naturally occurring and synthetic compounds that either enhance immune defences or lower both natural and acquired immunity. Immunomodulatory agents used both for laboratory study and clinically for the management of immunologically based diseases are considered. ...

journal_title：Parasitology

authors： Nüssler AK,Thomson AW

更新日期：1992-01-01 00:00:00

abstract：:The evolution of host specificity and the potential trade-off between being a generalist and a specialist are central issues in the evolutionary ecology of parasites. Different species of parasites or even different populations of the same species often show different degrees of host specificity. However, less is know...

journal_title：Parasitology

authors： Leung TL,Poulin R

更新日期：2010-02-01 00:00:00

abstract：:The multicopy mini-exon-derived RNA (med RNA) locus of Leishmania donovani was enzymatically amplified by the polymerase chain reaction (PCR). The major 180 bp PCR product contained conserved med RNA gene sequences flanking the variable intergenic spacer from the med RNA gene tandem repeat. The oligonucleotide primers...

journal_title：Parasitology

authors： Hassan MQ,Ghosh A,Ghosh SS,Gupta M,Basu D,Mallik KK,Adhya S

更新日期：1993-12-01 00:00:00

abstract：:Many zoonotic disease agents are transmitted between hosts by arthropod vectors, including fleas, but few empirical studies of host-vector-microparasite dynamics have investigated the relative importance of hosts and vectors. This study investigates the dynamics of 4 closely related Bartonella species and their flea v...

journal_title：Parasitology

authors： Telfer S,Begon M,Bennett M,Bown KJ,Burthe S,Lambin X,Telford G,Birtles R

更新日期：2007-03-01 00:00:00

abstract：:A dipstick dot ELISA for detection of Taenia-specific coproantigens was developed. The test was based on a sandwich ELISA using antibodies raised against adult Taenia solium. Antibodies were absorbed to nitrocellulose paper previously adhered to acetate plastic to form dipsticks. Once blocked with 5% skimmed milk and ...

journal_title：Parasitology

authors： Allan JC,Mencos F,Garcia-Noval J,Sarti E,Flisser A,Wang Y,Liu D,Craig PS

更新日期：1993-07-01 00:00:00

abstract：:Why do parasites kill their hosts? During this past decade, research in three different areas; evolutionary ecology, medical microbiology, and population genetics has provided theory and data that address this and related questions of selection and the evolution and maintenance of parasite virulence. A general theory ...

journal_title：Parasitology

authors： Levin BR,Svanborg Edén C

更新日期：1990-01-01 00:00:00

abstract：:Voltage-gated calcium (Ca2+) channels contribute to impulse propagation in excitable cells and also regulate intracellular levels of Ca2+. High voltage-activated (HVA) Ca2+ channels are heteromultimeric membrane proteins. The pore-forming, voltage-sensing subunit is the alpha1 subunit. We have cloned 3 HVA Ca2+ channe...

journal_title：Parasitology

authors： Kohn AB,Lea J,Roberts-Misterly JM,Anderson PA,Greenberg RM

更新日期：2001-11-01 00:00:00

abstract：:Stability of trichostrogylid populations indicates that some form of density-dependent regulation occurs which could act through fecundity. We present evidence for intraspecific density-dependent effects in 1 of 2, dominant, abomasal nematodes species (Ostertagia gruehneri) of Svalbard reindeer (Rangifer tarandus plat...

journal_title：Parasitology

authors： Irvine RJ,Stien A,Dallas JF,Halvorsen,Langvatn R,Albon SD

更新日期：2001-06-01 00:00:00

abstract：:Cryptosporidia are important protozoan parasites of vertebrates, and a number of species and genotypes, with different host ranges, have been described. In this study a protocol was established for the detection and the genetic characterization of Cryptosporidium spp. isolated from various types of surface waters (riv...

journal_title：Parasitology

authors： Ward PI,Deplazes P,Regli W,Rinder H,Mathis A

更新日期：2002-04-01 00:00:00

abstract：:Protective immunity against larval Taenia crassiceps has been shown to rely on T cells; however, the roles of the specific subsets of T cells during infection are not known. To investigate a possible role for gamma delta T cells, this study investigated larval infection in delta-chain knock-out C57BL/6 (deltaKO) and w...

journal_title：Parasitology

authors： Toenjes SA,Spolski RJ,Mooney KA,Kuhn RE

更新日期：1999-10-01 00:00:00

abstract：:A mathematical model of the transmission dynamics of Cowdria ruminantium by the ixodid tick Amblyomma hebraeum in the bovine host is developed and used to investigate the epidemiology of heartwater across a range of vector challenge. The processes described are supported by empirical data. The pattern of outcome measu...

journal_title：Parasitology

authors： O'Callaghan CJ,Medley GF,Peter TF,Perry BD

更新日期：1998-07-01 00:00:00

abstract：:We conducted the first comprehensive study on the spatiotemporal structure of trematode communities in the large-mouthed valve snail, Valvata macrostoma. A total of 1103 snails were examined monthly between May and October 2007 from Lake Konnevesi, Central Finland, from a shallow (1-2 m deep) and an offshore site (5-6...

journal_title：Parasitology

authors： Faltýnková A,Valtonen ET,Karvonen A

更新日期：2008-12-01 00:00:00

abstract：:Nematophagous fungi are used in the biological control of the parasitic helminths of animals and plants. The association of ovicidal and predator nematophagous fungi may present a complementary and increased action on the biological control of helminths. Joint growth compatibility and predation tests were carried out ...

journal_title：Parasitology

authors： Vieira ÍS,Oliveira IC,Campos AK,Araújo JV

更新日期：2019-09-01 00:00:00

abstract：:Merocyanin 540 (Mc540) is a fluorescent compound which is thought to bind to membranes in which there are substantial amounts of lipid in the lipid-crystalline phase. It is shown here to be of value in detecting the transformation by both mechanical and skin-penetration methods of the cercaria to the schistosomulum. T...

journal_title：Parasitology

authors： Foley M,Kusel JR,Garland PB

更新日期：1988-02-01 00:00:00

abstract：:This study describes morphological changes during capsule formation of Trichinella spiralis with emphasis on nuclei within the capsule. The nuclei of the pre-existing muscle cell may become hypertrophied or degrade soon after the entrance of newborn larvae. Cytoplasm associated with these hypertrophied nuclei was baso...

journal_title：Parasitology

authors： Matsuo A,Wu Z,Nagano I,Takahashi Y

更新日期：2000-08-01 00:00:00

abstract：:Full-length cDNAs encoding cytosolic (SODc) and putative extracellular (SODe) Cu/Zn superoxide dismutases (SODs) from the ovine gastrointestinal parasitic nematode Haemonchus contortus have been isolated and characterized. The predicted sequences of the H. contortus SODs showed strong homology to other helminth SODs, ...

journal_title：Parasitology

authors： Liddell S,Knox DP

更新日期：1998-04-01 00:00:00

abstract：:Vertically transmitted parasites (VTPs) such as Wolbachia are expected not only to minimize the damage they inflict on their hosts, but also to protect their hosts against the damaging effects of coinfecting parasites. By modifying the fitness costs of the infection, VTPs can therefore play an important role in the ev...

journal_title：Parasitology

authors： Zélé F,Denoyelle J,Duron O,Rivero A

更新日期：2018-05-01 00:00:00

abstract：:The complex life-cycles of parasitic animals are a product of exploiting the process of development to generate organisms with different biological potentials within a species. Successive stages of the parasite adapt to functions such as host invasion and transmission, and to the colonization of a variety of niches, o...

journal_title：Parasitology

authors： Bianco AE,Maizels RM

更新日期：1989-01-01 00:00:00

abstract：:A specific enzyme-linked immunosorbent assay, based on a 48 kDa metallo-proteinase isolated from the frontal glands of a porocephalid pentastomid (Porocephalus crotali) in rat intermediate hosts, is described. SDS-PAGE analysis of whole nymphal homogenate, followed by Western blotting and probing with immune rat serum...

journal_title：Parasitology

authors： Jones DA,Riley J

更新日期：1991-12-01 00:00:00

abstract：:Landscape epidemiology and landscape genetics combine advances in molecular techniques, spatial analyses and epidemiological models to generate a more real-world understanding of infectious disease dynamics and provide powerful new tools for the study of RNA viruses. Using dog rabies as a model we have identified how ...

journal_title：Parasitology

authors： Brunker K,Hampson K,Horton DL,Biek R

更新日期：2012-12-01 00:00:00

abstract：:Transmission experiments were conducted to compare the transmissibility of genetically different Trypanosoma congolense (Savannah subgroup) strains isolated from cattle in a trypanosomiasis endemic area of eastern Zambia. A total of 17 strains were compared. Three strains were extremely virulent with a short pre-paten...

journal_title：Parasitology

authors： Masumu J,Marcotty T,Ndeledje N,Kubi C,Geerts S,Vercruysse J,Dorny P,van den Bossche P

更新日期：2006-09-01 00:00:00

abstract：:Analysis of the electrical properties of neurons in the motornervous system of Ascaris sutom suggests that it is largely an analogue system. The motorneurons do not conduct action potentials and they release transmitter tonically at their normal resting potential; transmitter release is increased or decreased as a con...

journal_title：Parasitology

authors： Davis RE,Stretton AO

更新日期：1996-01-01 00:00:00

abstract：:Interferon-gamma (IFN-gamma) has a crucial role for host defence against parasite infection. It is not clear, however, how IFN-gamma affects the parasite-infected host cells. The effect of IFN-gamma on Neospora caninum-infected cells was investigated in murine fibroblasts and canine kidney cells in vitro. In the prese...

journal_title：Parasitology

authors： Nishikawa Y,Mishima M,Nagasawa H,Igarashi I,Fujisaki K,Otsuka H,Mikami T

更新日期：2001-07-01 00:00:00

abstract：:Protoscoleces of Echinococcus granulosus absorb the L-amino acids proline, methionine, leucine, alanine, serine, phenylalanine, lysine and glutamic acid by a combination of mediated transport and diffusion. All eight amino acids were accumulated against a concentration gradient. Comparison of Kt and Vmax values sugges...

journal_title：Parasitology

authors： Jeffs SA,Arme C

更新日期：1987-08-01 00:00:00

abstract：:A 196 bp fragment of cloned kinetoplast (k) DNA of Leishmania infantum has been sequenced and shown to be diagnostic for this species. The DNA from 10(4)-10(5) promastigotes was routinely and specifically detected in crude dot blots of whole cells lysed in situ, and there was no cross-hybridization with 10(6) cells of...

journal_title：Parasitology

authors： Gramiccia M,Smith DF,Angelici MC,Ready PD,Gradoni L

更新日期：1992-08-01 00:00:00