A novel assay for the detection of anthelmintic activity mediated by cuticular damage to nematodes: validation on Caenorhabditis elegans exposed to cysteine proteinases.

abstract：:Endosymbiotic bacteria of the genus Wolbachia infect a number of invertebrate species in which they induce various alterations in host reproduction, mainly cytoplasmic incompatibility (CI). In contrast to most other maternally transmitted parasites, manipulation of host reproduction makes the spread of Wolbachia possi...

journal_title：Parasitology

authors： Fleury F,Vavre F,Ris N,Fouillet P,Boulétreau M

更新日期：2000-11-01 00:00:00

abstract：:Cyst fluid (CF) of Taenia solium metacestode (TsM) is an important source of serodiagnostic antigens. We have investigated the molecular characteristics of the 120 kDa protein complex in TsM CF purified by fast performance liquid chromatography. The structure of the purified protein was characterized by a variety of p...

journal_title：Parasitology

authors： Lee EG,Bae YA,Jeong YT,Chung JY,Je EY,Kim SH,Na BK,Ju JW,Kim TS,Ma L,Cho SY,Kong Y

更新日期：2005-12-01 00:00:00

abstract：:Of the 7 genetic assemblages of the parasite Giardia duodenalis only 2 (A and B) are known to cause infections in humans. These assemblages have been characterized in detail at the genomic level but few studies have examined differences in the proteins expressed. Employing one and two-dimensional PAGE we have identifi...

journal_title：Parasitology

authors： Steuart RF,O'Handley R,Lipscombe RJ,Lock RA,Thompson RC

更新日期：2008-12-01 00:00:00

abstract：:Due to the low informative value of available morphological characters, cytogenetic and molecular methods, based on rDNA sequencing, were used to characterize adult and larval stages of Phyllodistomum spp. Species studied have 18 chromosomes with comparable absolute and relative lengths. Conventional Giemsa staining a...

journal_title：Parasitology

authors： Petkeviciŭte R,Stunzenas V,Staneviciŭte G

更新日期：2004-12-01 00:00:00

abstract：:This study quantifies the rate and intensity of re-infection with human hookworm and Schistosoma mansoni infection 12 months following successful treatment, and investigates the influence of socio-economic, geographical and environmental factors. A longitudinal study of 642 individuals aged over 5 years was conducted ...

journal_title：Parasitology

authors： Cundill B,Alexander N,Bethony JM,Diemert D,Pullan RL,Brooker S

更新日期：2011-09-01 00:00:00

abstract：:Blastocystis SSU-rDNA sequence data from 317 captive and free-living non-human primates (NHPs) representing 30 genera of apes, Old and New World (OW and NW) monkeys and prosimians were analysed to investigate subtype (ST) and allele distribution among hosts. Excluding 20 mixed ST infections, 27% of the sequences belon...

journal_title：Parasitology

authors： Alfellani MA,Jacob AS,Perea NO,Krecek RC,Taner-Mulla D,Verweij JJ,Levecke B,Tannich E,Clark CG,Stensvold CR

更新日期：2013-07-01 00:00:00

abstract：:Understanding disease transmission is important to species management and human health. Host body condition, nutrition and disease susceptibility interact in a complex manner, and while the individual effects of these variables are well known, our understanding of how they interact and translate to population dynamics...

journal_title：Parasitology

authors： Tadiri CP,Dargent F,Scott ME

更新日期：2013-03-01 00:00:00

abstract：:We investigated the segregation of an intracellular microsporidian parasite during host cell division. A time-course experiment was carried out to examine the distribution of parasites relative to host chromosomal DNA via light and electron microscopy. Fluorescent light microscopy and EM studies showed that the parasi...

journal_title：Parasitology

authors： Terry RS,Dunn AM,Smith JE

更新日期：1999-01-01 00:00:00

abstract：:A comparison has been made of the interactions between passively transferred and actively acquired immunity in regulating populations of Taenia hydatigena and T. ovis. When ewes were grazed prior to parturition under a high infection pressure, immunity was transferred to their offspring for up to 8 weeks. A qualitativ...

journal_title：Parasitology

authors： Gemmell MA,Lawson JR,Roberts MG,Griffin JF

更新日期：1990-08-01 00:00:00

abstract：:Leishmania braziliensis strain M2903 was adapted for growth and serially maintained as amastigotes at 34 degrees C in modified UM-54 medium, with growth curves exhibiting typical log and stationary phases. In late passages, amastigote growth took place in the absence of supplementary haemin and was unaffected when the...

journal_title：Parasitology

authors： Balanco JM,Pral EM,da Silva S,Bijovsky AT,Mortara RA,Alfieri SC

更新日期：1998-02-01 00:00:00

abstract：:A beta-1,3-glucan-binding lectin from the penetration glands of Diplostomum pseudospathaceum cercariae was isolated by affinity chromatography using yeast glucan and curdlan as affinity matrices. Further purification to homogeneity was performed by cation-exchange chromatography. The protein migrated as a double band ...

journal_title：Parasitology

authors： Mikes L,Man P

更新日期：2003-07-01 00:00:00

abstract：:In this study, the proteome of axenically grown Entamoeba histolytica parasites was explored by two-dimensional gel electrophoresis (2-DE), employing a practical and effective procedure for the solubilization of E. histolytica proteins. Approximately 900 protein species in the pH range between 4 and 7 were detected by...

journal_title：Parasitology

authors： Tolstrup J,Krause E,Tannich E,Bruchhaus I

更新日期：2007-02-01 00:00:00

abstract：:Sequence comparisons have recently shown that the Schistosoma mansoni protein Sm32 is similar to asparaginyl endoproteinases, a novel family of cysteine proteinases, of which the legumains from legumes are the best characterized. By synthesizing and employing fluorogenic peptide substrates for the specific detection o...

journal_title：Parasitology

authors： Dalton JP,Hola-Jamriska L,Brindley PJ

更新日期：1995-12-01 00:00:00

abstract：:Intact surface membrane vesicles were obtained and purified from the schistosomula of Schistosoma mansoni. The method of preparation of the vesicles involved treating the schistosomula in a buffered high salt medium for 1 h at 4 degrees C (Step 1), and then for 1 h at 25-37 degrees C (Step 2). Vesicles were formed fro...

journal_title：Parasitology

authors： Kusel JR,Gazzinelli G,Colley DG,de Souza CP,Cordeiro MN

更新日期：1984-12-01 00:00:00

abstract：:Leishmania produce several types of mucin-like glycoproteins called proteophosphoglycans (PPGs) some of which are secreted while others are found on the surface of promastigotes and amastigotes. These proteins are thought to be important in the transmission, invasion and subsequent intracellular survival of parasites....

journal_title：Parasitology

authors： Samant M,Sahasrabuddhe AA,Singh N,Gupta SK,Sundar S,Dube A

更新日期：2007-08-01 00:00:00

abstract：:The evolution of host specificity and the potential trade-off between being a generalist and a specialist are central issues in the evolutionary ecology of parasites. Different species of parasites or even different populations of the same species often show different degrees of host specificity. However, less is know...

journal_title：Parasitology

authors： Leung TL,Poulin R

更新日期：2010-02-01 00:00:00

abstract：:Genome sequencing has greatly contributed to our understanding of parasitic protozoa. This is particularly the case for Cryptosporidium species (phylum Apicomplexa) which are difficult to propagate. Because of their polymorphic nature, simple sequence repeats have been used extensively as genotypic markers to differen...

journal_title：Parasitology

authors： Widmer G

更新日期：2018-08-01 00:00:00

abstract：:As more facts emerge regarding the ways in which E. multilocularis-derived molecules trigger the host immune response and modulate the host-parasite interplay, it becomes possible to envisage how the parasite can survive and proliferate in its intermediate host, while in other hosts it dies out. Through effects on cel...

journal_title：Parasitology

authors： Mejri N,Hemphill A,Gottstein B

更新日期：2010-03-01 00:00:00

abstract：:Acetylcholinesterase (AChE) is present in all stages of the life-cycle of schistosomes and is located in muscle and on the surface of the parasite. Metrifonate is a drug that inhibits AChE. We compared the AChEs from three schistosome species (Schistosoma mansoni, Schistosoma haematobium and Schistosoma bovis) that ha...

journal_title：Parasitology

authors： Camacho M,Tarrab-Hazdai R,Espinoza B,Arnon R,Agnew A

更新日期：1994-02-01 00:00:00

abstract：:Host behavioural modification by parasites is a common and well-documented phenomenon. However, knowledge on the complexity and specificity of the underlying mechanisms is limited, and host specificity among manipulating parasites has rarely been experimentally verified. We tested the hypothesis that the ability to in...

journal_title：Parasitology

authors： Hernandez RN,Fredensborg BL

更新日期：2015-11-01 00:00:00

abstract：:A striking feature of toxoplasmic seroconversion is the prominent and early IgM response to a low molecular weight antigen of 4-5 kDa. Two different monoclonal antibodies directed against the 4-5 kDa antigen have been generated and used to characterize this molecule. Using these monoclonal antibodies, we could demonst...

journal_title：Parasitology

authors： Tomavo S,Couvreur G,Leriche MA,Sadak A,Achbarou A,Fortier B,Dubremetz JF

更新日期：1994-02-01 00:00:00

abstract：:The transmission success of Onchocerca volvulus is thought to be influenced by a variety of regulatory or density-dependent processes that act at various points in the two-host life-cycle. This paper examines one component of the life-cycle, namely, the ingestion of microfilariae by the simuliid vector, to assess the ...

journal_title：Parasitology

authors： Basáñez MG,Boussinesq M,Prod'hon J,Frontado H,Villamizar NJ,Medley GF,Anderson RM

更新日期：1994-01-01 00:00:00

abstract：:Parasites of the genera Plasmodium and Haemoproteus (Apicomplexa: Haemosporida) are a diverse group of pathogens that infect birds nearly worldwide. Despite their ubiquity, the ecological and evolutionary factors that shape the diversity and distribution of these protozoan parasites among avian communities and geograp...

journal_title：Parasitology

authors： Fecchio A,Svensson-Coelho M,Bell J,Ellis VA,Medeiros MC,Trisos CH,Blake JG,Loiselle BA,Tobias JA,Fanti R,Coffey ED,DE Faria IP,Pinho JB,Felix G,Braga EM,Anciães M,Tkach V,Bates J,Witt C,Weckstein JD,Ricklefs RE,

更新日期：2017-06-01 00:00:00

abstract：:The capacity of Acanthocheilonema viteae to metabolize fructose was investigated in vitro. In common with other filarial species A. viteae oxidized fructose to lactate but its rate of consumption was only 40% of the glucose-containing control value. Fructose was not incorporated into glycogen. Release of 14CO2 from [U...

journal_title：Parasitology

authors： Hayes DJ,Carter NS

更新日期：1990-12-01 00:00:00

abstract：:A molecular approach was used to genetically characterize 5 species (Aoruroides queenslandensis, Blattophila sphaerolaima, Cordonicola gibsoni, Desmicola ornata and Leidynemella fusiformis) belonging to the superfamily Thelastomatoidea (Nematoda: Oxyurida), a group of pinworms that parasitizes terrestrial arthropods. ...

journal_title：Parasitology

authors： Jex AR,Hu M,Rose HA,Schneider M,Cribb TH,Gasser RB

更新日期：2006-07-01 00:00:00

abstract：:The gastrointestinal nematodes (GIN) stand out as an important cause of disease in small ruminant, especially on goat farm. Widespread resistance to synthetic anthelminthics has stimulated the research for alternative strategies of parasite control, including the use of medicinal plants. The present work summarizes th...

journal_title：Parasitology

authors： Oliveira Santos F,Ponce Morais Cerqueira A,Branco A,José Moreira Batatinha M,Borges Botura M

更新日期：2019-09-01 00:00:00

abstract：:Glucose uptake was examined in adult specimens of Proterometra macrostoma (Trematoda: Digenea) recovered from the stomach (endoparasites) and gills (ectoparasites) of longear sunfish, Lepomis megalotis. The endoparasitic forms transported glucose directly through the external body surface by Na+-independent, facilitat...

journal_title：Parasitology

authors： Uglem GL

更新日期：1987-02-01 00:00:00

abstract：:Malaria remains a major cause of human morbidity and mortality worldwide. Plasmodium falciparum, the most virulent of the 4 human Plasmodium species causing malaria, is potentially life threatening, is increasing in prevalence and is becoming even more resistant to in-use drugs. In light of the growing problem of mult...

journal_title：Parasitology

authors： Mahajan SS,Kamath VR,Ghatpande SS

更新日期：2005-10-01 00:00:00

abstract：:Members of the phylum Microspora are a group of unusual, obligate intracellular eukaryotic parasites that infect a wide range of hosts. However, there are a limited number of microsporidial infections reported in avian hosts, and no parasite species has been defined as an avian pathogen. A microsporidian organism was ...

journal_title：Parasitology

authors： Snowden KF,Logan K,Phalen DN

更新日期：2000-07-01 00:00:00

abstract：:The major transaminase in Heligmosomoides polygyrus, Panagrellus redivivus and rat liver was the 2-oxoglutarate-glutamate system, with relatively few amino acids acting as donors for the pyruvate-alanine and oxaloacetate-aspartate systems. The relative effectiveness of the different amino acid donors in the three tran...

journal_title：Parasitology

authors： Grantham BD,Barrett J

更新日期：1986-12-01 00:00:00